All Clinical Trials in Canada

A listing of 3904 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

NCT06131840

Recruiting

This clinical trial is studying advanced solid tumors. Solid tumors are cancers that start in a part of your body like your lungs or liver instead of your blood. Once tumors have grown bigger in one place but haven't spread, they're called locally advanced. If your cancer has spread to other parts of your body, it's called metastatic. When a cancer has gotten so big it can't easily be removed or has spread to other parts of the body, it is called unresectable. These types of cancer are harder to... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/14/2025

Locations: Mayo Clinic Hospital, Phoenix, Arizona +26 locations

Mayo Clinic Hospital, Phoenix, Arizona

City of Hope, Duarte, California

University of Colorado Hospital - Anschutz Cancer Pavilion (ACP), Aurora, Colorado

University of Colorado Hospital/University of Colorado, Aurora, Colorado

Florida Cancer Specialists, Orlando, Florida

Sarah Cannon Research Institute at Florida Cancer Specialists, Orlando, Florida

Sidney Kimmel Comprehensive Cancer at Johns Hopkins, Baltimore, Maryland

Beth Israel Deaconess Medical Center, Boston, Massachusetts

START Midwest, Grand Rapids, Michigan

Mayo Clinic Cancer Center, Rochester, Minnesota

Sarah Cannon Research Institute - Pharmacy, Nashville, Tennessee

SCRI Oncology Partners, Nashville, Tennessee

The University of Texas MD Anderson Cancer Center, Houston, Texas

South Texas Accelerated Research Therapeutics, LLC, San Antonio, Texas

South Texas Accelerated Research Therapeutics Mountain Region, West Valley City, Utah

The Ottawa Hospital, Ottawa, Ontario

University Health Network, Princess Margaret Hospital, Toronto, Ontario

McGill University Health Centre, Montreal, Quebec

Institut Gustave Roussy, Villejuif Cedex, Paris

Gustave Roussy, Villejuif, Not set

Netherlands Cancer Institute, Amsterdam, Not set

Institut Catala d'Oncologia - Hospital Duran i Reynals (ICO L'Hospitalet), L'Hospitalet de Llobregat, Catalunya [cataluña]

START Madrid-CIOCC_Hospital HM Sanchinarro, Madrid, Not set

Karolinska University Hospital, Solna, Not set

ApoEx NKS, Stockholm, Not set

The University of Edinburgh, Edinburgh, Not set

Sarah Cannon Research Institute UK, London, Not set

Conditions: Colorectal Neoplasms, Carcinoma, Non-Small-Cell Lung, Stomach Neoplasms, Pancreatic Ductal Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Small Cell Lung Carcinoma

Learn More ›

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

NCT04429542

Recruiting

The investigational drug to be studied in this protocol, BCA101, is a first-in-class compound that targets both EGFR with TGFβ. Based on preclinical data, this bifunctional antibody may exert synergistic activity in patients with EGFR-driven tumors.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/14/2025

Locations: Moores Cancer Center UC San Diego Health, La Jolla, California +19 locations

Conditions: Head and Neck Squamous Cell Carcinoma, Squamous Cell Carcinoma of Anal Canal, Colorectal Cancer, Squamous Cell Carcinoma of the Lung, EGFR Amplification, Epithelial Ovarian Cancer, Pancreas Cancer, Cutaneous Squamous Cell Carcinoma, Head and Neck Neoplasms, Carcinoma, Squamous Cell, Squamous Cell Carcinoma of Head and Neck

Learn More ›

A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Disease

NCT04929210

Recruiting

The purpose of this study is to evaluate the efficacy of guselkumab treatment in participants with active psoriatic arthritis (PsA) axial disease by assessing reduction in axial symptoms and inflammation.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/14/2025

Locations: Arizona Arthritis and Rheumatology Research PLLC, Avondale, Arizona +239 locations

Arizona Arthritis and Rheumatology Research PLLC, Avondale, Arizona

Arizona Arthritis & Rheumatology Research, PLLC, Chandler, Arizona

Arizona Arthritis and Rheumatology Research PLLC, Mesa, Arizona

Arizona Arthritis Research, PLC., Phoenix, Arizona

Arizona Arthritis and Rheumatology Associates, Sun City, Arizona

Southern Arizona VA Healthcare System, Tucson, Arizona

Unity Health-White County Medical Center, Searcy, Arkansas

Kaiser Permanent Medical Center, Fontana, California

Newport Huntington Medical Group, Huntington Beach, California

University Of California San Diego, La Jolla, California

Rheumatology Center of San Diego, San Diego, California

Clinical Research Center of Connecticut, Danbury, Connecticut

Bay Pines VA Healthcare System, Bay Pines, Florida

Integral Rheumatology And Immunology Specialists, Plantation, Florida

Florida Medical Clinic, P.A., Zephyrhills, Florida

Great Lakes Clinical Trials, Chicago, Illinois

OrthoIllinois, Rockford, Illinois

Willow Rheumatology and Wellness, Willowbrook, Illinois

Johns Hopkins Bayview Medical, Baltimore, Maryland

Klein And Associates M D P A, Hagerstown, Maryland

Clinical Research Institute of Michigan, LLC, Saint Clair Shores, Michigan

St. Paul Rheumatology P A, Eagan, Minnesota

Kansas City Physician Partners, Kansas City, Missouri

Clinvest, Springfield, Missouri

STAT Research, Inc., Vandalia, Ohio

OHSU Rheumatology Clinic, Marquam Hill, Portland, Oregon

Amarillo Center for Clinical Research, Amarillo, Texas

Austin Regional Clinic, Austin, Texas

Precision Comprehensive Clinical Research Solutions, Colleyville, Texas

Adriana Pop Moody MD Clinic PA, Corpus Christi, Texas

AARA Clinical Research Lone Star Arthritis and Rheumatology, Fort Worth, Texas

UT Physicians Center for Autoimmunity, Houston, Texas

AARA Clinical Research Lone Star Arthritis and Rheumatology, Irving, Texas

West Texas Clinical Research, Lubbock, Texas

Southwest Rheumatology Research LLC, Mesquite, Texas

Epic Medical Research, Red Oak, Texas

DM Clinical Research, Tomball, Texas

Swedish Medical Center, Seattle, Washington

Cosultorios Reumatologógicos Pampa, Buenos Aires, Not set

Hospital Italiano de Buenos Aires, Buenos Aires, Not set

Centro Privado de Medicina Familiar, Buenos Aires, Not set

Hospital Italiano La Plata, La Plata, Not set

MR Medicina Reumatologica, San Fernando, Not set

Centro Medico Privado de Reumatologia, San Miguel De Tucuman, Not set

Emeritus Research, Camberwell, Not set

Southern Clinical Research, Hobart, Not set

Liverpool Hospital, Liverpool, Not set

Rheumatology Research Unit, Maroochydore, Not set

Skin Health Institute Inc., Melbourne, Not set

Eastern Health - Box Hill Hospital, Melbourne, Not set

Exacta Medica, Pleven, Not set

UMHAT 'Dr. Georgi Stranski', EAD, Pleven, Not set

Medical Center Unimed Plovdiv, Plovdiv, Not set

UMHAT Kaspela, Plovdiv, Not set

Medical Center Artmed, Plovdiv, Not set

MHAT 'Lyulin' EAD, Sofia, Not set

University Multiprofile Hospital Sofiamed Sofia, Sofia, Not set

Military Medical Academy, Sofia, Not set

UMHAT St. Ivan Rilski, Sofia, Not set

DCC Convex EOOD, Sofia, Not set

ASIMP Rheumatology Centre St Irina EOOD, Sofia, Not set

Medical Centre Synexus, Sofia, Not set

DDC Sv. Ivan Rilski OOD, Targovishte, Not set

Skin Care Centre, Vancouver, British Columbia

Eastern Regional Health Authority St Clares Mercy Hospital, St Johns, Newfoundland and Labrador

Toronto Western Hospital, Toronto, Ontario

G R M O Groupe de recherche en maladies osseuses Inc, Quebec, Not set

Revmacentrum MUDr Mostera s r o, Brno Zidenice, Not set

Revmaclinic, Brno, Not set

Revmatologie s r o, Brno, Not set

L K N Arthrocentrum, Hlucin, Not set

Revimex Pro s r o, Karvina Frystat, Not set

MUDr Rosypalova s r o, Ostrava, Not set

Arthrohelp S.R.O., Pardubice, Not set

Revmatologicky ustav, Praha, Not set

Medical Plus S R O, Uherske Hradiste, Not set

Frederiksberg Hospital, Frederiksberg, Not set

Rigshospitalet Glostrup, Glostrup, Not set

Køge Sygehus Region Sjaelland, Køge, Not set

Vejle Sygehus, Vejle, Not set

Ltd Health Center, Batumi, Not set

LTD Clinic LJ, Kutaisi, Not set

Ltd American Hospital Network, T'bilisi, Not set

Tbilisi Heart and Vascular Clinic Ltd, T'bilisi, Not set

LTD 'Aversi Clinic', T'bilisi, Not set

Clinic on Mtskheta Street, T'bilisi, Not set

Aleksandre Aladashvili Clinic LLC, Tbilisi, Not set

LTD Helsicore, Tbilisi, Not set

Ltd New Hospitals, Tbilisi, Not set

TSMU The First University Clinic, Tbilisi, Not set

JSC K Eristavi National Center of experimental and Clinical surgery, Tbilisi, Not set

LTD MediClub Georgia, Tbilisi, Not set

LTD The First Medical Center, Tbilisi, Not set

Consilium Medulla-multiprofile clinic Ltd, Tbilisi, Not set

JSC Evex Hospitals, Tnilisi, Not set

ISA - Interdisciplinary Study Association GmbH, Berlin, Not set

Hamburger Rheuma Forschungszentrum II, Hamburg, Not set

Rheumazentrum Ruhrgebiet, Herne, Not set

Rheumazentrum Ratingen, Ratingen, Not set

Prince Of Wales Hospital, Hong Kong, Not set

Betegapolo Irgalmas Rend Budai Irgalmasrendi Korhaz, Budapest, Not set

Obudai Egeszsegugyi Centrum Kft, Budapest, Not set

Qualiclinic Kft, Budapest, Not set

Bekes Varmegyei Kozponti Korhaz Pandy Kalman Tagkorhaz, Gyula, Not set

Porcika Klinika - Vasarhelyi Sarkanyfu Kft., Hodmezovasarhely, Not set

Kistarcsai Flor Ferenc Korhaz, Kistarcsa, Not set

Fejer Varmegyei Szent Gyorgy Egyetemi Oktatokorhaz, Székesfehérvár, Not set

Vital Medical Center Orvosi es Fogaszati Kozpont, Veszprem, Not set

Bnai Zion Medical Center, Haifa, Not set

Carmel Medical Center, Hifa, Not set

Wolfson Medical Center, Holon, Not set

Meir Medical Center, Kfar-Sava, Not set

Sheba Medical Center, Ramat Gan, Not set

A.O. Universitaria Ospedali Riuniti di Ancona, Ancona, Not set

Azienda Ospedaliero-Universitaria di Cagliari, Monserrato, Not set

Arcispedale Santa Maria Nuova - IRCCS, Reggio Emilia, Not set

Policlinico Tor Vergata, Roma, Not set

Humanitas Hospital, Rozzano (MI), Not set

Azienda Ospedaliera Universitaria Integrata Verona, Verona, Not set

Hospital Selayang, Batu Caves, Not set

Hospital Pulau Pinang, George Town, Not set

Hospital Sultan Ismail, Johor Bahru, Not set

University Malaya Medical Centre, Kuala Lumpur, Not set

Hospital Tuanku Jaafar, Seremban, Not set

Cebu Doctors' University Hospital, Cebu City, Not set

Davao Doctors Hospital, Davao City, Not set

Lipa Medix Medical Hospital, Lipa, Not set

ManilaMed Medical Center Manila, Manila, Not set

Philippine General Hospital, Manila, Not set

St. Luke's Medical Center, Quezon City, Not set

Ilocos Training and Regional Medical Center, San Fernando, Not set

ClinicMed Daniluk Nowak Spolka Komandytowa, Bialystok, Not set

Szpital Uniwersytecki nr 2 im dr Jana Biziela, Bydgoszcz, Not set

Nzoz Bif Med, Bytom, Not set

Centrum Kliniczno Badawcze, Elblag, Not set

Ambulatorium sp. z o.o., Elblag, Not set

Malopolskie Badania Kliniczne Sp z o o, Krakow, Not set

Centrum Medyczne Promed, Krakow, Not set

Dermed Centrum Medyczne Sp z o o, Lodz, Not set

Centrum Terapii Wspolczesnej J M Jasnorzewska Spolka Komandytowo Akcyjna, Lodz, Not set

Centrum Medyczne AMED oddzial w Lodzi, Lodz, Not set

Velocity Lublin, Lublin, Not set

Reumed Zespol Poradni Specjalistycznych Filia nr 1, Lublin, Not set

Pro Life Medica Sp. z o.o., Lublin, Not set

NZOZ Lecznica MAK MED S C, Nadarzyn, Not set

Twoja Przychodnia - Centrum Medyczne Nowa Sol, Nowa Sol, Not set

Twoja Przychodnia PCM, Poznan, Not set

Reumedika s c Wieslawa Porawska Lukasz Porawski, Poznan, Not set

Lubelskie Centrum Diagnostyczne, Swidnik, Not set

MICS Centrum Medyczne Torun, Torun, Not set

MICS Centrum Medyczne Warszawa, Warsaw, Not set

Narodowy Instytut Geriatrii Reumatologii i Rehabilitacji im prof dr hab med Eleonory Reicher, Warsaw, Not set

Rheuma Medicus Sp z o o, Warszawa, Not set

Centrum Medyczne Reuma Park, Warszawa, Not set

ETG Warszawa, Warszawa, Not set

Centrum Medyczne AMED Targowek, Warszawa, Not set

WroMedica I Bielicka A Strzalkowska s c, Wroclaw, Not set

Uls Braga - Hosp. Braga, Braga, Not set

Ulsg - Hosp. Sousa Martins, Guarda, Not set

Ipr Inst Port de Reumatologia, Lisboa, Not set

Uls Lisboa Ocidental - Hosp. Egas Moniz, Lisboa, Not set

Hosp. Cuf Tejo, Lisboa, Not set

Uls Santa Maria - Hosp. Santa Maria, Lisboa, Not set

Ulsam - Hosp. Conde de Bertiandos, Ponte de Lima, Not set

Uls Sao Joao - Hosp. Sao Joao, Porto, Not set

Altay Medical State University, Barnaul, Not set

Chelyabinck Regional Clinical Hospital, Chelyabinsk, Not set

Chelyabinsk Regional Clinical Dermatovenerological Dispensary, Chelyabinsk, Not set

Sverdlovsk Regional Clinical Hospital N. 1, Ekaterinbourg, Not set

Regional Clinical Diagnostic Center of Udmurtia Region, Izhevsk, Not set

LLL Medical Center Revma-Med, Kemerovo, Not set

LLC Family Outpatient Clinic # 4, Korolev, Not set

Regional SBI of PH Krasnoyarsk Regional Clinical hospital #20 named after I.S. Berzon, Krasnoyarsk, Not set

Clinical-Diagnostic Center Euromedservice, JSC, Moscow, Not set

FGBU Research Institute of Rheumatology named V.A.Nasonova, Moscow, Not set

GBUZ of Moscow Region 'Moscow Region SRI n.a. Vladimirskyi', Moscow, Not set

Llc Ultramed, Omsk, Not set

GBOU VPO Orenburg State Medical University, Orenburg, Not set

GBUZ Perm Regional Clinical Hospital, Perm, Not set

Republican Hospital n.a.V.A.Baranov, Petrozavodsk, Not set

Rostov Regional Clinical Dermatovenerological Dispensary, Rostov, Not set

St. Petersburg GBUZ Clinical Reumatological Hospital 25, St. Petersburg, Not set

X7 Clinical Research Company Limited, St. Petersburg, Not set

GBUZ of Samara Region 'Tolyatti City Clinical Hospital 5', Tolyatti, Not set

Republican Clinical Hospital - G.G. Kuvatov, Ufa, Not set

Clinical Hospital #3, Yaroslavl, Not set

Reumatologicka ambulancia, Martin, Not set

Reumatologicka ambulancia, Nove Mesto nad Vahom, Not set

Reumatologická ambulancia Thermium s.r.o., Piestany, Not set

REUMAMED POPRAD, s.r.o., Poprad, Not set

Reumex s.r.o, Rimavska Sobota, Not set

Hosp Univ A Coruna, A Coruna, Not set

Hosp. Univ. de Cruces, Barakaldo, Not set

Hosp Clinic de Barcelona, Barcelona, Not set

Hosp. Univ. de Basurto, Bilbao, Not set

Hosp Reina Sofia, Cordoba, Not set

Hosp. Clinico San Carlos, Madrid, Not set

Hosp Regional Univ de Malaga, Málaga, Not set

Corporacio Sanitari Parc Tauli, Sabadell, Not set

Clinica Gaias, Santiago de Compostela, Not set

Hosp. Virgen Macarena, Sevilla, Not set

Hosp. Quiron Sagrado Corazon, Sevilla, Not set

Hosp. Univ. I Politecni La Fe, Valencia, Not set

Karolinska Universitetssjukhuset, Solna, Not set

Akademiska Sjukhuset, Uppsala, Not set

National Taiwan University Hospital, Hsin Chu, Not set

National Cheng Kung University Hospital, Tainan, Not set

Linkou Chang Gung Memorial Hospital, Taoyuan, Not set

Phramongkutklao Hospital and Medical College, Bangkok, Not set

Ramathibodi Hospital Mahidol University, Bangkok, Not set

Chiang Mai University, Chiangmai, Not set

Adana City Hospital, Adana, Not set

Gulhane Training and Research Hospital, Ankara, Not set

Ankara Bilkent City Hospital, Ankara, Not set

Hacettepe University Medical Faculty, Ankara, Not set

Akdeniz University Medical Faculty, Antalya, Not set

Uludag University Medical Faculty, Bursa, Not set

Istanbul University Cerrahpasa Medical Faculty, Istanbul, Not set

Marmara University Medical Faculty, Istanbul, Not set

Necmettin Erbakan University Meram Medical Faculty, Konya, Not set

Communal Noncommercial Enterprise Cherkasy Regional Hospital of Cherkasy Regional Council, Cherkasy, Not set

Municipal non-commercial enterprise of Kharkiv Regional Council Regional Clinical Hospital, Kharkiv, Not set

Khmelnitckiy regional hospital, Khmelnytsky, Not set

City Clinical Hospital No. 2, Kryvyi Rih, Not set

Medical Center of 'Institute of Rheumatology', LLC, Kyiv, Not set

Kyiv Railway Clinical Hospital #2 Of Branch 'Health Center' Of The Company 'Ukrainian Railway', Kyiv, Not set

SI National Scientific Center Institute of Cardiology of M.D. Strazhesko of NAMS of Ukraine, Kyiv, Not set

Volyn Regional Clinical Hospital, Lutsk, Not set

Municipal Non-profit Enterprise 'Odesa Regional Clinical Hospital' Odesa Regional Council, Odessa, Not set

ME Poltava Regional Clinical Hospital named after M.V. Sklifosovsky of Poltava Regional Consuil, Poltava, Not set

Municipal institution of Tepnopil Regional Council 'Ternopil University Hospital', Ternopil, Not set

Health Clinic Limited Liability Company, Vinnytsia, Not set

Medical Center LLC 'Modern Clinic', Zaporizhzhya, Not set

Royal Free London NHS Foundation Trust, Barnet, Not set

St. Lukes Hospital, Bradford, Not set

University Hospital Coventry & Warwickshire NHS Trust, Coventry, Not set

Chapel Allerton Hospital, Leeds, Not set

Central Manchester University Hospitals NHS Foundation Trust, Manchester, Not set

North Tyneside General Hospital, Newcastle, Not set

Haywood Hospital, Stoke on Trent, Not set

Conditions: Arthritis, Psoriatic

Learn More ›

Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

NCT06122779

Recruiting

The purpose of this study is to evaluate the safety, tolerability, and exposure-response (E-R) of BMS-986435/MYK-224 in participants with symptomatic Heart Failure with Preserved Ejection Fraction (HFpEF).

Gender:

ALL

Ages:

Between 40 years and 85 years

Trial Updated:

08/14/2025

Locations: University of Alabama at Birmingham, Birmingham, Alabama +115 locations

University of Alabama at Birmingham, Birmingham, Alabama

Colorado Heart and Vascular - Lakewood, Lakewood, Colorado

Ascension St. Vincent's Riverside Hospital, Jacksonville, Florida

Local Institution - 0003, Miami, Florida

Local Institution - 0099, Miami, Florida

Local Institution - 0014, Atlanta, Georgia

Local Institution - 0048, Atlanta, Georgia

Bluhm Cardiovascular Institute of Northwestern, Chicago, Illinois

Chicago Medical Research, LLC, Hazel Crest, Illinois

Ascension Medical Group St. Vincent - Indianapolis Heart Care, Indianapolis, Indiana

Local Institution - 0045, Indianapolis, Indiana

St. Louis Heart and Vascular, Saint Louis, Missouri

Local Institution - 0043, Saint Louis, Missouri

Capital Cardiology Associates, Albany, New York

Local Institution - 0105, Brooklyn, New York

Weill Cornell Medicine, New York, New York

Local Institution - 0059, Rochester, New York

Local Institution - 0076, Rochester, New York

Local Institution - 0094, Rosedale, New York

Local Institution - 0095, Durham, North Carolina

Local Institution - 0058, Cincinnati, Ohio

Local Institution - 0041, Oklahoma City, Oklahoma

South Oklahoma Heart Research, Oklahoma City, Oklahoma

Local Institution - 0078, Abington, Pennsylvania

Tennessee Center for Clinical Trials, Tullahoma, Tennessee

Local Institution - 0104, Austin, Texas

University of Texas Southwestern Medical Center, Dallas, Texas

Angiocardiac Care of Texas - PA - PPDS, Houston, Texas

Local Institution - 0051, Houston, Texas

Local Institution - 0066, Falls Church, Virginia

Local Institution - 0054, General San Martín, Buenos Aires

Local Institution - 0107, Zárate, Buenos Aires

Local Institution - 0115, Zárate, Buenos Aires

Local Institution - 0090, Córdoba, Cordoba

Local Institution - 0053, Córdoba, Cordoba

Local Institution - 0073, Rosario, Santa FE

Local Institution - 0061, San Miguel De Tucumán, Tucuman

Local Institution - 0060, Ciudad Autonoma de Buenos Aires, Not set

Local Institution - 0067, Ciudad Autonoma de Buenos Aires, Not set

Local Institution - 0068, Ciudad Autónoma de Buenos Aires, Not set

Local Institution - 0074, Córdoba, Not set

Local Institution - 0069, Salta, Not set

Local Institution - 0102, Santa Fe, Not set

Hamilton General Hospital, Hamilton, Ontario

Medicus MFC Inc., Toronto, Ontario

Local Institution - 0030, Toronto, Ontario

Local Institution - 0040, Toronto, Ontario

Local Institution - 0011, Montreal, Quebec

Local Institution - 0035, Trois-Rivieres, Quebec

Peking Union Medical College Hospital - East Campus, Beijing, Beijing

Local Institution - 0087, Guangzhou, Guangdong

Local Institution - 0080, Luoyang, Henan

Local Institution - 0079, Changsha, Hunan

The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang

Local Institution - 0109, Jerusalem, Yerushalayim

Local Institution - 0113, Jerusalem, Yerushalayim

Local Institution - 0112, Be'er - Ya'akov, Not set

Local Institution - 0111, Be'er Sheva, Not set

Local Institution - 0108, Haifa, Not set

Local Institution - 0110, Petah Tikva, Not set

Local Institution - 0106, Rehovot, Not set

Local Institution - 0116, Safed, Not set

Local Institution - 0019, Napoli, Campania

Local Institution - 0023, Milano, Lombardia

Local Institution - 0033, Milano, Lombardia

IRCCS Policlinico San Donato, San Donato Milanese, Lombardia

Local Institution - 0050, San Donato Milanese, Lombardia

Local Institution - 0027, Foggia, Puglia

Local Institution - 0038, Foggia, Puglia

Local Institution - 0052, Massa, Toscana

Local Institution - 0009, Bergamo, Not set

Local Institution - 0017, Pisa, Not set

Hyogo Prefectural Harima-Himeji General Medical Center, Himeji-Shi, Hyogo

National Hospital Organization Kanazawa Medical Center, Kanazawa, Ishikawa

Okayama Rosai Hospital, Okayama-Shi, Okayama

Kishiwada Tokushukai Hospital, Kishiwada, Osaka

Takatsuki Red Cross Hospital, Takatsuki-Shi, Osaka

Local Institution - 0088, Daegu, Daegu Gwang'yeogsi

Local Institution - 0084, Daejeon, Daejeon Gwang'yeogsi

Local Institution - 0083, Gwangju, Gwangju Gwang'yeogsi

Inha University Hospital, Jung-gu, Incheon Gwang'yeogsi

Local Institution - 0085, Seoul, Seoul Teugbyeolsi

Local Institution - 0114, Seoul, Seoul Teugbyeolsi

Local Institution - 0055, Seoul, Seoul Teugbyeolsi

Local Institution - 0086, Busan, Not set

Local Institution - 0098, Seongnam-si, Not set

Local Institution - 0081, Seoul, Not set

Clinical Trials UMED Sp. z o.o., Lódz, Lódzkie

Local Institution - 0031, Bialystok, Podlaskie

Local Institution - 0044, Bialystok, Podlaskie

Local Institution - 0020, Lublin, Woj. Lubelskie

Local Institution - 0049, Lublin, Woj. Lubelskie

Local Institution - 0006, Krakow, Not set

Local Institution - 0024, Oswiecim, Not set

Local Institution - 0012, Hospitalet de Llobregat, Barcelona

Local Institution - 0025, Majadahonda, Madrid

Local Institution - 0047, Majadahonda, Madrid

Hospital Universitario Virgen de La Arrixaca, El Palmar, Murcia

Local Institution - 0039, El Palmar, Murcia

Local Institution - 0042, Malaga, Málaga

Local Institution - 0026, Madrid, Not set

Local Institution - 0034, Madrid, Not set

Local Institution - 0032, Malaga, Not set

Hospital Nuestra Señora de Valme, Sevilla, Not set

Local Institution - 0046, Sevilla, Not set

Local Institution - 0010, Valencia, Not set

Local Institution - 0063, Harrow, Greater London

Local Institution - 0071, North Shields, Northumberland

Local Institution - 0062, Oxford, Oxfordshire

Local Institution - 0072, Leeds, Yorkshire

Local Institution - 0057, Sheffield, Yorkshire

Local Institution - 0101, Bristol, Not set

Local Institution - 0097, Dundee, Not set

Local Institution - 0075, London, Not set

Local Institution - 0065, Stockton-On-Tees, Not set

Local Institution - 0064, Wolverhampton, Not set

Conditions: Heart Failure

Learn More ›

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

NCT05156281

Recruiting

To compare the efficacy and safety of remibrutinib versus teriflunomide in patients with relapsing multiple sclerosis (RMS)

Gender:

ALL

Ages:

Between 18 years and 55 years

Trial Updated:

08/14/2025

Locations: Ctr for Neurology and Spine, Phoenix, Arizona +240 locations

Ctr for Neurology and Spine, Phoenix, Arizona

Vladimir Royter MD APMC, Hanford, California

VA Greater LA Healthcare System, Los Angeles, California

Regina Berkovich MD PhD Inc, West Hollywood, California

CU Anschutz Med Campus, Aurora, Colorado

Colorado Springs Neurological Associates, Colorado Springs, Colorado

Colorado Neurological Research PC, Denver, Colorado

New England Institute for Clinical Research, Stamford, Connecticut

Georgetown University Hospital Research, Washington, District of Columbia

Georgetown University Hospital, Washington, District of Columbia

SFM Clinical Research LLC, Boca Raton, Florida

Nova Clinical Research LLC, Bradenton, Florida

University of Florida, Gainesville, Florida

Memorial Healthcare System, Hollywood, Florida

Mayo Clinic Jacksonville, Jacksonville, Florida

Neurology Associates PA, Maitland, Florida

Gables Neurology, Miami, Florida

UM Department Of Neurology, Miami, Florida

Aqualane Clinical Research, Naples, Florida

Advent Health Orlando, Orlando, Florida

Humanity Clinical Research, Pembroke Pines, Florida

Emerald Coast Neurology, Pensacola, Florida

Brain and Spine Institute, Port Orange, Florida

Vero Beach Neurology, Vero Beach, Florida

Conquest Research, Winter Park, Florida

Georgia Neurology and Sleep Medicine Assoc, Suwanee, Georgia

Methodist Neuroscience Institute, Merrillville, Indiana

University of Kansas Hospital, Kansas City, Kansas

Baptist Physicians Lexington, Nicholasville, Kentucky

Ochsner Clinic Foundation, New Orleans, Louisiana

Comprehensive Neurology, Frederick, Maryland

Tufts Medical Center, Boston, Massachusetts

Memorial Healthcare, Owosso, Michigan

Kansas City VA Medical Center, Kansas City, Missouri

South Shore Neurologic Associates, Patchogue, New York

True North Neurology, Port Jefferson Station, New York

University Of NC At Chapel Hill, Chapel Hill, North Carolina

Piedmont HealthCare, Charlotte, North Carolina

The Boster Ctr for MS, Columbus, Ohio

Neurology Diagnostics Inc, Dayton, Ohio

Penn State Hershey Medical Center, Hershey, Pennsylvania

Medical Uni of South Carolina, Charleston, South Carolina

Premier Neurology, Greenville, South Carolina

Metrolina Neurological Associates PA, Indian Land, South Carolina

Sibyl Wray MD Neurology PC, Knoxville, Tennessee

Neurology Consultants Of Dallas PA, Dallas, Texas

Med Research Inc, El Paso, Texas

Lone Star Neurology, Frisco, Texas

Neurocare Plus, Houston, Texas

UT Health MARC Medical Arts and Research Center, San Antonio, Texas

Lonestar Neurology of San Antonio, San Antonio, Texas

Texas Institute for Neurological Disorders, Sherman, Texas

Baylor Scott and White, Temple, Texas

Virginia Mason Medical Centre, Seattle, Washington

University of Washington MS Clinic, Seattle, Washington

Elligo Health Research, Crab Orchard, West Virginia

Aurora BayCare Medical Center, Green Bay, Wisconsin

Ascension St Francis Center, Milwaukee, Wisconsin

Medical College of Wisconsin, Milwaukee, Wisconsin

Novartis Investigative Site, Caba, Buenos Aires

Novartis Investigative Site, Bombal, Mendoza

Novartis Investigative Site, Rosario, Santa Fe

Novartis Investigative Site, San Miguel De, Tucuman

Novartis Investigative Site, Buenos Aires, Not set

Novartis Investigative Site, Cordoba, Not set

Novartis Investigative Site, Brasilia, DF

Novartis Investigative Site, Vitoria, ES

Novartis Investigative Site, Curitiba, PR

Novartis Investigative Site, Porto Alegre, Rio Grande Do Sul

Novartis Investigative Site, Porto Alegre, RS

Novartis Investigative Site, Joinville, Santa Catarina

Novartis Investigative Site, Sao Paulo, Not set

Novartis Investigative Site, Plovdiv, Not set

Novartis Investigative Site, Sofia, Not set

Novartis Investigative Site, Edmonton, Alberta

Novartis Investigative Site, Burnaby, British Columbia

Novartis Investigative Site, Halifax, Nova Scotia

Novartis Investigative Site, Ottawa, Ontario

Novartis Investigative Site, Greenfield Park, Quebec

Novartis Investigative Site, Levis, Quebec

Novartis Investigative Site, Montreal, Quebec

Novartis Investigative Site, St Jerome, Quebec

Novartis Investigative Site, Quebec, Not set

Novartis Investigative Site, Fuzhou, Fujian

Novartis Investigative Site, Wuhan, Hubei

Novartis Investigative Site, Nanjing, Jiangsu

Novartis Investigative Site, Yinchuan, Ningxia

Novartis Investigative Site, Taiyuan, Shanxi

Novartis Investigative Site, Hangzhou, Zhejiang

Novartis Investigative Site, Wenzhou, Zhejiang

Novartis Investigative Site, Beijing, Not set

Novartis Investigative Site, Shanghai, Not set

Novartis Investigative Site, Split, HRV

Novartis Investigative Site, Varazdin, HRV

Novartis Investigative Site, Vukovar, Not set

Novartis Investigative Site, Zagreb, Not set

Novartis Investigative Site, Tallinn, Not set

Novartis Investigative Site, Tartu, Not set

Novartis Investigative Site, Limoges, Haute Vienne

Novartis Investigative Site, Toulon Cedex 9, Val De Marne

Novartis Investigative Site, Caen, Not set

Novartis Investigative Site, Clermont-Ferrand Cedex 1, Not set

Novartis Investigative Site, Contamine Sur Arve, Not set

Novartis Investigative Site, Dijon, Not set

Novartis Investigative Site, Gonesse, Not set

Novartis Investigative Site, Grenoble, Not set

Novartis Investigative Site, Lille, Not set

Novartis Investigative Site, Marseille, Not set

Novartis Investigative Site, Nantes Cedex 1, Not set

Novartis Investigative Site, Nice, Not set

Novartis Investigative Site, Nimes, Not set

Novartis Investigative Site, Poissy, Not set

Novartis Investigative Site, Suresnes, Not set

Novartis Investigative Site, Toulouse, Not set

Novartis Investigative Site, Chaidari, Attiki

Novartis Investigative Site, Ioannina, GR

Novartis Investigative Site, Larissa, GR

Novartis Investigative Site, Athens, Not set

Novartis Investigative Site, Greece, Not set

Novartis Investigative Site, Thessaloniki, Not set

Novartis Investigative Site, New Delhi, Delhi

Novartis Investigative Site, Kochi, Kerala

Novartis Investigative Site, Pune, Maharashtra

Novartis Investigative Site, Amritsar, Punjab

Novartis Investigative Site, Hyderabad, Telangana

Novartis Investigative Site, Lucknow, Uttar Pradesh

Novartis Investigative Site, Kolkata, West Bengal

Novartis Investigative Site, Brindisi, BR

Novartis Investigative Site, Foggia, FG

Novartis Investigative Site, Firenze, FI

Novartis Investigative Site, Pozzilli, IS

Novartis Investigative Site, Messina, ME

Novartis Investigative Site, Baggiovara, MO

Novartis Investigative Site, Pavia, PV

Novartis Investigative Site, Orbassano, TO

Novartis Investigative Site, Napoli, Not set

Novartis Investigative Site, Nagoya, Aichi

Novartis Investigative Site, Ichihara, Chiba

Novartis Investigative Site, Fukuoka city, Fukuoka

Novartis Investigative Site, Koriyama city, Fukushima

Novartis Investigative Site, Sapporo city, Hokkaido

Novartis Investigative Site, Nishinomiya, Hyogo

Novartis Investigative Site, Isehara, Kanagawa

Novartis Investigative Site, Sagamihara, Kanagawa

Novartis Investigative Site, Sendai city, Miyagi

Novartis Investigative Site, Kashihara city, Nara

Novartis Investigative Site, Moriguchi, Osaka

Novartis Investigative Site, Suita, Osaka

Novartis Investigative Site, Higashimatsuyama, Saitama

Novartis Investigative Site, Itabashi-ku, Tokyo

Novartis Investigative Site, Kodaira, Tokyo

Novartis Investigative Site, Shinjuku Ku, Tokyo

Novartis Investigative Site, Shinjuku ku, Tokyo

Novartis Investigative Site, Shinjuku-ku, Tokyo

Novartis Investigative Site, Chiba, Not set

Novartis Investigative Site, Fukuoka, Not set

Novartis Investigative Site, Kobe shi, Not set

Novartis Investigative Site, Kyoto, Not set

Novartis Investigative Site, Niigata, Not set

Novartis Investigative Site, Ciudad de Mexico, Distrito Federal

Novartis Investigative Site, Chihuahua, Not set

Novartis Investigative Site, Ciudad De Mexico, Not set

Novartis Investigative Site, Queretaro, Not set

Novartis Investigative Site, Plewiska, Poznan

Novartis Investigative Site, Bialystok, Not set

Novartis Investigative Site, Glogow, Not set

Novartis Investigative Site, Katowice, Not set

Novartis Investigative Site, Krakow, Not set

Novartis Investigative Site, Wroclaw, Not set

Novartis Investigative Site, Zabrze, Not set

Novartis Investigative Site, Braga, Not set

Novartis Investigative Site, Coimbra, Not set

Novartis Investigative Site, Leiria, Not set

Novartis Investigative Site, Lisboa, Not set

Novartis Investigative Site, Matosinhos, Not set

Novartis Investigative Site, Santa Maria da Feira, Not set

Caribbean Center for Clinical Research, Inc, Guaynabo, Not set

Novartis Investigative Site, Targu Mures, Mures

Novartis Investigative Site, Brasov, ROM

Novartis Investigative Site, Constanta, ROM

Novartis Investigative Site, Bucharest, Not set

Novartis Investigative Site, Campulung Muscel, Not set

Novartis Investigative Site, Constanta, Not set

Novartis Investigative Site, Suceava, Not set

Novartis Investigative Site, Banska Bystrica, Not set

Novartis Investigative Site, Bratislava, Not set

Novartis Investigative Site, Celje, Not set

Novartis Investigative Site, Ljubljana, Not set

Novartis Investigative Site, Maribor, Not set

Novartis Investigative Site, Bloemfontein, Free State

Novartis Investigative Site, Pretoria, Not set

Novartis Investigative Site, Rosebank, Not set

Novartis Investigative Site, Sevilla, Andalucia

Novartis Investigative Site, Vitoria Gasteiz, Araba

Novartis Investigative Site, Gijon, Asturias

Novartis Investigative Site, Hospitalet de Llobregat, Barcelona

Novartis Investigative Site, Albacete, Castilla La Mancha

Novartis Investigative Site, Badalona, Catalunya

Novartis Investigative Site, Barcelona, Catalunya

Novartis Investigative Site, Valencia, Comunidad Valenciana

Novartis Investigative Site, Santiago De Compostela, Galicia

Novartis Investigative Site, Logrono, La Rioja

Novartis Investigative Site, Pozuelo de Alarcon, Madrid

Novartis Investigative Site, Torrejon de Ardoz, Madrid

Novartis Investigative Site, Barcelona, Not set

Novartis Investigative Site, Lleida, Not set

Novartis Investigative Site, Madrid, Not set

Novartis Investigative Site, Malaga, Not set

Novartis Investigative Site, Valencia, Not set

Novartis Investigative Site, Stockholm, Not set

Novartis Investigative Site, Sancaktepe, Istanbul

Novartis Investigative Site, Istanbul, TUR

Novartis Investigative Site, Bursa, Not set

Novartis Investigative Site, Istanbul, Not set

Novartis Investigative Site, Izmir, Not set

Novartis Investigative Site, Kayseri, Not set

Novartis Investigative Site, Kocaeli, Not set

Novartis Investigative Site, Meram, Not set

Novartis Investigative Site, Pendik Istanbul, Not set

Novartis Investigative Site, Samsun, Not set

Novartis Investigative Site, Inverness, Invernesshire

Novartis Investigative Site, Canterbury, Kent

Novartis Investigative Site, London, Not set

Conditions: Relapsing Multiple Sclerosis

Learn More ›

A Study to Evaluate the Drug Levels, Efficacy and Safety of Deucravacitinib in Pediatric Participants With Moderate to Severe Plaque Psoriasis

NCT04772079

Recruiting

The purpose of this pediatric study is to evaluate the drug levels, efficacy and safety of Deucravacitinib in pediatric participants aged 4 to \<18 years with moderate to severe plaque psoriasis. This study includes two cohorts; Cohort 1 (age 12 to \<18 years) and Cohort 2 (age 4 to \<12 years), with two parts; for each cohort. Part A will evaluate the drug levels of BMS-986165 to enable selection of 2 dose levels to be studied in Part B. Part B will assess the efficacy and safety of two dose le... Read More

Gender:

ALL

Ages:

Between 4 years and 18 years

Trial Updated:

08/14/2025

Locations: Instituto de Neumonologia Y Dermatologia, Ciudad Autonoma de Buenos Aires, Buenos Aires +62 locations

Instituto de Neumonologia Y Dermatologia, Ciudad Autonoma de Buenos Aires, Buenos Aires

Psoriahue, Ciudad Autonoma de Buenos Aires, Buenos Aires

CONEXA Investigacion Clinica S.A., Buenos Aires, Not set

Hospital Italiano de Buenos Aires, Caba, Not set

Centro de Investigaciones Metabólicas (CINME), Ciudad Autónoma de Buenos Aires, Not set

Consultora Integral de Salud, Córdoba, Not set

The Skin Hospital, Darlinghurst, New South Wales

Local Institution - 0002, Westmead, New South Wales

Queensland Children's Hospital, Brisbane, Queensland

Veracity Clinical Research, Woolloongabba, Queensland

Monash Health, Clayton, Victoria

Local Institution - 0001, Melbourne, Victoria

Centro de Pesquisas da Clínica IBIS, Salvador, Bahia

Hospital Moinhos de Vento, Porto Alegre, Rio Grande Do Sul

Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (USP) - HCFMRP, Ribeirão Preto, São Paulo

Local Institution - 0083, Rio de Janeiro, Not set

Local Institution - 0067, São Paulo, Not set

Local Institution - 0010, Calgary, Alberta

Alberta Dermasurgery Centre, Edmonton, Alberta

Local Institution - 0039, Hamilton, Ontario

Lynderm Research Inc., Markham, Ontario

The Hospital for Sick Children, Toronto, Ontario

Local Institution - 0090, Calais, Not set

Centre Hospitalier Universitaire Dijon Bourgogne - Hôpital François Mitterrand-dermatology, Dijon, Not set

Centre Hospitalier Universitaire de Nice - Hôpital l'Archet, Nice, Not set

Local Institution - 0021, Paris, Not set

Universitätsklinikum Münster, Münster, Nordrhein-Westfalen

Universitätsmedizin Johannes Gutenberg Universität Mainz, Mainz, Rheinland-Pfalz

Universitaetsklinikum Carl Gustav Carus Dresden, Dresden, Sachsen

Charité Universitaetsmedizin Berlin - Campus Mitte, Berlin, Not set

Kath. Kinderkrankenhaus Wilhelmstift, Hamburg, Not set

Nagoya City University Hospital, Nagoya, Aichi

Fukuoka University Hospital, Fukuoka, Jonan-Ku, Fukuoka

Local Institution - 0040, Isehara, Kanagawa

Mie University Hospital, Tsu, Mie

Teikyo University Hospital, Itabashi-ku, Tokyo

Tokyo Medical University Hospital, Shinjuku-ku, Tokyo

Nippon Life Hospital, Osaka, Not set

Local Institution - 0048, Seoul, Seoul-teukbyeolsi [Seoul]

Local Institution - 0047, Seoul, Seoul-teukbyeolsi [Seoul]

The Catholic Univ. of Korea Seoul St. Mary's Hospital, Seoul, Seoul-teukbyeolsi [Seoul]

RM Pharma Specialists, Mexico City, Distrito Federal

Crea de Guadalajara, Guadalajara, Jalisco

Grupo Clínico CATEI S.C., Guadalajara, Jalisco

Arké SMO S.A de C.V, Veracruz, Not set

Local Institution - 0011, Krakow, Not set

Dermoklinika Centrum Medyczne S.C. M. Kierstan, J. Narbutt, A. Lesiak, Lodz, Not set

Państwowy Instytut Medyczny MSWiA-Klinika Dermatologii, Warsaw, Not set

WroMedica, Wroclaw, Not set

Local Institution - 0080, Bucharest, București

Lotus-Med Tunari, Bucharest, București

Local Institution - 0088, Bucharest, București

Local Institution - 0081, Bucuresti, București

CCBR Clinical Research, Bucuresti, București

Spitalul clinic de urgenta pentru copii Sf. Maria, Iasi, Not set

Spitalul Clinic Judetean Mures, Targu Mures, Not set

Hospital General Universitario de Alicante-Dermatology, Alicante, Not set

OSI Ezkerraldea-Enkarterri-Cruces - Hospital Universitario Cruces-Dermatology, Barakaldo, Not set

Hospital Sant Joan de Déu-URC Dermatology, Esplugues de Llobregat, Not set

Hospital Universitario de Gran Canaria Doctor Negrín-Dermatología, Las Palmas De GC, Not set

Hospital Universitario 12 de Octubre-DERMATOLOGY, Madrid, Not set

Hospital Universitario La Paz-UCICEC/DERMA, Madrid, Not set

Mounts Bay Medical, Connor Downs, Not set

Conditions: Plaque Psoriasis

Learn More ›

Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma

NCT05489887

Recruiting

This is a prospective, multicenter clinical trial in subjects with newly diagnosed high-risk neuroblastoma to evaluate the efficacy and safety of administering naxitamab with standard induction therapy. The initial chemotherapy will include 5 cycles of multi-agent chemotherapy. Naxitamab will be added to all 5 Induction cycles. We hypothesize that the addition of anti-GD2 therapy to induction chemotherapy will result in improved end of induction responses and improved survival.

Gender:

ALL

Ages:

Between 12 months and 21 years

Trial Updated:

08/14/2025

Locations: University of Alabama, Children's Alabama, Birmingham, Alabama +22 locations

Conditions: High-risk Neuroblastoma

Learn More ›

Sacituzumab Tirumotecan (MK-2870) in Post Platinum and Post Immunotherapy Endometrial Cancer (MK-2870-005)

NCT06132958

Recruiting

Researchers are looking for new ways to treat people with endometrial cancer (EC) who have previously received treatment with platinum based therapy (a type of chemotherapy) and immunotherapy. Immunotherapy is a treatment that helps the immune system fight cancer. This clinical study will compare sacituzumab tirumotecan to chemotherapy. The goal of the study is to learn if people who receive sacituzumab tirumotecan live longer overall and without the cancer getting worse compared to people who r... Read More

Gender:

FEMALE

Ages:

18 years and above

Trial Updated:

08/14/2025

Locations: USA Mitchell Cancer Institute ( Site 4142), Mobile, Alabama +241 locations

USA Mitchell Cancer Institute ( Site 4142), Mobile, Alabama

Alaska Womens Cancer Care ( Site 4122), Anchorage, Alaska

HonorHealth (HH) ( Site 8000), Phoenix, Arizona

Arizona Oncology Associates - HOPE ( Site 8002), Tucson, Arizona

UCLA Hematology/Oncology - Westwood (Building 100)-Department of OBGYN, Division of Gynecologic Onc ( Site 4131), Los Angeles, California

California Pacific Medical Center - Van Ness Campus ( Site 4129), San Francisco, California

Yale-New Haven Hospital-Smilow Cancer Hospital at Yale-New Haven ( Site 4114), New Haven, Connecticut

MedStar Washington Hospital Center ( Site 4108), Washington, District of Columbia

Mount Sinai Cancer Center ( Site 4117), Miami Beach, Florida

AdventHealth Orlando-AdventHealth Medical Group Gynecological Oncology ( Site 4113), Orlando, Florida

Florida Cancer Specialists - East ( Site 7000), West Palm Beach, Florida

Northside Hospital ( Site 4112), Atlanta, Georgia

Augusta University ( Site 4116), Augusta, Georgia

Centricity Research Columbus Cancer Center ( Site 4154), Columbus, Georgia

NorthShore University HealthSystem - Evanston Hospital ( Site 4110), Evanston, Illinois

Parkview Research Center at Parkview Regional Medical Center ( Site 4132), Fort Wayne, Indiana

Saint Elizabeth Medical Center Edgewood-Cancer Care Center ( Site 4150), Edgewood, Kentucky

University Medical Center New Orleans ( Site 4133), New Orleans, Louisiana

TRIALS 365 ( Site 4105), Shreveport, Louisiana

University of Massachusetts Memorial Medical Center ( Site 4103), Worcester, Massachusetts

Washington University School of Medicine-Obstetrics & Gynecology ( Site 4146), Saint Louis, Missouri

The Center of Hope ( Site 4109), Reno, Nevada

John Theurer Cancer Center at Hackensack University Medical Center ( Site 4118), Hackensack, New Jersey

Atlantic Health System Morristown Medical Center ( Site 4135), Morristown, New Jersey

Holy Name Medical Center ( Site 4115), Teaneck, New Jersey

New York - Presbyterian Brooklyn Methodist Hospital ( Site 4134), Brooklyn, New York

Perlmutter Cancer Center at NYU Langone Hospital - Long Island ( Site 4156), Mineola, New York

Laura and Isaac Perlmutter Cancer Center ( Site 4106), New York, New York

Icahn School of Medicine at Mount Sinai-Department of Obstetrics, Gynecology, and Reproductive Scie ( Site 4128), New York, New York

Good Samaritan Hospital Medical Center ( Site 4139), West Islip, New York

Duke Cancer Institute ( Site 4120), Durham, North Carolina

Sanford Health Roger Maris Cancer Center ( Site 4158), Fargo, North Dakota

University of Cincinnati Medical Center ( Site 4136), Cincinnati, Ohio

The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C ( Site 4125), Columbus, Ohio

Sidney Kimmel Cancer Center - Jefferson Health ( Site 4157), Philadelphia, Pennsylvania

AHN West Penn Hospital-Gynecologic Oncology ( Site 4111), Pittsburgh, Pennsylvania

Asplundh Cancer Pavilion ( Site 4107), Willow Grove, Pennsylvania

Women & Infants Hospital ( Site 4138), Providence, Rhode Island

Sanford Cancer Center-Gynecologic Oncology ( Site 4121), Sioux Falls, South Dakota

The West Clinic, PLLC dba West Cancer Center ( Site 4102), Germantown, Tennessee

Houston Methodist Hospital-Obstetrics and Gynecology ( Site 4130), Houston, Texas

Texas Oncology - San Antonio ( Site 8005), San Antonio, Texas

Texas Oncology - Gulf Coast ( Site 8006), The Woodlands, Texas

Hospital Británico de Buenos Aires-Oncology ( Site 1002), Ciudad autónoma de Buenos Aires, Buenos Aires

Instituto Argentino de Diagnóstico y Tratamiento (IADT) ( Site 1008), Buenos Aires, Caba

Instituto Alexander Fleming-Alexander Fleming ( Site 1007), Ciudad Autónoma de Buenos Aires, Caba

Hospital Aleman-Oncology ( Site 1001), Buenos Aires, Not set

Instituto de Oncología Angel H. Roffo ( Site 1003), Buenos Aires, Not set

Centro de Educación Médica e Investigaciones Clínicas (CEMIC) ( Site 1004), Buenos Aires, Not set

Fundación CORI para la Investigación y Prevención del Cáncer ( Site 1006), La Rioja, Not set

GenesisCare North Shore ( Site 1103), St Leonards, New South Wales

Blacktown Hospital ( Site 1101), Sydney, New South Wales

Royal Brisbane and Women's Hospital ( Site 1102), Brisbane, Queensland

Epworth Freemasons ( Site 1104), East Melbourne, Victoria

Frankston Hospital ( Site 1105), Frankston, Victoria

Medizinische Universitaet Innsbruck-Univ.-Klinik f. Gynäkologie und Geburtshilfe ( Site 1201), Innsbruck, Tirol

Medizinische Universität Wien ( Site 1202), Wien, Not set

AZ Maria Middelares-IKG ( Site 1305), Gent, Oost-Vlaanderen

UZ Gent-Medical oncology ( Site 1303), Gent, Oost-Vlaanderen

UZ Leuven-Gynecologic Oncology ( Site 1301), Leuven, Vlaams-Brabant

AZ Delta vzw-Oncology ( Site 1302), Roeselare, West-Vlaanderen

CHU UCL Namur/Site Sainte Elisabeth-Trial Office ( Site 1304), Namur, Not set

Hospital São Domingos ( Site 1365), Sao Luis, Maranhao

Centro Oncologico do Triangulo ( Site 1360), Uberlândia, Minas Gerais

Hospital Moinhos de Vento ( Site 1359), Porto Alegre, Rio Grande Do Sul

Instituto Joinvilense de Hematologia e Oncologia ( Site 1353), Joinville, Santa Catarina

Instituto de Ensino e Pesquisa ( Site 1355), Sorocaba, Sao Paulo

Instituto de Educação, Pesquisa e Gestão em Saúde ( Site 1352), Rio de Janeiro, Not set

Hospital Samaritano De Sao Paulo ( Site 1367), Sao Paulo, Not set

A. C. Camargo Cancer Center ( Site 1351), Sao Paulo, Not set

IBCC - Núcleo de Pesquisa e Ensino ( Site 1366), Sao Paulo, Not set

Arthur J.E. Child Comprehensive Cancer Centre ( Site 1413), Calgary, Alberta

Cross Cancer Institute ( Site 1414), Edmonton, Alberta

BC Cancer Vancouver ( Site 1415), Vancouver, British Columbia

Trillium Health Partners - Credit Valley Hospital ( Site 1410), Mississauga, Ontario

CIUSSS- saguenay-Lac-Saint-Jean ( Site 1408), Chicoutimi, Quebec

CIUSSS de l'Est-de-l'Île-de-Montréal ( Site 1405), Montreal, Quebec

Centre Hospitalier de l'Université de Montréal ( Site 1403), Montréal, Quebec

McGill University Health Centre ( Site 1404), Montréal, Quebec

James Lind Centro de Investigacion del Cancer ( Site 1504), Temuco, Araucania

Centro de Estudios Clínicos SAGA-CECSAGA ( Site 1505), Santiago., Region M. De Santiago

Pontificia Universidad Catolica de Chile ( Site 1503), Santiago, Region M. De Santiago

Bradfordhill-Clinical Area ( Site 1501), Santiago, Region M. De Santiago

Second Affiliated hospital of Anhui Medical University-Oncology ( Site 1635), Hefei, Anhui

Beijing Obstetric and Gynecology Hospital ( Site 1653), Beijing, Beijing

Fujian Cancer Hospital-Gynecological Oncology Surgery ( Site 1627), Fuzhou, Fujian

The First Affiliated hospital of Xiamen University-Obstetrics and gynecology department ( Site 1613), Xiamen, Fujian

Sun Yat-sen Memorial Hospital, Sun Yat-sen University ( Site 1634), Guangzhou, Guangdong

Sun Yat-sen University Cancer Center ( Site 1604), Guangzhou, Guangdong

Cancer Hospital of Shantou University Medical College ( Site 1642), Shantou, Guangdong

Affiliated Hospital of Guangdong Medical University ( Site 1614), Zhanjiang, Guangdong

Guangxi Medical University Affiliated Tumor Hospital-Gynecological oncology ( Site 1622), Nanning, Guangxi

Hainan General Hospital ( Site 1636), Haikou, Hainan

Harbin Medical University Cancer Hospital-Gynecological Radiotherapy Department ( Site 1652), Harbin, Heilongjiang

Henan Cancer Hospital ( Site 1618), Zhengzhou, Henan

The Second Affiliated Hospital of Zhengzhou University ( Site 1640), Zhengzhou, Henan

Union Hospital Tongji Medical College Huazhong University of Science and Technology ( Site 1621), Wuhan, Hubei

Hubei Cancer Hospital-Hubei Cancer Hospital ( Site 1607), Wuhan, Hubei

Xiangya Hospital Central South University-Gynecology ( Site 1603), Changsha, Hunan

Hunan Cancer Hospital ( Site 1623), Changsha, Hunan

Nanjing First Hospital ( Site 1649), Nanjing, Jiangsu

Jiangxi Maternal and Child Health Hospital-Oncology Department ( Site 1625), Nanchang, Jiangxi

LinYi Cancer Hospital-Gastrology department ( Site 1630), Linyi, Shandong

Obstetrics & Gynecology Hospital of Fudan University ( Site 1617), Shanghai, Shanghai

Shanghai First Maternity and Infant Hospital-Gynecology department ( Site 1626), Shanghai, Shanghai

West China Second University Hospital, Sichuan University ( Site 1602), Chengdu, Sichuan

Sichuan Cancer hospital-Oncology ( Site 1650), Chengdu, Sichuan

Xinjiang Medical University Cancer Hospital - Urumqi ( Site 1648), Urumqi, Xinjiang

Yunnan Province Cancer Hospital-Gynecology Department ( Site 1641), Kunming, Yunnan

The Affiliated Women's Hospital of Zhejiang University-Obstetrics and Gynecology ( Site 1609), Hangzhou, Zhejiang

Zhejiang Cancer Hospital-Oncology ( Site 1601), Hangzhou, Zhejiang

Taizhou Hospital of Zhejiang Province ( Site 1633), Linhai, Zhejiang

The First Affiliated Hospital of Wenzhou Medical University ( Site 1615), Wenzhou, Zhejiang

Fakultní Nemocnice Brno-Gynekologicko-porodnicka klinika ( Site 1704), Brno, Brno-mesto

Fakultni nemocnice Ostrava-Gynekologicko-porodnicka klinika ( Site 1703), Ostrava, Moravskoslezsky Kraj

Nemocnice AGEL Novy Jicin a.s.-Oddeleni radioterapie a onkologie ( Site 1706), Nový Jiín, Novy Jicin

Fakultni nemocnice Olomouc-Onkologicka klinika ( Site 1702), Olomouc, Olomoucky Kraj

Fakultni nemocnice Kralovske Vinohrady ( Site 1707), Praha, Praha 10

Vseobecna fakultni nemocnice v Praze-Gynekologicko-porodnicka klinika 1.LF a VFN ( Site 1705), Praha, Praha 2

Fakultni nemocnice Bulovka-Gynekologicko-porodnicka klinika ( Site 1701), Praha, Praha 8

Herlev and Gentofte Hospital-Department of Oncology ( Site 1801), Copenhagen, Hovedstaden

Rigshospitalet-Dept. of Oncology ( Site 1803), Copenhagen, Hovedstaden

Aarhus Universitetshospital, Skejby ( Site 1802), Aarhus, Midtjylland

Tampereen yliopistollinen sairaala ( Site 1901), Tampere, Pirkanmaa

Kuopion Yliopistollinen Sairaala ( Site 1904), Kuopio, Pohjois-Savo

Helsinki University Hospital - Comprehensive Cancer Center (HYKS - Syöpäkeskus) ( Site 1902), Helsinki, Uusimaa

Turku University Hospital-Department of Obstetrics and Gynecology ( Site 1903), Turku, Varsinais-Suomi

Institut Bergonié - Centre Régional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest ( Site 2002), Bordeaux, Aquitaine

ROC37 ( Site 2010), Chambray Les Tours, Centre

Centre Armoricain de Radiotherapie Imagerie medicale et Oncologie ( Site 2001), Plerin, Cotes-d Armor

CHU Besançon ( Site 2009), Besançon, Doubs

Institut Claudius Regaud ( Site 2006), Toulouse, Haute-Garonne

Institut Regional du Cancer Montpellier ( Site 2008), Montpellier, Herault

Centre Eugène Marquis Rennes - Centre de Lutte Contre le Cancer ( Site 2003), Rennes, Ille-et-Vilaine

Centre Oscar Lambret ( Site 2007), Lille, Nord-Pas-de-Calais

CENTRE LEON BERARD ( Site 2004), Lyon Cedex08, Rhone-Alpes

Groupe Hospitalier Diaconesses Croix Saint Simon ( Site 2005), Paris, Not set

SLK-Kliniken Heilbronn ( Site 2107), Heilbronn, Baden-Wurttemberg

Universitätsmedizin Mannheim-Department of Obstetrics and Gynecology ( Site 2101), Mannheim, Baden-Wurttemberg

MVZ für Hämatologie und Onkologie Ravensburg GmbH - Studienzentrum ( Site 2110), Ravensburg, Baden-Wurttemberg

Universitaetsklinikum Tuebingen ( Site 2111), Tübingen, Baden-Wurttemberg

Klinikum der Universität München Großhadern-Klinik und Poliklinik für Frauenheilkunde und Geburtshi ( Site 2109), Munich, Bayern

Kliniken Essen-Mitte, Evangelische Huyssens-Stiftung ( Site 2104), Essen, Nordrhein-Westfalen

Universitaetsklinikum Carl Gustav Carus Dresden-Klinik und Poliklinik für Frauenheilkunde und Gebur ( Site 2103), Dresden, Sachsen

Charité Campus Virchow-Klinikum ( Site 2102), Berlin, Not set

Agios Andreas Hospital Patras ( Site 2201), Patras, Achaia

Aretaieio Hospital Oncology Unit ( Site 2206), Athens, Attiki

Metropolitan Hospital-2nd Oncology Dept ( Site 2202), Athens, Attiki

Hygeia Hospital ( Site 2204), Marousi, Attiki

Cork University Hospital ( Site 2402), Cork, Not set

Mater Misericordiae University Hospital ( Site 2403), Dublin, Not set

St. James's Hospital-Cancer clinical trials office ( Site 2401), Dublin, Not set

Rambam Health Care Campus-Gyneco-oncology unit ( Site 2502), Haifa, Not set

Edith Wolfson Medical Center ( Site 2501), Holon, Not set

Shaare Zedek Medical Center ( Site 2503), Jerusalem, Not set

Rabin Medical Center ( Site 2505), Petah Tikva, Not set

Sheba Medical Center ( Site 2504), Ramat Gan, Not set

Sourasky Medical Center ( Site 2506), Tel Aviv, Not set

IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlin-SSD Oncologia medica Addarii ( Site 2603), Bologna, Emilia-Romagna

CRO-IRCCS ( Site 2609), Aviano, Friuli-Venezia Giulia

AOU Policlinico Umberto I ( Site 2606), Roma, Lazio

Istituto Europeo di Oncologia IRCCS ( Site 2607), Milano, Lombardia

Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Chirurgia Ginecologica ( Site 2605), Milan, Lombardia

Istituto Clinico Humanitas-U.O di Oncologia medica ed Ematologia ( Site 2610), Rozzano, Milano

Istituto di Candiolo IRCCS - Fondazione del Piemonte per l'O-Day Hospital Oncologico Multidisciplin ( Site 2613), Candiolo, Torino

Instituto Tumori Giovanni Paolo II-ONCOLOGIA MEDICA ( Site 2604), Bari, Not set

Azienda Ospedaliera Spedali Civili di Brescia-Obstetrics anf gynecology ( Site 2611), Brescia, Not set

Humanitas San Pio X Hospital ( Site 2614), Milano, Not set

Istituto Nazionale Tumori IRCCS Fondazione Pascale-S.C. Oncologia Sperimentale Uro-Genitale ( Site 2602), Napoli, Not set

Arcispedale Santa Maria Nuova ( Site 2612), Reggio Emilia, Not set

Fondazione Policlinico Universitario Agostino Gemelli IRCCS -Ginecologia Oncologica ( Site 2601), Roma, Not set

Ospedale Mauriziano-Ginecologia e Ostetricia ( Site 2608), Torino, Not set

Aichi Cancer Center ( Site 2714), Nagoya, Aichi

National Hospital Organization Shikoku Cancer Center ( Site 2705), Matsuyama, Ehime

Ehime University Hospital ( Site 2709), Toon, Ehime

Kurume University Hospital ( Site 2703), Kurume, Fukuoka

Gunma Prefectural Cancer Center ( Site 2708), Otashi, Gunma

Hokkaido University Hospital ( Site 2707), Sapporo, Hokkaido

University of Tsukuba Hospital ( Site 2713), Tsukuba, Ibaraki

Iwate Medical University Hospital ( Site 2712), Shiwa-gun, Iwate

Niigata Cancer Center Hospital ( Site 2701), Niigata-shi, Niigata

Saitama Medical University International Medical Center ( Site 2710), Hidaka, Saitama

Shizuoka Cancer Center ( Site 2716), Sunto-gun,, Shizuoka

National Cancer Center Hospital ( Site 2715), Chuo-ku, Tokyo

Cancer Institute Hospital of JFCR ( Site 2706), Koto, Tokyo

Showa Medical University Hospital ( Site 2719), Shinagawa, Tokyo

Keio University Hospital ( Site 2702), Shinjuku, Tokyo

National Hospital Organization Kyushu Cancer Center ( Site 2711), Fukuoka, Not set

Kagoshima City Hospital ( Site 2717), Kagoshima, Not set

Osaka International Cancer Institute ( Site 2718), Osaka, Not set

Seoul National University Bundang Hospital-Obstetrics and Gynecology ( Site 3505), Seongnam, Kyonggi-do

Seoul National University Hospital ( Site 3502), Seoul, Not set

Severance Hospital, Yonsei University Health System-Gynecologic cancer center ( Site 3503), Seoul, Not set

Asan Medical Center-Division of Gynecologic Oncology, Dept. of Obstetrics & Gynecology ( Site 3501), Seoul, Not set

Samsung Medical Center ( Site 3504), Seoul, Not set

Pantai Hospital Kuala Lumpur-Cancer Centre ( Site 2803), Kuala Lumpur, Not set

University Malaya Medical Centre ( Site 2801), Kuala Lumpur, Not set

COI Centro Oncologico Internacional S.A.P.I. de C.V. ( Site 2902), Coyoacan, Distrito Federal

Higiea Oncologia ( Site 2905), Mexico City, Distrito Federal

CENTRO MEDICO ZAMBRANO HELLION-Centro de Cáncer de Mama ( Site 2901), San Pedro Garza Garcia, Nuevo Leon

Oncare - Unidad Valle ( Site 2906), San Pedro Garza García, Nuevo Leon

Centro de Investigacion Clinica de Oaxaca ( Site 2907), Oaxaca de Juarez, Oaxaca

Radboudumc-Medical Oncology ( Site 3003), Nijmegen, Gelderland

Amsterdam UMC - locatie VUmc ( Site 3004), Amsterdam, Noord-Holland

Leids Universitair Medisch Centrum-Medical Oncology ( Site 3002), Leiden, Zuid-Holland

Stavanger Universitetssykehus ( Site 3103), Stavanger, Rogaland

Universitetssykehuset Nord-Norge HF ( Site 3101), Tromsø, Troms

Sorlandet Sykehus Kristiansand ( Site 3104), Kristiansand, Vest-Agder

Oslo universitetssykehus, Radiumhospitalet ( Site 3102), Oslo, Not set

Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 3201), Siedlce, Mazowieckie

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Ginekologii Onkologicznej ( Site 3203), Warszawa, Mazowieckie

Bialostockie Centrum Onkologii-Oddzial Onkologii Ginekologicznej ( Site 3204), Bialystok, Podlaskie

Wielkopolskie Centrum Onkologii im. Marii Skłodowskiej-Curie-Oddział Radioterapii i Onkologii Ginek ( Site 3202), Poznan, Wielkopolskie

Ad-Vance Medical Research-Research ( Site 3302), Ponce, Not set

Pan American Center for Oncology Trials - Ciudadela ( Site 3301), San Juan, Not set

UPR Comprehensive Cancer Center-Comprehensive Cancer Center Hospital ( Site 3304), San Juan, Not set

National Cancer Centre Singapore-Medical Oncology ( Site 3401), Singapore, Central Singapore

Institut Català d'Oncologia - L'Hospitalet-Medical Oncology ( Site 3608), L Hospitalet, Barcelona

Institut Català d'Oncologia (ICO) - Girona-Oncología Médica ( Site 3606), Girona, Gerona

Clinica Universidad de Navarra ( Site 3603), Madrid, Madrid, Comunidad De

Hospital Universitario 12 de Octubre-Medical Oncology ( Site 3607), Madrid, Madrid, Comunidad De

Hospital Universitario La Paz-Oncología Médica ( Site 3604), Madrid, Madrid, Comunidad De

Fundación Instituto Valenciano de Oncología-Oncologico ( Site 3605), Valencia, Valenciana, Comunitat

HOSPITAL CLINICO DE VALENCIA ( Site 3609), Valencia, Valenciana, Comunitat

Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 3602), Barcelona, Not set

Hospital Universitario Reina Sofia-Oncologia Medica ( Site 3601), Cordoba, Not set

Skånes Universitetssjukhus Lund ( Site 3702), Lund, Skane Lan

Karolinska Universitetssjukhuset Solna ( Site 3701), Stockholm, Stockholms Lan

University Hospital Basel-Gynecology & Gynecologic Oncology ( Site 3808), Basel, Basel-Stadt

Kantonsspital Graubünden-Medizin ( Site 3803), Chur, Grisons

Ospedale Regionale Bellinzona e Valli ( Site 3802), Bellinzona, Ticino

Inselspital Bern-Oncology ( Site 3801), Berne, Not set

University Hospitals Sussex NHS Foundation Trust ( Site 4006), East Sussex, Brighton And Hove

Royal Derby Hospital ( Site 4007), Derby, Derbyshire

ROYAL MARSDEN HOSPITAL (CHELSEA)-Gynaecology Research Centre ( Site 4002), London, England

The Royal Cornwall Hospital ( Site 4009), Truro, England

University College London Hospital-Cancer Clinical Trials Unit ( Site 4004), London, London, City Of

Guy's & St Thomas' NHS Foundation Trust-Oncology & Haematology Clinical Trials ( Site 4008), London, London, City Of

Hammersmith Hospital ( Site 4001), London, London, City Of

The Beatson West of Scotland Cancer Centre ( Site 4005), Glasgow, Scotland

Royal Marsden Hospital (Sutton)-Gynaecology Unit ( Site 4010), London, Sutton

The Christie NHS Foundation Trust-Medical Oncology ( Site 4003), Manchester, Not set

Conditions: Endometrial Cancer

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A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With Myeloproliferative Neoplasms

NCT06313593

Recruiting

This study is being conducted to assess the Safety, Tolerability, and Pharmacokinetics of INCB160058 in Participants With Myeloproliferative Neoplasms.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/14/2025

Locations: The University of Alabama At Birmingham, Birmingham, Alabama +29 locations

The University of Alabama At Birmingham, Birmingham, Alabama

Stanford University, Palo Alto, California

Moffitt Cancer Center, Tampa, Florida

Northwestern University, Chicago, Illinois

The University of Kansas Cancer Center Kucc University of Kansas Clinical Research Center, Fairway, Kansas

Dana Farber Cancer Institute, Boston, Massachusetts

University of Michigan, Ann Arbor, Michigan

Icahn School of Medicine At Mount Sinai, New York, New York

Cornell Medical Center, New York, New York

Sloan Kettering Institute For Cancer Research, New York, New York

Oregon Health & Science University, Portland, Oregon

University of Pennsylvania Health System, Philadelphia, Pennsylvania

Vanderbilt-Ingram Cancer Center, Nashville, Tennessee

Md Anderson Cancer Center, Houston, Texas

Princess Margaret Cancer Center, Toronto, Ontario

Hopital Maisonneuve-Rosemont, Montreal, Qc, Montreal, Quebec

McGill University Jewish General Hospital, Montreal, Quebec

Hospital Saint Louis, Paris, Not set

Institut Gustave Roussy, Villejuif Cedex, Not set

University Medical Center Rwth Aachen, Aachen, Not set

Universitatsklinikum Essen, Essen, Not set

Universitatsklinikum Halle (Saale), Halle, Not set

Aou Policlinico S. Orsola-Malpighi, Bologna, Not set

Azienda Ospedaliero-Universitaria Careggi (Aouc), Firenze, Not set

Fondazione Irccs Ca Granda Ospedale Maggiore, Milan, Not set

Haukeland University Hospital, Bergen, Not set

Oslo University Hospital, Oslo, Not set

Inselspital - Universitaetsspital Bern, Bern, Not set

Universitatsspital Zurich, Zuerich, Not set

Guys and St Thomas Nhs Foundation Trust, London, Not set

Conditions: Myeloproliferative Neoplasms

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Pembrolizumab and Brentuximab Vedotin vs GDP and Stem Cell Transplant for Relapsed/Refractory Hodgkin Lymphoma

NCT05180097

Recruiting

This study is being done to determine if two new drugs can shrink or eliminate classical Hodgkins lymphoma.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/14/2025

Locations: Concord Repatriation General Hospital, Concord, New South Wales +17 locations

Conditions: Hodgkin Lymphoma

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A Study Observing Everyday Effectiveness and Safety of the Drug Elafibranor in Participants With Primary Biliary Cholangitis Who Are Receiving Ongoing Treatment

NCT06447168

Recruiting

This study will collect information from participants with Primary Biliary Cholangitis (PBC) as they use the drug elafibranor in real world setting. PBC is a progressive rare liver disease in which tubes in the liver called bile ducts are damaged. The liver damage in PBC may lead to scarring (cirrhosis). PBC may also be associated with multiple symptoms including pruritus (itching) and fatigue. Many patients with PBC may require liver transplant or may die if the disease progresses and a liver... Read More

Gender:

ALL

Ages:

All

Trial Updated:

08/14/2025

Locations: Southern California Research Center, Coronado, California +41 locations

Southern California Research Center, Coronado, California

Cedars-Sinai Medical Center, Los Angeles, California

South Denver Gastroenterology,P.C., Englewood, Colorado

Yale University School of Medicine, New Haven, Connecticut

Schiff Center for Liver Diseases - University of Miami, Miami, Florida

Beth Israel Deaconess Medical Center, Liver Research Center, Boston, Massachusetts

Virtua Center for Liver Disease - Cherry Hill, Cherry Hill, New Jersey

Northwell Health Inc, Center for Liver Disease and Transplantation, Manhasset, New York

Cleveland Clinic Foundation, Cleveland, Ohio

Medical University of South Carolina (MUSC), Charleston, South Carolina

Liver Center of Texas, Dallas, Texas

Baylor College of Medicine - Advanced Liver Therapies, Houston, Texas

Velocity Clinical Research, Katy, Texas

Bon Secours Richmond Community Hospital LLC. d/b/a Bon Secours Liver Institute of Richmond, Richmond, Virginia

Virginia Commonwealth University Medical Center - West Hospital, Richmond, Virginia

Gastro health & Nutrition, Seattle, Washington

Medizinische Universitaetsklinik Graz, Graz, Not set

Medical University Innsbruck, Innsbruck, Not set

University of Calgary, Calgary, Not set

(G.I.R.I) GI Research Institute Foundation, Vancouver, Not set

Charite Universitatsmedizin Berlin, Berlin, Not set

DRK Kliniken Berlin Mitte, Berlin, Not set

Klinikum der Johann Wolfgang Goethe-Universitaet, Frankfurt, Not set

Studiengesellschaft BSF, Halle, Not set

Gastroenterologsiche Studiengesellschaft Herne, Herne, Not set

Universitaet des Saarlandes, Homburg, Not set

Universitaetsklinikum Leipzig, Leipzig, Not set

Hospital of the Merciful Brothers Trier, Trier, Not set

General Hospital of Athens Laiko, Athens, Not set

University Hospital of Heraklion, Heraklion, Not set

University General Hospital of Patras, Patras, Not set

Clemenceau Medical Center Hospital, Dubai, Not set

Mediclinic Airport Road Hospital, Dubai, Not set

Sheikh Shakhbout Medical City, Dubai, Not set

Aberdeen Royal Infirmary NHS Grampian Grampian Health Board, Aberdeen, Not set

Queen Elizabeth Hospital Birmingham - University Hospitals Birmingham NHS Foundation Trust, Birmingham, Not set

Bradford Royal Infirmary - Bradford Teaching Hospitals NHS Foundation, Bradford, Not set

Hull Royal Infirmary - Hull University Teaching Hospitals NHS Trust, Hull, Not set

King's College Hospital NHS Foundation Trust, London, Not set

The Newcastle upon Tyne Hospitals NHS Foundation Trust - Freeman Hospital, Newcastle, Not set

Queen's Medical Centre - Nottingham University Hospitals NHS Trust, Nottingham, Not set

John Radcliffe Hospital - Oxford University Hospitals NHS Foundation Trust, Oxford, Not set

Conditions: Primary Biliary Cholangitis

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The ENCIRCLE Trial

NCT04153292

Recruiting

This study will establish the safety and effectiveness of the SAPIEN M3 System in subjects with symptomatic, at least 3+ mitral regurgitation (MR) for whom commercially available surgical or transcatheter treatment options are deemed unsuitable. Following completion of enrollment, subjects will be eligible for enrollment in the continued access phase of the trial.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/14/2025

Locations: Heart Center Hospital, Huntsville, Alabama +67 locations

Heart Center Hospital, Huntsville, Alabama

Banner University Medical Center, Phoenix, Arizona

Arizona Cardiovascular Research Center, Phoenix, Arizona

TMC Healthcare, Tucson, Arizona

Scripps Health, La Jolla, California

Good Samaritan Hospital, Los Angeles, California

Cedars-Sinai Medical Center, Los Angeles, California

Kaiser Sunset LA, Los Angeles, California

Saint Joseph Hospital, Orange, California

California Pacific Medical Center, San Francisco, California

UC Health Northern Colorado (Medical Center of the Rockies), Loveland, Colorado

Delray Medical Center, Delray Beach, Florida

Cardiac & Vascular Institute Foundation, Gainesville, Florida

Ascension St. Vincent's Hospital, Jacksonville, Florida

Naples Community Hospital, Naples, Florida

Sarasota Memorial Hospital, Sarasota, Florida

Emory University, Atlanta, Georgia

Piedmont Healthcare, Atlanta, Georgia

Rush University Medical Center, Chicago, Illinois

Northshore University Health System, Glenview, Illinois

St. Vincent Heart Center of Indiana, Indianapolis, Indiana

University of Kansas, Kansas City, Kansas

Cardiovascular Research Institute of Kansas (CRIOK), Wichita, Kansas

Our Lady of the Lake Regional Medical Center, Baton Rouge, Louisiana

Medstar Union Memorial Hospital, Baltimore, Maryland

Massachusetts General Hospital, Boston, Massachusetts

Brigham & Women's, Boston, Massachusetts

Henry Ford, Detroit, Michigan

Minneapolis Heart, Minneapolis, Minnesota

Mayo Clinic, Rochester, Minnesota

CentraCare, Saint Cloud, Minnesota

Saint Luke's Kansas City, Kansas City, Missouri

St. Patrick Hospital, Missoula, Montana

Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire

Morristown Medical Center, Morristown, New Jersey

Robert Wood Johnson University Hospital, New Brunswick, New Jersey

University of Buffalo, Buffalo, New York

Weill Cornell Medicine, New York, New York

Carolinas Medical Center, Charlotte, North Carolina

Novant Health and Vascular Institute, Charlotte, North Carolina

The Christ Hospital, Cincinnati, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Mount Carmel East Hospital, Columbus, Ohio

Oklahoma Heart Hospital, Oklahoma City, Oklahoma

Oklahoma Heart Institute, Tulsa, Oklahoma

UPMC Heart and Vascular Institute, Mechanicsburg, Pennsylvania

Alleghany General Hospital, Pittsburgh, Pennsylvania

Saint Thomas Health, Nashville, Tennessee

Austin Heart, Austin, Texas

HCA Houston Healthcare Medical (SCRI), Houston, Texas

UT Memorial Hermann, Houston, Texas

Intermountain Medical Center, Murray, Utah

Sentara Norfolk, Norfolk, Virginia

Carilion Roanoke Memorial Hospital, Roanoke, Virginia

University of Washington Seattle, Seattle, Washington

University of Wisconsin, Madison, Wisconsin

The Prince Charles Hospital, Chermside, Queensland

Royal Prince Alfred Hospital, Camperdown, Not set

Laval University, Quebec City, Quebec

St. Michael's, Toronto, Not set

St. Pauls, Vancouver, Not set

Shaare Zedek Medical Center, Jerusalem, Not set

Rabin Medical Center, Petah Tikva, Not set

Sheba Medical Center, Ramat Gan, Not set

Leiden University Medical Center, Leiden, South Holland

Rotterdam Erasmus MC, Rotterdam, South Holland

Saint Thomas Hospital, London, Not set

Saint Bartholomew's Medical Center, Oxford, Not set

Conditions: Mitral Regurgitation, Mitral Valve Insufficiency

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