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All Clinical Trials in Canada
A listing of 3905 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
2389 - 2400 of 3905
A Study Comparing Abelacimab to Apixaban in the Treatment of Cancer-associated VTE
Recruiting
This is a Phase 3,multicenter, randomized, open-label, blinded endpoint evaluation study comparing the effect of abelacimab relative to apixaban on venous thromboembolism (VTE) recurrence and bleeding in patients with cancer associated VTE (ASTER)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/18/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado +218 locations
Conditions: Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolism
A Study Comparing Abelacimab to Dalteparin in the Treatment of Gastrointestinal/Genitourinary Cancer and Associated VTE
Recruiting
This is a Phase 3, multicenter, open-label, blinded endpoint study to evaluate the effect of abelacimab relative to dalteparin on venous thromboembolism (VTE) recurrence and bleeding in patients with gastrointestinal (GI)/genitourinary (GU) cancer associated VTE (Magnolia)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/18/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado +184 locations
Conditions: Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolism
The Family-ICU Trial
Recruiting
Family inclusion in adult intensive care unit (ICU) rounds is recommended by critical care professional societies, yet widespread uptake of this practice is limited. A key barrier cited by ICU clinicians is insufficient evidence to support this practice. There is a need for robust evidence to support family participation in adult ICU rounds and influence change to routine clinical care. The primary purpose of this study is to assess whether family participation in adult ICU rounds improves famil... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/18/2024
Locations: Jewish General Hospital, Montreal, Quebec +1 locations
Conditions: Virtual Care, Family Engagement, Patient and Family Engagement, Health Care Delivery, Family-centered Care, Physician Rounds, Critical Care, Intensive Care
STABILITY 2: Anterior Cruciate Ligament Reconstruction +/- Lateral Tenodesis With Patellar vs Quad Tendon
Recruiting
Anterior cruciate ligament (ACL) rupture is one of the most common musculoskeletal injuries in young individuals, particularly those that are active in sports. Up to 30% of individuals under the age of 20 years suffer a re-injury to the reconstructed ACL. Revision ACLR has been associated with degeneration of the articular cartilage and increased rates of meniscal tears, increasing the risk of post-traumatic osteoarthritis (PTOA), additional surgical procedures, reduced physical function and qua... Read More
Gender:
ALL
Ages:
Between 14 years and 25 years
Trial Updated:
12/17/2024
Locations: Stanford University, Redwood City, California +30 locations
Conditions: Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction, Joint Instability
Calgary Registry for Advanced and Therapeutic Endoscopy
Recruiting
The aim of the Calgary Registry for Advanced and Therapeutic Endoscopy (CReATE) is to be a high-fidelity prospective multi-centre registry. The study population consists of consecutive adult ERCP patients from September 2018 to August 2022. Informed consent is acquired for each patient. All relevant pre-procedural, procedural, peri-procedural and post-procedural data are captured in real time by a full-time third-party research assistant directly observing procedures. Outcomes are ascertained by... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/17/2024
Locations: University of Calgary, Calgary, Alberta
Conditions: Biliary Disease, Pancreatic Diseases
Short-term Intravenous Fluids for Prevention of Post-ERCP Pancreatitis
Recruiting
This study will explore the efficacies of several practical short-term (peri-procedural) intravenous fluid regimens in the prevention of post- endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP). PEP is the most common serious ERCP-related adverse event (AE), occurring in 5-15% of patients, and associated with significant morbidity, mortality, and healthcare utilization. Given the current lack of data on effectiveness of short-term fluid regimens in PEP prevention to inform... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
12/17/2024
Locations: Peter Lougheed Centre, Calgary, Alberta
Conditions: Post-ERCP Acute Pancreatitis
Predictors of Relapse in Major Depressive Disorder
Recruiting
Major depressive disorder (MDD) is a common condition involving recurring periods of depression. One of the major challenges faced by people with MDD is that the episodes of depression tend to recur even after they are successfully treated. Currently, it is hard to predict when a depressive episode will recur. Being able to forecast this would help healthcare providers monitor patients and prevent relapse.
The purpose of this study is to monitor features such as clinical symptoms, physical acti... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
12/17/2024
Locations: Nova Scotia Health, Halifax, Nova Scotia
Conditions: Major Depressive Disorder (MDD)
A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer
Recruiting
This is a randomized controlled trial to compare survival for patients who undergoe robotic assisted laparoscopy versus open hysterectomy and lymph node assessment for the treatment of early stage cervical cancer.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/16/2024
Locations: Western Regional Medical Center LLC, Goodyear, Arizona +135 locations
Conditions: Cervical Cancer
SKB264 in Combination With Pembrolizumab in Subjects With Selected Solid Tumors
Recruiting
The purpose of this study is to evaluate the efficacy and safety of combination of SKB264 and Pembrolizumab in patients with selected solid tumors including cervical cancer, urothelial cancer, ovarian cancer, prostate cancer,advanced endometrial cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/16/2024
Locations: Community Clinical Research Center, Anderson, Indiana +50 locations
Conditions: Solid Tumor
Syncope Trial to Understand Tilt Testing or ECG Recording Tenth Prevention of Syncope Trial
Recruiting
The Study To Understand Tilt Tests versus Extended Recordings (STUTTER, POST 10) will test the hypothesis that first performing a diagnostic HUT in older patients with syncope of unknown cause will provide earlier and more diagnoses than inserting an ICM.
Gender:
ALL
Ages:
Between 50 years and 110 years
Trial Updated:
12/16/2024
Locations: University of Calgary, Calgary, Alberta
Conditions: Syncope
The Impact of Working Memory and Reward Markers on DLPFC Activity in Treatment-resistant Depression
Recruiting
Major Depressive Disorder (MDD) is a very common illness that is usually treated with antidepressant medication. Depression can be caused by many things such as childhood experiences, genetics, and changes in the way the body and brain function. For those with depression where medication and psychotherapy have limited benefit, repetitive transcranial magnetic stimulation (rTMS) is an effective treatment. rTMS is a treatment that involves stimulating certain areas of the brain with magnetic field... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/16/2024
Locations: Unity Health Toronto, Toronto, Ontario
Conditions: Major Depressive Disorder, Treatment Resistant Depression
Re-Purposing the Ordering of Routine Laboratory Tests in Hospitals in British Columbia
Recruiting
The goal of this stepped-wedge cluster randomized trial is to assess the impact of a laboratory test overuse intervention bundle on laboratory test utilization in 6 health authorities (16 hospitals) in British Columbia. The main question it aims to answer is if the intervention bundle, inclusive of healthcare provider and patient engagement tools, can be effectively implemented for hospitalized medical inpatients in 16 hospitals across BC and reduce laboratory test over-use. Researchers will com... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/16/2024
Locations: University Hospital of Northern British Columbia, Prince George, British Columbia +3 locations
Conditions: Hospital Acquired Condition
2389 - 2400 of 3905