All Clinical Trials in Canada

A listing of 3904 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

Home

Canada

Show Filters

Match to Clinical Trials

Access to cutting-edge treatments

Latest clinical trials

Find trials in your area

Start Matching

Filter by Age

Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery

NCT05111574

Recruiting

This phase II trial tests whether nivolumab in combination with cabozantinib works in patients with mucosal melanoma. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It works by blocking the action of an abnormal protein that signals tumor cells to multiply. T... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/15/2025

Locations: Sutter Auburn Faith Hospital, Auburn, California +145 locations

Sutter Auburn Faith Hospital, Auburn, California

Alta Bates Summit Medical Center-Herrick Campus, Berkeley, California

Palo Alto Medical Foundation-Fremont, Fremont, California

Keck Medicine of USC Koreatown, Los Angeles, California

Los Angeles General Medical Center, Los Angeles, California

USC / Norris Comprehensive Cancer Center, Los Angeles, California

Memorial Medical Center, Modesto, California

USC Norris Oncology/Hematology-Newport Beach, Newport Beach, California

Palo Alto Medical Foundation Health Care, Palo Alto, California

Stanford Cancer Institute Palo Alto, Palo Alto, California

Sutter Roseville Medical Center, Roseville, California

Sutter Medical Center Sacramento, Sacramento, California

California Pacific Medical Center-Pacific Campus, San Francisco, California

UCSF Medical Center-Mission Bay, San Francisco, California

Mills Health Center, San Mateo, California

Palo Alto Medical Foundation-Santa Cruz, Santa Cruz, California

Sutter Pacific Medical Foundation, Santa Rosa, California

Palo Alto Medical Foundation-Sunnyvale, Sunnyvale, California

Sutter Solano Medical Center/Cancer Center, Vallejo, California

The Melanoma and Skin Cancer Institute, Englewood, Colorado

UM Sylvester Comprehensive Cancer Center at Aventura, Aventura, Florida

UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables, Florida

UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

UM Sylvester Comprehensive Cancer Center at Plantation, Plantation, Florida

Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho

Saint Alphonsus Cancer Care Center-Caldwell, Caldwell, Idaho

Kootenai Health - Coeur d'Alene, Coeur d'Alene, Idaho

Saint Alphonsus Cancer Care Center-Nampa, Nampa, Idaho

Kootenai Clinic Cancer Services - Post Falls, Post Falls, Idaho

Kootenai Clinic Cancer Services - Sandpoint, Sandpoint, Idaho

Rush-Copley Medical Center, Aurora, Illinois

Centralia Oncology Clinic, Centralia, Illinois

Northwestern University, Chicago, Illinois

Carle at The Riverfront, Danville, Illinois

Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois

Decatur Memorial Hospital, Decatur, Illinois

Northwestern Medicine Cancer Center Kishwaukee, DeKalb, Illinois

Carle Physician Group-Effingham, Effingham, Illinois

Crossroads Cancer Center, Effingham, Illinois

Northwestern Medicine Cancer Center Delnor, Geneva, Illinois

Northwestern Medicine Glenview Outpatient Center, Glenview, Illinois

Northwestern Medicine Grayslake Outpatient Center, Grayslake, Illinois

Northwestern Medicine Lake Forest Hospital, Lake Forest, Illinois

Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois

Cancer Care Center of O'Fallon, O'Fallon, Illinois

Northwestern Medicine Orland Park, Orland Park, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Springfield Clinic, Springfield, Illinois

Springfield Memorial Hospital, Springfield, Illinois

Carle Cancer Center, Urbana, Illinois

Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois

Rush-Copley Healthcare Center, Yorkville, Illinois

Mary Greeley Medical Center, Ames, Iowa

McFarland Clinic - Ames, Ames, Iowa

UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny, Iowa

McFarland Clinic - Boone, Boone, Iowa

UI Health Care Mission Cancer and Blood - West Des Moines Clinic, Clive, Iowa

Mercy Medical Center - Des Moines, Des Moines, Iowa

UI Health Care Mission Cancer and Blood - Laurel Clinic, Des Moines, Iowa

McFarland Clinic - Trinity Cancer Center, Fort Dodge, Iowa

McFarland Clinic - Jefferson, Jefferson, Iowa

McFarland Clinic - Marshalltown, Marshalltown, Iowa

UI Health Care Mission Cancer and Blood - Waukee Clinic, Waukee, Iowa

Dana-Farber Cancer Institute, Boston, Massachusetts

Bronson Battle Creek, Battle Creek, Michigan

Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids, Michigan

Trinity Health Grand Rapids Hospital, Grand Rapids, Michigan

Bronson Methodist Hospital, Kalamazoo, Michigan

West Michigan Cancer Center, Kalamazoo, Michigan

Beacon Kalamazoo Cancer Center, Kalamazoo, Michigan

Trinity Health Muskegon Hospital, Muskegon, Michigan

Corewell Health Lakeland Hospitals - Niles Hospital, Niles, Michigan

Cancer and Hematology Centers of Western Michigan - Norton Shores, Norton Shores, Michigan

Corewell Health Reed City Hospital, Reed City, Michigan

Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center, Saint Joseph, Michigan

Munson Medical Center, Traverse City, Michigan

University of Michigan Health - West, Wyoming, Michigan

Minnesota Oncology - Burnsville, Burnsville, Minnesota

Mercy Hospital, Coon Rapids, Minnesota

Fairview Southdale Hospital, Edina, Minnesota

Abbott-Northwestern Hospital, Minneapolis, Minnesota

North Memorial Medical Health Center, Robbinsdale, Minnesota

Mayo Clinic in Rochester, Rochester, Minnesota

Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota

Regions Hospital, Saint Paul, Minnesota

United Hospital, Saint Paul, Minnesota

Parkland Health Center - Farmington, Farmington, Missouri

Missouri Baptist Medical Center, Saint Louis, Missouri

Sainte Genevieve County Memorial Hospital, Sainte Genevieve, Missouri

Missouri Baptist Sullivan Hospital, Sullivan, Missouri

BJC Outpatient Center at Sunset Hills, Sunset Hills, Missouri

Community Hospital of Anaconda, Anaconda, Montana

Billings Clinic Cancer Center, Billings, Montana

Bozeman Health Deaconess Hospital, Bozeman, Montana

Benefis Sletten Cancer Institute, Great Falls, Montana

Logan Health Medical Center, Kalispell, Montana

Community Medical Center, Missoula, Montana

Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey

Hematology Oncology Associates of CNY at Camillus, Camillus, New York

Hematology Oncology Associates of Central New York-East Syracuse, East Syracuse, New York

Memorial Sloan Kettering Westchester, Harrison, New York

Northwell Health/Center for Advanced Medicine, Lake Success, New York

NYU Langone Hospital - Long Island, Mineola, New York

Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

Miami Valley Hospital South, Centerville, Ohio

Good Samaritan Hospital - Cincinnati, Cincinnati, Ohio

Case Western Reserve University, Cleveland, Ohio

Miami Valley Hospital, Dayton, Ohio

Premier Blood and Cancer Center, Dayton, Ohio

Dayton Physician LLC - Englewood, Dayton, Ohio

Miami Valley Hospital North, Dayton, Ohio

Atrium Medical Center-Middletown Regional Hospital, Franklin, Ohio

Miami Valley Cancer Care and Infusion, Greenville, Ohio

Kettering Medical Center, Kettering, Ohio

Upper Valley Medical Center, Troy, Ohio

Cancer Centers of Southwest Oklahoma Research, Lawton, Oklahoma

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Saint Alphonsus Cancer Care Center-Ontario, Ontario, Oregon

Thomas Jefferson University Hospital, Philadelphia, Pennsylvania

University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania

Asplundh Cancer Pavilion, Willow Grove, Pennsylvania

Rapid City Regional Hospital, Rapid City, South Dakota

Avera Cancer Institute, Sioux Falls, South Dakota

M D Anderson Cancer Center, Houston, Texas

VCU Massey Cancer Center at Stony Point, Richmond, Virginia

VCU Massey Comprehensive Cancer Center, Richmond, Virginia

HSHS Sacred Heart Hospital, Eau Claire, Wisconsin

Marshfield Medical Center-EC Cancer Center, Eau Claire, Wisconsin

Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin

Saint Vincent Hospital Cancer Center at Saint Mary's, Green Bay, Wisconsin

University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison, Wisconsin

University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin

Marshfield Medical Center - Minocqua, Minocqua, Wisconsin

Saint Vincent Hospital Cancer Center at Oconto Falls, Oconto Falls, Wisconsin

Marshfield Medical Center-Rice Lake, Rice Lake, Wisconsin

Saint Vincent Hospital Cancer Center at Sheboygan, Sheboygan, Wisconsin

Marshfield Medical Center-River Region at Stevens Point, Stevens Point, Wisconsin

Saint Vincent Hospital Cancer Center at Sturgeon Bay, Sturgeon Bay, Wisconsin

Marshfield Medical Center - Weston, Weston, Wisconsin

Ottawa Hospital and Cancer Center-General Campus, Ottawa, Ontario

Odette Cancer Centre- Sunnybrook Health Sciences Centre, Toronto, Ontario

University Health Network-Princess Margaret Hospital, Toronto, Ontario

Jewish General Hospital, Montreal, Quebec

Conditions: Anal Melanoma, Bladder Melanoma, Cervical Melanoma, Esophageal Melanoma, Gallbladder Melanoma, Mucosal Melanoma, Oral Cavity Mucosal Melanoma, Penile Mucosal Melanoma, Rectal Melanoma, Recurrent Mucosal Melanoma, Sinonasal Mucosal Melanoma, Urethral Melanoma, Vaginal Melanoma, Vulvar Melanoma, Head and Neck Mucosal Melanoma, Nasopharyngeal Mucosal Melanoma, Urinary System Mucosal Melanoma

Learn More ›

The SPECTRUM Study: An Observational Study to Learn More About How Well Aflibercept 8 mg Works in Treating Visual Impairment Due to Neovascular Age-related Macular Degeneration or Diabetic Macula Edema

NCT06075147

Recruiting

This is an observational study in which only data are collected from people who have already been prescribed aflibercept 8 mg by their own doctors. In this study, data from adults with visual impairment due to neovascular age-related macular degeneration (nAMD) or diabetic macula edema (DME) will be collected and studied. Visual impairment is any degree of vision loss that affects a person's ability to perform daily activities. nAMD is an eye disorder that causes vision loss due to the growth of abnormal blood vessels that leak blood or retinal fluid into the macula (the central part of the retina). nAMD is a leading cause of vision loss for people aged 50 and older. DME is a diabetes-related eye disorder. In DME, the macula swells up due to fluid leakage from damaged blood vessels, resulting in vision problems. Aflibercept 8 mg is a drug that is injected into the eye. It works by blocking a protein called vascular endothelial growth factor (VEGF) which causes abnormal growth and leakage of blood vessels at the back of the eye. Aflibercept 8 mg has been submitted for approval for the treatment of visual impairment due to nAMD and DME based on the results from 2 studies called PHOTON and PULSAR. This study will begin once approval is obtained. Currently, no real-world data are available for aflibercept 8 mg. The main purpose of this study is to collect more information about how well aflibercept 8 mg injection works in people with nAMD and DME. This study will include participants who have not received any prior treatment for nAMD or DME and participants who have. The main information that researchers will collect: the change in vision test scores called the best corrected visual acuity (BCVA) after 12 months of treatment. Data will be collected from February 2024 to September 2027 and will cover a period of up to 24 months per participant. The data will be collected using medical records and by interviewing the patients during regular visits that take place in routine practice. Researchers will observe participants from the first injection of aflibercept 8 mg until the end of the observation. In this study, only available data from regular visits will be collected. No visits or tests are required as part of this study. Read Less

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/15/2025

Locations: Many Locations, Multiple Locations, Not set +17 locations

Conditions: Visual Impairment, Neovascular Age-related Macular Degeneration (nAMD), Diabetic Macula Edema (DME)

Learn More ›

A Study Comparing Teclistamab Monotherapy Versus Pomalidomide, Bortezomib, Dexamethasone (PVd) or Carfilzomib, Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma

NCT05572515

Recruiting

The purpose of this study is to compare the efficacy of teclistamab with PVd/Kd in Part 1 and to further characterize safety and efficacy of an alternative dosing for teclistamab in Part 2 in participants with relapsed or refractory multiple myeloma.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/15/2025

Locations: Alaska Oncology and Hematology LLC, Anchorage, Alaska +209 locations

Alaska Oncology and Hematology LLC, Anchorage, Alaska

Banner MD Anderson Cancer Center, Gilbert, Arizona

Alta Bates Comprehensive Cancer Center, Berkeley, California

MemorialCare Long Beach Medical Center, Long Beach, California

University of California Irvine, Orange, California

PIH Health Hospital, Whittier, California

Rocky Mountain Cancer Centers, Aurora, Colorado

University of Connecticut, Farmington, Connecticut

University of Miami Sylvester Cancer Center, Miami, Florida

Orlando Health Cancer Institute, Orlando, Florida

Cleveland Clinic Florida, Weston, Florida

Mission Cancer Blood, Waukee, Iowa

East Jefferson General Hospital Bone Marrow Transport Clinic, Metairie, Louisiana

Walter Reed National Military Medical Center, Bethesda, Maryland

Maryland Oncology Hematology P A, Silver Spring, Maryland

Boston University Medical Center, Boston, Massachusetts

Saint Lukes Hospital Saint Lukes Cancer Specialists, Chesterfield, Missouri

Cooper Health System MD Anderson Cancer Center at Cooper, Camden, New Jersey

Herbert Irving Comprehensive Cancer Center Columbia University Medical Center, New York, New York

Durham VAMC, Durham, North Carolina

Penn Medicine Lancaster General Health, Lancaster, Pennsylvania

Tennessee Oncology, Nashville, Tennessee

Brooke Army Medical Center, Fort Sam Houston, Texas

Baylor College of Medicine, Houston, Texas

Michael E DeBakey VA Medical Center, Houston, Texas

Harris Health Smith Clinic, Houston, Texas

Utah Cancer Specialists, Salt Lake City, Utah

Alexander T. Augusta Military Medical Center, Fort Belvoir, Virginia

Virginia Oncology Associates, Norfolk, Virginia

NorthWest Medical Specialties, PLLC, Tacoma, Washington

Blacktown Hospital, Blacktown, Not set

St Vincents Hospital Melbourne, Fitzroy, Not set

Box Hill Hospital, Melbourne, Not set

Fiona Stanley Hospital, Murdoch, Not set

Sir Charles Gairdner Hospital, Nedlands, Not set

LKH - Universitätsklinikum der PMU Salzburg, Salzburg, Not set

Medical University Vienna MUV, Vienna, Not set

Algemeen Ziekenhuis Klina, Brasschaat, Not set

Jolimont, Haine-St-Paul, Not set

Az Groeninge, Kortrijk, Not set

Universitair Ziekenhuis Gasthuisberg, Leuven, Not set

CHR de la Citadelle, Liege, Not set

Hospitais Integradaos da Gavea S/A - DF Star, Brasilia, Not set

Fundacao Universidade de Caxias do Sul, Caxias do Sul, Not set

Liga Paranaense de Combate ao Cancer, Curitiba, Not set

Instituto Joinvilense de Hematologia e Oncologia Ltda Centro de Hematologia e Oncologia, Joinville, Not set

Liga Norte Riograndense Contra O Cancer, Natal, Not set

Complexo Hospitalar de Niteroi, Niteroi, Not set

Instituto de Educacao, Pesquisa e Gestao em Saude Instituto Americas (COI), Rio de Janeiro, Not set

Hospital Sao Rafael, Salvador, Not set

Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto Hospital de Base, Sao Jose do Rio Preto, Not set

Sociedade Beneficente de Senhoras Hospital Sirio Libanes, Sao Paulo, Not set

Instituto D Or de Pesquisa e Ensino IDOR, Sao Paulo, Not set

Fundacao Antonio Prudente A C Camargo Cancer Center, Sao Paulo, Not set

Clinica Medica Sao Germano LTDA, Sao Paulo, Not set

Real e Benemérita Associação Portuguesa de Beneficência, São Paulo, Not set

Hospital Alemao Oswaldo Cruz, São Paulo, Not set

Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein, São Paulo, Not set

Arthur J E Child Comprehensive Cancer Centre, Calgary, Alberta

Saint John Regional Hospital, Saint John, New Brunswick

Brampton Civic Hospital, Brampton, Ontario

Lakeridge Health Oshawa, Oshawa, Ontario

CIUSSS de l Est de l Ile de Montreal Installation Hopital Maisonneuve Rosemont, Montreal, Quebec

Beijing Chaoyang Hospital, Beijing, Not set

BeiJing JiShuiTan Hospital, Beijing, Not set

The First Bethune Hospital of Jilin University, Changchun, Not set

The Third Xiangya Hospital, Central South University, Changsha, Not set

Sichuan Provincial Peoples Hospital, Chengdu, Not set

Chongqing University Cancer Hospital, Chongqing, Not set

Fujian Meidical University Union Hospital, Fu Zhou, Not set

Sun Yat -Sen University Cancer Center, Guangzhou, Not set

First affiliated Hospital of Zhejiang University, Hangzhou, Not set

Harbin medical university cancer hospital, Harbin, Not set

The First Affiliated Hospital of NanChang University, Nanchang, Not set

Nanjing Drum Tower Hospital, Nanjing, Not set

First Affiliated Hospital of Guangxi Medical University, Nanning, Not set

Shanghai Fourth People s Hospital, Shanghai, Not set

Shengjing Hospital Of China Medical University, Shenyang, Not set

Shenzhen 2nd People's Hospital, Shenzhen, Not set

Institute of Hematology and Blood Diseases Hospital, Tian Jin, Not set

Tianjin Medical University Cancer Institute and Hospital, Tianjin, Not set

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Not set

Wuhan Union Hospital, Wuhan, Not set

Wuxi People s Hospital, Wuxi, Not set

The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Not set

Henan Cancer Hospital, Zhengzhou, Not set

Fakultni nemocnice Brno, Brno, Not set

Fakultni nemocnice Olomouc, Olomouc, Not set

Fakultni Nemocnice Ostrava, Ostrava - Poruba, Not set

Vseobecna fakultni nemocnice v Praze, Praha 2, Not set

Aalborg University Hospital, Aalborg, Not set

Aarhus University Hospital, Aarhus, Not set

Rigshospitalet, Copenhagen, Not set

Regionshospitalet Godstrup, Herning, Not set

Odense Universitetshospital, Odense C, Not set

Vejle Sygehus, Vejle, Not set

CHU Amiens - Hopital Sud, AMIENS cedex 1, Not set

Hôpital Côte de Nacre, Caen cedex 9, Not set

CHU Grenoble, Grenoble, Not set

Centre Hospitalier du Mans, Le Mans, Not set

Hopital Saint Vincent de Paul, Lille, Not set

CHU de Montpellier Hopital Saint Eloi, Montpellier, Not set

CHU Nantes, Nantes Cedex 1, Not set

Hopital Saint-Antoine, Paris, Not set

Hopital de la Pitie Salpetriere, Paris, Not set

Hopital Necker Enfants Malades, Paris, Not set

Institut Universitaire du Cancer Toulouse Oncopole, Toulouse, Not set

CHU de Nancy - Hopital de Brabois, Vandœuvre-lès-Nancy, Not set

Medizinische Universitat Lausitz Carl Thiem, Cottbus, Not set

Universitatsklinikum Carl Gustav Carus Dresden, Dresden, Not set

Universitätsmedizin Greifswald, Greifswald, Not set

Asklepios Klinik Altona, Hamburg, Not set

Universitaetsklinikum Heidelberg, Heidelberg, Not set

Universitaetsklinikum Giessen und Marburg GmbH, Marburg, Not set

Universitatsklinikum Tubingen, Tübingen, Not set

Universitatsklinikum Ulm, Ulm, Not set

Heinrich-Braun-Klinikum gGmbH, Zwickau, Not set

Alexandra General Hospital of Athens, Athens Attica, Not set

Agios Andreas General Hospital of Patra, Patra, Not set

G Papanikolaou Hospital of Thessaloniki, Thessaloniki, Not set

Fortis Memorial Research Institute, Gurgaon, Not set

Bhagwan Mahaveer Cancer Hospital & Research Centre, Jaipur, Not set

Deenanath Mangeshkar Hospital and Research Centre, Pune, Not set

Hillel Yaffe Medical Center, Hadera, Not set

Bnai Zion Medical Center, Haifa, Not set

Carmel Medical Center, Haifa, Not set

Rabin Medical Center, Petah Tikva, Not set

Sheba Medical Center, Ramat Gan, Not set

Tel Aviv Sourasky Medical Center, Tel-Aviv, Not set

A O U Sant Orsola Malpighi, Bologna, Not set

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Not set

Azienda Ospedaliero Universitaria Policlinico Paolo Giaccone, Palermo, Not set

Ospedale Santa Chiara AO Universitaria Pisana, Pisa, Not set

Arcispedale Santa Maria Nuova - IRCCS, Reggio Emilia, Not set

Campus Bio Medico di Roma, Roma, Not set

A O Universitaria Senese Ospedale Santa Maria alle Scotte, Siena, Not set

A.O.U. Citta della Salute e della Scienza di Torino - Presidio Molinette, Turin, Not set

ASUI Santa Maria della Misericordia di Udine, Udine, Not set

Ospedale di Circolo e Fondazione Macchi, Varese, Not set

Institute of Science Tokyo Hospital, Bunkyo ku, Not set

Chiba Cancer Center, Chiba, Not set

Ogaki Municipal Hospital, Gifu, Not set

National Hospital Organization Shibukawa Medical Center, Gunma, Not set

Kansai Medical University Hospital, Hirakata, Not set

Hitachi General Hospital, Hitachi, Not set

Saitama Medical University Hospital, Iruma-gun, Not set

Kameda Medical Center, Kamogawa City, Not set

National Cancer Center Hospital East, Kashiwa, Not set

Kurashiki Central Hospital, Kurashiki, Not set

Matsuyama Red Cross Hospital, Matsuyama, Not set

Aichi Medical University Hospital, Nagakute, Not set

JRC Nagasaki Genbaku Hospital, Nagasaki-Shi, Not set

Niigata University Medical And Dental Hospital, Niigata, Not set

National Hospital Organization Okayama Medical Center, Okayama, Not set

Osaka Metropolitan University Hospital, Osaka, Not set

Hokkaido University Hospital, Sapporo, Not set

Juntendo University Hospital, Tokyo, Not set

The Cancer Institute Hospital of JFCR, Tokyo, Not set

Yamagata University Hospital, Yamagata, Not set

Yamanashi Prefectural Central Hospital, Yamanashi, Not set

Hospital Pulau Pinang, Georgetown, Not set

Hospital Queen Elizabeth, Kota Kinabalu, Not set

University Malaya Medical Centre, Kuala Lumpur, Not set

Subang Jaya Medical Centre, Subang Jaya, Not set

Meander Medisch Centrum, Amersfoort, Not set

VUMC Amsterdam, Amsterdam, Not set

Universitair Medisch Centrum Groningen, Groningen, Not set

UMC Utrecht, Utrecht, Not set

Uniwersyteckie Centrum Kliniczne, Gdansk, Not set

Pratia Onkologia Katowice, Katowice, Not set

Swietokrzyskie Centrum Onkologii SPZOZ w Kielcach, Kielce, Not set

Uniwersytecki Szpital Kliniczny Nr 1 w Lublinie, Lublin, Not set

Uls Almada Seixal - Hosp. Garcia de Orta, Almada, Not set

Uls Braga - Hosp. Braga, Braga, Not set

Champalimaud Foundation Champalimaud Centre, Lisbon, Not set

Instituto Portugues de Oncologia, Porto, Not set

Uls Gaia Espinho, Vila Nova de Gaia, Not set

Hosp. Univ. Germans Trias I Pujol, Badalona, Not set

Institut Catala d Oncologia L Hospitalet, Hospitalet de Llobregat, Not set

Hosp. de Jerez de La Frontera, Jerez de la Frontera, Not set

Hosp. de Leon, Leon, Not set

Hosp. Univ. Infanta Leonor, Madrid, Not set

Hosp. Univ. Ramon Y Cajal, Madrid, Not set

Hosp. Univ. 12 de Octubre, Madrid, Not set

Hosp. Gral. Univ. J.M. Morales Meseguer, Murcia, Not set

Hospital Universitario Central de Asturias, Oviedo, Not set

Hosp. Son Llatzer, Palma de Mallorca, Not set

Hosp. Montecelo, Pontevedra, Not set

Hosp. Quiron Madrid Pozuelo, Pozuelo de Alarcon, Not set

Hospital Universitari i Politecnic La Fe, València, Not set

Falu Lasarett Medicinkliniken Falun, Falun, Not set

Helsingborgs lasarett, Helsingborg, Not set

Akademiska Sjukhuset, Uppsala, Not set

Ankara Gulhane Training and Research Hospital, Ankara, Not set

Dr Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara, Not set

Ankara University Medical Faculty, Ankara, Not set

Liv Hospital Ankara, Ankara, Not set

Antalya Training And Research Hospital, Antalya, Not set

Ondokuz Mayis University, Atakum, Not set

Pamukkale University Medical Faculty, Denizli, Not set

Medipol University Hospital, Istanbul, Not set

Aberdeen Royal Infirmary, Aberdeen, Not set

University Hospitals Birmingham NHS Foundation Trust, Birmingham, Not set

Colchester Hospital University NHS, Colchester, Not set

The Clatterbridge Cancer Centre, Liverpool, Not set

Chelsea And Westminster Hospital, London, Not set

St Georges Hospital, London, Not set

James Cook University Hospital, Middlesborough, Not set

Norfolk and Norwich University Hospital, Norwich, Not set

Royal Stoke University Hospital, Staffordshire, Not set

Conditions: Relapsed or Refractory Multiple Myeloma

Learn More ›

Online Prehabilitation for Patients Awaiting Liver Transplantation

NCT05899231

Recruiting

Physical frailty is common in patients awaiting liver transplantation and has been associated with poor health outcomes. There is promising data from small studies showing that behavioural, nutrition, exercise therapy (prehabilitation) improves physical function in patients while they are waiting for a liver transplant. The proposed trial will assess if a 12-week online prehabilitation program improves physical function in patients listed for liver transplantation. Over 4 years, 177 patients wi... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/15/2025

Locations: Foothills Medical Centre, Calgary, Alberta +5 locations

Conditions: Cirrhosis, Liver, Liver Transplant Surgery, Liver Disease

Learn More ›

Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia

NCT05386394

Recruiting

While many have strongly suggested that transcranial direct current stimulation (tDCS) may represent a beneficial intervention for patients with primary progressive aphasia (PPA), this promising technology has not yet been applied widely in clinical settings. This treatment gap is underscored by the absence of any neurally-focused standard-of-care treatments to mitigate the devastating impact of aphasia on patients' family, work, and social lives. Given that tDCS is inexpensive, easy to use (it... Read More

Gender:

ALL

Ages:

Between 50 years and 90 years

Trial Updated:

08/15/2025

Locations: Johns Hopkins Hospital, Baltimore, Maryland +2 locations

Conditions: Primary Progressive Aphasia, Logopenic Progressive Aphasia, Non-Fluent Primary Progressive Aphasia

Learn More ›

Adaptive Actions and Alcohol Use Outcomes During Internet-delivered Cognitive Behaviour Therapy

NCT07021053

Recruiting

This observational study investigates an Internet-delivered Cognitive Behaviour Therapy (ICBT) intervention for alcohol misuse, called the Alcohol Change Course Enhanced (ACCE). The intervention will be offered through the Online Therapy Unit, which is a routine care ICBT clinic. The primary objective of the study is to examine whether engagement in adaptive actions measured by the Things You Do Questionnaire (TYDQ), including healthy thinking, meaningful activities, social connections, healthy... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/15/2025

Locations: Online Therapy Unit, Regina, Saskatchewan

Conditions: Alcohol Misuse

Learn More ›

A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies

NCT05453903

Recruiting

The purpose of this study is to determine the recommended Phase 2 dose (RP2D) candidate(s) of bleximenib in combination with AML directed therapies (dose selection) and further to evaluate safety and tolerability of bleximenib in combination with AML directed therapies at the RP2D(s) (dose expansion).

Gender:

ALL

Ages:

12 years and above

Trial Updated:

08/15/2025

Locations: The University of Alabama at Birmingham, Birmingham, Alabama +31 locations

The University of Alabama at Birmingham, Birmingham, Alabama

City of Hope, Duarte, California

Massachusetts General Hospital, Boston, Massachusetts

Albert Einstein College Of Medicine, New York, New York

Novant Health, Charlotte, North Carolina

Novant Health Forsyth Medical Center, Winston-Salem, North Carolina

MD Anderson, Houston, Texas

Monash Medical Centre, Clayton, Not set

Peter MacCallum Cancer Centre, Melbourne, Not set

Westmead Hospital, Westmead, Not set

Princess Margaret Cancer Centre University Health Network, Toronto, Ontario

Institut Paoli Calmettes, Marseille Cedex 9, Not set

Chu Rennes Hopital Pontchaillou, Rennes Cedex 9, Not set

Institut Universitaire du Cancer Toulouse Oncopole, Toulouse Cedex 9, Not set

CHU de Tours - Hôpital de Bretonneau, Tours, Not set

Charite Universitaetsmedizin Berlin, Berlin, Not set

Universitatsklinikum Carl Gustav Carus Dresden, Dresden, Not set

Universitaetsklinikum Heidelberg, Heidelberg, Not set

Universitaetsklinikum Leipzig, Leipzig, Not set

Universitatsklinikum Ulm, Ulm, Not set

Azienda Opedaliero-Universitaria Policlinico Sant'orsola Malpighi di Bologna, Bologna, Not set

Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Meldola, Not set

ASST Grande Ospedale Metropolitano Niguarda, Milano, Not set

IRCCS Istituto Clinico Humanitas, Rozzano, Not set

Hosp. de La Santa Creu I Sant Pau, Barcelona, Not set

Hosp Clinic de Barcelona, Barcelona, Not set

Hosp Univ Vall D Hebron, Barcelona, Not set

Hosp Univ Fund Jimenez Diaz, Madrid, Not set

Clinica Univ. de Navarra, Pamplona, Not set

University College London Hospitals NHSFT, London, Not set

Christie Hospital NHS Trust, Manchester, Not set

Oxford University Hospitals NHS Trust, Oxfordshire, Not set

Conditions: Leukemia, Myeloid, Acute

Learn More ›

A Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

NCT06752668

Recruiting

Narcolepsy Type 1 (NT1), Narcolepsy Type 2 (NT2), and Idiopathic Hypersomnia (IH) are rare conditions that make people feel very sleepy during the day (often referred to as excessive daytime sleepiness \[EDS\]). People living with these conditions might find it hard to stay alert and pay attention when they are at school, working, driving, or performing other daily activities. While all conditions result in feeling sleepy, there are some differences in other common symptoms: * NT1: People with... Read More

Gender:

ALL

Ages:

Between 18 years and 65 years

Trial Updated:

08/15/2025

Locations: Auburn, Alabama, Auburn, Alabama +24 locations

Conditions: Narcolepsy Type 1, Narcolepsy Type 2, Idiopathic Hypersomnia

Learn More ›

Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia

NCT04159103

Recruiting

This 3-part, Phase 1/2 study is designed to characterize the safety, tolerability, and pharmacological activity (as assessed by biomarker measurements) and to determine the selected dose of mRNA-3927 in participants with genetically confirmed propionic acidemia (PA). After establishing a dose with an acceptable safety and pharmacodynamic (PD) response for participants ≥1 year of age in Part 1, participants will be enrolled in Part 2 (which will serve as the pivotal study) to allow for determinat... Read More

Gender:

ALL

Ages:

All

Trial Updated:

08/15/2025

Locations: UCSD Altman Clinical and Transalational Research Institute Building, Los Angeles, California +34 locations

UCSD Altman Clinical and Transalational Research Institute Building, Los Angeles, California

Ronald Reagan UCLA Medical Center, Los Angeles, California

Lucile Packard Children's Hospital Stanford, Stanford, California

Nicklaus Children's Hospital, Miami, Florida

University of South Florida - 12901 Bruce B Downs, Tampa, Florida

Johns Hopkins Hospital, Adult Outpatient Clinical Research Unit, Baltimore, Maryland

Boston Children's Hospital, Boston, Massachusetts

University of Michigan Hospitals, Ann Arbor, Michigan

Icahn School of Medicine at Mount Sinai - Clinical Research Unit, New York, New York

Duke University Medical System (Duke Health), Durham, North Carolina

Ann and Robert H Lurie Childrens Hospital of Chicago, Cincinnati, Ohio

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

University Hospitals Cleveland Medical Center - 11100 Euclid Ave, Cleveland, Ohio

Children's Hospital of Philadelphia (CHOP), Philadelphia, Pennsylvania

Texas Children's Hospital, Houston, Texas

Stollery Children's Hospital University of Alberta, Edmonton, Alberta

Hospital For Sick Children, Toronto, Ontario

CHU de Marseille - Hôpital de la Timone, Marseille, Not set

Hôpital Necker - Enfants Malades, Paris, Not set

Fujita Health University Hospital, Toyoake-shi, Aichi

Tohoku University Hospital, Sendai-Shi, Miyagi

National Center for Child Health and Development, Tokyo, Not set

Erasmus MC, Rotterdam, Zuid-Holland

Universitair Medisch Centrum Utrecht - PPDS, Utrecht, Not set

King Faisal Specialist Hospital & Research Center - Riyadh, Riyadh, Ar Riya

King Fahad Medical City, Riyadh, Ar Riya

King Abdullah Children's Specialist Hospital, Riyadh, Ar Riya

Hospital Sant Joan de Deu - PIN, Esplugues de Llobregat, Barcelona

Hospital Universitario Cruces, Barakaldo, Biscay

Hospital Universitario 12 de Octubre, Madrid, Not set

Hospital Universitario Virgen del Rocio - PPDS, Sevilla, Not set

University Hospital Birmingham NHS Foundation Trust, Birmingham, Not set

Birmingham Children's Hospital, Birmingham, Not set

Great Ormond Street Hospital for Children NHS Foundation Trust, London, Not set

Willink Biochemical Genetics Unit - PPDS, Manchester, Not set

Conditions: Propionic Acidemia

Learn More ›

Pilot Feasibility Study of Fecal Microbiota Transplant for the Treatment of Small Intestinal Bacterial Overgrowth

NCT05967871

Recruiting

The objective of the study is to assess feasibility, and clinical efficacy of a novel Fecal Microbiota Transplantation protocol for the treatment of pediatric small intestinal bacterial overgrowth (SIBO).

Gender:

ALL

Ages:

Between 3 years and 18 years

Trial Updated:

08/15/2025

Locations: McMaster Children's Hospital, Hamilton, Ontario +1 locations

Conditions: Small Intestinal Bacterial Overgrowth

Learn More ›

A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)

NCT06459180

Recruiting

This study will have two phases: a sacituzumab tirumotecan safety run-in and a Phase 3 portion. The safety run-in phase will be used to evaluate the efficacy and safety of sacituzumab tirumotecan at the dose for evaluation in the Phase 3 portion. The purpose of this study is to compare the efficacy and safety of sacituzumab tirumotecan versus treatment of physician's choice as second-line treatment for participants with recurrent or metastatic cervical cancer in the Phase 3 portion. The primary... Read More

Gender:

FEMALE

Ages:

18 years and above

Trial Updated:

08/14/2025

Locations: USA Mitchell Cancer Institute-Clinical Trials ( Site 4126), Mobile, Alabama +215 locations

USA Mitchell Cancer Institute-Clinical Trials ( Site 4126), Mobile, Alabama

Providence Alaska Medical Center ( Site 4137), Anchorage, Alaska

HonorHealth (HH) ( Site 8002), Phoenix, Arizona

Arizona Oncology Associates - HOPE ( Site 8001), Tucson, Arizona

Moores Cancer Center-Clinical Trials Office - Gynecological Oncology ( Site 4125), La Jolla, California

UCLA Hematology/Oncology - Westwood (Building 100)-Department of OBGYN, Division of Gynecologic Onc ( Site 4105), Los Angeles, California

Hoag Memorial Hospital Presbyterian ( Site 4104), Newport Beach, California

Mount Sinai Comprehensive Cancer Center ( Site 4143), Miami Beach, Florida

Advent Health ( Site 4140), Orlando, Florida

Florida Cancer Specialists East ( Site 7001), West Palm Beach, Florida

Northside Hospital ( Site 4127), Atlanta, Georgia

Georgia Cancer Center at Augusta University ( Site 4112), Augusta, Georgia

Lewis Cancer and Research Pavilion ( Site 4114), Savannah, Georgia

University Medical Center New Orleans ( Site 4132), New Orleans, Louisiana

Willis Knighton Medical Center ( Site 4101), Shreveport, Louisiana

The Center of Hope ( Site 4106), Reno, Nevada

Holy Name Medical Center ( Site 4117), Teaneck, New Jersey

Optimum Clinical Research Group ( Site 4138), Albuquerque, New Mexico

Duke Cancer Institute ( Site 4120), Durham, North Carolina

University of Cincinnati Medical Center ( Site 4128), Cincinnati, Ohio

The Ohio State University ( Site 4103), Hilliard, Ohio

Oklahoma Cancer Specialists and Research Institute, LLC-Clinical Research ( Site 4116), Tulsa, Oklahoma

Oncology Associates of Oregon, P.C.(Willamette Valley Cancer Institute) (WVCI) ( Site 8007), Eugene, Oregon

Legacy Good Samaritan Medical Center-Oncology Clinical Research ( Site 4115), Portland, Oregon

Sidney Kimmel Cancer Center - Jefferson Health ( Site 4142), Philadelphia, Pennsylvania

Asplundh Cancer Pavilion ( Site 4113), Willow Grove, Pennsylvania

Texas Oncology - DFW ( Site 8003), Fort Worth, Texas

Houston Methodist Hospital OB/GYN ( Site 4102), Houston, Texas

Texas Oncology - San Antonio ( Site 8006), San Antonio, Texas

University of Virginia Cancer Center ( Site 4123), Charlottesville, Virginia

Inova Schar Cancer Institute ( Site 4139), Fairfax, Virginia

Swedish Medical Center-Swedish Cancer Institute ( Site 4134), Seattle, Washington

Hospital Británico de Buenos Aires-Oncology ( Site 0102), Ciudad autónoma de Buenos Aires, Buenos Aires

Instituto de Investigaciones Clínicas Mar del Plata ( Site 0107), Mar del Plata, Buenos Aires

Instituto de Oncología Angel H. Roffo ( Site 0103), Buenos Aires, Caba

Instituto Alexander Fleming ( Site 0108), Buenos Aires, Caba

Sanatorio Allende - Cerro-Oncology ( Site 0106), Córdoba, Cordoba

Hospital Aleman-Oncology ( Site 0100), Buenos Aires, Not set

Centro de Educación Médica e Investigaciones Clínicas (CEMIC) ( Site 0109), Caba, Not set

Fundación CORI para la Investigación y Prevención del Cáncer ( Site 0104), La Rioja, Not set

Blacktown Hospital ( Site 3006), Sydney, New South Wales

Campbelltown Hospital-Macarthur Cancer Therapy Centre Medical Oncology ( Site 3000), Sydney, New South Wales

Royal Brisbane and Women's Hospital ( Site 3001), Herston, Queensland

Monash Health-Oncology Research ( Site 3002), Clayton, Victoria

Peter MacCallum Cancer Centre-Parkville Cancer Clinical Trials Unit (PCCTU) ( Site 3005), Melbourne, Victoria

Sir Charles Gairdner Hospital ( Site 3003), Nedlands, Western Australia

Kepler Universitätsklinikum-Department for Oncology and Hematology ( Site 1002), Linz, Oberosterreich

Medizinische Universität Graz-Abteilung für Gynäkologie / Onkologie ( Site 1003), Graz, Steiermark

Medizinische Universitaet Innsbruck-Univ.-Klinik f. Gynäkologie und Geburtshilfe ( Site 1000), Innsbruck, Tirol

Medizinische Universität Wien ( Site 1001), Wien, Not set

AZORG Campus Aalst-Moorselbaan ( Site 2905), Aalst, Oost-Vlaanderen

UZ Gent-Medical oncology ( Site 2901), Gent, Oost-Vlaanderen

UZ Leuven-Gynecologic Oncology ( Site 2900), Leuven, Vlaams-Brabant

Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart Tilman-Medical Oncology ( Site 2904), Belgium, Wallonne, Region

CHU UCL Namur/Site Sainte Elisabeth-Trial Office ( Site 2902), Namur, Not set

Instituto do Câncer e Transplante de Curitiba ( Site 0205), Curitiba, Parana

Hospital Moinhos de Vento-Centro de Pesquisa Clínica ( Site 0204), Porto Alegre, Rio Grande Do Sul

Hospital do Câncer Mãe de Deus ( Site 0201), Porto Alegre, Rio Grande Do Sul

Centro de Hematologia e Oncologia ( Site 0203), Joinville, Santa Catarina

IBCC - Instituto Brasileiro de Controle do Câncer-Centro de Pesquisa Clínica ( Site 0200), São Paulo, Sao Paulo

Americas Centro de Oncologia Integrado ( Site 0202), Rio de Janeiro, Not set

Hospital Paulistano ( Site 0209), Sao Paulo, Not set

MBAL Uni Hospital-Department of Medical Oncology ( Site 1104), Panagyurishte, Pazardzhik

MHAT - Heart and Brain ( Site 1100), Pleven, Not set

Complex Oncology Center - Plovdiv EOOD ( Site 1102), Plovdiv, Not set

BC Cancer Kelowna ( Site 4007), Kelowna, British Columbia

BC Cancer Surrey ( Site 4006), Surrey, British Columbia

BC Cancer Victoria ( Site 4008), Victoria, British Columbia

Royal Victoria Regional Health Centre ( Site 4009), Barrie, Ontario

McGill University Health Centre ( Site 4000), Montreal, Quebec

Centre Hospitalier de l'Université de Montréal ( Site 4001), Montréal, Quebec

Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 4002), Quebec City, Quebec

FALP-UIDO ( Site 0300), Santiago, Region M. De Santiago

Pontificia Universidad Catolica de Chile ( Site 0302), Santiago, Region M. De Santiago

ONCOCENTRO APYS-ACEREY ( Site 0303), Viña del Mar, Valparaiso

Anhui Provincial Cancer Hospital-Gynecological Oncology ( Site 5040), Hefei, Anhui

Anhui Provincial Hospital ( Site 5011), Hefei, Anhui

Beijing Peking Union Medical College Hospital ( Site 5045), Beijing, Beijing

Chongqing University Cancer Hospital ( Site 5003), Chongqing, Chongqing

Fujian Provincial Cancer Hospial ( Site 5012), Fuzhou, Fujian

The First Affiliated hospital of Xiamen University-Obstetrics and gynecology department ( Site 5027), Xiamen, Fujian

Sun Yat-sen Memorial Hospital, Sun Yat-sen University ( Site 5001), Guangzhou, Guangdong

Sun Yat-sen University Cancer Center-Internal medicine ( Site 5006), Guangzhou, Guangdong

Affiliated Hospital of Guangdong Medical University ( Site 5004), Zhanjiang, Guangdong

Guangxi Medical University Affiliated Tumor Hospital ( Site 5016), Nanning, Guangxi

Hainan General Hospital ( Site 5032), Haikou, Hainan

Harbin Medical University Cancer Hospital ( Site 5010), Harbin, Heilongjiang

The First Affiliated Hospital of Xinxiang Medical University-Oncology ( Site 5041), Xinxiang, Henan

Henan Cancer Hospital ( Site 5026), Zhengzhou, Henan

Wuhan Union Hospital ( Site 5020), Wuhan, Hubei

Hubei Cancer Hospital-Hubei Cancer Hospital ( Site 5019), Wuhan, Hubei

Hunan Cancer Hospital ( Site 5021), Changsha, Hunan

Xiangya Hospital Central South University ( Site 5009), Changsha, Hunan

Jiangsu Province Hospital-Oncology Department ( Site 5018), Nanjing, Jiangsu

Jiangxi Maternal and Child Health Hospital ( Site 5031), Nanchang, Jiangxi

Jilin Province Tumor Hospital ( Site 5036), Changchun, Jilin

The First Affiliated Hospital of Xi'an Jiaotong University ( Site 5007), Xi'an, Shaanxi

Shandong Cancer Hospital ( Site 5014), Jinan, Shandong

LinYi Cancer Hospital-Gastrology department ( Site 5039), Linyi, Shandong

Obstetrics & Gynecology Hospital of Fudan University ( Site 5015), Shanghai, Shanghai

Shanxi Cancer Hospital ( Site 5043), Taiyuan, Shanxi

West China Second University Hospital, Sichuan University ( Site 5017), Chengdu, Sichuan

Sichuan Cancer hospital-Oncology ( Site 5030), Chengdu, Sichuan

Yunnan Province Cancer Hospital-Gynecology Department ( Site 5005), Kunming, Yunnan

Women s Hospital School of Medicine Zhejiang University ( Site 5022), Hangzhou, Zhejiang

Zhejiang Cancer Hospital ( Site 5008), Hangzhou, Zhejiang

The First Affiliated Hospital of Wenzhou Medical University ( Site 5033), Wenzhou, Zhejiang

Sociedad De Oncología y Hematología Del Cesar SAS-Oncology ( Site 0401), Valledupar, Cesar

IMAT S.A.S ( Site 0402), Montería, Cordoba

Instituto Nacional De Cancerologia-Oncología Clínica ( Site 0404), Bogota, Cundinamarca

FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 0403), Bogota., Distrito Capital De Bogota

Oncologos del Occidente ( Site 0405), Pereira., Risaralda

Fundación Valle del Lili ( Site 0406), Cali, Valle Del Cauca

Rigshospitalet-Dept. of Oncology ( Site 1300), Kobenhavn, Hovedstaden

Aarhus Universitetshospital, Skejby ( Site 1301), Aarhus, Midtjylland

Odense Universitetshospital-Department of oncology ( Site 1302), Odense C, Syddanmark

Tampereen yliopistollinen sairaala-Gynecology and Obstetrics ( Site 1404), Tampere, Pirkanmaa

Helsinki University Hospital - Comprehensive Cancer Center (HYKS - Syöpäkeskus) ( Site 1400), Helsinki, Uusimaa

Turku University Hospital-Department of Obstetrics and Gynecology ( Site 1401), Turku, Varsinais-Suomi

Institut de cancérologie Strasbourg Europe (ICANS) ( Site 1501), Strasbourg, Alsace

Institut Bergonié - Centre Régional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest ( Site 1503), Bordeaux, Aquitaine

Centre Jean Perrin - Centre Régional de Lutte contre le Cancer d'Auvergne ( Site 1508), Clermont-Ferrand, Auvergne

Institut Paoli-Calmettes ( Site 1504), Marseille, Bouches-du-Rhone

Hôpital Privé Des Côtes d'Armor ( Site 1510), Plérin, Cotes-d Armor

CHU Besançon ( Site 1507), Besancon, Franche-Comte

Oncopole Claudius Regaud ( Site 1502), Toulouse, Haute-Garonne

Institut Regional du Cancer Montpellier ( Site 1511), Montpellier, Herault

Gustave Roussy ( Site 1512), Villejuif, Ile-de-France

Hôpital privé du Confluent SAS ( Site 1509), Nantes, Loire-Atlantique

CENTRE LEON BERARD ( Site 1505), Lyon Cedex08, Rhone-Alpes

Groupe Hospitalier Diaconesses Croix Saint Simon ( Site 1506), Paris, Not set

Aretaieio Hospital ( Site 1700), Athens, Attiki

Mitera Hospital ( Site 1702), Athens, Attiki

ATTIKON GENERAL UNIVERSITY HOSPITAL ( Site 1703), Chaidari, Attiki

Agios Andreas Hospital Patras ( Site 1701), Patras, Peloponnisos

Cork University Hospital ( Site 1900), Cork, Not set

Mater Misericordiae University Hospital ( Site 1901), Dublin, Not set

St. James's Hospital-Cancer clinical trials office ( Site 1902), Dublin, Not set

Rambam Health Care Campus ( Site 2002), Haifa, Not set

Edith Wolfson Medical Center ( Site 2003), Holon, Not set

Hadassah Medical Center ( Site 2000), Jerusalem, Not set

Sheba Medical Center ( Site 2001), Ramat Gan, Not set

IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlin-DEPARTMENT OF EXPERIMENTAL, DIAGNOSTIC ( Site 2105), Bologna, Emilia-Romagna

Istituto Europeo di Oncologia IRCCS ( Site 2108), Milano, Lombardia

Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Chirurgia Ginecologica ( Site 2107), Milan, Lombardia

Ospedale Humanitas San Pio X ( Site 2113), Milan, Lombardia

Fondazione IRCCS San Gerardo dei Tintori-Oncologia ( Site 2111), Monza, Lombardia

Humanitas University ( Site 2112), Rozzano, Milano

Ospedale Mauriziano-SCDU ONCOLOGIA MEDICA ( Site 2100), Torino, Piemonte

Azienda Ospedaliera Spedali Civili di Brescia-Obstetrics anf gynecology ( Site 2110), Brescia, Not set

Ospedale Cannizzaro ( Site 2104), Catania, Not set

Ospedale San Raffaele. ( Site 2106), Milano, Not set

Istituto Nazionale Tumori IRCCS Fondazione Pascale ( Site 2103), Napoli, Not set

Istituto Oncologico Veneto IRCCS ( Site 2109), Padova, Not set

Fondazione Policlinico Universitario Agostino Gemelli IRCCS -Ginecologia Oncologica ( Site 2102), Roma, Not set

Aichi Cancer Center ( Site 5110), Nagoya, Aichi

National Cancer Center Hospital East ( Site 5113), Kashiwa, Chiba

National Hospital Organization Shikoku Cancer Center ( Site 5109), Matsuyama, Ehime

Ehime University Hospital ( Site 5102), Toon, Ehime

Kurume University Hospital ( Site 5105), Kurume, Fukuoka

Gunma Prefectural Cancer Center ( Site 5116), Ohta, Gunma

Hokkaido University Hospital ( Site 5106), Sapporo, Hokkaido

University of Tsukuba Hospital ( Site 5114), Tsukuba, Ibaraki

Iwate Medical University Hospital ( Site 5112), Shiwa-gun, Iwate

Saitama Medical University International Medical Center ( Site 5117), Hidaka, Saitama

Shizuoka Cancer Center ( Site 5107), Sunto-gun,, Shizuoka

National Cancer Center Hospital ( Site 5108), Chuo, Tokyo

Cancer Institute Hospital of JFCR ( Site 5111), Koto, Tokyo

Keio University Hospital ( Site 5101), Shinjyuku, Tokyo

National Hospital Organization Kyushu Cancer Center ( Site 5104), Fukuoka, Not set

Kagoshima City Hospital ( Site 5115), Kagoshima, Not set

Niigata Cancer Center Hospital ( Site 5100), Niigata, Not set

Osaka International Cancer Institute ( Site 5103), Osaka, Not set

Seoul National University Hospital ( Site 3403), Seoul, Not set

Severance Hospital, Yonsei University Health System ( Site 3402), Seoul, Not set

Asan Medical Center-Division of Gynecologic Oncology, Dept. of Obstetrics & Gynecology ( Site 3401), Seoul, Not set

Samsung Medical Center ( Site 3400), Seoul, Not set

University Malaya Medical Centre ( Site 3102), Lembah Pantai, Kuala Lumpur

Sunway Medical Centre ( Site 3105), Petaling Jaya, Selangor

Pantai Hospital Kuala Lumpur ( Site 3100), Kuala Lumpur, Not set

Penang Adventist Hospital ( Site 3101), Pulau Pinang, Not set

Radboudumc-Medical Oncology ( Site 2202), Nijmegen, Gelderland

Catharina Ziekenhuis-Oncology ( Site 2203), Eindhoven, Noord-Brabant

Amsterdam UMC, locatie VUmc ( Site 2201), Amsterdam, Noord-Holland

Erasmus Medisch Centrum-Medical Oncology ( Site 2200), Rotterdam, Zuid-Holland

University Medical Center Groningen ( Site 2204), Groningen, Not set

Oslo universitetssykehus, Radiumhospitalet ( Site 2300), Oslo, Not set

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Ginekologii Onkologicznej ( Site 2400), Warszawa, Mazowieckie

Bialostockie Centrum Onkologii-Oddzial Onkologii Ginekologicznej ( Site 2402), Bialystok, Podlaskie

Uniwersytecki Szpital Kliniczny w Poznaniu-Oddzial Ginekologii Onkologicznej ( Site 2404), Poznan, Wielkopolskie

UPR Comprehensive Cancer Center-Comprehensive Cancer Center Hospital ( Site 0601), San Juan, Not set

National University Hospital ( Site 3301), Singapore, Central Singapore

National Cancer Centre Singapore ( Site 3300), Singapore, Central Singapore

HOSPITAL CLÍNIC DE BARCELONA-ICHMO- Clinic Institut of Haematological and Oncological diseases ( Site 2509), Barcelona, Cataluna

Institut Català d'Oncologia - L'Hospitalet-Medical Oncology ( Site 2508), L Hospitalet De Llobregat, Cataluna

Institut Català d'Oncologia (ICO) - Girona-Oncología Médica ( Site 2507), Girona, Gerona

Clinica Universidad de Navarra ( Site 2510), Madrid, Madrid, Comunidad De

Hospital Universitario Ramón y Cajal-Medical Oncology ( Site 2502), Madrid, Madrid, Comunidad De

Hospital Universitario 12 de Octubre-Medical Oncology ( Site 2506), Madrid, Madrid, Comunidad De

Fundación Instituto Valenciano de Oncología-Oncologico ( Site 2503), Valencia, Valenciana, Comunitat

HOSPITAL CLINICO DE VALENCIA ( Site 2505), Valencia, Valenciana, Comunitat

Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 2500), Barcelona, Not set

Hospital Universitario Reina Sofia-Oncologia Medica ( Site 2501), Cordoba, Not set

Hospital Universitario La Paz-Oncología Médica ( Site 2504), Madrid, Not set

Universitetssjukhuset i Linköping ( Site 2600), Linköping, Ostergotlands Lan

Skånes Universitetssjukhus Lund-Department of Hematology ( Site 2602), Lund, Skane Lan

Karolinska Universitetssjukhuset Solna ( Site 2601), Stockholm, Stockholms Lan

Akademiska sjukhuset ( Site 2603), Uppsala, Uppsala Lan

University Hospital Basel-Gynecology & Gynecologic Oncology ( Site 2701), Basel, Basel-Stadt

Inselspital Bern-Oncology ( Site 2700), Berne, Not set

ROYAL MARSDEN HOSPITAL (CHELSEA)-Gynaecology Research Centre ( Site 2807), London, England

Royal Marsden Hospital (Sutton)-Gynaecology Unit ( Site 2801), Sutton, England

Gartnavel General Hospital-Clinical Trials Unit ( Site 2800), Glasgow, Glasgow City

University College London Hospital ( Site 2805), London, London, City Of

St James's University Hospital ( Site 2804), Leeds, Not set

The Christie NHS Foundation Trust-Research and Development ( Site 2802), Manchester, Not set

Conditions: Cervical Cancer

Learn More ›

A Study of MK-6837 as a Monotherapy and Combination Therapy in Participants With Advanced/Metastatic Solid Tumors (MK-6837-001)

NCT06460961

Recruiting

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of MK-6837, administered as a monotherapy and in combination with pembrolizumab (MK-3475), in participants with histologically or cytologically confirmed advanced/metastatic solid tumors that have not responded to conventional therapy. There will not be any hypothesis testing in the study.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/14/2025

Locations: Atlantic Health System Morristown Medical Center ( Site 4001), Morristown, New Jersey +6 locations

Conditions: Neoplasm Metastasis

Learn More ›