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All Clinical Trials in Canada
A listing of 3904 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
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AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Relapsed/Refractory Multiple Myeloma
Recruiting
This is a Phase I/II, modular, open-label, multicenter, dose escalation, and dose expansion/optimization study to evaluate the safety, tolerability, PK, immunogenicity, pharmacodynamics, and preliminary efficacy of AZD0305 in participants with RRMM.
This is a Phase I/II, modular, open-label, multicenter, dose escalation, and dose expansion/optimization study to evaluate the safety, tolerability, PK, immunogenicity, pharmacodynamics, and preliminary efficacy of AZD0305 in participants with RRMM. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/13/2025
Locations: Research Site, Duarte, California +32 locations
Research Site, Duarte, California
Research Site, Irvine, California
Research Site, Atlanta, Georgia
Research Site, Boston, Massachusetts
Research Site, Ann Arbor, Michigan
Research Site, Saint Louis, Missouri
Research Site, New York, New York
Research Site, Philadelphia, Pennsylvania
Research Site, Fairfax, Virginia
Research Site, Melbourne, Not set
Research Site, Nedlands, Not set
Research Site, Hamilton, Ontario
Research Site, Ottawa, Ontario
Research Site, Montréal, Quebec
Research Site, Beijing, Not set
Research Site, Changsha, Not set
Research Site, Guangzhou, Not set
Research Site, Shenyang, Not set
Research Site, Lille, Not set
Research Site, Nantes, Not set
Research Site, Essen, Not set
Research Site, Freiburg, Not set
Research Site, Hamburg, Not set
Research Site, Lübeck, Not set
Research Site, Nürnberg, Not set
Research Site, Würzburg, Not set
Research Site, Kashiwa, Not set
Research Site, Nagoya-shi, Not set
Research Site, Yamagata-shi, Not set
Research Site, Madrid, Not set
Research Site, Madrid, Not set
Research Site, Pamplona, Not set
Research Site, Salamanca, Not set
Conditions: Multiple Myeloma
RAdiolabeled Perfusion to Identify Coronary Artery Disease Using WAter To Evaluate Responses of Myocardial FLOW (RAPID-WATER-FLOW)
Recruiting
This a Phase 3, prospective, open-label, multicenter study of \[15-O\]-H2O injection for PET imaging of subjects with suspected CAD. Approximately 182 evaluable participants with suspected CAD referred for testing will be included in the study at approximately 10 study sites in the United States and Europe. Approximately 215 participants will be enrolled to account for an estimated 15% drop-out rate. Screening assessments will occur prior to enrollment to confirm eligibility. All participants wi... Read More
This a Phase 3, prospective, open-label, multicenter study of \[15-O\]-H2O injection for PET imaging of subjects with suspected CAD. Approximately 182 evaluable participants with suspected CAD referred for testing will be included in the study at approximately 10 study sites in the United States and Europe. Approximately 215 participants will be enrolled to account for an estimated 15% drop-out rate. Screening assessments will occur prior to enrollment to confirm eligibility. All participants will receive two doses of \[15-O\]-H2O as part of a single PET imaging session (one dose at rest and one during pharmacological stress with adenosine). A safety follow-up phone call will occur 24 ± 8 hrs after completion of the \[15-O\]-H2O scan. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/13/2025
Locations: University of Iowa, Iowa City, Iowa +12 locations
University of Iowa, Iowa City, Iowa
BAMF Healthcare, Grand Rapids, Michigan
Mayo Clinic, Rochester, Minnesota
Washington University, Saint Louis, Missouri
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
UT Southwestern Medical Center, Dallas, Texas
University of Virginia Medical Center, Charlottesville, Virginia
University of Ottawa Heart Institute, Ottawa, Ontario
Aarhus University Hospital, Aarhus, Not set
University Hospital Freiburg, Clinic for Nuclear Medicine, Freiburg, Not set
Department of Cardiology and Angiology, Hannover Medical School, Hannover, Not set
Sahlgrenska University Hospital, Gothenburg, Not set
Norrland University Hospital Heart Center, Umeå, Not set
Conditions: Coronary Artery Disease
A Study to Evaluate ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Unresectable or Metastatic Melanoma
Recruiting
The purpose of this study is to assess the efficacy, safety, and immunogenicity of ABP 206 compared with Nivolumab in Subjects with Treatment-Naïve Unresectable or Metastatic Melanoma.
The purpose of this study is to assess the efficacy, safety, and immunogenicity of ABP 206 compared with Nivolumab in Subjects with Treatment-Naïve Unresectable or Metastatic Melanoma. Read Less
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
08/13/2025
Locations: Cancer and Blood Specialty clinic, Long Beach, California +183 locations
Cancer and Blood Specialty clinic, Long Beach, California
Fort Wayne Medical Oncology and Hematology - Office of Clinical Research, Fort Wayne, Indiana
Our Lady of the Lake Physicians Group-Medical Oncology-Woman's Pavilion, Baton Rouge, Louisiana
University of Maryland Medical Center-Greenebaum Cancer Ctr, Baltimore, Maryland
Oncology Hematology Associates, Springfield, Missouri
Hematology-Oncology Associates-CNY, East Syracuse, New York
Fundación CENIT, Buenos Aires, Ciudad Autónoma De Buenos Aire
Centro De Investigaciones Medicas Mar Del Plata (CIMMDP) - Rheumatology, Mar del Plata, Río Negro
Clínica Viedma, Viedma, Río Negro
Instituto de Oncologia de Rosario, Rosario, Santa Fe
ISIS Clinica Especializada, Santa Fe, Not set
Clinical Center University of Sarajevo - Clinic of Oncology, Sarajevo, Kanton Sarajevo
University Clinical Center of Republic of Srpska, Banja Luka, Republika Srpska
University Clinical Center Tuzla - Oncology, Hematology and Radio, Tuzla, Tuzlanski Kanton
Cantonal hospital Zenica - Oncology, Zenica, Zeničko-dobojski Kanton
Dr. Everett Chalmers Hospital - Oncology, Fredericton, New Brunswick
Centro de Investigacion y Desarrollo Oncologico, Temuco, Araucanía
IC La Serena Research, La Serena, Coquimbo
Icegclinic Research & Care, Estacion Central, Santiago
Oncocentro APYS, Valparaiso, Valparaíso
University Hospital Centre Zagreb - Oncology department, Zagreb, Grad Zagreb
Poliklinika Anova, Zagreb, Grad Zagreb
Klinicki bolnicki centar Osijek, Osijek, Osjecko-baranjska Županija
FN Hradec Kralove - Klinika onkologie a radioterap, Hradec Kralove, Moravskoslezský Kraj
Vseobecna fakultni nemocnice v Praze - Dermatovenerologicka, Praha 2, Not set
East Tallinn Central Hospital, Tallinn, Harjumaa
Tartu University Hospital, Tartu, Tartumaa
CHU de Poitiers, Poitier, Haute-Vienne
Centre Hospitalier De Saint Malo, Rennes, Ille-et-Vilaine
C.H.R.U Hopital Claude Huriez - Dermatologie, Lille, Nord
High Technology Hospital MedCenter LTD, Batumi, Ajaria
LLC "Todua Clinic", Tbilisi, Not set
LTD "Israel-Georgian Medical Research Clinic Healthycore", Tbilisi, Not set
JSC "K.Eristavi National Center of Experimental and Clinical Surgery", Tbilisi, Not set
LTD "Multprofile Clinic Consilium Medulla" - Oncology, Tbilisi, Not set
Goethe University Frankfurt, Frankfurt/Main, Hessen
Philipps-University Marburg, Marburg, Hessen
University Hospital of Cologne, Köln, Nordrhein-Westfalen
Pécsi Tudományegyetem - Pszichiátriai És Pszichoter, Szeged, Not set
Ospedale Maggiore Di Crema - Oncologia e Day Hospital oncologico, Crema, Cremona
IRST Dino Amadori (IRST IRCCS) - UNK, Meldola, Forli
PO Ospedale San Vincenzo - Oncologia Medica, Taormina, Messina
Istituto Clinico Humanitas, Rozzano, Milano
AO Ss Antonio, Biagio e Arrigo, Alessandria, Not set
AUO Consorziale-Policlinico Bari, Bari, Not set
Istituto dei Tumori Giovanni Paolo II - Oncologia Medica - Tumori Rari e Melanoma, Bari, Not set
ASST Papa Giovanni XXIII - Oncologia, Bergamo, Not set
AOU Careggi, Firenze, Not set
IRCCS Ca'Granda Maggiore Policlinic, Milano, Not set
Ospedale San Raffaele, IRCCS, Milano, Not set
AOU Luigi Vanvitelli, Napoli, Not set
Azienda Ospedaliera Universitaria Federico II, Napoli, Not set
Azienda Sanitaria Locale Napoli 1 Centro (ASL Napoli 1) - Ospedale del Mare, Napoli, Not set
Fondazione IRCCS Policlinico San Matteo, Pavia, Not set
Arcispedale Santa Maria Nuova, Reggio Emilia, Not set
Fondazione Policlinico Universitario Campus Bio-medico - Oncologia Medica, Roma, Not set
IRCCS IFO, Istituto Nazionale dei Tumori Regina Elena (IRE), Roma, Not set
Istituto Dermopatico dell'Immacolata (IDI) - IRCCS - Oncologia, Roma, Not set
Osp Isola Tiberina-Gemelli Isola, Roma, Not set
AOU Senese, Policlinico Le Scotte, Siena, Not set
Ospedale di Circolo, Presidio di Varese - Oncologia, Varese, Not set
Al Khalidi Hospital and Medical Center - Research, Amman, 'Ammān
The Speciality Hospital (TSH) / Advanced Clinical Center, Amman, 'Ammān
King Hussein Cancer Center, Amman, Not set
Pharmaceutical Research Center (KAUH), Irbid, Not set
Inje University Haeundae Paik Hospital - Oncology, Busan, Busan Gwang'yeogsi [Pusan-Kwan
The Catholic University of Korea, St. Vincent's Hospital, Suwon-si, Gyeonggido [Kyonggi-do]
Severance Hospital, Yonsei University Health System - Division of Medical Oncology, Department of In, Seoul, Seoul Teugbyeolsi [Seoul-T'ukp
Asan Medical Center - Oncology, Seoul, Seoul Teugbyeolsi [Seoul-T'ukp
Samsung Medical Center - Family Medicine, Seoul, Seoul Teugbyeolsi [Seoul-T'ukp
The Catholic University of Korea, Seoul St. Mary's Hospital - Hematology and Oncology, Seoul, Seoul Teugbyeolsi [Seoul-T'ukp
Saint George Hospital University Medical Center, Achrafieh, Beirut
Nini Hospital, Tripoli, Loubnâne Ech Chemâli
Hammoud Hospital University Medical Center (HHUMC) - Hemato-Oncology, Saida, Loubnâne Ej Jnoûbi
Ain Wazein Hospital - internal medicine, Beirut, Not set
American University of Beirut Medical Center - Haematology, Beirut, Not set
Hotel Dieu de France Hospital - Oncology, Beirut, Not set
National Cancer Institute - Conservative Tumour Therapy, Vilnius, Vilniaus Apskritis
Hospital Pulau Pinang, Pulau Pinang, Pahang
Sarawak General Hospital, Kuching, Sarawak
Institut Kanser Negara, Putrajaya, Selangor
Hospital Universiti Sains Malaysia, Kubang Kerian, Terengganu
Hospital Canselor Tuanku Muhriz UKM, Kuala Lumpur, Wilayah Persekutuan Kuala Lump
Pantai Hospital Kuala Lumpur, Kuala Lumpur, Wilayah Persekutuan Kuala Lump
Hospital Kuala Lumpur - Surgery, Kuala Lumpur, Wilayah Persekutuan Kuala Lump
Health Pharma Professional Research S.A de C.V., Ciudad de Mexico, Distrito Federal
Preparaciones Oncologicas SC, Leon, Guanajuato, Guanajuato
Centro de Inm Onc de Occ Sa de Cv, Guadalajra, Jalisco
iCan Oncology Center Centro Medico AVE, Monterrey, Nuevo León
Centro Medico Zambrano Hellion TecSalud, Monterrey, Nuevo León
Althian - Research Management Center, San Pedro Garza Garcia, Nuevo León
Centro de Estudios y Prevención del Cancer AC, Juchitan, Oaxaca
Hospital Angeles Centro Médico San Luis Potosí - Cardiologia, San Luis Potosi, San Luis Potosí
Neurosciences Hospital Angeles Culiacán - Neurociencias Estudios Clínicos S.C., Culiacan, Sinaloa
Centro de Atención e Investigación Clínica en Oncología, Merida, Yucatán
Centro de Investigación Médica Aguascalientes (CIMA) - Oncology, Aguascalientes, Not set
Boca Clinical Trials México, Guadalajara, Not set
Oncare Cancer Center Viaducto CdMx, Mexico City, Not set
ONCOCENTER PUEBLA - Dermatology, Puebla, Not set
Clinical Research Institute, Tlalnepantla de Baz, Not set
Arensia Exploratory Medicine - Moldova - IMSP Institutul Oncologic - Oncology, Chisinau, Not set
Amphia Ziekenhuis - Molengracht, Breda, Noord-Brabant
Baguio General Hospital and Medical Center - Oncology, Baguio City, Benguet
Cebu Doctors' University Hospital - Oncology, Cebu City, Cebu
The Medical City - Clinical Research Unit, Iloilo City, Iloilo
The Medical City - Neurology, Pasig City, Metropolitan Manila
Cagayan de Oro Medical Center - Internal Medicine, Cagayan De Oro City, Misamis Oriental
Center for Skin Research, Testing and Product Development, Makati City, National Capital Region
Philippine General Hospital, Manila/Ermita, National Capital Region
Cardinal Santos Madical Center, San Juan City, National Capital Region
Riverside Medical Center, Bacolod City, Negros Occidental
Centro Hospitalar de Setúbal - Oncologia, Setubal, Setúbal
Champalimaud Cancer Center, Lisboa, Not set
Unidade Local De Saude De Lisboa Ocidental E.P.E., Lisboa, Not set
Hospital da Luz, Lisboa, Not set
Centro Hospitalar de Lisboa Norte E.P.E. - H. Santa Maria Serviço de Oncologia Médica, Lisboa, Not set
Instituto Portugues de Oncologia de Lisboa Francisco Gentil - Oncologia Medica, Lisboa, Not set
Instituto Português Oncologia Francisco Gentil do Porto - Oncologia Medica, Porto, Not set
Institutul Oncologic Prof Dr Ion Chiricuta Cluj-Napoca, Cluj-Napoca, Cluj
Medisprof - Medical Oncology, Cluj-Napoca, Cluj
Radiotherapy Center Cluj - Medical Oncology, Floresti, Cluj
Oncolab - Medical Oncology, Craiova, Dolj
Centrul de Oncologie Sf Nectarie - Medical Oncology, Craiova, Dolj
Medical Center Gral, Ploiesti, Prahova
Spitalul Municipal Ploiesti, Ploiesti, Prahova
Oncocenter- Oncologie Clinica - Medical Oncology, Timisoara, Timis
Memorial Healthcare International - Oncology, Bucuresti, Not set
Institutul Oncologic Prof Dr Alexandru Trestioreanu Bucuresti, Bucuresti, Not set
Centrul de Oncologie Euroclinic, Iasi, Not set
Spitalul Clinic Judetean De Urgenta Sibiu, Sibiu, Not set
Institute for Oncology of Vojvodina, Clinic for Internal Oncology-Department of Soft Tissue, Skin, B, Sremska Kamenica, Vojvodina
University Clinical Center of Kragujevac, Center for Internal Oncology, Kragujevac, Šumadijski Okrug
Chris Hani Baragwanath Academic Hospital, Johannesburg, Gauteng
The Medical Oncology Centre of Rosebank, Johannesburg, Gauteng
Wits Clinical Research, Parktown, Johannesburg, Gauteng
Steve Biko Academic Hospital, Pretoria, Gauteng
Curo Oncology, Pretoria, Gauteng
Little Company Of Mary Hospital - Oncology, Pretoria, Gauteng
Rainbow Oncology Centre, Durban, Kwazulu-Natal
Cape Gate Oncology Centre, Bellville, Western Cape
Cancercare - Rondebosch Oncology, Cape Town, Western Cape
Hospital Universitario Virgen de la Macarena - Oncología Médica, Sevilla, Andalucía
Institut Català d'Oncologia-Hospital Universitari Germans Trias i Pujol - Oncología Médica, Badalona, Barcelona
Hospital San Pedro de Alcántara - Oncología, Caceres, Cáceres
H.U.V.Arrixaca, El Palmar, Murcia, Región De
Hospital Universitario Vall d'Hebron - Oncología Médica, Barcelona, Not set
Hospital de la Santa Creu i Sant Pau - Oncología Médica, Barcelona, Not set
M.D. Anderson Center Madrid, Madrid, Not set
Hospital Regional Universitario de Malaga - Servicio de Oncología, Málaga, Not set
Hospital HLA Jerez Puerta Sur, Sevilla, Not set
Consorcio Hospital General Universitario de Valencia - Oncología, Valencia, Not set
China Medical University Hospital - Internal Medicine, Taichung, Taichung Municipality
Taipei Medical University - Shuang Ho Hospital Ministry of Health and Welfare, New Taipei City, Taipei
Changhua Christian Medical Foundation - Changhua Christian Hospital - Internal Medicine, Changhua, Not set
Taipei Municipal Wanfang Hospital - Managed by Taipei Medical University - Hematology and Oncology, Taipei, Not set
Maharaj Nakorn Chiangmai Hospital - Medical Oncology, Chiangmai, Chiang Mai
Khon Kaen University, Srinagarind Hospital - Academic Clinical Research Office (ACRO), Khonkaen, Khon Kaen
King Chulalongkorn Memorial Hospital [Medical Oncology], Bangkok, Krung Thep Maha Nakhon [Bangko
Ramathibodi Hospital - Immunology and Rheumatology, Bangkok, Krung Thep Maha Nakhon [Bangko
Siriraj Hospital - Medical Oncology, Bangkok, Krung Thep Maha Nakhon [Bangko
Prince of Songkla University, Songkla, Songkhla
Gazi University Medical Faculty - Gynecology, Yenimahalle/Ankara, Ankara
Koc Universitesi Hastanesi; Tıbbi Onkoloji, Istanbul, Antalya
Adana City Training and Research Hospital, Adana, Not set
Gulhane Training and Research Hospital - Medical Oncology, Ankara, Not set
Ankara University Medical Faculty, Ankara, Not set
Ankara Liv Hospital, Ankara, Not set
Memorial Ankara Hastanesi, Ankara, Not set
Dr Abdurrahman Yurtaslan Training and Research Hospital - Medical Oncology, Ankara, Not set
Uludag University Medical Faculty, Bursa, Not set
Medical Point Gaziantep Hospital, Gaziantep, Not set
Gaziantep University Sahinbey Practise and Research Hospital - Internal Medicine- Endocrinology and, Gaziantep, Not set
Bakirkoy Dr. Sadi Konuk Egt. Ars Hast., Istanbul, Not set
Goztepe SuleymanYalcin Sehir Hast, Istanbul, Not set
Memorial Bahçelievler Hospital, Istanbul, Not set
Izmir Medical Point Hastanesi, Izmir, Not set
Kocaeli University Research and Practice Hospital - Medical Oncology, Kocaeli, Not set
Necmettin Erbakan University Meram Medical Faculty - Oncology, Konya, Not set
Sakarya Training and Research Hospital, Sakarya, Not set
VM Medical Park Samsun Hospital - Medical oncology, Samsun, Not set
ARENSIA Exploratory Medicine LLC, Kyiv, Kyïv
Hanoi Oncology Hospital, Hanoi, Ha Noi, Thu Do
Vietnam National Cancer Hopsital, Hanoi, Ha Noi, Thu Do
HCM Oncology Hospital - Medical Oncology, Ho Chi Minh, Ho Chi Minh, Thanh Pho [Sai Go
Conditions: Melanoma
Study to Evaluate Tulisokibart for Hidradenitis Suppurativa (MK-7240-012)
Recruiting
This is a phase 2b randomized, double-blind, placebo-controlled study of the safety and efficacy of tulisokibart in participants with moderate to severe hidradenitis suppurativa. The primary hypothesis is that at least 1 dose of tulisokibart is superior to placebo with respect to the proportion of participants achieving a 50% reduction in Hidradenitis Suppurativa Clinical Response (HiSCR50) at Week 16 (ie, at end of double-blind treatment).
This is a phase 2b randomized, double-blind, placebo-controlled study of the safety and efficacy of tulisokibart in participants with moderate to severe hidradenitis suppurativa. The primary hypothesis is that at least 1 dose of tulisokibart is superior to placebo with respect to the proportion of participants achieving a 50% reduction in Hidradenitis Suppurativa Clinical Response (HiSCR50) at Week 16 (ie, at end of double-blind treatment). Read Less
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
08/13/2025
Locations: Cahaba Dermatology & Skin Health Center ( Site 0012), Birmingham, Alabama +20 locations
Cahaba Dermatology & Skin Health Center ( Site 0012), Birmingham, Alabama
Medical Dermatology Specialists ( Site 0027), Phoenix, Arizona
Northridge Clinical Trials ( Site 0004), Northridge, California
Integrative Skin Science and Research ( Site 0015), Sacramento, California
Skin Care Physicians of Georgia ( Site 0033), Macon, Georgia
Dawes Fretzin Clinical Research Group, LLC ( Site 0025), Indianapolis, Indiana
Revival Research Institute, LLC ( Site 0005), Troy, Michigan
DJL Clinical Research, PLLC ( Site 0021), Charlotte, North Carolina
Wright State Physicians Health Center ( Site 0041), Fairborn, Ohio
Palmetto Clinical Trial Services, LLC ( Site 0023), Anderson, South Carolina
Arlington Center for Dermatology ( Site 0045), Arlington, Texas
Texas Dermatology Research Center ( Site 0019), Dallas, Texas
Reveal Research Institute ( Site 0018), Frisco, Texas
Progressive Clinical Research ( Site 0020), San Antonio, Texas
Fremantle Dermatology ( Site 1402), Fremantle, Western Australia
York Dermatology Clinic & Research Centre ( Site 0106), Richmond Hill, Ontario
The Second Xiangya Hospital of Central South University ( Site 1505), Changsha, Hunan
Huashan Hospital of Fudan University ( Site 1506), Shanghai, Shanghai
Medical Corporation Kojinkai Sapporo Skin Clinic ( Site 1606), Sapporo, Hokkaido
University of the Ryukyus Hospital ( Site 1601), Ginowan, Okinawa
University Hospital,Kyoto Prefectural University of Medicine ( Site 1605), Kyoto, Not set
Conditions: Hidradenitis Suppurativa
A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)
Recruiting
The goal of this study is to evaluate intismeran autogene plus pembrolizumab versus placebo plus pembrolizumab for the adjuvant treatment of margin negative, completely resected Stage II, IIIA, IIIB (with nodal involvement \[N2\]) non-small cell lung cancer (NSCLC). The primary hypothesis is that intismeran autogene plus pembrolizumab is superior to placebo plus pembrolizumab with respect to disease-free survival (DFS) as assessed by the investigator.
The goal of this study is to evaluate intismeran autogene plus pembrolizumab versus placebo plus pembrolizumab for the adjuvant treatment of margin negative, completely resected Stage II, IIIA, IIIB (with nodal involvement \[N2\]) non-small cell lung cancer (NSCLC). The primary hypothesis is that intismeran autogene plus pembrolizumab is superior to placebo plus pembrolizumab with respect to disease-free survival (DFS) as assessed by the investigator. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/13/2025
Locations: Alaska Oncology and Hematology ( Site 0039), Anchorage, Alaska +198 locations
Alaska Oncology and Hematology ( Site 0039), Anchorage, Alaska
The University of Arizona Cancer Center - North Campus ( Site 0071), Tucson, Arizona
YUMA REGIONAL MEDICAL CENTER CANCER CENTER ( Site 0020), Yuma, Arizona
UCLA Clinical & Translational Research Center (CTRC) ( Site 0059), Los Angeles, California
St. Joseph Hospital-The Center for Cancer Prevention and Treatment ( Site 0074), Orange, California
University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 0030), Orange, California
UCHealth Memorial Hospital-Heme Onc ( Site 0052), Colorado Springs, Colorado
Mayo Clinic Florida ( Site 4043), Jacksonville, Florida
Mid Florida Hematology and Oncology Center ( Site 0014), Orange City, Florida
AdventHealth Orlando-AdventHealth Medical Group Hematology & Oncology at Orlandoc ( Site 0013), Orlando, Florida
Moffitt Cancer Center ( Site 0078), Tampa, Florida
Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital ( Site 0012), Marietta, Georgia
Southeastern Regional Medical Center ( Site 0098), Newnan, Georgia
Beacon Cancer Care ( Site 0044), Post Falls, Idaho
University of Iowa-Holden Comprehensive Cancer Center ( Site 0062), Iowa City, Iowa
Saint Elizabeth Healthcare ( Site 0092), Edgewood, Kentucky
The University of Louisville, James Graham Brown Cancer Center ( Site 0037), Louisville, Kentucky
University of Michigan Clinical Trials Office ( Site 0058), Ann Arbor, Michigan
Cancer and Hematology Centers of Western Michigan ( Site 4003), Grand Rapids, Michigan
St. Vincent Frontier Cancer Center ( Site 0043), Billings, Montana
NHO Revive Research Institute, LLC ( Site 4009), Lincoln, Nebraska
John Theurer Cancer Center at Hackensack University Medical Center ( Site 0036), Hackensack, New Jersey
Atlantic Health Morristown Medical Center ( Site 4018), Morristown, New Jersey
New York Oncology Hematology, P.C. ( Site 4012), Albany, New York
Montefiore Medical Center- Montefiore Medical Park-Oncology ( Site 0080), Bronx, New York
Perlmutter Cancer Center at NYU Langone Hospital - Long Island-Clinical Research Department ( Site 0095), Mineola, New York
Laura and Isaac Perlmutter Cancer Center ( Site 0010), New York, New York
Icahn School of Medicine at Mount Sinai ( Site 0034), New York, New York
Columbia University Irving Medical Center-CUIMC Herbert Irving Comprehensive Cancer Center Clinical ( Site 0054), New York, New York
Memorial Sloan Kettering Cancer Center ( Site 0029), New York, New York
Stony Brook University-Cancer Center ( Site 0072), Stony Brook, New York
Sanford Fargo Medical Center-Roger Maris Cancer Center ( Site 0063), Fargo, North Dakota
Altru Health System ( Site 0040), Grand Forks, North Dakota
Summa Health ( Site 4011), Akron, Ohio
University of Cincinnati Medical Center-University of Cincinnati Cancer Center ( Site 0028), Cincinnati, Ohio
University Hospitals Cleveland Medical Center ( Site 0023), Cleveland, Ohio
OSU Brain and Spine Hospital ( Site 0016), Columbus, Ohio
Good Samaritan Regional Medical Center-Samaritan Pastega Regional Cancer Center ( Site 0082), Corvallis, Oregon
Thomas Jefferson University - Clinical Research Institute ( Site 0006), Philadelphia, Pennsylvania
Medical University of South Carolina-Hollings Cancer Center ( Site 0050), Charleston, South Carolina
Sanford Cancer Center ( Site 0075), Sioux Falls, South Dakota
Thompson Cancer Survival Center ( Site 0097), Knoxville, Tennessee
One Oncology - Tennessee Oncology ( Site 4019), Nashville, Tennessee
SCRI Oncology Partners ( Site 7001), Nashville, Tennessee
UT Southwestern Medical Center ( Site 0061), Dallas, Texas
Inova Schar Cancer Institute ( Site 0003), Fairfax, Virginia
Swedish Medical Center-Swedish Cancer Institute ( Site 0088), Seattle, Washington
Fred Hutchinson Cancer Center ( Site 0002), Seattle, Washington
Edwards Comprehensive Cancer Center ( Site 4015), Huntington, West Virginia
Clinica Adventista Belgrano-Oncology ( Site 2901), Caba., Buenos Aires
Hospital Italiano de Buenos Aires-Clinical Oncology ( Site 2912), Ciudad Autonoma de Buenos Aires, Buenos Aires
Instituto Alexander Fleming ( Site 2911), Ciudad Autónoma de Buenos Aires, Buenos Aires
Instituto de Investigaciones Clínicas Mar del Plata ( Site 2908), Mar del Plata, Buenos Aires
Fundacion Estudios Clinicos-Oncology ( Site 2907), Rosario, Santa Fe
Sanatorio Parque ( Site 2904), Rosario, Santa Fe
Peter MacCallum Cancer Centre-Parkville Cancer Clinical Trials Unit (PCCTU) ( Site 0203), Melbourne, Victoria
St Vincent's Hospital-Oncology Clinical Trials ( Site 0202), Melbourne, Victoria
One Clinical Research ( Site 0200), Nedlands, Western Australia
Antwerp University Hospital-Thoracic Oncology ( Site 0603), Edegem, Antwerpen
Université Catholique de Louvain-Namur - Centre Hospitalier Universitaire Dinant-Godinne - Site Godi ( Site 0602), Yvoir, Namur
AZORG Campus Aalst-Moorselbaan ( Site 0604), Aalst, Oost-Vlaanderen
VITAZ ( Site 0600), Sint-Niklaas, Oost-Vlaanderen
CRIO - CENTRO REGIONAL INTEGRADO DE ONCOLOGIA-Pesquisa Clínica ( Site 3007), Fortaleza, Ceara
Liga Norte Riograndense Contra o Câncer ( Site 3001), Natal., Rio Grande Do Norte
Irmandade da Santa Casa de Misericórdia de Porto Alegre ( Site 3003), Porto Alegre, Rio Grande Do Sul
Hospital Nossa Senhora da Conceição ( Site 3002), Porto Alegre, Rio Grande Do Sul
Fundação Pio XII - Hospital de Câncer de Barretos ( Site 3004), Barretos, Sao Paulo
Fundação Faculdade Regional de Medicina de São José do Rio Preto ( Site 3013), São José do Rio Preto, Sao Paulo
Instituto Nacional de Câncer - INCA ( Site 3000), Rio de Janeiro, Not set
Hospital Samaritano De Sao Paulo ( Site 3006), Sao Paulo, Not set
ICESP - INSTITUTO DO CÂNCER DO ESTADO DE SÃO PAULO ( Site 3005), Sao Paulo, Not set
Cross Cancer Institute ( Site 0105), Edmonton, Alberta
William Osler Health System ( Site 0101), Brampton, Ontario
Princess Margaret Cancer Centre ( Site 0102), Toronto, Ontario
Centre Hospitalier de l'Université de Montréal ( Site 0104), Montréal, Quebec
McGill University Health Centre ( Site 0100), Montréal, Quebec
Orlandi Oncologia-Oncology ( Site 3102), Santiago, Region M. De Santiago
FALP-UIDO ( Site 3100), Santiago, Region M. De Santiago
Pontificia Universidad Catolica de Chile ( Site 3104), Santiago, Region M. De Santiago
Bradfordhill-Clinical Area ( Site 3103), Santiago, Region M. De Santiago
ONCOCENTRO APYS ( Site 3105), Viña del Mar, Valparaiso
CIMCA ( Site 3300), San José, San Jose
ICIMED ( Site 3301), San Jose, Not set
Masarykuv onkologicky ustav-Klinika komplexni onkologicke pece ( Site 0700), Brno, Brno-mesto
Nemocnice AGEL Ostrava - Vitkovice a.s.-Plicni odd ( Site 0702), Ostrava, Ostrava Mesto
Fakultni nemocnice Olomouc-Klinika plicnich nemoci a tuberkulozy ( Site 0701), Olomouc, Not set
Vseobecna fakultni nemocnice v Praze ( Site 0703), Praha 2, Not set
Rigshospitalet ( Site 0801), Copenhagen, Hovedstaden
Odense Universitetshospital ( Site 0800), Odense C, Syddanmark
North Estonia Medical Centre Foundation-Chemotherapy ( Site 0901), Tallinn, Harjumaa
Tartu University Hospital-Radiotherapy and oncology ( Site 0900), Tartu, Tartumaa
Tampereen yliopistollinen sairaala-Oncology ( Site 1001), Tampere, Pirkanmaa
Vaasan Keskussairaala-Department of Clinical Oncology ( Site 1004), Vaasa, Pohjanmaa
Oulun yliopistollinen sairaala-Oncology and Hematology ( Site 1003), Oulu, Pohjois-Pohjanmaa
Turku University Hospital-The Department of Pulmonary Medicine ( Site 1000), Turku, Varsinais-Suomi
Nouvel Hôpital Civil (NHC)-Service de pneumologie ( Site 1100), Strasbourg, Alsace
CHU Bordeaux Haut-Leveque ( Site 1106), Pessac, Aquitaine
Assistance Publique Hôpitaux de Marseille - Hôpital Nord ( Site 1108), Marseille, Bouches-du-Rhone
Centre Hospitalier Universitaire de Caen - Hôpital Côte de Nacre ( Site 1107), Caen, Calvados
Hôpital Arnaud de Villeneuve - CHU Montpellier ( Site 1102), Montpellier, Herault
Institut de Cancérologie de l'Ouest ( Site 1101), ANGERS cedex 02, Maine-et-Loire
CHU GABRIEL MONTPIED ( Site 1105), Clermont-Ferrand, Puy-de-Dome
Hopitaux Universitaires Paris Centre-Hopital Cochin ( Site 1104), Paris, Not set
Klinikum Esslingen-Klinik für Kardiologie und Pneumologie ( Site 1201), Esslingen, Baden-Wurttemberg
Asklepios Klinik Gauting GmbH-Oncology ( Site 1209), Gauting, Bayern
Klinikverbund Allgäu gGmbH ( Site 1205), Kempten, Bayern
Universitaetsklinikum Regensburg ( Site 1204), Regensburg, Bayern
Augusta-Kranken-Anstalt ( Site 1213), Bochum, Nordrhein-Westfalen
Gemeinschaftspraxis für Hämatologie und Onkologie Münster ( Site 1202), Münster, Nordrhein-Westfalen
Brüderkrankenhaus St. Josef Paderborn-Klinik für Hämatologie und Onkologie ( Site 1214), Paderborn, Nordrhein-Westfalen
SRH Wald-Klinikum Gera-Lungenkrebszentrum ( Site 1200), Gera, Thuringen
Helios Klinikum Emil von Behring Berlin-Zehlendorf-Lungenklinik Heckeshorn ( Site 1208), Berlin, Not set
Errikos Dunant Hospital Center-Fourth Department of Oncology and Clinical Trials Unit ( Site 1301), Athens, Attiki
THORACIC GENERAL HOSPITAL OF ATHENS "I SOTIRIA"-3rd Dept of Internal Medicine and Laboratory, Oncol ( Site 1300), Athens, Attiki
European Interbalkan Medical Center-Oncology Department ( Site 1302), Thessaloniki, Not set
Bacs-Kiskun Varmegyei Oktatokorhaz-Onkoradiologiai Kozpont ( Site 1401), Kecskemét, Bacs-Kiskun
Pécsi Tudományegyetem Klinikai Központ-Onkoterápiás Intézet ( Site 1402), Pecs, Baranya
Gyor-Moson-Sopron Varmegyei Petz Aladar Egyetemi Oktato Korhaz - Pulmonologia Osztaly ( Site 1404), Gyor, Gyor-Moson-Sopron
Reformatus Pulmonologiai Centrum ( Site 1405), Törökbálint, Pest
Somogy Varmegyei Kaposi Mor Oktato Korhaz -Onkologiai Kozpont ( Site 1407), Kaposvár, Somogy
Tallaght University Hospital ( Site 3903), Dublin, Not set
CRO-IRCCS-Clinical Oncology ( Site 1510), Aviano, Friuli-Venezia Giulia
P.O. "S. Maria della Misericordia" Azienda Sanitaria Univers-Oncology Department ( Site 1506), Udine, Friuli-Venezia Giulia
Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 1504), Milan, Lombardia
ASST Grande Ospedale Metropolitano Niguarda-Oncologia Falck ( Site 1511), Milan, Milano
A.O.R.N. Ospedale dei Colli - Monaldi V.-U.O.C Pneumologia Oncologica DH PNL ONC ( Site 1508), Naples, Napoli
Instituto Tumori Giovanni Paolo II-SSD Oncologia Medica per la Patologia Toracica ( Site 1507), Bari, Puglia
POLICLINICO "G. RODOLICO"-UOC Oncologia Medica ( Site 1503), Catania, Sicilia
AO Santa Maria della Misericordia-Oncology Department ( Site 1501), Perugia, Umbria
Azienda Ospedaliera Santa Croce e Carle ( Site 1500), Cuneo, Not set
Azienda Ospedaliero Universitaria Maggiore della Carità ( Site 1502), Novara, Not set
National Cancer Center Hospital East ( Site 3800), Kashiwa, Chiba
St. Marianna University Hospital ( Site 3802), Kawasaki, Kanagawa
Kanagawa Cancer Center ( Site 3801), Yokohama, Kanagawa
Kansai Medical University Hospital ( Site 3806), Hirakata, Osaka
Kindai University Hospital ( Site 3803), Osakasayama, Osaka
Hiroshima University Hospital ( Site 3804), Hiroshima, Not set
Chungbuk National University Hospital-Internal medicine ( Site 0402), Cheongju-si, Chungbuk
National Cancer Center-Lung Cancer Center ( Site 0403), Goyang-si, Kyonggi-do
Seoul National University Bundang Hospital-Medical Oncology ( Site 0404), Seongnam, Kyonggi-do
The Catholic University Of Korea St. Vincent's Hospital-Medical Oncology ( Site 0406), Suwon-si, Kyonggi-do
Keimyung University Dongsan Hospital CRC room 1 ( Site 0407), Daegu, Taegu-Kwangyokshi
Seoul National University Hospital ( Site 0400), Seoul, Not set
Asan Medical Center-Department of Oncology ( Site 0405), Seoul, Not set
Samsung Medical Center ( Site 0401), Seoul, Not set
RIGA EAST UNIVERSITY HOSPITAL ,Oncology Centre of Latvia ( Site 1600), Riga, Not set
Hospital of Lithuanian University of Health Sciences Kauno klinikos-Pulmonology ( Site 1701), Kaunas, Kauno Apskritis
National Cancer Institute-Department of Thoracic Surgery and Oncology ( Site 1700), Vilnius, Vilniaus Miestas
University Malaya Medical Centre ( Site 3502), Lembah Pantai, Kuala Lumpur
National Cancer Institute-Radiotherapy and Oncology ( Site 3506), Putrajaya, Kuala Lumpur
Hospital Tengku Ampuan Afzan ( Site 3504), Kuantan, Pahang
Hospital Pulau Pinang ( Site 3505), George Town, Pulau Pinang
Sarawak General Hospital ( Site 3500), Kuching, Sarawak
CIO - Centro de Inmuno-Oncología de Occidente ( Site 3403), Guadalajara, Jalisco
Hospital Universitario "Dr. Jose Eleuterio Gonzalez"-Hematologia and Oncologia ( Site 3408), Monterrey, Nuevo Leon
Unidad de Mastologia Avanzada de Chihuahua S.A de C.V ( Site 3402), Chihuahua, Not set
Mediadvance Clinical ( Site 3404), Chihuahua, Not set
Oaxaca Site Management Organization S.C. ( Site 3407), Oaxaca, Not set
Centro de Investigacion Clinica de Oaxaca ( Site 3401), Oaxaca, Not set
New Zealand Clinical Research (Christchurch) ( Site 0300), Christchurch, Canterbury
Harbour Cancer & Wellness ( Site 0301), Auckland, Not set
Akershus Universitetssykehus-Avdeling for lungesykdommer ( Site 1900), Lørenskog, Akershus
Drammen Sykehus, Vestre Viken HF ( Site 1903), Drammen, Buskerud
Stavanger Universitetssykehus ( Site 1901), Stavanger, Rogaland
Metro Davao Medical and Research Center ( Site 3602), Davao City, Davao Del Sur
ST. LUKE'S MEDICAL CENTER ( Site 3606), Quezon City, National Capital Region
CARDINAL SANTOS MEDICAL CENTER-Research Room ( Site 3601), San Juan City, Metro Manila, National Capital Region
Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 2003), Bydgoszcz, Kujawsko-pomorskie
Krakowski Szpital Specjalistyczny im. Jana Pawła II-Oddział Kliniczny Chirurgii Klatki Piersiowej i ( Site 2011), Krakow, Malopolskie
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworow Pluca i Klatki Pier ( Site 2000), Warszawa, Mazowieckie
Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 2001), Przemysl, Podkarpackie
Bialostockie Centrum Onkologii ( Site 2005), Bialystok, Podlaskie
Uniwersyteckie Centrum Kliniczne ( Site 2013), Gdansk, Pomorskie
Warmińsko - Mazurskie Centrum Chorób Płuc w Olsztynie-Oddzial Onkologii z Pododdzialem Chemioterapii ( Site 2008), Olsztyn, Warminsko-mazurskie
Wielkopolskie Centrum Pulmonologii i Torakochirurgii-Oddzial Onkologii Klinicznej z Pododdzialem Dz ( Site 2002), Poznan, Wielkopolskie
Unidade Local de Saude de Santa Maria - Hospital Pulido Valente ( Site 2703), Lisbon, Lisboa
Instituto Português de Oncologia do Porto Francisco Gentil, EPE ( Site 2702), Porto, Not set
Fakultna nemocnica s poliklinikou F.D.Roosevelta Banska Bystrica ( Site 2202), Banska Bystrica, Banskobystricky Kraj
Univerzitná nemocnica Bratislava - Nemocnica Ružinov ( Site 2201), Bratislava, Bratislavsky Kraj
Institut Català d'Oncologia - L'Hospitalet-Medical Oncology ( Site 2401), L'Hospitalet de Llobregat, Barcelona
HOSPITAL UNIVERSITARIO PUERTA DE HIERRO MAJADAHONDA-Medical Oncology ( Site 2403), Majadahonda, Madrid, Comunidad De
HOSPITAL UNIVERSITARIO QUIRONSALUD MADRID-ONCOLOGIA MEDICA ( Site 2402), Pozuelo de Alarcon, Madrid
Hospital Quirón Málaga ( Site 2405), Málaga, Malaga
Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 2400), Barcelona, Not set
Hospital Universitario Virgen Macarena-Unidad de Investigación Oncológica ( Site 2404), Sevilla, Not set
National Taiwan University Cancer Center (NTUCC) ( Site 0500), Taipei City, Taipei
Changhua Christian Hospital ( Site 0504), Changhua, Not set
National Taiwan University Hospital - Hsinchu branch ( Site 0501), Hsinchu, Not set
Taichung Veterans General Hospital-Chest ( Site 0503), Taichung, Not set
National Cheng Kung University Hospital-Clinical Trial Center ( Site 0505), Tainan, Not set
National Taiwan University Hospital-Oncology ( Site 0506), Taipei, Not set
Taipei Medical University Hospital ( Site 0502), Taipei, Not set
Medipol Mega Universite Hastanesi-oncology ( Site 2105), Stanbul, Istanbul
Ege Universitesi Hastanesi-Chest Diseases Department ( Site 2107), Bornova, Izmir
Hacettepe Universite Hastaneleri-oncology hospital ( Site 2100), Ankara, Not set
Memorial Ankara Hastanesi-Medical Oncology ( Site 2103), Ankara, Not set
Liv Hospital Ankara-Oncology ( Site 2104), Ankara, Not set
Ankara Bilkent Şehir Hastanesi-Medical Oncology ( Site 2101), Ankara, Not set
TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 2102), Istanbul, Not set
Conditions: Non-small Cell Lung Cancer
A Clinical Study of PGN-EDODM1 in People With Myotonic Dystrophy Type 1
Recruiting
The purpose of this study is to learn about the effects of an investigational medicine, PGN-EDODM1, to see how safe and tolerable multiple administrations of PGN-EDODM1 are for people with myotonic dystrophy type 1 (DM1) compared to placebo.
The purpose of this study is to learn about the effects of an investigational medicine, PGN-EDODM1, to see how safe and tolerable multiple administrations of PGN-EDODM1 are for people with myotonic dystrophy type 1 (DM1) compared to placebo. Read Less
Gender:
ALL
Ages:
Between 16 years and 60 years
Trial Updated:
08/13/2025
Locations: University of Calgary, Calgary, Alberta +5 locations
University of Calgary, Calgary, Alberta
Ottawa Hospital Research Institute (OHRI), Ottawa, Ontario
CIUSSS du Saguenay-Lac-Saint-Jean, Chicoutimi, Quebec
Montreal Neurological Institute, Montréal, Quebec
University College London Hospitals NHS Foundation Trust, London, UK
Newcastle Upon Tyne Hospitals, Newcastle Upon Tyne, Not set
Conditions: Myotonic Dystrophy 1
Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation
Recruiting
This is a multicenter, randomized, open-label, Phase 3 study in participants with newly diagnosed multiple myeloma to evaluate the benefits of teclistamab in combination with lenalidomide and teclistamab alone versus lenalidomide alone as maintenance therapy after autologous stem cell transplant.
This is a multicenter, randomized, open-label, Phase 3 study in participants with newly diagnosed multiple myeloma to evaluate the benefits of teclistamab in combination with lenalidomide and teclistamab alone versus lenalidomide alone as maintenance therapy after autologous stem cell transplant. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/13/2025
Locations: The University of Arizona Cancer Center, Phoenix, Arizona +207 locations
The University of Arizona Cancer Center, Phoenix, Arizona
University of California-Davis Cancer Center, Sacramento, California
University of California, San Diego (UCSD) Medical Center, San Diego, California
University of Colorado Hospital, Aurora, Colorado
Colorado Blood Cancer Institute, Denver, Colorado
Yale New Haven Hospital, New Haven, Connecticut
Christiana Care, Newark, Delaware
Blood & Marrow Transplant Center, Florida Hospital Medical Group, Orlando, Florida
Moffitt at Memorial Healthcare System, Tampa, Florida
University of Illinois Medical Center at Chicago, Chicago, Illinois
Greenebaum Cancer Center UM of MD, Baltimore, Maryland
John Hopkins, Baltimore, Maryland
Tufts Medical Center, Boston, Massachusetts
Beth Israel Deaconess Medical Center, Boston, Massachusetts
Karmanos Cancer Institute, Detroit, Michigan
Montefiore Medical Cente, Bronx, New York
Mount Sinai Medical Center - 2, New York, New York
Levine Cancer Institute, Charlotte, North Carolina
Duke University, Durham, North Carolina
East Carolina University, Greenville, North Carolina
University of Cincinnati, Cincinnati, Ohio
Seidman Cancer Center-University Hospitals Cleveland Medical Center, Cleveland, Ohio
Ohio State Medical Center, James Cancer Center, Columbus, Ohio
Lehigh Valley Health Network, Allentown, Pennsylvania
Penn State Hershey Medical Center, Hershey, Pennsylvania
Abramson Cancer Center University of Pennsylvania Medical Center, Philadelphia, Pennsylvania
Fox Chase Cancer Center, Philadelphia, Pennsylvania
Medical University of South Carolina (MUSC), Charleston, South Carolina
Gibbs Cancer Center, Spartanburg, South Carolina
Vanderbilt University, Nashville, Tennessee
Baylor College of Medicine Center for Cell and Gene Therapy, Houston, Texas
LDS Hospital/ Intermountain Healthcare, Salt Lake City, Utah
Virginia Oncology Associates, Norfolk, Virginia
St Vincent HSHS (Green Bay Oncology), Green Bay, Wisconsin
University of Wisconsin Hospital and Clinics, Madison, Wisconsin
Froedtert Memorial Lutheran Hospital, Milwaukee, Wisconsin
Hospital Italiano, Buenos Aires, Not set
Hospital Privado, Córdoba, Not set
Sanatorio Britanico Rosario, Rosario, Not set
Sunshine Coast Health, Birtinya, Queensland
Flinders Medical Centre, Adelaide, Not set
Townsville University Hospital, Douglas, Not set
Barwon Health University Hospital Geelong Andrew Love Cancer Centre, Geelong, Not set
Alfred Hospital, Melbourne, Not set
Austin Health, Melbourne, Not set
Calvary Mater Hospital, Newcastle, Not set
Sunshine Coast Health, Sunshine Coast, Not set
Concord Repatriation General Hospital, Sydney, Not set
Royal North Shore Hospital, Sydney, Not set
Landeskrankenhaus, Feldkirch, Feldkirch, Not set
Medizinische Universitaet Innsbruck, Innsbruck, Not set
University Hospital Krems/Donau, Krems, Not set
Kepler Universitätsklinikum Med Campus III, Linz, Not set
Ordensklinikum Linz GmbH, Linz, Not set
Uniklinikum Salzburg, Salzburg, Not set
Clinic Ottakring, Vienna, Not set
LKH Hochsteiermark, Vienna, Not set
Jessa Ziekenhuis, Hasselt, Not set
Department of Hematology, CH Jolimont, La Louvière, Not set
Algemeen Ziekenhuis Delta, Leuven, Not set
University Hospital Leuven, Leuven, Not set
Centre hospitalier universitaire de Liege, Liège, Not set
Hospital Mãe de Deus - Centro Integrado de Oncologia, Porto Alegre, Not set
Hospital Santa Rita, Porto Alegre, Not set
Instituto Americas de Ensino,Pesquisa e Inovação, Rio de Janeiro, Not set
IDOR- Instituto D'or de pesquisa. Av. São Rafael, Salvador, Not set
A Real e Benemérita Associação Portuguesa de Beneficência, São Paulo, Not set
Clínica Medica São Germano,Grupo Oncoclínicas Pesquisa Clínica, São Paulo, Not set
Departamento de Oncologia Clínica AC Camargo Cancer Center, São Paulo, Not set
Grupo Oncoclínicas Pesquisa Clínica, São Paulo, Not set
Hcor, Associacao Siria, São Paulo, Not set
Hemocentro UNICAMP, Universidade Estadual de Campinas, São Paulo, Not set
Hospital das Clínicas da Universidade de São Paulo, São Paulo, Not set
Hospital Paulistano, Centro de Pesquisa Clinica R. Martiniano de Carvalho, São Paulo, Not set
Onco Star, São Paulo, Not set
Universidade Federal de São Paulo - Hospital São Paulo, São Paulo, Not set
Cross Cancer Institute, Edmonton, Not set
QEII Health Sciences Centre, Halifax, Not set
The Ottawa General Hospital, Ottawa, Not set
Saskatoon Cancer Center, Saskatoon, Not set
"Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Universitaire de Sherbrooke (CIUSSS de l'Estrie - CHUS)", Sherbrooke, Not set
Princess Margaret Cancer Centre, Toronto, Not set
BC Cancer, Vancouver, Not set
Beijing Chaoyang Hospital, Beijing, Not set
Peking University First Hospital, Beijing, Not set
North China University of Science and Technology Affiliated Hospital.Hematology Department, Hebei, Not set
Henan Cancer Hospital, Henan, Not set
Shandong Qilu Hospital, Shandong, Not set
Shanghai Fourth People's Hospital, Shanghai, Not set
Shenyang City, Liaoning Province, Hematology department, Shenyang, Not set
Institute of Hematology & Blood Disease Hospital Chinese Academy of Medical Science, Tianjin, Not set
The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Not set
Tongji Hospital, Tongji Medical College of Hust, Wuhan, Not set
The First Affiliated Hospital, Zhejiang University College of Medicine, Zhejiang, Not set
Fakultni Nemocnice Hradec Kralove, Hradec Králové, Not set
University Hospital Olomouc, Olomouc, Not set
Fakultni Nemocnice Ostrava, Ostrava, Not set
Fakultni Nemocnice Plzen, Plzen, Not set
Vseobecna Fakultni Nemocnice V Praze, Praha, Not set
Aarhus Universitetshospital, Aarhus, Not set
Rigshospitalet, Copenhagen, Not set
Odense University Hospital, Odense, Not set
Lillebaelt Hospital, Vejle, Not set
Centre Hospitalier Universitaire De Bordeaux, Bordeaux, Not set
Department of Hematology, CHU Lille, Lille, Not set
Institut Paoli Calmettes, Marseille, Not set
Centre Hospitalier Universitaire De Montpellier, Montpellier, Not set
Centre Hospitalier Universitaire De Nantes, Nantes, Not set
Hopital Saint Louis, Paris, Not set
Hôpital Saint-Antoine, Paris, Not set
Centre Hospitalier Universitaire De Poitiers, Poitiers, Not set
Centre Hospitalier Universitaire De Toulouse, Toulouse, Not set
University Medical Center Hamburg-Eppendorf, Hamburg, Not set
Universitaetsklinikum Heidelberg AöR, Heidelberg, Not set
Universitaetsklinikum Jena KöR, Jena, Not set
Universitaetsklinikum Schleswig-Holstein AöR, Lübeck, Not set
Klinikum rechts der Isar der TU Muenchen AöR, München, Not set
Klinikum Nuernberg, Nürnberg, Not set
Universitaetsklinikum Tuebingen AöR, Tübingen, Not set
University Hospital of Würzburg, Würzburg, Not set
University General Hospital Of Alexandroupoli, Alexandroupolis, Not set
Evaggelismos Hospital, Athens, Not set
Regional General Hospital Alexandra, Athens, Not set
Theageneio Cancer Hospital, Thessaloníki, Not set
Cork University Hospital, Cork, Not set
Beaumont Hospital, Dublin, Not set
St James's Hospital, Dublin, Not set
St Vincent's University Hospital, Dublin, Not set
University Hospital Galway, Galway, Not set
University Hospital Limerick, Limerick, Not set
The Barzilai Medical Center, Be'er Sheva, Not set
Health Care Campus, Haifa, Not set
Hadassah Medical Center, Jerusalem, Not set
Beilinson Hospital, Petah tikva, Not set
Chaim Sheba Medical Center, Ramat Gan, Not set
Tel-Aviv Sourasky Medical Center, Tel Aviv, Not set
Azienda Sanitaria Locale Al Di Alessandria, Alessandria, Not set
Azienda Ospedaliero Universitaria Ospedali Riuniti Umberto I G M Lancisi G Salesi, Ancona, Not set
AOU G. Baccelli, Bari, Not set
Policlinico di Bari, Bari, Not set
A.O. Papa Giovanni XXIII, Bergamo, Not set
A.O.U. di Bologna - Policlinico S. Orsola Malpighi, Bologna, Not set
A.O.Spedali Civili di Brescia, Brescia, Not set
Ospedale Oncologico 'A. Businco', Cagliari, Not set
Azienda Ospedaliera-Universitaria Di Cosenza, Cosenza, Not set
Careggi University Hospital, Firenze, Not set
IRCCS Ospedale Policlinico San Martino, Genova, Not set
IRCCS Ospedale Maggiore Policlinico, Milano, Not set
Azienda Ospedaliero Universitaria Di Modena, Modena, Not set
Azienda Ospedaliera Di Rilievo Nazionale Antonio Cardarelli, Napoli, Not set
UOC Oncoematologia, Ospedale Policlinico Federico II, Napoli, Not set
Azienda Ospedaliero-Universitaria Maggiore Della Carita, Novara, Not set
UOC Ematologia - Azienda Ospedale - Università Padova Ospedale Giustinianeo, Padova, Not set
Department of Hematology and Bone Marrow Transplant Centre, Azienda Ospedaliero - Universitaria di Parma, Parma, Not set
Fondazione IRCCS Policlinico San Matteo, Pavia, Not set
Azienda Sanitaria Locale Di Pescara, Pescara, Not set
Ospedale Santa Maria delle Croci, Ravenna, Not set
Azienda USL IRCCS Di Reggio Emilia, Reggio, Not set
Ospedale "Infermi" di Rimini, Rimini, Not set
Ematologia, Azienda Policlinico Umberto I, Roma, Not set
Casa Sollievo Della Sofferenza, San Giovanni Rotondo, Not set
A.O.U. Città della Salute e della Scienza di Torino - SC Ematologia U, Torino, Not set
A.O.U. Ospedali Riuniti di Trieste, Trieste, Not set
Azienda Sanitaria Universitaria Friuli Centrale, Udine, Not set
Chonnam National University Hwasun Hospital, Gwangju, Not set
Department of Oncology, Asan Medical Center, Seoul, Not set
Samsung Medical Center, Seoul, Not set
Seoul National University Hospital, Internal Medicine, Seoul, Not set
Severance Hospital, Seoul, Not set
St. Mary's Hospital, Seoul, Not set
Noordwest Ziekenhuisgroep Stichting, Alkmaar, Not set
Amsterdam University Medical Center, Amsterdam, Not set
Albert Schweitzer Ziekenhuis, Dordrecht, Not set
Maxima Medisch Centrum, Eindhoven, Not set
University Medical Center Groningen, Groningen, Not set
Dijklander Ziekenhuis, Hoorn, Not set
St. Antonius Ziekenhuis, Nieuwegein, Not set
Erasmus University Medical Center Rotterdam, Rotterdam, Not set
Maasstad Ziekenhuis, Rotterdam, Not set
Oslo University Hospital, Oslo, Not set
St. Olavs hospital HF, Trondheim, Not set
Department of Hematology and Transplantology University Clinical Center, Gdańsk, Not set
SPZOZ MSWiA w Poznaniu im. Prof. Ludwika Bierkowskiego, Poznań, Poznań, Not set
Uniwersytecki Szpital Kliniczny, Wrocław, Not set
CCAB Centro Clinico Academico Braga Associacao, Braga, Not set
Champalimaud Clinical Centre, Lisboa, Not set
Instituto Portugues De Oncologia De Lisboa Francisco Gentil E.P.E., Lisboa, Not set
Instituto Portugues De Oncologia Do Porto Francisco Gentil E.P.E., Porto, Not set
Sao Joao University Hospital Center, Porto, Not set
Unidade Local De Saude De Gaia/Espinho E.P.E., Porto, Not set
Unidade Local De Saude De Tras-Os-Montes E Alto Douro E.P.E., Vila Real, Not set
University Clinical Center of Serbia, Belgrade, Not set
Clinical Centre of Kragujevac, Kragujevac, Not set
Clinical Centre of Nis, Niš, Not set
Clinical Centre of Vojvodina, Novi Sad, Not set
University Hospital Basel, Basel, Not set
Inselspital, Bern, Not set
Kantonsspital St. Gallen, Saint Gallen, Not set
Ankara Liv Hospital, Ankara, Not set
Ankara University Hospital, Ankara, Not set
Florence Nightingale Hospital, Istanbul, Not set
Medipol Mega University Hospital, Istanbul, Not set
Ege University Medical faculty Hospital Internal Medicine Department Adult Hematology Unit, İzmir, Not set
Izmir Economy University, Medical Point Hospital, İzmir, Not set
Erciyes University Hospital, Kayseri, Not set
Hammersmith Hospital - Imperial College NHS Healthcare Trust, London, Not set
University College London (UCL), London, Not set
The Royal Marsden Hospital, Sutton, Not set
Conditions: Multiple Myeloma
A Study to Evaluate Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderately to Severely Active Ulcerative Colitis (MK-7240-001)
Recruiting
The purpose of this protocol is to evaluate the efficacy of tulisokibart in participants with moderately to severely active ulcerative colitis. Study 1's primary hypotheses are that at least 1 tulisokibart dose level is superior to Placebo in the proportion of participants achieving clinical remission according to the Modified Mayo Score at Week 12, and that at least 1 tulisokibart dose level is superior to Placebo in the proportion of participants achieving clinical remission according to the M... Read More
The purpose of this protocol is to evaluate the efficacy of tulisokibart in participants with moderately to severely active ulcerative colitis. Study 1's primary hypotheses are that at least 1 tulisokibart dose level is superior to Placebo in the proportion of participants achieving clinical remission according to the Modified Mayo Score at Week 12, and that at least 1 tulisokibart dose level is superior to Placebo in the proportion of participants achieving clinical remission according to the Modified Mayo Score at week 52. Study 2's primary hypothesis is that at least 1 tulisokibart dose level is superior to Placebo in the proportion of participants achieving clinical remission according to the Modified Mayo Score at Week 12. Read Less
Gender:
ALL
Ages:
Between 16 years and 80 years
Trial Updated:
08/13/2025
Locations: Digestive Health Specialists ( Site 0135), Dothan, Alabama +450 locations
Digestive Health Specialists ( Site 0135), Dothan, Alabama
IMC-Gulf Coast Gastroenterology ( Site 0157), Fairhope, Alabama
Research Solutions of Arizona ( Site 3816), Litchfield Park, Arizona
One of a Kind Clinical Research Center ( Site 3852), Scottsdale, Arizona
GI Alliance - Sun City ( Site 0103), Sun City, Arizona
Clinnova Research ( Site 3803), Anaheim, California
Southern California Research Center ( Site 3828), Coronado, California
UCSD - Altman Clinical and Translational Research Institute (ACTRI) ( Site 0113), La Jolla, California
Cedars-Sinai Medical Center ( Site 0119), Los Angeles, California
University of Colorado Anschutz Medical Campus-Division of Gastroenterology and Hepatology ( Site 0172), Aurora, Colorado
Peak Gastroenterology Associates ( Site 0116), Colorado Springs, Colorado
South Denver Gastroenterology, PC ( Site 3849), Englewood, Colorado
Rocky Mountain Gastroenterology/Topography Health ( Site 3838), Littleton, Colorado
Connecticut Clinical Research Institute ( Site 0126), Bristol, Connecticut
Medical Research Center of Connecticut ( Site 0151), Hamden, Connecticut
Yale University School of Medicine-Digestive Disease ( Site 0163), New Haven, Connecticut
Emerson Clinical Research Institute ( Site 3820), Washington, District of Columbia
Gastroenterology Consultants of Clearwater ( Site 0152), Clearwater, Florida
University of Florida College of Medicine-Gastroenterology ( Site 3821), Gainesville, Florida
Nature Coast Clinical Research - Inverness ( Site 3806), Inverness, Florida
Central Florida Gastro Research ( Site 0124), Kissimmee, Florida
Research Associates of South Florida - Miami - Southwest 8th Street ( Site 3810), Miami, Florida
Orlando Health ( Site 0145), Orlando, Florida
USF Health ( Site 0169), Tampa, Florida
Emory University School of Medicine ( Site 3818), Atlanta, Georgia
Atlanta Gastroenterology Associates - Peachtree Dunwoody ( Site 0115), Atlanta, Georgia
Atlanta Center for Gastroenterology ( Site 0155), Decatur, Georgia
University of Chicago Medical Center ( Site 0134), Chicago, Illinois
GI Alliance - Glenview ( Site 0168), Glenview, Illinois
GI ALLIANCE - GURNEE ( Site 0107), Gurnee, Illinois
Iowa Digestive Disease Center ( Site 0123), Clive, Iowa
University of Louisville Hospital-Clinical Trials Unit ( Site 0165), Louisville, Kentucky
Baton Rouge General Medical Center - Bluebonnet ( Site 0112), Baton Rouge, Louisiana
Tulane University School of Medicine-Gastroenterology and Hepatology ( Site 0154), New Orleans, Louisiana
Walter Reed National Military Medical Center ( Site 0121), Bethesda, Maryland
Woodholme Gastroenterology Associates-Woodholme Gastroenterology Associates ( Site 3835), Glen Burnie, Maryland
Massachusetts General Hospital-Crohn's and Colitis Center ( Site 0132), Boston, Massachusetts
University of Michigan ( Site 0143), Ann Arbor, Michigan
Clinical Research Institute of Michigan, LLC ( Site 0108), Clinton Township, Michigan
Michigan Center of Medical Research (MICHMER) ( Site 3850), Farmington Hills, Michigan
Clinical Research Institute of Michigan, LLC ( Site 0150), Troy, Michigan
Huron Gastroenterology ( Site 3836), Ypsilanti, Michigan
Mayo Clinic in Rochester, Minnesota ( Site 0147), Rochester, Minnesota
BVL Research - Kansas ( Site 3847), Liberty, Missouri
Washington University School of Medicine ( Site 0129), Saint Louis, Missouri
Circuit Clinical /Middletown Medical PC ( Site 3831), Middletown, New York
NYU Langone Health - Inflammatory Bowel Disease Center (IBD) ( Site 3846), New York, New York
Lenox Hill Hospital ( Site 0128), New York, New York
New York Gastroenterology Associates ( Site 0159), New York, New York
University of North Carolina Medical Center ( Site 0140), Chapel Hill, North Carolina
Carolina Digestive Diseases and Endoscopy Center ( Site 3809), Greenville, North Carolina
Hospital of the University of Pennsylvania ( Site 0170), Philadelphia, Pennsylvania
University Gastroenterology ( Site 0164), Providence, Rhode Island
Gastroenterology Associates of Orangeburg ( Site 0149), Orangeburg, South Carolina
Vanderbilt Inflammatory Bowel Disease Clinic ( Site 0131), Nashville, Tennessee
Quality Medical Research ( Site 3807), Nashville, Tennessee
GI Alliance - Garland ( Site 0109), Garland, Texas
Baylor College of Medicine Medical Center ( Site 3812), Houston, Texas
The University of Texas Health Science Center at Houston-Internal Medicine-Division of Gastroentero ( Site 0144), Houston, Texas
Clinical Trial Network ( Site 3819), Houston, Texas
GI Alliance - Lubbock ( Site 0167), Lubbock, Texas
Caprock Gastro Research ( Site 0101), Lubbock, Texas
GI Alliance: Mansfield ( Site 0161), Mansfield, Texas
CARTA - Clinical Associates In Research Therapeutics Of America ( Site 0122), San Antonio, Texas
Southern Star Research Institute ( Site 0106), San Antonio, Texas
GI Alliance - San Marcos ( Site 0130), San Marcos, Texas
GI Alliance - Southlake ( Site 0104), Southlake, Texas
Tyler Research Institute ( Site 0105), Tyler, Texas
Texas Digestive Disease Consultants ( Site 0136), Webster, Texas
Velocity Clinical Research, Salt Lake City ( Site 3801), West Jordan, Utah
Richmond VA Medical Center ( Site 3845), Richmond, Virginia
Washington Gastroenterology - Bellevue ( Site 3844), Bellevue, Washington
Washington Gastroenterology - Tacoma ( Site 0102), Tacoma, Washington
MEDICAL COLLEGE OF WISCONSIN ( Site 0141), Milwaukee, Wisconsin
Centro de Investigaciones Médicas Mar del Plata ( Site 2101), Mar del Plata, Buenos Aires
CER medical Institute-Gastroenterology ( Site 2110), Quilmes, Caba
Hospital Provincial del Centenario ( Site 2108), Rosario, Santa Fe
C.I.C.E. 9 de Julio-CICE 9 DE JULIO ( Site 2103), San Miguel de Tucumán, Tucuman
Nepean Hospital-Gastroenterology/Hepatology ( Site 2501), Kingswood, New South Wales
Concord Repatriation General Hospital-Gastroenterology and Liver Services ( Site 2508), Sydney, New South Wales
Royal Brisbane and Women's Hospital ( Site 2500), Brisbane, Queensland
Mater Misericordiae Limited-Gastroenterology ( Site 2506), Brisbane, Queensland
Royal Adelaide Hospital-Gastroenterology/Hepatology ( Site 2504), Adelaide, South Australia
Monash Health-Gastroenterology ( Site 2505), Clayton, Victoria
The Alfred Hospital-Gastroenterology ( Site 2503), Melbourne, Victoria
St Vincent's Hospital ( Site 2510), Melbourne, Victoria
Universitaetsklinik fuer Innere Medizin I Innsbruck ( Site 0200), Innsbruck, Tirol
Medizinische Universität Wien-Klinik für Innere Medizin III - Abteilung für Gastroenterologie und H ( Site 0202), Vienna, Wien
Uniklinikum Salzburg-Innere Medizin I ( Site 0201), Salzburg, Not set
UZ Gent ( Site 0300), Gent, Oost-Vlaanderen
UZ Leuven-Gastroenterology - Inflammatory Bowel Disease ( Site 0301), Leuven, Vlaams-Brabant
MC Velingrad 2017 EOOD ( Site 0406), Velingrad, Pazardzhik
"Diagnostic - Consultative Center XX - Sofia" EOOD ( Site 0407), Sofia, Sofia (stolitsa)
DKC V - Plovdiv ( Site 0402), Plovdiv, Not set
MC Rusemed ( Site 0408), Ruse, Not set
MHAT Hadzhi Dimitar-Gastroenterology ( Site 0403), Sliven, Not set
Diagnostic Consultative Center 22 - Sofia ( Site 0401), Sofia, Not set
4th MHAT ( Site 0409), Sofia, Not set
Medica Plus Medical Center ( Site 0404), Veliko Tarnovo, Not set
Heritage Medical Research Clinic ( Site 0004), Calgary, Alberta
Gastroenterology and internal medicine research institute ( Site 0010), Edmonton, Alberta
SIX08 Gastroenterology ( Site 0013), Lethbridge, Alberta
Fraser Clinical Trials Inc. ( Site 0019), New Westminster, British Columbia
G.I.R.I. GI Research Institute Foundation ( Site 0001), Vancouver, British Columbia
Private Practice - Dr. Bruce Musgrave ( Site 0011), Kentville, Nova Scotia
Barrie GI Associates ( Site 0012), Barrie, Ontario
University Hospital - London Health Sciences Centre ( Site 0002), London, Ontario
Victoria Hospital & Children's Hospital - London Health Sciences Centre ( Site 0007), London, Ontario
West GTA Research Inc. ( Site 0017), Mississauga, Ontario
Toronto Immune & Digestive Health Institute ( Site 0005), Toronto, Ontario
Toronto Digestive Disease Associates ( Site 0006), Vaughan, Ontario
Centre Intégré de Santé et Service Sociaux de Chaudière-Appalaches ( Site 0015), Levis, Quebec
Centre Hospitalier de l Universite de Montreal - CHUM ( Site 0018), Montreal, Quebec
Montreal General Hospital ( Site 0003), Montreal, Quebec
ABP Research Services Corp. ( Site 0016), Ontario, Not set
Diex Recherche Quebec ( Site 0008), Quebec, Not set
Clinical Research Chile SpA ( Site 2201), Valdivia, Los Rios
Centro de Estudios Clínicos SAGA-CECSAGA ( Site 2203), Santiago., Region M. De Santiago
FALP-UIDO ( Site 2208), Santiago, Region M. De Santiago
Clínica Universidad de Los Andes ( Site 2202), Santiago, Region M. De Santiago
Clínica Alemana de Santiago ( Site 2209), Santiago, Region M. De Santiago
Clínica MEDS La Dehesa ( Site 2207), Santiago, Region M. De Santiago
CECIM ( Site 2200), Santiago, Region M. De Santiago
Pontificia Universidad Catolica de Chile-CICUC ( Site 2205), Santiago, Region M. De Santiago
The First Affiliated Hospital of Anhui Medical University ( Site 3957), Hefei, Anhui
Anhui Provincial Hospital ( Site 3947), Hefei, Anhui
Beijing Friendship Hospital Affiliate of Capital University ( Site 3923), Beijing, Beijing
Peking University Third Hospital ( Site 3909), Beijing, Beijing
Beijing Luhe Hospital Capital Medical University ( Site 3911), Beijing, Beijing
Chongqing University Three Gorges Hospital ( Site 3928), Chongqing, Chongqing
The First Affiliated Hospital Of Fujian Medical University ( Site 3904), Fuzhou, Fujian
The First Affiliated hospital of Xiamen University-Gastroenterology ( Site 3954), Xiamen, Fujian
Dongguan People's Hospital-Gastroenterology department ( Site 3944), Dongguan, Guangdong
Guangzhou Medical University 2nd Hospital ( Site 3908), Guangzhou, Guangdong
Southern Medical University Nanfang Hospital-Gastroenterology ( Site 3914), Guangzhou, Guangdong
The Sixth Affiliated Hospital of Sun Yat-sen University ( Site 3906), Guangzhou, Guangdong
Huizhou Municipal Central Hospital ( Site 3917), Huizhou, Guangdong
Yuebei People's Hospital Guangdong ( Site 3948), Shaoguan, Guangdong
The University of Hong Kong-Shenzhen Hospital ( Site 3955), Shenzhen, Guangdong
Shenzhen Hospital of Southern Medical University-Gastroenterology department ( Site 3905), Shenzhen, Guangdong
The Second Hospital of Hebei Medical University ( Site 3934), Shijiazhuang, Hebei
The Second Affiliated Hospital of Zhengzhou University ( Site 3935), Zhengzhou, Henan
Taihe Hospital ( Site 3941), Shiyan, Hubei
The Central Hospital of Wuhan ( Site 3939), Wuhan, Hubei
Renmin Hospital of Wuhan University ( Site 3912), Wuhan, Hubei
The Second Xiangya Hospital of Central South University ( Site 3930), Changsha, Hunan
Changzhou No.2 People's Hospital ( Site 3950), Changzhou, Jiangsu
Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School ( Site 3900), NanJing, Jiangsu
Zhongda Hospital Southeast University ( Site 3919), Nanjing, Jiangsu
Wuxi People's Hospital ( Site 3920), Wuxi, Jiangsu
The First Affiliated Hospital of Nanchang University ( Site 3926), Nanchang, Jiangxi
Tangdu Hospital of Fourth Military Medical University of Chinese People's Liberation Army ( Site 3929), Xian, Shaanxi
Binzhou Medical University Hospital ( Site 3953), Binzhou, Shandong
Taian City Central Hospital-gastroenterology department ( Site 3946), Taian, Shandong
Ruijin Hospital Shanghai Jiaotong University School of Medicine-Gastroneterology ( Site 3903), Shanghai, Shanghai
Shanghai East Hospital ( Site 3922), Shanghai, Shanghai
Renji Hospital Shanghai Jiao Tong University School of Medicine ( Site 3915), Shanghai, Shanghai
West China Hospital, Sichuan University ( Site 3951), Cheng Du, Sichuan
Tianjin Medical University General Hospital ( Site 3945), Tianjin, Tianjin
The First Teaching Hospital of Xinjiang Medical University. ( Site 3937), Urumqi, Xinjiang
First Affiliated Hospital of Kunming Medical University ( Site 3925), Kunming, Yunnan
Sir Run Run Shaw Hospital of Zhejiang University School of Medicine-GI Medicine ( Site 3916), Hangzhou, Zhejiang
Clínica las Américas ( Site 2318), Medellín, Antioquia
Clinica Medellin S.A ( Site 2317), Medellín, Antioquia
Clinica Somer-Unidad de Investigacion y Docencia ( Site 2303), Rionegro, Antioquia
Clinica de la Costa S.A.S. ( Site 2305), Barranquilla, Atlantico
Fundacion Santa Fe de Bogota ( Site 2316), Bogota, Cundinamarca
Oncologos del Occidente ( Site 2310), Pereira., Risaralda
Fundación Valle del Lili ( Site 2307), Cali, Valle Del Cauca
Klinička bolnica Merkur ( Site 0505), Zagreb, Grad Zagreb
Klinički bolnički centar Zagreb ( Site 0501), Zagreb, Grad Zagreb
Poliklinika Bates ( Site 0504), Zagreb, Grad Zagreb
Poliklinika Solmed ( Site 0502), Zagreb, Grad Zagreb
Poliklinika Borzan ( Site 0500), Osijek, Osjecko-baranjska Zupanija
Klinički Bolnički Centar Split ( Site 0503), Split, Splitsko-dalmatinska Zupanija
Vojenská Nemocnice Brno-Internal department ( Site 0605), Brno, Brno-mesto
Institut Klinicke a Experimentalni Mediciny-Klinika hepatogastroentrologie ( Site 0604), Praha, Praha 4
Nemocnice Slany ( Site 0601), Slany, Stredocesky Kraj
Hepato-Gastroenterologie HK ( Site 0602), Hradec Kralove, Not set
CEMDOE - Centro Médico de Diabetes, Obesidad y Especialidades ( Site 3601), Santo Domingo, Distrito Nacional
Tampereen yliopistollinen sairaala ( Site 4300), Tampere, Pirkanmaa
Pohjois-Karjalan keskussairaala ( Site 4302), Joensuu, Pohjois-Karjala
Turku University Hospital ( Site 4301), Turku, Varsinais-Suomi
Centre Hospitalier Universitaire de Nice - Hôpital l'Archet ( Site 0706), Nice, Alpes-Maritimes
CHU Bordeaux Haut-Leveque-Service d'Hépato-gastroentérologie ( Site 0700), Pessac, Aquitaine
Assistance Publique Hôpitaux de Marseille - Hôpital Nord ( Site 0714), Marseille, Bouches-du-Rhone
Centre Hospitalier Universitaire de Reims - Hôpital Robert Debré ( Site 0705), Reims, Champagne-Ardenne
CHU Besançon ( Site 0710), Besançon, Doubs
C.H.U. de Nimes. Hopital Caremeau ( Site 0718), Nimes, Gard
Hopital Beaujon ( Site 0716), Clichy, Hauts-de-Seine
CMC Ambroise Paré Hartmann - Institut des MICI ( Site 0709), Neuilly-sur-Seine, Hauts-de-Seine
CHU SAINT ELOI ( Site 0711), Montpellier, Languedoc-Roussillon
Centre Hospitalier Universitaire de Nantes - L' Hopital l'hôtel-Dieu ( Site 0701), Nantes, Loire-Atlantique
Centre Hospitalier Régional Universitaire de Nancy - Hôpitaux de Brabois ( Site 0708), Vandoeuvre lès Nancy, Meurthe-et-Moselle
centre hospitalier lyon sud ( Site 0707), Pierre-Bénite, Rhone
CHU d'Amiens-Picardie - Hôpital Sud-Hepato-gastroentérology ( Site 0712), Amiens, Somme
Hopital Henri Mondor ( Site 0717), Creteil, Val-de-Marne
Hôpitaux Universitaires Paris Sud - Hôpital Bicêtre ( Site 0715), Le Kremlin-Bicêtre, Val-de-Marne
Hôpital Saint Antoine ( Site 0703), Paris, Not set
Hôpital Saint-Louis ( Site 0702), Paris, Not set
LTD High Technology Hospital Medcenter ( Site 0802), Batumi, Ajaria
Caucasus Medical Centre ( Site 0801), Tbilisi, Ajaria
Caraps Medline ( Site 0803), Tbilisi, Not set
New Hospitals ( Site 0800), Tbilisi, Not set
Universitaetsklinikum Ulm. ( Site 0902), Ulm, Baden-Wurttemberg
Klinikum der Universität München Großhadern-Medizinische Klinik und Poliklinik II ( Site 0907), Munich, Bayern
Agaplesion Markus Krankenhaus ( Site 0904), Frankfurt am Main, Hessen
Medizinische Hochschule Hannover ( Site 0913), Hannover, Niedersachsen
Klinikum Lüneburg ( Site 0908), Lüneburg, Niedersachsen
Stadtische Kliniken Duisburg, Abtlg. Innere Medizin ( Site 0916), Duisburg, Nordrhein-Westfalen
Gastroenterologische Gemeinschaftspraxis Minden ( Site 0911), Minden, Nordrhein-Westfalen
Medizinisches Versorgungszentrum Portal 10 ( Site 0914), Münster, Nordrhein-Westfalen
St. Marien und St. Annastift Krankenhaus ( Site 0901), Ludwighafen Am Rhein, Rheinland-Pfalz
Universitätsklinikum Leipzig ( Site 0909), Leipzig, Sachsen
Universitaetsklinikum Schleswig-Holstein Campus Kiel ( Site 0903), Kiel, Schleswig-Holstein
Charité Campus Virchow-Klinikum ( Site 0906), Berlin, Not set
Städtisches Klinikum Brandenburg ( Site 0905), Brandenburg, Not set
Evangelismos General Hospital of Athens ( Site 4001), Athens, Attiki
THORACIC GENERAL HOSPITAL OF ATHENS "I SOTIRIA"-3rd Dept of Internal Medicine and Laboratory, Oncol ( Site 4000), Athens, Attiki
General Hospital of Nikaia-Piraeus "Agios Panteleimon" ( Site 4006), Nikaia Piraeus, Attiki
Ippokrateio General Hospital of Thessaloniki ( Site 4004), Thessaloniki, Kentriki Makedonia
University General Hospital of Heraklion-GASTROENTEROLOGY & HEPATOLOGY ( Site 4003), Heraklion, Kriti
Csőszi Endoszkópos KFT ( Site 1001), Kecskemét, Bacs-Kiskun
Mohácsi Kórház ( Site 1008), Mohács, Baranya
Békés Megyei Központi Kórház Dr. Réthy Pál Tagkórház-4. Belgyogyaszat Gasztroenterologia ( Site 1007), Békéscsaba, Bekescsaba
Heves Vármegyei Markhot Ferenc Oktatókórház és Rendelőintézet ( Site 1012), Eger, Heves
Gyöngyösi Bugát Pál Kórház ( Site 1011), Gyongyos, Heves
Komarom-Esztergom Varmegyei Szent Borbala Korhaz ( Site 1010), Tatabánya, Komarom-Esztergom
VeszLife Magánklinika ( Site 1002), Veszprém, Veszprem
Synexus Magyarorszag Kft. (Budapest DRS) ( Site 1009), Budapest, Not set
Semmelweis Egyetem ( Site 1006), Budapest, Not set
Pannónia Magánorvosi Centrum ( Site 1004), Budapest, Not set
Emek Medical Center ( Site 1106), Afula, Not set
Barzilai Medical Center ( Site 1109), Ashkelon, Not set
Rambam Health Care Campus ( Site 1101), Haifa, Not set
Bnai Zion Medical Center ( Site 1103), Haifa, Not set
Edith Wolfson Medical Center ( Site 1104), Holon, Not set
Shaare Zedek Medical Center ( Site 1108), Jerusalem, Not set
Meir Medical Center. ( Site 1102), Kfar Saba, Not set
Rabin Medical Center ( Site 1107), Petah Tikva, Not set
Sheba Medical Center ( Site 1100), Ramat Gan, Not set
Policlinico Universitario Monserrato-SC Gastroenterologia ( Site 1207), Monserrato, Cagliari
IRCCS Casa Sollievo della Sofferenza ( Site 1213), San Giovanni Rotondo, Foggia
Fondazione Policlinico Tor Vergata ( Site 1209), Rome, Lazio
Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico-Gastroenterology and Endoscopy Unit ( Site 1202), Milano, Lombardia
Istituto Clinico Humanitas-IBD center ( Site 1201), Rozzano, Lombardia
Ospedale Di Circolo-U.O.C. di Gastroenterologia ed Endoscopia Digestiva ( Site 1216), Rho, Milano
A.O.R.N. Ospedale dei Colli - Monaldi V. ( Site 1217), Napoles, Napoli
Azienda Ospedaliera San Camillo Forlanini ( Site 1204), Rome, Roma
Fatebenefratelli Isola Tiberina - Gemelli Isola ( Site 1214), Rome, Roma
Az. Osp. Ospedali Riuniti VILLA SOFIA-CERVELLO-U.O.S.D. Malattie Infiammatorie Croniche Intestinali ( Site 1210), Palermo, Sicilia
Azienda Ospedale - Università Padova-Surgery Oncology and Gastroenterology ( Site 1211), Padova, Veneto
Ospedale Sacro Cuore Don G. Calabria ( Site 1212), Negrar, Verona
IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola ( Site 1208), Bologna, Not set
ASST Fatebenefratelli Sacco-UOC Gastroenterologia ( Site 1200), Milano, Not set
Ospedale San Raffaele-Gastroenterology and Gastrointestinal Endoscopy ( Site 1205), Milano, Not set
Fondazione IRCCS Policlinico San Matteo-General Medicine ( Site 1206), Pavia, Not set
Aichi Medical University Hospital ( Site 2841), Nagakute, Aichi
Tokatsu Tsujinaka Hospital ( Site 2832), Abiko, Chiba
Tsujinaka Hospital - Kashiwanoha ( Site 2802), Kashiwa, Chiba
Toho University Sakura Medical Center ( Site 2805), Sakura, Chiba
Ehime Prefectural Central Hospital ( Site 2868), Matsuyama, Ehime
Kitakyushu Municipal Medical Center ( Site 2873), Kitakyushu, Fukuoka
Kurume University Hospital ( Site 2846), Kurume, Fukuoka
Gunma University Hospital ( Site 2850), Maebashi, Gunma
National Hospital Organization Fukuyama Medical Center ( Site 2831), Fukuyama, Hiroshima
Asahikawa City Hospital ( Site 2840), Asahikawa, Hokkaido
Asahikawa Medical University Hospital ( Site 2815), Asahikawa, Hokkaido
Sapporo Tokushukai Hospital ( Site 2808), Sapporo, Hokkaido
Sapporo Medical University Hospital ( Site 2829), Sapporo, Hokkaido
Medical Corporation Sapporo IBD Clinic ( Site 2842), Sapporo, Hokkaido
Sapporohigashi Tokushukai Hospital ( Site 2860), Sapporo, Hokkaido
Hyogo Medical University Hospital ( Site 2830), Nishinomiya, Hyogo
Hitachi General Hospital ( Site 2856), Hitachi, Ibaraki
Ishikawa Prefectural Central Hospital ( Site 2835), Kanazawa, Ishikawa
Kanazawa University Hospital ( Site 2839), Kanazawa, Ishikawa
Iwate Medical University Uchimaru Medical Center ( Site 2833), Morioka, Iwate
Gokeikai Ofuna Chuo Hospital ( Site 2801), Kamakura, Kanagawa
St. Marianna University Hospital ( Site 2852), Kawasaki, Kanagawa
Matsushima Hospital ( Site 2822), Yokohama, Kanagawa
Yokohama City University Medical Center ( Site 2865), Yokohama, Kanagawa
Mie University Hospital ( Site 2838), Tsu, Mie
Sai Gastroenterology/Proctology Clinic ( Site 2814), Fujiidera, Osaka
Kansai Medical University Hospital ( Site 2823), Hirakata, Osaka
Hamamatsu University Hospital ( Site 2874), Hamamatsu, Shizuoka
Matsuda Hospital ( Site 2826), Hamamatsu, Shizuoka
National Hospital Organization Shizuoka Medical Center ( Site 2837), Shimizu, Shizuoka
Institute of Science Tokyo Hospital ( Site 2827), Bunkyō, Tokyo
Ginza Central Clinic ( Site 2824), Chuo, Tokyo
Toranomon Hospital ( Site 2828), Minato-ku, Tokyo
Kitasato University Kitasato Institute Hospital ( Site 2817), Minato-ku, Tokyo
The Jikei University Hospital ( Site 2843), Minato, Tokyo
Kyorin University Hospital ( Site 2804), Mitaka-shi, Tokyo
NTT Medical Center Tokyo ( Site 2834), Shinagawa-ku, Tokyo
Yamanashi Prefectural Central Hospital ( Site 2836), Kofu, Yamanashi
Fukui Prefectural Hospital ( Site 2844), Fukui, Not set
Fukuoka University Hospital ( Site 2818), Fukuoka, Not set
Hiroshima University Hospital ( Site 2845), Hiroshima, Not set
Kagoshima University Hospital ( Site 2848), Kagoshima, Not set
Kagoshima IBD Gastroenterology Clinic ( Site 2821), Kagoshima, Not set
University Hospital,Kyoto Prefectural University of Medicine ( Site 2819), Kyoto, Not set
National Hospital Organization Kyoto Medical Center ( Site 2813), Kyoto, Not set
Ishida Clinic of IBD and Gastroenterology ( Site 2820), Oita, Not set
Okayama University Hospital ( Site 2870), Okayama, Not set
Infusion Clinic ( Site 2806), Osaka, Not set
National Hospital Organization Osaka National Hospital ( Site 2869), Osaka, Not set
Saga University Hospital ( Site 2812), Saga, Not set
Tokitokai Tokito Clinic Coloproctology Center ( Site 2811), Saitama, Not set
Tokyo Yamate Medical Center ( Site 2803), Tokyo, Not set
Toyama Prefectural Central Hospital ( Site 2807), Toyama, Not set
Yamagata University Hospital ( Site 2849), Yamagata, Not set
Wonju Severance Christian Hospital-Internal Medicine ( Site 3003), Wonju, Kang-won-do
The Catholic University Of Korea St. Vincent's Hospital-Gastroenterology ( Site 3006), Suwon-si, Kyonggi-do
Dong-A University Hospital ( Site 3010), Busan, Pusan-Kwangyokshi
Inje University Haeundae Paik Hospital ( Site 3009), Haeundae-gu, Pusan-Kwangyokshi
Chung-Ang University Hospital ( Site 3008), Dongjak-gu, Seoul
Yeungnam University Medical Center ( Site 3004), Daegu, Taegu-Kwangyokshi
The Catholic University of Korea, Daejeon St. Mary's Hospital ( Site 3011), Daejeon, Taejon-Kwangyokshi
Kyung Hee University Hospital ( Site 3013), Seoul, Not set
Seoul National University Hospital ( Site 3005), Seoul, Not set
Kangbuk Samsung Hospital-Internal Medicine ( Site 3002), Seoul, Not set
The Catholic University of Korea, Eunpyeong St. Mary's Hospital ( Site 3012), Seoul, Not set
Severance Hospital, Yonsei University Health System-Department of Internal Medicine ( Site 3000), Seoul, Not set
Asan Medical Center ( Site 3007), Seoul, Not set
Samsung Medical Center ( Site 3001), Seoul, Not set
SIA M & M Centrs ( Site 4502), Adazi, Adazu Novads
Liepaja Regional Hospital ( Site 4501), Liepaja, Not set
Hospital of Lithuanian University of Health Sciences Kauno klinikos ( Site 4600), Kaunas, Kauno Apskritis
VUL SANTAROS KLINIKOS ( Site 4601), Vilnius, Vilniaus Miestas
Hospital Tuanku Jaafar Seremban ( Site 4705), Seremban, Negeri Sembilan
Hospital Ampang ( Site 4703), Ampang, Selangor
Medica Sur-Clinica de Enfermedades Digestivas y Obesidad ( Site 2406), Mexico City, Distrito Federal
Morales Vargas Centro de Investigacion ( Site 2411), León, Guanajuato
PanAmerican Clinical Research - Guadalajara ( Site 2400), Guadalajara, Jalisco
Centro Medico Clinico Quirurgico Especializado en Investigación ( Site 2403), Tlajumulco De Zuniga, Jalisco
Hospital Universitario "Dr. Jose Eleuterio Gonzalez" ( Site 2409), Monterrey, Nuevo Leon
Centro Multidisciplinario para el Desarrollo Especializado de la Investigacion Clinica en Yucatan ( Site 2407), Merida, Yucatan
ICARO Investigaciones en Medicina ( Site 2405), Chihuahua, Not set
Centro de Investigación y Gastroenterología - S.C. ( Site 2410), Mexico City, Not set
Oaxaca Site Management Organization S.C. ( Site 2404), Oaxaca, Not set
Radboudumc ( Site 1402), Nijmegen, Gelderland
ETZ Elisabeth-Department of Gastroenterology and Hepatology ( Site 1403), Tilburg, Noord-Brabant
Ziekenhuis Bernhoven-Researchbureau ( Site 1401), Uden, Noord-Brabant
Onze Lieve Vrouwe Gasthuis ( Site 1405), Amsterdam, Noord-Holland
Amsterdam UMC, locatie VUmc-IBD Trial Unit ( Site 1400), Amsterdam, Noord-Holland
Deventer Ziekenhuis ( Site 1411), Deventer, Overijssel
Erasmus Medisch Centrum ( Site 1410), Rotterdam, Zuid-Holland
Franciscus Gasthuis & Vlietland, Locatie Gasthuis ( Site 1406), Rotterdam, Zuid-Holland
Universitair Medisch Centrum Utrecht ( Site 1404), Utrecht, Not set
Waikato Hospital ( Site 2903), Hamilton, Waikato
Hutt Valley District Health board HVDHB ( Site 2902), Lower Hutt, Wellington
Aotearoa Clinical Trials ( Site 2900), Auckland, Not set
Akershus Universitetssykehus ( Site 4200), Lørenskog, Akershus
Oslo Universitetssykehus Ullevål ( Site 4201), Oslo, Not set
Planetmed ( Site 1506), Wroclaw, Dolnoslaskie
Melita Medical ( Site 1519), Wroclaw, Dolnoslaskie
EMC Instytut Medyczny SA ( Site 1505), Wroclaw, Dolnoslaskie
Gastromed Sp. z o. o. ( Site 1513), Torun, Kujawsko-pomorskie
Med-Gastr Sp. z o.o., sp.k ( Site 1515), Lodz, Lodzkie
AmiCare Centrum Medyczne - Zgierska ( Site 1517), Lodz, Lodzkie
Allmedica ( Site 1508), Nowy Targ, Malopolskie
Vivamed Sp. z o.o. ( Site 1510), Warsawa, Mazowieckie
Centrum Zdrowia MDM ( Site 1512), Warszawa, Mazowieckie
WIP Warsaw IBD Point Profesor Kierkuś ( Site 1503), Warszawa, Mazowieckie
Twoja Przychodnia - Szczecinskie Centrum Medyczne ( Site 1502), Szczecin, Zachodniopomorskie
Sonomed Sp. z o. o. ( Site 1516), Szczecin, Zachodniopomorskie
Unidade Local de Saude Lisboa Ocidental - Hospital Egas Moniz ( Site 3306), Lisbon, Lisboa
Unidade Local de Saude de Braga - Hospital de Braga ( Site 3300), Braga, Not set
Hospital dos Lusíadas Lisboa ( Site 3303), Lisboa, Not set
Unidade Local de Saude de Santa Maria - Hospital de Santa Maria ( Site 3305), Lisboa, Not set
ULSAM - Hospital de Santa Luzia ( Site 3302), Viana do Castelo, Not set
Unidade Local de Saude Dão-Lafões - Hospital de São Teotónio ( Site 3308), Viseu, Not set
MEMORIAL HEALTHCARE INTERNATIONAL S.R.L ( Site 1606), Bucharest, Bucuresti
Fundeni Clinical Institute-Gastroenterology and Hepatology Center ( Site 1608), București, Bucuresti
Spitalul Clinic Judetean de Urgenta Cluj Napoca-Gastroenterology ( Site 1605), Cluj Napoca, Cluj
GastroMed ( Site 1609), Cluj-Napoca, Cluj
Spitalul Clinic Judetean Mures-Gastroenterology ( Site 1607), Targu Mures, Mures
S.C Centrul de Gastroenterologie Dr. Goldis S.R.L-Gastroenterology ( Site 1601), Timisoara, Timis
Asociatia Oncohelp ( Site 1610), Timisoara, Timis
S.C. Centrul Medical Medicum SRL-Gastroenterology ( Site 1604), Bucuresti, Not set
Clinical Hospital Center Dragisa Misovic ( Site 1708), Belgrade, Beograd
Clinical Hospital Center Zvezdara-Gastroenterology and hepatology Department ( Site 1705), Belgrade, Beograd
University Medical Center "Bezanijska kosa"-Gastroenterology and hepatology ( Site 1704), Belgrade, Beograd
Clinical Center Kragujevac ( Site 1703), Kragujevac, Beograd
General Hospital "Djordje Joanovic" ( Site 1707), Zrenjanin, Srednjebanatski Okrug
Breznianske centrum gastroenterologie ( Site 1806), Brezno, Banskobystricky Kraj
Fakultna nemocnica s poliklinikou F.D.Roosevelta Banska Bystrica ( Site 1802), Slovakia, Banskobystricky Kraj
Cliniq s.r.o. ( Site 1800), Bratislava, Bratislavsky Kraj
ENDOMED ( Site 1801), Kosice, Kosicky Kraj
KM Management ( Site 1804), Nitra, Nitriansky Kraj
Accout Center ( Site 1805), Sahy, Nitriansky Kraj
GASTRO I ( Site 1807), Presov, Presovsky Kraj
Gastro LM ( Site 1808), Presov, Presovsky Kraj
Wits Clinical Research-Research ( Site 3208), Johannesburg, Gauteng
Wits Clinical Research-Wits Clinical Research Bara ( Site 3206), Soweto, Gauteng
Panorama Medical Centre ( Site 3209), Cape Town, Western Cape
Spoke Research ( Site 3210), Cape Town, Western Cape
Life Kingsbury Hospital ( Site 3203), Cape Town, Western Cape
Private Practice - Dr. M.N. Rajabally ( Site 3213), Cape Town, Western Cape
Hospital Germans Trias i Pujol ( Site 3413), Badalona, Barcelona
Hospital Universitari Mutua Terrassa ( Site 3416), Terrassa, Barcelona
Hospital Galdakao-Usansolo ( Site 3409), Galdakao-Usansolo, Bizkaia
Hospital La Princesa-Gastroenterology ( Site 3411), Madrid, Madrid, Comunidad De
Fundación Jimenez Diaz ( Site 3420), Madrid, Madrid, Comunidad De
Hospital Universitario de Torrejon ( Site 3417), Torrejón de Ardoz, Madrid, Comunidad De
Hospital Universitario de Fuenlabrada-Digestive ( Site 3415), Fuenlabrada, Madrid
HOSPITAL CLINICO DE VALENCIA ( Site 3406), Valencia, Valenciana, Comunitat
Hospital Universitari i Politecnic La Fe-Enfermedad Inflamatoria Intestinal ( Site 3405), València, Valencia
HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑON-Aparato Digestivo ( Site 3403), Madrid, Not set
Hospital Universitario La Paz-Unidad de Enfermedad Inflamatoria Intestinal ( Site 3402), Madrid, Not set
Universitetssjukhuset i Linköping ( Site 4402), Linköping, Ostergotlands Lan
Danderyds Sjukhus ( Site 4401), Danderyd, Stockholms Lan
Karolinska Universitetssjukhuset Solna ( Site 4400), Stockholm, Stockholms Lan
Akademiska Sjukhuset ( Site 4403), Uppsala, Uppsala Lan
INTESTO-Gastroenterologische Praxis / Crohn-Colitis Zentrum Bern ( Site 1902), Bern, Berne
Cantonal Hospital St.Gallen-Klinik für Gastroenterologie / Hepatologie ( Site 1901), St.Gallen, Sankt Gallen
UniversitätsSpital Zürich-Gastroenterologie & Hepatologie ( Site 1900), Zürich, Zurich
Changhua Christian Hospital ( Site 3104), Changhua County, Changhua
National Taiwan University BioMedical Park Hospital ( Site 3103), Zhu Bei City, Hsinchu
China Medical University Hospital ( Site 3100), Taichung, Not set
National Taiwan University Hospital ( Site 3102), Taipei, Not set
Chang Gung Medical Foundation-Linkou Branch ( Site 3101), Taoyuan, Not set
Istanbul Universitesi Cerrahpasa-Internal Diseases ( Site 3503), Istanbul- Fatih, Istanbul
ANKARA UNIVERSITY IBNI SINA HOSPITAL ( Site 3507), Ankara, Not set
Hacettepe Universite Hastaneleri ( Site 3500), Ankara, Not set
Ankara Bilkent Şehir Hastanesi-Gastroenterology ( Site 3501), Ankara, Not set
Antalya Egitim ve Arastirma Hastanesi ( Site 3508), Antalya, Not set
Trakya University Medical Faculty Hospital ( Site 3510), Edirne, Not set
Eskisehir Osmangazi University Faculty of Medicine ( Site 3512), Eskisehir, Not set
Marmara Universitesi Pendik Egitim Arastirma Hastanesi ( Site 3505), Istanbul, Not set
Kocaeli University Medical Faculty Hospital ( Site 3509), Kocaeli, Not set
Communal non-profit enterprise "Regional clinical hospital of Ivano-Frankivsk Regional Council" ( Site 4115), Ivano-Frankivsk, Ivano-Frankivska Oblast
Center of Family Medicine Plus-Treatment Prevention Unit ( Site 4103), Kyiv, Kyivska Oblast
Communal Non-profit Enterprise of Lviv Regional Council "Lviv Regional Clinical Hospital"-proctology ( Site 4109), Lviv, Lvivska Oblast
Limited liability company "Medical center Health Clinic"-Gastroenterology, Hepatology and Endocrino ( Site 4107), Vinnytsia, Vinnytska Oblast
Communal Non-Commercial Enterprise "Vinnytsia City Clinical -Clinical Therapeutic Department #1 ( Site 4111), Vinnytsia, Vinnytska Oblast
Municipal Nonprofit Enterprise "Vinnytsia Regional Clinical -Gastroenterology department ( Site 4114), Vinnytsya, Vinnytska Oblast
Municipal Enterprise "Volyn Regional Clinical Hospital" of V-surgery department (abdominal, colopro ( Site 4113), Lutsk, Volynska Oblast
Medical Center "Universal Clinic "Oberig" of Limited Liability Company "Kapytal" ( Site 4100), Kyiv, Not set
Dobrobut Medical Center ( Site 4101), Kyiv, Not set
Medical Center of Private Enterprise "Sygma" ( Site 4108), Kyiv, Not set
Southmead Hospital ( Site 2004), Bristol, Bristol, City Of
Addenbrooke's Hospital ( Site 2005), Cambridge, Cambridgeshire
Royal Devon & Exeter Hospital-IBD Research Group ( Site 2001), Exeter, Devon
Doncaster Royal Infirmary ( Site 2006), Doncaster, England
Huddersfield Royal Infirmary ( Site 2010), Huddersfield, England
Whipps Cross University Hospital-Clinical Research Unit ( Site 2000), London, England
St. George's Hospital ( Site 2007), London, England
Southampton General Hospital-Gastroenterology ( Site 2003), Southampton, Hampshire
University College London Hospital-Clinical Research Facility ( Site 2002), London, London, City Of
Walsall Manor Hospital ( Site 2009), West Midlands, Walsall
Conditions: Ulcerative Colitis
CLIC-1901 for the Treatment of Patients With Relapsed/Refractory CD19 Positive Hematologic Malignancies
Recruiting
The investigators propose an early phase study defined as a phase I/II trial assessing safety, feasibility and efficacy of CLIC-1901 autologous anti-CD19 Chimeric Antigen Receptor T cells (CAR-T) cells for participants with relapsed/refractory CD19 positive (CD19+) Acute Lymphoblastic Leukemia (ALL) and non-Hodgkin's Lymphoma (NHL). The Initial Stage of the study (n=20 participants) will focus on feasibility and safety while the Extended Stage will include all participants enrolled in the study... Read More
The investigators propose an early phase study defined as a phase I/II trial assessing safety, feasibility and efficacy of CLIC-1901 autologous anti-CD19 Chimeric Antigen Receptor T cells (CAR-T) cells for participants with relapsed/refractory CD19 positive (CD19+) Acute Lymphoblastic Leukemia (ALL) and non-Hodgkin's Lymphoma (NHL). The Initial Stage of the study (n=20 participants) will focus on feasibility and safety while the Extended Stage will include all participants enrolled in the study (n=additional 80 participants for a total of 100) and will focus on efficacy and safety outcomes. In the proposed trial, we will administer our CAR-T cell product to these participants as a single infusion. Participants will undergo (a) lymphodepletion with cyclophosphamide and fludarabine, followed by (b) infusion of autologous CLIC-1901 CAR-T cells. All treatments will be delivered intravenously. Read Less
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
08/13/2025
Locations: Vancouver General Hospital, Vancouver, British Columbia +2 locations
Vancouver General Hospital, Vancouver, British Columbia
CancerCare Manitoba, Winnipeg, Manitoba
The Ottawa Hospital - General Campus, Ottawa, Ontario
Conditions: Acute Lymphoblastic Leukemia, Non-Hodgkin's Lymphoma, Chronic Lymphocytic Leukemia
An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia
Recruiting
Sodium zirconium cyclosilicate has been shown to be effective and safe in adults for the treatment of hyperkalaemia, and therefore it is expected to be beneficial in children. This study will evaluate the efficacy, safety and tolerability of sodium zirconium cyclosilicate for the treatment of hyperkalaemia in children \<18 years of age. Approximately 140 participants will enter CP at approximately 46 sites in locations including but not limited to Europe and North America for this study. Treatme... Read More
Sodium zirconium cyclosilicate has been shown to be effective and safe in adults for the treatment of hyperkalaemia, and therefore it is expected to be beneficial in children. This study will evaluate the efficacy, safety and tolerability of sodium zirconium cyclosilicate for the treatment of hyperkalaemia in children \<18 years of age. Approximately 140 participants will enter CP at approximately 46 sites in locations including but not limited to Europe and North America for this study. Treatment will include 3 phases: the CP, MP, and LTMP. Enrolment will start in 2 cohorts, ages 6 to \< 12 years and 12 to \< 18 years. After review of accumulated data, the independent Data Monitoring Committee (iDMC) will recommend whether to open enrolment in the ages 2 to \< 6 years cohort and later in the ages 0 to \< 2 years cohort. All eligible participants with hyperkalaemia will enter an open-label Correction Phase (CP) receiving a fixed dose of SZC three times daily (TID) for up to 3 days until normokalaemia is achieved. Within each age cohorts 2 to \< 18 years, initial participants will be allocated to the dose level (DL) based on body weight equivalent to an adult 5 g TID. After recommendation of higher DLs by the iDMC, subsequent participants may be allocated in the CP to on body weight equivalent to an adult 10 g TID and then potentially on body weight equivalent to an adult 15 g TID. All participants in the ages 0 to \< 2 years cohort will be assigned to the same DL which will be decided based on data from older age cohorts. Participants who successfully achieve normokalaemia in the CP will enter a 28-day open-label Maintenance Phase (MP), which will be initiated with once daily administration of the dose received TID in the CP. During MP, the Investigator is able to titrate the dose up or down in the range 2.5 g to 15 g body weight equivalent to maintain normokalaemia. For participants who, at the end of MP, are normokalaemic or hyperkalaemic without being on maximum dose, the MP is followed by the option to continue the study in a long term maintenance phase (LTMP) where the same titration regimen is used as in MP Read Less
Gender:
ALL
Ages:
Between 0 years and 18 years
Trial Updated:
08/13/2025
Locations: Research Site, Birmingham, Alabama +68 locations
Research Site, Birmingham, Alabama
Research Site, Atlanta, Georgia
Research Site, Baltimore, Maryland
Research Site, Grand Rapids, Michigan
Research Site, Saint Louis, Missouri
Research Site, Hackensack, New Jersey
Research Site, New York, New York
Research Site, Stony Brook, New York
Research Site, Charlotte, North Carolina
Research Site, Winston-Salem, North Carolina
Research Site, Akron, Ohio
Research Site, Cincinnati, Ohio
Research Site, Columbia, South Carolina
Research Site, Morgantown, West Virginia
Research Site, Campinas, Not set
Research Site, Sao Paulo, Not set
Research Site, São Paulo, Not set
Research Site, Calgary, Alberta
Research Site, Edmonton, Alberta
Research Site, Vancouver, British Columbia
Research Site, Montreal, Quebec
Research Site, Beijing, Not set
Research Site, Beijing, Not set
Research Site, Changsha, Not set
Research Site, Chengdu, Not set
Research Site, Chengdu, Not set
Research Site, Chongqing, Not set
Research Site, Hangzhou, Not set
Research Site, Hefei, Not set
Research Site, Shanghai, Not set
Research Site, Shanghai, Not set
Research Site, Berlin, Not set
Research Site, Essen, Not set
Research Site, Heidelberg, Not set
Research Site, Bhubaneshwar, Not set
Research Site, Gurgaon, Not set
Research Site, New Delhi, Not set
Research Site, Bunkyo-ku, Not set
Research Site, Fuchu-shi, Not set
Research Site, Fukuoka-shi, Not set
Research Site, Kawasaki-shi, Not set
Research Site, Kobe-shi, Not set
Research Site, Matsumoto-shi, Not set
Research Site, Nakagami-gun, Not set
Research Site, Saitama-Shi, Not set
Research Site, Sendai-Shi, Not set
Research Site, Shizuoka-Shi, Not set
Research Site, Białystok, Not set
Research Site, Krakow, Not set
Research Site, Warszawa, Not set
Research Site, Łódź, Not set
Research Site, Bucuresti, Not set
Research Site, București, Not set
Research Site, Cluj-Napoca, Not set
Research Site, Targu Mures, Not set
Research Site, Timisoara, Not set
Research Site, Samara, Not set
Research Site, Esplugues de Llobregat, Not set
Research Site, Madrid, Not set
Research Site, Dnipropetrovsk, Not set
Research Site, Kharkiv Region, Not set
Research Site, Kyiv, Not set
Research Site, Odesa, Not set
Research Site, Sumy, Not set
Research Site, Zaporizhzhia, Not set
Research Site, Glasgow, Not set
Research Site, Hampshire, Not set
Research Site, Manchester, Not set
Research Site, Nottingham, Not set
Conditions: Hyperkalaemia
QOL Improvement After Cardioversion of Persistent AF (QOL-CAFRCT)
Recruiting
Atrial fibrillation (AF) is a type of irregular heart rhythm due to electrical signal disturbances of the heart. It is a very common arrhythmia and the risk of developing AF increases with age and with other risk factors such as diabetes, high blood pressure, and underlying heart disease. The main complications of AF are heart failure and stroke. However, studies have shown that restoration of normal rhythm does not reduce these complications. Rather, these complications are mitigated by control... Read More
Atrial fibrillation (AF) is a type of irregular heart rhythm due to electrical signal disturbances of the heart. It is a very common arrhythmia and the risk of developing AF increases with age and with other risk factors such as diabetes, high blood pressure, and underlying heart disease. The main complications of AF are heart failure and stroke. However, studies have shown that restoration of normal rhythm does not reduce these complications. Rather, these complications are mitigated by controlling the heart rate and using blood thinners to prevent stroke. Symptoms secondary to AF can occur due to the irregular heart rate and poor contraction in the atria, the top chambers of the heart. These symptoms include shortness of breath, fatigue, reduced exercise tolerance, and palpitations. Restoring sinus rhythm can sometimes alleviate these symptoms. Given that studies to date have not shown a difference in hard clinical endpoints between rate and rhythm control strategies, the decision to proceed with rhythm control depends on the patient symptom burden.
Rhythm control strategies in patients with persistent AF include cardioversion back to sinus rhythm with long-term recurrence prevention via anti-arrhythmic drugs (AADs) or catheter ablation. However, many studies of these procedures omit a sham placebo control arm. No atrial fibrillation procedural intervention has been compared to a sham procedure. The cardioversion procedure can easily be compared to a "sham" alternative, as it is non-invasive with an expected response within days-to-weeks. Thus, a cardioversion versus "sham" cardioversion trial will allow us to truly assess the impact of a rhythm-control strategy on QOL. It is hypothesized that cardioversion of atrial fibrillation leads to significant improvement in quality of life (QOL) compared to sham cardioversion.
Understanding the true QOL impact of sinus rhythm restoration in patients with persistent AF is of significant importance in guiding strategies for the management of AF. Hence, by evaluating what the true effect of cardioversion on QOL in this blinded study, we can better understand the role of medical management and AF ablation in our patients and assess resource allocation to these procedures. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/13/2025
Locations: University of Ottawa Heart Institute, Ottawa, Ontario
University of Ottawa Heart Institute, Ottawa, Ontario
Conditions: Atrial Fibrillation
Outcomes From Remediation and Behavioural Intervention Techniques
Recruiting
It is currently unknown what factors predict response to Cognitive Behavioural Therapy for Psychosis (CBTp) or Cognitive Remediation Therapy (CR) among individuals with schizophrenia-spectrum disorders, thus the current trial will examine predictors of response to determine who requires the combined intervention and who might respond sufficiently to either monotherapy.
It is currently unknown what factors predict response to Cognitive Behavioural Therapy for Psychosis (CBTp) or Cognitive Remediation Therapy (CR) among individuals with schizophrenia-spectrum disorders, thus the current trial will examine predictors of response to determine who requires the combined intervention and who might respond sufficiently to either monotherapy. Read Less
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
08/13/2025
Locations: University of Toronto Scarborough, Scarborough, Ontario +1 locations
University of Toronto Scarborough, Scarborough, Ontario
Ontario Shores Centre for Mental Health Sciences (Ontario Shores), Whitby, Ontario
Conditions: Schizophrenia, Psychosis, Psychotic Disorders, Schizophrenia; Psychosis
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