All Clinical Trials in Canada

A listing of 3910 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

NCT06282575

Recruiting

The purpose of this study is to evaluate the efficacy and safety of Zanidatamab plus CisGem (Cisplatin and Gemcitabine) with or without the addition of a programmed death protein 1/ligand-1 (PD-1/L1) inhibitor (physician's choice of either Durvalumab or Pembrolizumab, where approved under local regulations) as first line of treatment for participants with human epidermal growth factor receptor 2 (HER2)-positive biliary tract cancer.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/29/2025

Locations: Rocky Mountain Cancer Centers, LLP, Lone Tree, Colorado +173 locations

Rocky Mountain Cancer Centers, LLP, Lone Tree, Colorado

AdventHealth Hematology and Oncology, Orlando, Florida

Winship Cancer Institute, Atlanta, Georgia

The University of Kansas Cancer Center - Westwood, Westwood, Kansas

Norton Cancer Institute - Audubon, Louisville, Kentucky

Ochsner Clinic Foundation, New Orleans, Louisiana

Tufts Medical Center, Boston, Massachusetts

University of Michigan Hospital, Ann Arbor, Michigan

Henry Ford Health System, Detroit, Michigan

Minnesota Oncology Hematology, P.A., Maple Grove, Minnesota

Atlantic Health System/Morristown Medical Center, Morristown, New Jersey

Laura and Isaac Perlmutter Cancer Center at NYU Langone - Ambulatory Care Center, New York, New York

Memorial Sloan Kettering Cancer Centers, New York, New York

Saint Francis Cancer Center, Greenville, South Carolina

SCRI Oncology Partners, Nashville, Tennessee

Texas Oncology - DFW, Dallas, Texas

University of Texas Southwestern Medical Center, Dallas, Texas

The Univerrsity of Texas MD Anderson Cancer Center, Houston, Texas

Virginia Commonwealth University, VCU Health, Richmond, Virginia

Hospital Italiano de Buenos Aires, Ciudad Autónoma de Buenos Aires (CABA), Buenos Altes

Fundación ARS Médica, San Salvador De Jujuy, Jujuy

Centro de Investigaciónes Clínicas - Clínica Viedma, Viedma, Río Negro

Hospital Provincial Del Centenario, Rosario, Santa Fe

Instituto Médico de la Fundación Estudios Clínicos, Rosario, Santa Fe

CAIPO Centro para la Atención Integral del Paciente Oncológico, San Miguel De Tucumán, Tucumán

Centro Médico en Oncología Clínica EXELSUS S.R.L, San Miguel De Tucumán, Tucumán

Centro Médico Privado CEMAIC, Córdoba, Not set

Imelda VZW, Bonheiden, Antwerpen

UZ Antwerpen, Edegem, Antwerpen

UZ Leuven, Leuven, Vlaams-Brabant

Liga Norte Riograndense Contra O Cancer, Natal, Rio Grande Do Norte

Irmandade Da Santa Casa de Misericordia de Porto Alegre - ISCMPA, Porto Alegrev, Rio Grande Do Sul

Hospital de Clinicas de Porto Alegre - HCPA, Porto Alegre, Rio Grande Do Sul

Fundação Pio XII Hospital de Amor de Barretos, Barretos, São Paulo

Fundação Doutor Amaral Carvalho - Hospital Amaral Carvalho, Jaú, São Paulo

Fundação Faculdade Regional de Medicina de São José do Rio Preto (FUNFARME), São José do Rio Preto, São Paulo

Hospital Nossa Senhora Da Conceição/Centro Integrado de Pesquisa em Oncologia CIPO-GHC, Porto Alegre, Not set

Instituto Nacional de Cancer - INCA, Rio de Janeiro, Not set

London Health Sciences Centre, LondonO, Ontario

Princess Margaret Cancer Centre - University Health Network, Toronto, Ontario

James Lind Centro de Investigacion del Cancer, Temuco, Araucanía

Servicios Médicos URUMED SpA, Rancagua, Libertador Gen Bernardo O Higgins

Clinica Puerto Montt, Puerto Montt, Los Lagos

Fundación Arturo López Pérez (FALP), Santiago, Metropolitana

Oncovida, Santiago, Metropolitana

Hospital Clinico Universidad de Chile, Santiago, Region Metropolitana

Centro de Investigacion y Especialidades Medicas (CDIEM), Santiago, Región-Metropolitana

Biocinetic Ltda, Santiago, Región-Metropolitana

Hunan Provincial People's Hospital, Changsha, Hunan

Jilin Cancer Hospital, Changchun, Jilin

Shandong Provincial Third Hospital, Jinan, Shandong

Sichuan Cancer Hospital, Chengdu, Sichuan

Fakultní nemocnice Brno, Interní hematologická a onkologická klinika, Brno, Not set

Fakultni nemocnice Hradec Kralove, Klinika onkologie a radioterapie, Hradec Kralove, Not set

Fakultni nemocnice v Motole, Onkologicka klinika, Praha 5, Not set

Docrates Cancer Center, Helsinki, Not set

Comprehensive Cancer Center, Helsinki University Hospital, Helsinki, Not set

Kuopio University Hospital, Kuopio, Not set

CHU de Toulouse- (Toulouse University Hospital Center), Toulouse, Cedex 9

CHU Besancon, Besançon, Cedex

CHU de Bordeaux - Hôpital Haut Leveque, Pessac, Cedex

CHU Brest Hôpital de la Cavale Blanche, Brest, Not set

CHU Estaing, Clermont-Ferrand, Not set

Hospital Beaujon University, Clichy, Not set

Hopital Henri Mondor, Créteil, Not set

CHU Montepellier - Hôpital Saint Eloi, Montpellier, Not set

CHU Poitiers, Poitiers, Not set

Institut de Cancérologie de l'Ouest, Saint-Herblain Cedex, Not set

Gustave Roussy, Villejuif Cedex, Not set

Universitätsklinikum Tübingen - Medizinische Universitätsklinik, Innere Medizin I, Tuebingen, Baden-Wuttemberg

Universitätsklinikum Freiburg - Klinik für Innere Medizin II,, Freiburg, Baden-Württemberg

Nationales Centrum für Tumorerkrankungen (NCT) Heidelberg, Heidelberg, Baden-Württemberg

LMU Universitätsklinikum München, Campus Großhadern, Medizinische Klinik und Poliklinik III - Hämatologie und Onkologie, München, Bayern

Krankenhaus Nordwest - Institut für Klinisch-Onkologische Forschung (IFK), Frankfurt, Hessen

Medizinische Hochschule Hannover - Klinik Fur Gastroenterologie, Hepatologie, Infektiologie und Endokrinologie, Hannover, Nieder-Sachsen

Technische Universität Dresden Medizinische Fakultät Carl Gustav Carus, Dresden, Sachsen

Universitätsklinikum Schleswig-Holstein - Campus Lübeck, Medizinische Klinik I (MKI), Lubeck, Schleswig-Holstein

Charité - Universitätsmedizin Berlin - Campus Virchow Klinikum, Medizinische Klinik mit Schwerpunkt Hamatologie und Tumorimmunologie, Berlin, Not set

Asklepios Tumorzentrum Hamburg, Asklepios Klinik Altona - Onkologie und Palliativmedizin mit Sektionen Hamatologie und Rheumatologie, Hamburg, Not set

KLES Dr Prabhakar Kore Hospital and Medical Research Centre, Belagavi, Karnataka

Tata Memorial Hospital, Mumbai, Maharashtra

Chopda Medicare & Research Centre Pvt. Ltd - Magnum Heart Institute, Nashik, Maharashtra

AIG Hospitals (A Unit of Asian Institute of Gastroenterology), Hyderabad, Telangana

Pi Health Cancer Hospital, Hyderabad, Telangana

Mahamana Pandit Madan Mohan Malviya Cancer Centre, Varanasi, Uttar Pradesh

Max Super Speciality Hospital - Saket (a unit of Devki Devi foundation), New Delhi, Not set

Rajiv Gandhi Cancer Institute And Research Centre, New Delhi, Not set

Rambam Health Care Campus, Haifa, Not set

The Hadassah University Medical Center, Ein Kerem Hospital, Jerusalem, Not set

Rabin Medical Center, Bellinson Hospital, Petah-Tikva, Not set

The Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, HaMerkaz, Not set

Tel Aviv Sourasky Medical Center (Ichilov), Tel Aviv, Not set

Azienda Ospedaliero Universitaria di Cagliari Presidio Ospedaliero Duilio Casula, Monserrato, Cagliari

Instituo di Candiolo, Fondazione del Piemonte per l'Oncologia (IRCCS), Candiolo, Torino

IRCCS Ospedale Policlinico San Martino, Genova, Not set

Fondazione IRCCS Istituto Nazionale per lo studio e la cura dei Tumori, Milano, Not set

AOU dell'Universit~ degli Studi della Campania Luigi Vanvitelli, Napoli, Not set

Veneto Institute of Oncology IOV - I.R.C.C.S., Padova, Not set

Azienda Ospedaliero - Universitaria Pisana, Pisa, Not set

Istituto Clinico Humanitas, Rozzano, Not set

Azienda Sanitaria Universitaria Friuli Centrale - P.O. S. Maria della Misericordia, Udine, Not set

Azienda Ospedaliera Universitaria Integrata Verona, Verona, Not set

Aichi Cancer Center, Nagoya-shi, Aichi

Chiba Cancer Center, Chiba-shi, Chiba

National Cancer Center Hospital East, Kashiwa, Chiba

National Hospital Organization Shikoku Cancer Center, Matsuyama-Shi, Ehime

National Hospital Organization Kyushu Cancer Center, Fukuoka-shi, Fukuoka

Hokkaido University Hospital, Sapporo-Shi, Hokkaidô

Kanazawa University Hospital, Kanazawa-shi, Isikawa

Kagoshima University Hospital, Kagoshima-shi, Kagoshima

Kanagawa Cancer Center, Yokohama-shi, Kanagawa

Kyoto University Hospital, Kyoto City, Kyôto

Mie University Hospital, Tsu-Shi, Mie

Tohoku University Hospital, Sendai-Shi, Miyagi

Niigata University Medical and Dental Hospital, Niigata-shi, Niigata

Osaka Prefectural Hospital Organization Osaka International Cancer Institute, Osaka-shi, Osaka

The University of Tokyo Hospital, Bunkyo-ku, Tokyo

National Cancer Center Hospital, Chuo-Ku, Tokyo

The Cancer Institute Hospital of Japanese Foundation For Cancer Research, Koto-Ku, Tokyo

Kyorin University Hospital, Mitaka-shi, Tokyo

Yamaguchi University Hospital, Ube-Shi, Yamaguchi

Osaka University Hospital, Suita-Shi, Ôsaka

CHA Bundang Medical Center, CHA University, Bundang-Gu, Seongnam-Si, Gyeonggi-do

National Cancer Center, Ilsandong-gu, Goyang-si, Gyeonggi-do

Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do

Pusan National University Hospital, Busan, Not set

Korea University Anam Hospital, Seoul, Not set

Seoul National University Hospital, Seoul, Not set

Severance Hospital, Yonsei University Health System, Seoul, Not set

Hanyang University Seoul Hospital, Seoul, Not set

Asan Medical Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Korea University Guro Hospital, Seoul, Not set

Unidade Local de Saude de Almada-Seixal, E.P.E. - Hospital Garcia de Orta, Almada, Not set

Unidade Local de Saude de Coimbra, EPE - Hospitais da Universidade de Coimbra, Coimbra, Not set

Unidade Local de Saúde de São José - Hospital de Santo António dos Capuchos, Lisboa, Not set

Champalimaud Clinical Center, Lisboa, Not set

Instituto Português de Oncologia Do Porto Francisco Gentil, EPE, Porto, Not set

Hospital Oncologico, Puerto Rico Medical Center, Rio Piedras, Not set

Spital Clinic Judetean de Urgenta Bihor, Oradea, Bihor

Centrul De Oncologie "SF. Nectarie" S.R.L., Craiova, Dolj

Institutul Clinic Fundeni, Bucharest, Not set

Centrul de Oncologie Euroclinic SRL, Iasi, Not set

University Clinical Center of Serbia, Clinic for Gastroenterohepatology, Belgrade, Not set

Military Medical Academy, Clinic for Gastroenterology and Hepatology, Belgrade, Not set

Oncology Institute of Vojvodina, Internal Oncology Clinic, Sremska Kamenica, Not set

Complejo Hospitalario Universitario de Santiago -Hospital Clinico Universitario de Santiago, Santiago de Compostela, A Coruna

Vall d'Hebron Institute of Oncology/Hospital Universitari de Vall d'Hebron, Barcelona, Not set

Hospital Universitario Reina Sofia, Cordoba, Not set

Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Hospital Universitario La Paz, Madrid, Not set

Hospital Regional Universitario de Malaga, Malaga, Not set

Clinica Universidad de Navarra, Pamplona, Not set

Hospital Universitario Virgen Macarena, Sevilla, Not set

Hospital Universitario y Politecnico La Fe, Valencia, Not set

Hospital Universitario Miguel Servet, Zaragoza, Not set

Onkologiska mottagningen, Sahlgrenska Universitetssjukhuset, Göteborg, Not set

Cancerstudieenheten Huddinge, Karolinska Universitetssjukhuset Huddinge, Huddinge, Not set

Onkologiska mottagningen, Skånes Universitetssjukhus Malmö, Malmö, Not set

Kaohsiung Medical University - Chung-Ho Memorial Hospital, Kaohsiung, Not set

Chang Gung Memorial Hospital Kaohsiung Branch of the Chang Gung Medical Foundation, Kaohsiung, Not set

National Cheng Kung University Hospital, Tainan, Not set

National Taiwan University Cancer Center, Taipei, Not set

Chang Gung Memorial Hospital Linkou Branch of the Chang Gung Medical Foundation, Taoyuan, Not set

Istanbul University Cerrahpasa Medical Faculty Hospital/Clinical Research Center, Istanbul, Fatih

Hacettepe University Cancer Institute, Ankara, Sihhiye

Akdeniz University Medical Faculty Hospital, Antalya, Not set

Trakya University Faculty of Medicine, Edirne, Not set

Mount Vernon Cancer Centre, London, England

NHS Foundation Trust Royal Marsden Hospital, London, England

The Christie NHS Foundation Trust, Manchester, England

Royal Marsden Hospital NHS Foundation Trust, Surrey, England

Western General Hospital, Edinburgh Cancer Centre, Edinburgh, Scotland

Conditions: Biliary Tract Cancer

Learn More ›

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

NCT06615479

Recruiting

The purpose of this study is to compare the efficacy and safety of arlo-cel (BMS-986393) versus standard regimens in adult participants with Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/29/2025

Locations: Local Institution - 0071, Birmingham, Alabama +125 locations

Local Institution - 0071, Birmingham, Alabama

UCLA Hematology/Oncology - Santa Monica, Los Angeles, California

Local Institution - 0130, Miami, Florida

Winship Cancer Institute, Emory University, Atlanta, Georgia

Local Institution - 0196, Boston, Massachusetts

Local Institution - 0067, Charlotte, North Carolina

Local Institution - 0216, Winston-Salem, North Carolina

Local Institution - 0193, Cleveland, Ohio

Fox Chase Cancer Center, Philadelphia, Pennsylvania

Local Institution - 0044, Salt Lake City, Utah

Local Institution - 0195, Milwaukee, Wisconsin

Hospital Italiano de Buenos Aires, ABB, Ciudad Autónoma De Buenos Aires

Local Institution - 0214, ABB, Ciudad Autónoma De Buenos Aires

Hospital Aleman, Buenos Aires, Ciudad Autónoma De Buenos Aires

Royal Prince Alfred Hospital, Camperdown, New South Wales

Local Institution - 0190, Liverpool, New South Wales

Local Institution - 0140, Brisbane, Queensland

Royal Adelaide Hospital, Adelaide, South Australia

Monash Health, Clayton, Victoria

Peter MacCallum Cancer Centre, Melbourne, Victoria

Local Institution - 0191, Melbourne, Victoria

Fiona Stanley Hospital, Murdoch, Western Australia

Ordensklinikum Linz GmbH Elisabethinen, Linz, Oberösterreich

Hanusch-Krankenhaus, Vienna, Not set

Local Institution - 0220, Edegem, Antwerpen

Local Institution - 0217, Brussels, Bruxelles-Capitale, Région De

Local Institution - 0162, Yvoir, Namur

UZ Gent, Gent, Oost-Vlaanderen

Local Institution - 0012, Nova Lima, Minas Gerais

Local Institution - 0103, São Paulo, SAO Paulo

Local Institution - 0013, Sao Paulo, São Paulo

Local Institution - 0031, São Paulo, Not set

Local Institution - 0069, Calgary, Alberta

Vancouver General Hospital, Vancouver, British Columbia

QEII Health Sciences Centre - Victoria General Site, Halifax, Nova Scotia

Local Institution - 0192, Hamilton, Ontario

CIUSSS de l'Est-de-l'Île-de-Montréal, Montreal, Quebec

Fakultní nemocnice Brno Bohunice, Brno, Brno-město

Local Institution - 0093, Hradec Kralove, Hradec Králové

Vseobecna fakultni nemocnice v Praze, Praha 2, Not set

Rigshospitalet, Copenhagen, Hovedstaden

Aarhus Universitetshospital, Skejby, Aarhus, Midtjylland

Local Institution - 0208, Roskilde, Sjælland

Odense Universitetshospital, Odense, Syddanmark

Helsinki University Hospital - Comprehensive Cancer Center (HYKS - Syöpäkeskus), Helsinki, Uusimaa

Hopital Claude Huriez - CHU de Lille, Lille, Nord

Local Institution - 0194, Nantes, Pays-de-la-Loire

Centre Hospitalier Lyon Sud, Pierre-Bénite, Rhône

Henri Mondor Hospital, Creteil, Val-de-Marne

Local Institution - 0210, Paris, Not set

TUM Universitätsklinikum, Technische Universität München, Munich, Bayern

Medizinische Hochschule Hannover, Hannover, Niedersachsen

Local Institution - 0211, Magdeburg, Sachsen-Anhalt

Local Institution - 0204, Chemnitz, Sachsen

Universitätsklinikum Leipzig, Leipzig, Sachsen

Local Institution - 0212, Kiel, Schleswig-Holstein

Local Institution - 0213, Berlin, Not set

Universitaetsklinikum Hamburg-Eppendorf, Hamburg, Not set

Universitaetsklinikum Heidelberg, Heidelberg, Not set

Klinikum Nuernberg Nord, Nuremberg, Not set

Universitaetsklinikum Wuerzburg, Wuerzburg, Not set

University Hospital of Patras, Patras, Achaḯa

Evangelismos General Hospital of Athens, Athens, Attikí

Local Institution - 0115, Chaidari, Attikí

Local Institution - 0125, Budapest, Not set

Local Institution - 0124, Debrecen, Not set

Sheba Medical Center, Ramat Gan, HaMerkaz

Sourasky Medical Center, Tel Aviv, Tell Abīb

Hadassah Medical Center, Jerusalem, Yerushalayim

Local Institution - 0107, Milan, Lombardia

Istituto Clinico Humanitas, Rozzano, Milano

Local Institution - 0128, Torino, Piemonte

Local Institution - 0108, Bologna, Not set

Local Institution - 0119, Genova, Not set

Local Institution - 0106, Udine, Not set

Nagoya City University Hospital, Nagoya, Aichi

Local Institution - 0105, Kashiwa, Chiba

Hyogo Medical University Hospital, Nishinomiya, Hyogo

Kanazawa University Hospital, Kanazawa, Ishikawa

Kyushu University Hospital, Fukuoka, Not set

Kumamoto University Hospital, Kumamoto, Not set

National Hospital Organization Okayama Medical Center, Okayama, Not set

Osaka Red Cross Hospital, Osaka, Not set

Japanese Red Cross Medical Center, Tokyo, Not set

Yamagata University Hospital, Yamagata, Not set

Local Institution - 0147, Seoul, Seoul-teukbyeolsi [Seoul]

Local Institution - 0146, Seoul, Seoul-teukbyeolsi [Seoul]

Local Institution - 0148, Seoul, Seoul-teukbyeolsi [Seoul]

Local Institution - 0149, Seoul, Seoul-teukbyeolsi [Seoul]

Local Institution - 0176, Nijmegen, Gelderland

Maastricht UMC+, Maastricht, Limburg

Local Institution - 0179, Amsterdam, Noord-Holland

Local Institution - 0161, Groningen, Not set

Local Institution - 0159, Utrecht, Not set

Universitair Medisch Centrum Utrecht, Utrecht, Not set

Oslo Universitetssykehus Ullevål, Oslo, Not set

Centrum Onkologii Ziemi Lubelskiej, Lublin, Lubelskie

Uniwersyteckie Centrum Kliniczne, Gdańsk, Pomorskie

Local Institution - 0084, Katowice, Not set

Local Institution - 0183, Łódź, Łódzkie

Instituto Português de Oncologia do Porto Francisco Gentil, EPE, Porto, Not set

Fundeni Clinical Institute, Bucuresti, București

Institutul Regional de Oncologie, Iași, Not set

Local Institution - 0178, Riyadh, Not set

Local Institution - 0180, Singapore, Central Singapore

Local Institution - 0181, Singapore, Central Singapore

CHUS - Hospital Clinico Universitario, Santiago de Compostela, A Coruña [La Coruña]

Local Institution - 0203, Palma, Balears [Baleares]

Local Institution - 0201, Badalona, Barcelona [Barcelona]

Clinica Universidad de Navarra, Pamplona, Navarra

Local Institution - 0202, Granada, Not set

Hospital Universitario de Salamanca - Complejo Asistencial Universitario de Salamanca, Salamanca, Not set

Local Institution - 0023, Lund, Skåne Län [se-12]

Karolinska Universitetssjukhuset Huddinge, Huddinge, Not set

Inselspital Bern, Bern, Berne

Cantonal Hospital St.Gallen, st.Gallen, Sankt Gallen

Local Institution - 0150, Taipei City, Taipei

Local Institution - 0151, Taichung, Not set

Local Institution - 0152, Taipei, Not set

Local Institution - 0200, Taipei, Not set

Local Institution - 0170, Ankara, Not set

Addenbrooke's Hospital, Cambridge, Cambridgeshire

Local Institution - 0155, London, London, City Of

Local Institution - 0157, Oxford, Oxfordshire

The Christie NHS Foundation Trust, Manchester, Not set

Local Institution - 0154, Newcastle upon Tyne, Not set

Conditions: Relapsed or Refractory Multiple Myeloma (RRMM)

Learn More ›

Intensive Cancer Screening After Cryptogenic Stroke

NCT05733416

Recruiting

The INCOGNITO Pilot Trial is a single centre pilot prospective randomized open-label blinded endpoint (PROBE) trial to assess the feasibility of a full-scale randomized trial to determine whether an occult cancer screening strategy of FDG PET/CT (F-fluorodeoxyglucose positron emission/computed tomography) in addition to usual care increases the number of occult cancers diagnosed after screening compared to usual care cancer screening alone in patients with cryptogenic stroke.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/29/2025

Locations: The Ottawa Hospital, Ottawa, Ontario

Conditions: Occult Cancer

Learn More ›

Hemoglobin Levels for Blood Transfusions During and After Surgery

NCT06718439

Recruiting

The goal of this pilot clinical trial is to learn if it is achievable to conduct a large-scale clinical trial whereby, the investigators will compare two ways of deciding when to give a blood transfusion during surgery. Participants in this study are adults undergoing surgery with a risk of significant blood loss. The main question it aims to answer is: * Is a trial designed to definitively test and compare two different red blood cell transfusion strategies feasible? Participants will: * Re... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/29/2025

Locations: The Ottawa Hospital, Ottawa, Ontario

Conditions: Blood Transfusion, Surgery

Learn More ›

Cold Versus Room Temperature Storage of Platelets for Bleeding in Hematologic Malignancy - a Pilot Trial

NCT05820126

Recruiting

This is a pilot trial to discover the feasibility of recruiting 50 pts over the course of 12 months. The trial is testing the efficacy of using cold-stored vs. room temperature stored (current standard of care) platelets to treat bleeding in persons with hematological disorders and thrombocytopenia.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/29/2025

Locations: The Ottawa Hospital - General Campus, Ottawa, Ontario

Conditions: Hematologic Malignancy

Learn More ›

A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)

NCT06455202

Recruiting

The purpose of this study is to establish the efficacy, safety and tolerability of barzolvolimab in adult participants with Chronic Spontaneous Urticaria (CSU) inadequately controlled by non-sedating second generation H1-antihistamines in comparison to placebo.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/29/2025

Locations: Allervie Clinical Research - Cullman, Cullman, Alabama +210 locations

Allervie Clinical Research - Cullman, Cullman, Alabama

Research Solutions of Arizona PC, Litchfield Park, Arizona

Medical Research of Arizona a division of Allergy, Asthma, & Immunology, Assoc. Ltd., Scottsdale, Arizona

Center for Dermatology & Plastic Surgery, Scottsdale, Arizona

Burke Pharmaceutical Research, Hot Springs, Arkansas

Kern Research, Inc., Bakersfield, California

UCLA Clinical Trials Contracts & Strategic Relations, Los Angeles, California

California Allergy and Asthma Medical Group, Los Angeles, California

LA Universal Research Center, Inc., Los Angeles, California

Allergy and Asthma Associates of Southern Cal, Mission Viejo, California

Apex Clinical Research, San Diego, California

WR-MCCR, San Diego, California

University Clinical Trials, San Diego, California

Clinical Science Institute, Santa Monica, California

Raffi Tachdjian MD, Inc, Santa Monica, California

Clarity Dermatology, PLLC, Castle Rock, Colorado

Asthma and Allergy Associates, Colorado Springs, Colorado

ClearlyDerm Boca Raton - ClinEdge - PPDS, Boca Raton, Florida

Driven Research LLC, Coral Gables, Florida

Dolphin Medical Research, Doral, Florida

Deluxe Health Center, Miami Lakes, Florida

South FL Clinical Research LLC, Miami, Florida

Dade Florida Clinical Research Center, Miami, Florida

Revival Clinical Research, Orlando, Florida

International Clinical Research - FL LLC, Sanford, Florida

Allergy and Asthma Diagnostic treatment Center - CRN - PPDS, Tallahassee, Florida

D&H Tamarac Research Center, LLC, Tamarac, Florida

Advanced Clinical Research Institute (ACRI) - Florida, Tampa, Florida

Deluxe Health Center, Tampa, Florida

MOORE Clinical Research, Inc. d/b/a TrueBlue Clinical Research, Tampa, Florida

University of South Florida, Tampa, Florida

Lane Dermatology Research - Centricity - PPDS, Columbus, Georgia

Skin Care Physicians of Georgia, Macon, Georgia

Treasure Valley Medical Research, Boise, Idaho

Sneeze Wheeze and Itch Associates LLC, Normal, Illinois

The Indiana Clinical Trials Center, PC, Plainfield, Indiana

South Bend Clinic, South Bend, Indiana

University of Kansas Medical Center, Kansas City, Kansas

Henry J. Kanarek - Allergy,Asthma&Immunology, Overland Park, Kansas

Velocity Clinical Research - The Dermatology Clinic - Baton Rouge - PPDS, Baton Rouge, Louisiana

Continental Clinical Research Solutions, LLC - ClinEdge - PPDS, Towson, Maryland

Brigham and Women's Hospital, Boston, Massachusetts

Derm Institute of Western Michigan, Caledonia, Michigan

Clarkston Skin Research - Clarkston, Clarkston, Michigan

Grekin Skin Institute, Warren, Michigan

Midwest Clinical Research, LLC, Saint Louis, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Skin Specialists PC, Omaha, Nebraska

Impact Medical / Circuit Clinical, Riverdale, New Jersey

OptiSkin Medical, New York, New York

Optimed Research Ltd - ClinEdge - PPDS, Columbus, Ohio

Clinical Partners LLC, Johnston, Rhode Island

University of Texas Health McGovern Medical, Bellaire, Texas

Western Sky Medical Research, El Paso, Texas

Austin Institute for Clinical Research, Inc., Pflugerville, Texas

Rainey & Finklea San Antonio Dermatology, San Antonio, Texas

Allergy Associates of Utah - Sandy, Murray, Utah

Jordan Valley Dermatology Center-South Jordan, South Jordan, Utah

Kalo Clinical Research, West Valley City, Utah

Virginia Dermatology and Skin Cancer Center - Norfolk, Norfolk, Virginia

Skin and Cancer Foundation - The Skin Hospital, Darlinghurst, New South Wales

St George Dermatology and Skin Cancer Center, Kogarah, New South Wales

Novatrials, Kotara, New South Wales

Momentum Clinical Research Darlinghurst, Sydney, New South Wales

Westmead Hospital, Westmead, New South Wales

Princess Alexandra Hospital, Brisbane, Queensland

Cornerstone Dermatology, Coorparoo, Queensland

Veracity Clinical Research Pty Ltd, Woolloongabba, Queensland

Box Hill Hospital, Box Hill, Victoria

Dr Rodney Sinclair Pty Ltd, East Melbourne, Victoria

The Alfred Hospital, Melbourne, Victoria

The Royal Melbourne Hospital, Parkville, Victoria

Medical Centre Asklepii OOD, Dupnitsa, Not set

Medical Center - Pulmo 2018, Haskovo, Not set

Medical Center Medconsult Pleven, Lovech, Not set

Multiprofile Hospital for Active Treatment - Pazardzhik AD, Pazardzhik, Not set

University Multiprofile Hospital for Active Treatment Sveti Georgi EAD, Plovdiv, Not set

Medical Center Prolet, Ruse, Not set

Medical Center Unimed EOOD, Sevlievo, Not set

Diagnostic-consultative center Ascendent EOOD, Sofia, Not set

Diagnostic and Consultative Center Aleksandrovska EOOD, Sofia, Not set

University Multiprofile Hospital for Active Treatment Aleksandrovska EAD, Sofia, Not set

University Multiprofile Hospital for Active Treatment "Tsaritsa Yoanna - ISUL", Sofia, Not set

Diagnostic-Consultative Centre Convex EOOD, Sofia, Not set

Laser Rejuvenation Clinics Edmonton D.T. Inc., Edmonton, Alberta

Vida Clinical Research, Edmonton, Alberta

Rejuvenation Dermatology Edmonton South, Edmonton, Alberta

LEADER research, Hamilton, Ontario

North Bay Dermatology Centre, North Bay, Ontario

Ottawa Allergy Research Corporation, Ottawa, Ontario

York Dermatology Clinic & Research Centre, Richmond Hill, Ontario

North York Research Inc., Toronto, Ontario

Joel Liem Medicine Professional Corporation, Windsor, Ontario

Saskatoon Dermatology Centre, Saskatoon, Saskatchewan

Centre de Recherche Saint-Louis (Québec), Québec, Not set

Clinica MEDS La Dehesa, Lo Barnechea, Not set

Hospital Base San Jose de Osorno, Osorno, Not set

Enroll SpA - Dr. Manuel Barros Borgono, Providencia, Not set

Clinica Davila - Recoleta, Recoleta, Not set

Centro Internacional de Estudios Clinicos (CIEC), Recoleta, Not set

BIOCINETIC Ltda, Santiago, Not set

Dermacross Clinica Dermatologica, Vitacura, Not set

Centro de Inmunología y Genética - CIGE S.A.S, Medellin, Not set

Hospital Alma Mater de Antioquia, Medellín, Not set

Fundación Centro de Investigation Clínica CIC, Medellín, Not set

Fundación Hospital Universidad del Norte, Soledad, Not set

Special Hospital Medico, Rijeka, Not set

Solmed Clinic, Zagreb, Not set

LTD" Healthy Future", Tbilisi, Not set

LTD "Center of Allergy and Immunology", Tbilisi, Not set

David Abuladze Georgian Italian Clinic, Tbilisi, Not set

LTD "Multiprofile Clinic Consilium Medulla", Tbilisi, Not set

Universitätsklinikum der RWTH Aachen Hautklinik, Aachen, Not set

Fachklinik Bad Bentheim, Bad Bentheim, Not set

Emovis GmbH, Berlin, Not set

Universitätsklinikum Bonn, Bonn, Not set

Klinische Forschung Dresden GmbH, Dresden, Not set

Universitätsklinikum Carl Gustav Carus an der TU Dresden, Dresden, Not set

Universitätsklinikum Düsseldorf, Düsseldorf, Not set

Universitätsklinikum Essen, Essen, Not set

Eurofins bioskin Research Center Dermalology, Hamburg, Not set

UKSH Lübeck, Institut für Entzündungsmedizin, Lübeck, Not set

Universitätsklinikum Mannheim, Mannheim, Not set

Universitätsklinikum Münster, Münster, Not set

Hautarztpraxis Dariusch Mortazawi, Remscheid, Not set

Universitäts-Hautklinik, Studienzentrum Immundermatologie, Tübingen, Not set

Debreceni Egyetem Klinikai Kozpont Nagyerdei Campus, Debrecen, Not set

Szent-Gyorgyi Albert Klinikai Kozpont, Szeged, Not set

Allergo-Derm Bakos Kft., Szolnok, Not set

Nirmal Hospital PVT LTD, Surat, Gujarat

Medical College Baroda & SSG Hospital, Vadodara, Gujarat

Shree Hospital & Critical Care Centre, Nagpur, Maharashtra

Assured Care Plus Hospital, Nashik, Maharashtra

Oyster & Pearl Hospitals, Pune, Maharashtra

Excelcare Hospital, Jaipur, Rajasthan

G.S.V.M. Medical College - Kanpur, Kanpur, Uttar Pradesh

B. J. Medical College and Civil Hospital, Ahmedabad, Not set

KLES Dr Prabhakar Kore Hospital & Medical Research Centre, Belgaum, Not set

All India Institute of Medical Sciences, Bhubaneswar, Not set

K R Hospital, Mysore, Not set

Deenanath Mangeshkar Hospital and Research Centre, Pune, Not set

Sumandeep Vidyapeeth University - Dhiraj Hospital, Vadodara, Not set

IRCCS Ospedale Policlinico San Martino, Genova, Not set

Asst Fbf Sacco, Milano, Not set

Azienda Ospedale Università di Padova, Padova, Not set

Humanitas Research Hospital, Rozzano, Not set

AOU San Giovanni di Dio e Ruggi d'Aragona, Salerno, Not set

IRCCS Policlinico San Donato, San Donato Milanese, Not set

Ospedale San Lazzaro PO Molinette, Torino, Not set

CD8 Klinika, Kaunas, Not set

UAB Ausros Medicinos Centras, Kaunas, Not set

UAB "Alerginių susirgimų diagnostikos ir gydymo centras", Vilnius, Not set

Santaros KTC (klinikiniu tyrimu centras), Vilnius, Not set

CECYPE, Morelia, Not set

Unidad de Medicina Especializada, San Juan Del Río, Not set

AmdsterdamUMC locatie AMC, Amsterdam, Not set

Bravis Hospital, Roosendaal, Not set

University Medical Center Utrecht, Utrecht, Not set

Klinika Dermatologii i Dermatologii Onkologicznej, Częstochowa, Not set

Centrum Medyczne Pratia Częstochowa, Częstochowa, Not set

Centrum Kliniczno-Badawcze J.Brzezicki,B.Górnikiewicz-Brzezicka, Lekarze Spółka Partnerska, Elbląg, Not set

Synexus Polska Sp. z o.o., Gdańsk, Not set

Mazowieckie Centrum Badań Klinicznych SC IWONA CZAJKOWSKA ANNA PODRAZKA-SZCZEAPANIAK, Grodzisk Mazowiecki, Not set

Centrum Medyczne "All-Med" Badania Kliniczne, Kraków, Not set

Centrum Medyczne Plejady, Kraków, Not set

Velocity Nova Sp. z o.o., Lublin, Not set

Pro Life Medica ETG Lublin, Lublin, Not set

LUXDERM Specjalistyczny Gabinet Dermatologiczny Prof. dr hab. n. med. Dorota Krasowska, Lublin, Not set

Medicome Sp. Z O.O., Oświęcim, Not set

Centrum Alergologii Teresa Hofman Sp. z.o.o., Poznań, Not set

EMC Instytut Medyczny SA, PL Certus Szpital i Ambulatorium, Poznań, Not set

Specjalistyczny Niepubliczny Zaklad Opieki Zdrowotnej Alergologia Plus Osrodek Diagnostyki I Terapii Uczulen, Poznań, Not set

Uniwersytecki Szpital Kliniczny im. Fryderka Chopina w Rzeszowie Klinika Dermatologii i Dermatologii Onkologicznej, Rzeszów, Not set

EMED Centrum Usług Medycznych Ewa Śmiałek, Rzeszów, Not set

ALERGO-MED SPECJALISTYCZNA PRZYCHODNIA LEKARSKA Spolka. z o. o., Tarnów, Not set

Medicover Integrated Clinical Services Sp. z o.o. Centrum Medyczne Warszawa, Warszawa, Not set

Synexus Polska Sp. z o.o., Warszawa, Not set

ETG Warszawa, Warszawa, Not set

MAXDERM s.r.o., Bardejov, Not set

Cliniq s.r.o., Bratislava, Not set

Derma therapy spol. s.r.o., Bratislava, Not set

ALERSA, sro, Košice, Not set

Fakultna nemocnica Trnava, Trnava, Not set

Hospital del Mar, Barcelona, Not set

Hospital Universitari Puerta del Mar, Cadiz, Not set

Hospital Universitario de La Princesa, Madrid, Not set

Clinica Universidad Navarra- Madrid, Madrid, Not set

Hospital 12 De Octubre, Madrid, Not set

Hospital Universitario Fundación Alcorcón, Madrid, Not set

Clinica Universidad Navarra- Pamplona, Pamplona, Not set

Complejo Hospitalario Universitario de Pontevedra- Centro Especialidades de Mollabao, Pontevedra, Not set

Hospital Quironsalud Madrid, Pozuelo De Alarcón, Not set

Hospital universitario Virgen Macarena, Sevilla, Not set

FutureMeds Sevilla, Sevilla, Not set

Hospital Universitario de Torrejón, Torrejón De Ardoz, Not set

Hospital Universitari i Politecnic La Fe de Valencia, Valencia, Not set

Hospital de Manises, Valencia, Not set

Siriraj Hospital, Bangkok Noi, Not set

Maharaj Nakorn Chiang Mai Hospital, Chiang Mai, Not set

Thammasat University Hospital, Khlong Luang, Not set

Khon Kaen University, Khon Kaen, Not set

Hôpital Hédi Chaker, Sfax, Not set

La Rabta Hospital, Tunis, Not set

Habib Thameur Hospital, Tunis, Not set

Cambridge University Hospitals, Addenbrooke's Hospital, Cambridge, Not set

Queen Elizabeth University Hospital, Glasgow, Not set

St James's University Hospital, Leeds, Not set

The Royal London Hospital, London, Not set

Velocity Clinical Research, North London - PPDS, North Finchley, Not set

Virtual Clinical Trials Centre, The Stables, Oxford, Not set

University Hospitals Plymouth NHS Trust, Plymouth, Not set

Conditions: Chronic Spontaneous Urticaria

Learn More ›

Evolut™ EXPAND TAVR II Pivotal Trial

NCT05149755

Recruiting

Obtain safety and effectiveness data to support indication expansion for the Medtronic TAVR System to include patients with moderate, AS.

Gender:

ALL

Ages:

65 years and above

Trial Updated:

07/29/2025

Locations: University of Alabama at Birmingham (UAB) Hospital, Birmingham, Alabama +98 locations

University of Alabama at Birmingham (UAB) Hospital, Birmingham, Alabama

Abrazo Arizone Heart Hospital, Phoenix, Arizona

HonorHealth Scottsdale Shea Medical Center, Scottsdale, Arizona

Los Robles Hospital & Medical Center, Thousand Oaks, California

University of Colorado Hospital, Aurora, Colorado

Saint Vincents Medical Center, Bridgeport, Connecticut

Hartford Hospital, Hartford, Connecticut

MedStar Washington Hospital Center, Washington, District of Columbia

Morton Plant Hospital, Clearwater, Florida

University of Florida, Gainesville, Florida

Saint Vincent's Medical Center Riverside, Jacksonville, Florida

Orlando Health, Orlando, Florida

Tallahassee Memorial Hospital, Tallahassee, Florida

Tampa General Hospital, Tampa, Florida

Jewish Hospital, Louisville, Kentucky

Terrebonne General Medical Center, Houma, Louisiana

The Johns Hopkins Hospital, Baltimore, Maryland

Tufts Medical Center, Boston, Massachusetts

Beth Israel Deaconess Medical Center, Boston, Massachusetts

Baystate Medical Center, Springfield, Massachusetts

University of Michigan Health System - University Hospital, Ann Arbor, Michigan

Ascension Saint John Hospital, Detroit, Michigan

Spectrum Health, Grand Rapids, Michigan

Abbott Northwestern Hospital, Minneapolis, Minnesota

Mayo Clinic, Rochester, Minnesota

SSM Health Saint Louis University Hospital, Saint Louis, Missouri

Catholic Medical Center, Manchester, New Hampshire

Deborah Heart and Lung Center, Browns Mills, New Jersey

Englewood Hospital & Medical Center, Englewood, New Jersey

Northwell Health, Manhasset, New York

The Mount Sinai Hospital, New York, New York

Mission Hospital, Asheville, North Carolina

Wake Forest University Heatlh Sciences, Winston-Salem, North Carolina

University Hospitals Cleveland Medical Center, Cleveland, Ohio

Cleveland Clinic, Cleveland, Ohio

The Ohio State University Wexner Medical Center, Columbus, Ohio

Kettering Health Main Campus, Kettering, Ohio

Integris Baptist Medical Center, Oklahoma City, Oklahoma

Oregon Health & Science University Hospital, Portland, Oregon

Lehigh Valley Hospital, Inc, Allentown, Pennsylvania

UPMC Pinnacle Harrisburg Campus, Harrisburg, Pennsylvania

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

Monument Health Rapid City Hospital, Rapid City, South Dakota

Erlanger Medical Center, Chattanooga, Tennessee

Medical City Dallas, Dallas, Texas

Texas Health Harris Methodist Hospital Fort Worth, Fort Worth, Texas

Houston Methodist Hospital, Houston, Texas

Methodist Hospital San Antonio, San Antonio, Texas

Intermountain Cardiovascular and Thoracic Surgery, Salt Lake City, Utah

The University of Vermont, Burlington, Vermont

Carilion Roanoke Memorial Hospital, Roanoke, Virginia

Providence Sacred Heart Medical Center & Children's Hospital, Spokane, Washington

West Virginia University, Morgantown, West Virginia

Aurora Saint Lukes Medical Center, Milwaukee, Wisconsin

The Alfred Hospital, Melbourne, Victoria

Fiona Stanley Hospital, Murdoch, Not set

University Hospital Sankt Poelten, Sankt Pölten, Not set

Allgemeines Krankenhaus - Universitätskliniken Wien, Wien, Not set

CHU de Liege- Hopital du Sart Tilman, Liège, Not set

Sunnybrook Health Sciences Centre, Toronto, Ontario

Montreal Heart Hospital, Montréal, Quebec

Institut Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ), Quebec City, Quebec

Queen Elizabeth II Health Sciences Centre, Halifax, Not set

CHU de Rennes - Hôpital Pontchaillou, Rennes, Brittany

CHRU Brest - Hôpital de la Cavale Blanche, Brest, Not set

Centre Hospitalier Universitaire de Clermont-Ferrand - Gabriel-Montpied, Clermont-Ferrand, Not set

Hôpital de la Timone, Marseille, Not set

Institut Mutualiste Montsouris, Paris, Not set

Hôpital Européen Georges Pompidou, Paris, Not set

Clinique Pasteur, Toulouse Cedex, Not set

Universitäts-Herzzentrum Freiburg - Bad Krozingen, Bad Krozingen, Not set

Universitätsklinikum Bonn, Bonn, Not set

Kath Saint Johannes-Gesellschaft Dortmund gGmbH Saint Johannes-Hospital Dortmund, Dortmund, Not set

Herzzentrum Leipzig GmbH, Leipzig, Not set

Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz, Not set

Klinikum der Universität München - Campus Grosshadern, München, Not set

Galway University Hospitals - University Hospital Galway (UHG), Galway, Not set

Shaare Zedek Medical Center, Jerusalem, Not set

Rabin Medical Center- Beilinson Hospital, Petah Tikva, Not set

Presidio Ospedaliero Gaspare Rodolico, Catania, Not set

Ospedale San Raffaele - Milano, Milano, Not set

IRCCS Policlinico San Donato, San Donato Milanese, Not set

Shonan Kamakura General Hospital, Kanagawa, Kamakura

Tokai University Hospital, Isehara, Kanagawa

Kawasaki Saiwai Hospital, Kawasaki, Kanagawa

Osaka Keisatsu Hospital, Osaka, Not set

Osaka University Hospital, Osaka, Not set

Catharina Ziekenhuis, Eindhoven, Not set

Universitair Medisch Centrum Groningen, Groningen, Not set

St Antonius Ziekenhuis, Nieuwegein, Not set

Erasmus MC, Rotterdam, Not set

Hospital Universitari Clínic de Barcelona, Barcelona, Not set

Hospital Universitario Ramón y Cajal, Madrid, Not set

Complejo Asistencial Universitario de Salamanca, Salamanca, Not set

Hospital Clínico Universitario de Valladolid, Valladolid, Not set

Skanes Universitetssjukhus, Lund, Not set

Inselspital - Universitätsspital Bern, Bern, Not set

Royal Victoria Hospital - Belfast Health and Social Care Trust, Belfast, U.k.

Saint Bartholomew's Hospital, London, Not set

Conditions: Moderate Aortic Valve Stenosis

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A Long-Term Study of Elafibranor in Adult Participants With Primary Biliary Cholangitis

NCT06016842

Recruiting

The participants of this study will have confirmed Primary Biliary Cholangitis (PBC) and cirrhosis (scarring of the liver). PBC is a slowly progressive disease, characterised by damage to the bile ducts in the liver, leading to a build-up of bile acids which causes further damage. The liver damage in PBC may lead to cirrhosis. PBC may also be associated with multiple symptoms. Many patients with PBC may require liver transplant or may die if the disease progresses and a liver transplant is not... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/29/2025

Locations: Arizona Liver Health, Tucson, Arizona +147 locations

Arizona Liver Health, Tucson, Arizona

Arkansas Diagnostic Center, PA, Little Rock, Arkansas

Southern California Research Center, Coronado, California

Cedars-Sinai Medical Center, Los Angeles, California

GastroIntestinal BioSciences, Los Angeles, California

University of California Los Angeles, Los Angeles, California

University of California Davis Medical Center, Sacramento, California

University of Colorado, Aurora, Colorado

Peak Gastroenterology Associates, Colorado Springs, Colorado

South Denver Gastroenterology, P.C., Englewood, Colorado

Rocky Mountain Gastroenterology, Littleton, Colorado

University Of Miami School Of Medicine, Center For Liver Diseases, Miami, Florida

International Center for Research, Tampa, Florida

University of Kansas Medical Center (KUMC) - University of Kansas Liver Center - Hepatology Clinic, Kansas City, Kansas

Louisiana Research Center, LLC, Shreveport, Louisiana

University of Michigan Health System, Ann Arbor, Michigan

Huron Gastroenterology Associates - Center for Digestive Care, Ypsilanti, Michigan

Southwest Gastroenterology Associates, PC (SWGA), Albuquerque, New Mexico

NYU Langone Gastroenterology and Hepatology Associates, New York, New York

University of Pittsburgh, Pittsburgh, Pennsylvania

Medical University of South Carolina, Charleston, South Carolina

Gastroenterology Center of the Midsouth, Cordova, Tennessee

Texas Clinical Research Institute, Arlington, Texas

American Research Corporation, Austin, Texas

Rush University Medical Center - University Cardiovascular Surgeons, Dallas, Texas

Liver Center of Texas, Dallas, Texas

Methodist Transplant Physicians, Dallas, Texas

University of Texas Southwestern Medical Center at Dallas, Dallas, Texas

Baylor Scott & White All Saints Medical Center - Forth Worth, Fort Worth, Texas

Liver Associates of Texas, Houston, Texas

Houston Methodist Cancer Center, Houston, Texas

Gastro health & Nutrition, Katy, Texas

American Research Corporation at The Texas Liver Institute, San Antonio, Texas

Impact Research Tx, Waco, Texas

University of Virginia Medical Center, Charlottesville, Virginia

Bon Secours St. Mary's Hospital of Richmond, Inc, Richmond, Virginia

Virginia Commonwealth University Medical Center - West Hospital, Richmond, Virginia

Medstar Georgetown Transplant Institute University Hospital (MGUH), Columbia, Washington

Velocity Clinical Research at Liver Institute Northwest, Seattle, Washington

DIM Centro Medico, Buenos Aires, Not set

Fundacion Respirar (Centro Medico Dra. De Salvo) - Instituto Argentino de Investigaciones Clinicas (IAIC) S.R.L, Buenos Aires, Not set

Hospital Britanico de Buenos Aires, Buenos Aires, Not set

Hospital Italiano de Buenos Aires, Buenos Aires, Not set

Centro Medico Colon, Córdoba, Not set

Hospital El Cruce, Florencio Varela, Not set

Hospital Espanol de Mendoza, Mendoza, Not set

Hospital Universitario Austral, Pilar, Not set

Sunshine Coast University Hospital, Birtinya, Not set

Footscray Hospital, Western Health, Footscray, Not set

Nepean Clinical School, Kingswood, Not set

Monash University - Monash Health -Monash Medical Centre, Melbourne, Not set

St George Hospital, Sydney, Not set

Westmead Hospital, Westmead, Not set

Universitair Ziekenhuis Antwerpen, Edegem, Not set

Ziekenhuis Oost-Limburg, Genk, Not set

Gent University Hospital, Gent, Not set

Algemeen Ziekenhuis Delta, Roeselare, Not set

Hospital de Clinicas de Porto Alegre (HCPA), Porto Alegre, Not set

Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Not set

Hospital de Base - Centro Integrado de Pesquisa ( CIP ), São Paulo, Not set

Universidade Estadual Paulista Julio De Mesquita Filho (UNESP) Hospital das Clinicas Faculdade de Medicina de Botucatu (HCFMB), São Paulo, Not set

Diagnostic-Consultative Center Aleksandrovska EOOD, Sofia, Not set

Tokuda Hospital, Dept. of Internal Medicine, Sofia, Not set

University Hospital City Clinic Cancer Center, Sofia, Not set

University of Alberta - Faculty of Medicine & Dentistry - The Centre of Excellence for Gastrointestinal Inflammation and Immunity Research (CEGIIR), Edmonton, Not set

University Health Network (UHN) - Toronto General Hospital (TGH) - Toronto General Research Institute (TGRI), Toronto, Not set

Universidad De Los Andes, Las Condes, Not set

Enroll SpA, Santiago, Not set

University of Chile Clinical Hospital (Hospital Clinico de la Universidad de Chile), Santiago, Not set

Centro Medico Cedid - Centro de Diagnostico Digestivo, Viña Del Mar, Not set

Hepato-Gastroenterologie HK, s.r.o., Hradec Králové, Not set

Krajska Nemocnice Liberec, Liberec, Not set

Artroscan, Ostrava, Not set

Research Site s.r.o., Plzen, Not set

Institute for Clinical and Experimental Medicine - IKEM, Prague, Not set

Bispebjerg Hospital, Copenhagen, Not set

Centre Hospitalier Regional Universitaire de Lille - Hopital Claude Huriez, Lille, Not set

Hospices Civils de Lyon (HCL) - Hopital de la Croix-Rousse, Lyon, Not set

Hopital Saint Joseph - Marseille, Marseille, Not set

CHU de Nice, Hopital de l'Archet, Nice, Not set

Assistance Publique - Hopitaux de Paris (AP-HP) - Hopital Universitaire Pitie Salpetriere (Hopital Pitie-Salpetriere), Paris, Not set

CHU Poitiers, Poitiers, Not set

Clinique Pasteur, Toulouse, Not set

Hopital Paul-Brousse - APHP, Villejuif, Not set

General Hospital of Athens Laiko, Athens, Not set

General Oncological Hospital of Kifisia Oi Agioi Anargyroi, Athens, Not set

Agios Savvas Regional Cancer Hospital, Athen, Not set

GeneIppokratio General Hospital of Thessaloniki, Thessaloníki, Not set

Central Hospital of Northern Pest - Military Hospital, Budapest, Not set

Kenezy County Hospital, Debrecen, Not set

Szegedi Tudomanyegyetem AOK, I. sz Belgyogyaszati Klinika, Szeged, Not set

Azienda Ospedaliero Universitaria Modena, Modena, Not set

Ospedale San Gerardo, Monza, Not set

Azienda Ospedaliero Universitaria Federico II di Napoli, Naples, Not set

Azienda Ospedaliera di Padova - U.O.C. di Gastroenterologia, Padova, Not set

Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone, Palermo, Not set

Fondazione I.R.C.C.S. Policlinico San Matteo, Pavia, Not set

Azienda Ospedaliero Universitaria Pisana, Pisa, Not set

Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo, Not set

Pusan National University Hospital (PNUH), Busan, Not set

Keimyung University Dongsan Hospital, Daegu, Not set

The Catholic University of Korea Daejeon St.Mary's Hospital, Daejeon, Not set

Inje University Ilsan Paik Hospital, Goyang-si, Not set

Korea University Ansan Hospital, Gyeonggi-do, Not set

Inha University Hospital, Incheon, Not set

Kyungpook National University Hospital (KNUH), Junggu, Not set

CHA Bundang Medical Center, CHA University, Seongnam-si, Not set

Chung-Ang University Hospital, Seoul, Not set

Hallym University Kangnam Sacred Heart Hospital, Seoul, Not set

Korea University Guro Hospital, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Seoul National University Bundang Hospital (SNUBH), Seoul, Not set

Seoul National University Hospital, Seoul, Not set

Severance Hospital, Yonsei University Health System, Seoul, Not set

The Catholic University of Korea, Eunpyeong St. Mary's Hospital, Seoul, Not set

The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, Not set

The Catholic University of Korea, Uijeongbu St. Mary's Hospital, Uijeongbu, Not set

Centro de Investigacion y Gastroenterologia SC, Ciudad de mexico, Not set

Centro de Investigacion Medico Biologica y Terapia Avanzada, Jalisco, Not set

Medical Care & Research, Yucatán, Not set

Canterbury District Health Board, Christchurch, Not set

Waikato Hospital, Hamilton, Not set

NZOZ Twoje Zdrowie EL Sp. z o.o., Elbląg, Not set

Uniwersyteckie Centrum Kliniczne im. Prof. K. Gibinskiego Slaskiego Uniwersytetu Medycznego, Katowice, Not set

Krakowskie Centrum Medyczne Sp.z.o.o - FutureMeds, Kraków, Not set

Szpital Uniwersytecki w Krakowie, Kraków, Not set

Krakowskie Centrum Medyczne Sp.z.o.o. - FutureMeds, Małogoskie, Not set

Niepubliczny Zaklad Opieki Zdrowotnej (NZOZ) - Poliklinika Doktora Bessera, Sosnowiec, Not set

FutureMeds Warszawa Centrum, Warszawa, Not set

FutureMeds sp. z o. o, Wrocław, Not set

Centrul Pentru Studiul Metabolismului, Bucharest, Not set

Sana S.R.L, Bucharest, Not set

Spital Clinic Dr I Cantacuzino, Bucharest, Not set

Cluj County Clinical Emergency Hospital, Cluj-Napoca, Not set

Gastromedica Srl, Iaşi, Not set

Hospital Clinic i Provincial de Barcelona, Barcelona, Not set

Hospital Universitario Vall d'Hebron, Barcelona, Not set

Clinica Universidad Navarra-Sede Madrid, Madrid, Not set

Hospital General Universitario Gregorio Maranon (HGUGM), Madrid, Not set

Hospital Universitario La Paz, Madrid, Not set

Hospital Universitario Puerta de Hierro de Majadahonda, Majadahonda, Not set

Hospital Universitario Virgen de la Victoria, Málaga, Not set

Hospital De Montecelo, Pontevedra, Not set

Institut d Investigacio i Innovacio Parc Tauli, Hospital Universitari Parc Tauli, Sabadell, Not set

Hospital Universitario Virgen del Rocio, Sevilla, Not set

Hospital Universitario y Politecnico La Fe, Valencia, Not set

Hospital Universitario Rio Hortega, Valladolid, Not set

Hospital Universitario Miguel Servet, Zaragoza, Not set

Conditions: Primary Biliary Cholangitis (PBC)

Learn More ›

A Study to Evaluate the Efficacy and Safety of JCAR017 in Adult Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin Lymphoma (NHL)

NCT04245839

Recruiting

This is a global Phase 2, open-label, single-arm, multicohort, multicenter study to evaluate efficacy and safety of JCAR017 in adult subjects with r/r FL or MZL. The study will be conducted in compliance with the International Council on Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use/Good Clinical Practice (GCP) and applicable regulatory requirements. This study is divided into three periods: * Pretreatment, which consists of screening assessme... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/29/2025

Locations: UCLA Medical Centre-Santa Monica, Santa Monica, California +58 locations

UCLA Medical Centre-Santa Monica, Santa Monica, California

University Of Colorado Cancer Center, Aurora, Colorado

Yale Cancer Center, New Haven, Connecticut

Local Institution - 0601, Hollywood, Florida

Washington University School Of Medicine, Miami, Florida

Northwestern University, Chicago, Illinois

Local Institution - 109, Niles, Illinois

University Of Iowa, Iowa City, Iowa

Cancer Center of Kansas, Wichita, Kansas

University of Maryland - Greenebaum Comprehensive Cancer Center, Baltimore, Maryland

Massachusetts General Hospital - Dana-Farber Cancer Institute, Boston, Massachusetts

Beth Israel Deaconess Medical Center, Boston, Massachusetts

Karmanos Cancer Center, Detroit, Michigan

Local Institution - 118, Detroit, Michigan

Atlantic Health System Morristown Medical Center, Morristown, New Jersey

Memorial Sloan Kettering Cancer Center, New York, New York

Novant Health Presbyterian Medical Center, Charlotte, North Carolina

Local Institution - 120, Fargo, North Dakota

Cleveland Clinic Foundation, Cleveland, Ohio

Providence Cancer Center/Earle A. Chiles Res. Inst., Portland, Oregon

University of Pennsylvania - Perelman Center for Advanced Medicine, Philadelphia, Pennsylvania

Local Institution - 126, Pittsburgh, Pennsylvania

Local Institution - 113, Sioux Falls, South Dakota

Local Institution - 125, Knoxville, Tennessee

Texas Oncology, Dallas, Texas

Houston Methodist Hospital, Houston, Texas

The University of Texas - MD Anderson Cancer Center, Houston, Texas

University Of Virginia Health System, Charlottesville, Virginia

Fred Hutchinson Cancer Center, Seattle, Washington

Allgemeinen Krankenhaus (AKH) Wien - Medizinische Universitaet Wien, Wien, Not set

Princess Margaret Cancer Centre, Toronto, Ontario

Hopital Maisonneuve - Rosemont, Montreal, Quebec

CHRU-Hopital Claude Huriez, Lille, Not set

CHU Montpellier - Hôpital Saint Eloi, Montpellier CEDEX 5, Not set

Hopital Saint Louis, Paris Cedex 10, Not set

Centre Hospitalier Lyon-Sud, Pierre-Benite CEDEX, Not set

Centre Hospitalier Universitaire de Rennes - Hopital Pontchaillou, Rennes Cedex 02, Not set

Institut Universitaire du Cancer Toulouse - Oncopole - CHU de TOULOUSE, Toulouse, Not set

Universitaetsklinikum Ulm, Ulm, Baden-Wurttemberg

Local Institution - 504, Regensburg, Bayern

Local Institution - 506, Berlin, Not set

Local Institution - 503, Karlsruhe, Not set

Local Institution - 505, Kiel, Not set

University Hospital Cologne, Köln, Not set

LMU Klinikum der Universitat Munchen, Munich, Not set

Azienda Ospedaliera Papa Giovanni Xxiii, Bergamo, Not set

Local Institution - 302, Bologna, Not set

Istituto Nazionale Per Lo Studio E La Cura Dei Tumori Fondazione Giovanni Pascale, Naples, Not set

Local Institution - 553, Sapporo-shi, Hokkaido

Local Institution - 550, Chuo-ku, Tokyo

Local Institution - 551, Minato-ku, Tokyo

Local Institution - 552, Fukuoka, Not set

Local Institution - 352, Barcelona, Not set

Hospital General Universitario Gregorio Marañon, Madrid, Not set

Hospital Universitario de Salamanca - Complejo Asistencial Universitario de Salamanca, Salamanca, Not set

Hospital Virgen Del Rocio, Sevilla, Not set

Karolinska Hospital, Stockholm, Not set

University College London Hospitals NHS Foundation Trust - University College Hospital, London, Not set

The Christie NHS Foundation Trust, Manchester, Not set

Conditions: Lymphoma, Non-Hodgkin

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Imaging of Vitreous Opacities in a Canadian Population

NCT06204848

Recruiting

The goal of this clinical trial is to capture imaging data of eye floaters in the population to build an imaging database to learn more about them in. Participants will imaged with an investigational ophthalmic imaging device to capture images of their floaters.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/28/2025

Locations: Alberta Retina Consultants, Edmonton, Alberta

Conditions: Floaters, Vitreous Opacities

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A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis

NCT06588855

Recruiting

This Phase III, multicenter, double-blind, placebo-controlled study will evaluate the efficacy and safety of induction therapy with Afimkibart (RO7790121) compared with placebo in participants with moderately to severely active ulcerative colitis (UC).

Gender:

ALL

Ages:

Between 16 years and 80 years

Trial Updated:

07/28/2025

Locations: Mayo Clinic Hospital, Scottsdale, Arizona +144 locations

Mayo Clinic Hospital, Scottsdale, Arizona

Om Research LLC, Apple Valley, California

Valley View Internal Medicine, Garden Grove, California

Gastro Care Associates, Lancaster, California

Hi Tech and Global Research, LLC, Coral Gables, Florida

The Sister Life Research, Hialeah, Florida

LCC Medical Research Institute, LLC, Miami, Florida

Ambert Medical Research, Miami, Florida

Gastroenterology Institute of Orlando, Orlando, Florida

Digestive and Liver Center of Florida, Orlando, Florida

University of South Florida School of Medicine Morsani Center for Advanced Health Care, Tampa, Florida

Guardian Angel Research Center, LLC, Tampa, Florida

Santos Research Center, CORP, Tampa, Florida

Atlanta Gastroenterology Associates, Atlanta, Georgia

Illinois Gastroenterology Group-Glenview powered by GI Alliance, Glenview, Illinois

GI Alliance - Gurnee, Gurnee, Illinois

Kansas Gastroenterology, LLC under Clinical Trials Network, Wichita, Kansas

Delta Gastroenterology & Endoscopy Center, Southaven, Mississippi

Ellipsis Research Group, Brooklyn, New York

DiGiovanna Inst for Med Ed&Res, North Massapequa, New York

Queens Village Medical Care, Queens Village, New York

Gastroenterology Group of Rochester under CTNx, Rochester, New York

Charlotte Gastroenterology and Hepatology, P.L.L.C, Charlotte, North Carolina

Omega Research North Carolina, LLC, Fuquay-Varina, North Carolina

Dayton Gastroenterology, Inc., Beavercreek, Ohio

University of Cincinnati Hospital, Cincinnati, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Ohio State University, Hilliard, Ohio

Frontier Clinical Re search, LLC, Uniontown, Pennsylvania

Gastroenterology Associates, PA PA of Greenville, Greenville, South Carolina

Amel Med LLC, Georgetown, Texas

Cano Medical Center, Harlingen, Texas

Texas Digestive Specialists, Harlingen, Texas

Baylor Scott and White Medical Center, Temple, Texas

Emeritas Research Group, Lansdowne Town Center, Virginia

Hospital Britanico, Ciudad Autonoma Bs As, Not set

Instituto Medico CER, Quilmes, Not set

Macquarie University Hospital, Macquarie Park, New South Wales

Coral Sea Clinical Research Institute, Mackay, Queensland

Footscray Hospital, Footscray, Victoria

Royal Melbourne Hospital, Parkville, Victoria

Ordensklinikum Linz Barmherzige Schwestern, Linz, Not set

Klinikum Wels-Grieskirchen, Wels, Not set

AZORG Campus Aalst-Moorselbaan, Aalst, Not set

CHU St Pierre (St Pierre), Brussels, Not set

Cliniques Universitaires St-Luc, Bruxelles, Not set

Hospital Moinhos de Vento, Porto Alegre, Rio Grande Do Sul

CECIP - Centro de Estudos Clínicos do Interior Paulista, Jaú, São Paulo

MC " Sveti Ivan Rilski Chudotvorets- 2010, Plovdiv, Not set

"City Clinic UMHAC" EOOD, Sofia, Not set

Barrie GI Associates, Barrie, Ontario

London Health Sciences Centre Uni Campus, London, Ontario

TIDHI Innovation Inc., Toronto, Ontario

CIUSSS-de-l?Est-de-l?Île-de-Montréal, Montreal, Quebec

Centro de Investigación Clínica UC-CICUC, Santiago, Not set

Beijing No.6 Hospital, Beijing, Beijing

The First Affilliated Hospital of Kunming Medical University, Kunming, Yunnan

Third Xiangya Hospital Centrel South University, Changsha, Not set

West China Hospital of Sichuan University, Chengdu City, Not set

The second Affiliated Hospital of Guangzhou Medical University, Guangzhou City, Not set

Guangzhou First People's Hospital, Guangzhou, Not set

Sir Run Run Shaw Hospital Zhejiang University, Hangzhou City, Not set

Huizhou Central People's Hospital, Huizhou, Not set

The Second Affiliated Hospital of Nanchang University, Nanchang City, Not set

The First Affiliate Hospital of Guangxi Medical University, Nanning, Not set

The First Affiliated Hospital of Ningbo University, Ningbo City, Not set

The Affiliated Hospital of Medical College Qingdao University, Qingdao, Not set

Ruijin Hospital Shanghai Jiaotong University School of Medicine, Shanghai City, Not set

Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, Not set

Shengjing Hospital of China Medical University, ShenYang, Not set

First Affiliated Hospital of Soochow University, Suzhou, Not set

The First Affiliated Hospital of Xiamen University, Xiamen, Not set

Zhongshan Hospital Xiamen University, Xiamen, Not set

Borzan Polyclinic, Osijek, Not set

Hepato-Gastroenterologie HK, s.r.o., Hradec Kralove, Not set

Fakultni nemocnice Ostrava, Ostrava - Poruba, Not set

ISCARE a.s., Praha 7, Not set

Ålborg Universitets Hospital, Ålborg, Not set

CHU Tours - Hôpital Trousseau, Chambray les Tours, Not set

CHU Clermont Ferrand - Hôtel Dieu, Clermont-Ferrand, Not set

Hôpital Henri Mondor, Créteil, Not set

Polyclinique Grand Sud, Nimes, Not set

Hôpital de Brabois Adultes, Vandoeuvre-les-nancy, Not set

Universitätsklinikum Heidelberg, Heidelberg, Not set

Medizinisches Zentrum Klinikum Lueneburg, Lueneburg, Not set

Észak-Pesti Centrumkórház-Honvédkórház, Budapest, Not set

Semmelweis Egyetem, Budapest, Not set

Vasutegeszsegugyi Kft. - Debreceni Egeszsegugyi Kozpont, Debrecen, Not set

Vas-Oxy Egeszsegugyi Kft, Szombathely, Not set

Fejer Varmegyei Szent György Egyetemi Oktatokorhaz, Székesfehérvár, Not set

Gujarat Gastro and Vascular Hospital, Surat CITY, Gujarat

SR Kalla Memorial Gastro & General Hospital, Jaipur, Rajasthan

Soroka Medical Center, Be'er Sheva, Not set

Azienda Ospedaliero Universitaria Di Bologna - Policlinico S Orsola Malpighi-Via Massarenti, Bologna, Emilia-Romagna

Policlinico Universitario Campus Biomedico Di Roma, Roma, Lazio

Ospedale Isola Tiberina Gemelli, Roma, Lazio

Asst Degli Spedali Civili Di Brescia, Brescia, Lombardia

IRCCS Ospedale San Raffaele, Milano, Lombardia

Azienda Ospedaliera San Gerardo di Monza, Monza MI, Lombardia

Istituto Clinico Humanitas, Rozzano (MI), Lombardia

IRCCS Ospedale Sacro Cuore Don Calabria, Negrar, Veneto

Boca Clinical Trials Mexico S.C. (Cd. Mexico), Miguel Hidalgo, Mexico CITY (federal District)

FAICIC S de R.L. de C.V, Veracruz, Not set

ETZ Elisabeth, Tilburg, Not set

Szpital Zakonu Bonifratrow Sw. Jana Bozego w Lodzi sp. z o.o., ?ód?, Not set

Gastromed Kralisz, Romatowski, Stachurska sp.j., Bia?ystok, Not set

Medical Center Kermed, Bydgoszcz, Not set

Szpital Miejski sw. Jana Paw?a II w Elblagu, Elblag, Not set

Centrum Medyczne CLW-med Aneta Cichomska , Joanna Luka -Wendrowska, Grudzadz, Not set

Osrodek Badan Klinicznych Bd Research, I?awa, Not set

MZ Badania Slowik Zymla Sp.j., Knurów, Not set

Centrum Medyczne Promed, Kraków, Not set

Medrise sp z o.o, Lublin, Not set

EMC Instytut Medyczny SA, Pozna?, Not set

Gabinety Lekarskie Rivermed, Pozna?, Not set

Clinical Research Center Sp. z o.o. MEDIC-R Spó?ka Komandytowa, Pozna?, Not set

Endoskopia Sp. z o.o., Sopot, Not set

Sonomed Sp. z o.o., Szczecin, Not set

Centrum Zdrowia-MDM, Warszawa, Not set

Medon Clinical Research sp. z o.o, Warszawa, Not set

Vivamed Spolka Z Ograniczona Odpowiedzialnoscia, Warszawa, Not set

PlanetMed sp. z o.o., Wroc?aw, Not set

Centrum Medyczne Oporow, Wroclaw, Not set

Hospital de Braga, Braga, Not set

Hospital da Luz Lisboa, Lisboa, Not set

Centro Hospitalar do Algarve - Hospital de Portimao, Portimao, Not set

Hospital de Sao Joao, Porto, Not set

Centro Hospitalar de Entre Douro e Vouga - H. São Sebastião, Santa Maria Da Feira, Not set

Hospital Sao Teotonio, Viseu, Not set

Klinical Investigations Group LLC, San Juan, Not set

General Hospital "Djordje Joanovic", Zrenjanin, Not set

Accout Center s.r.o., Šahy, Not set

Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Madrid

Hospital Clinico Univ. Lozano Blesa, Zaragoza, Not set

Hospital Universitario Miguel Servet, Zaragoza, Not set

China Medical University Hospital, Taichung, Not set

Division of Gastroenterology, Depart of Internal Med., Fac of Med., Chiang Mai University, Chiang Mai, Not set

Burapha University Hospital, Chonburi, Not set

Sunpasitthiprasong Hospital, Ubonratchathani, Not set

Leicester General Hospital, Leicester, Not set

Bronglais General Hospital, Llanrhystud, Not set

King College Hospital NHS Foundation Trust, London, Not set

Peterborough City Hospital, Peterborough, Not set

Stepping Hill Hospital, Stockport, Not set

New Cross Hospital, Wolverhampton, Not set

Conditions: Moderately to Severely Active Ulcerative Colitis

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Safety, Efficacy and Tolerability of Ianalumab Versus Placebo, Combination With SoC Therapy, in Participants With Active Lupus Nephritis

NCT05126277

Recruiting

This trial will evaluate efficacy, safety, and tolerability of subcutaneous (s.c.) ianalumab given every 4 weeks (q4w) or every 12 weeks (q12w) compared to placebo, in combination with SoC, in adult participants with active LN

Gender:

ALL

Ages:

Between 18 years and 100 years

Trial Updated:

07/28/2025

Locations: University Of Alabama, Birmingham, Alabama +184 locations

University Of Alabama, Birmingham, Alabama

Advanced Medical Research, La Palma, California

Wallace Rheumatic Study Center, Los Angeles, California

University of California LA, Los Angeles, California

University of California Irvine, Orange, California

UC Davis School of Medicine, Sacramento, California

University of California San Diego, San Diego, California

Kaiser Permanente, San Diego, California

Mayo Clinic Jacksonville, Jacksonville, Florida

University Of Miami, Miami, Florida

Emory University School of Medicine, Atlanta, Georgia

Fides Clinical Research, Atlanta, Georgia

Parris and Associates Rheumatology, Lawrenceville, Georgia

University of Kansas Hospital, Kansas City, Kansas

UMC New Orleans, New Orleans, Louisiana

Wayne State University, Detroit, Michigan

Univ of Nevada School of Med, Las Vegas, Nevada

Sahni Rheumatology and Therapy, West Long Branch, New Jersey

VA NM Healthcare System, Albuquerque, New Mexico

James J Peters VA Medical Center, Bronx, New York

NY Nephrology, Clifton Park, New York

Hospital for Special Surgery, New York, New York

Northwell Health, New York, New York

Circuit Clinical, Orchard Park, New York

Brookview Hills Research Assoc, Winston-Salem, North Carolina

University Of Cincinnati, Cincinnati, Ohio

Univ of Pennsylvania Medical Center, Philadelphia, Pennsylvania

Arthritis and Rheumatology Ins, Allen, Texas

Precision Comprehensive Research, Colleyville, Texas

Liberty Research Center, Dallas, Texas

Univof Texas Southwestern Med Cntr, Dallas, Texas

University of Texas Medical Branch, Galveston, Texas

Uni of Texas Health Science Center, San Antonio, Texas

Baylor Scott and White Research, Temple, Texas

Northern Assoc of Northern VA, Fairfax, Virginia

Uni Wisconsin School Med Pub Health, Madison, Wisconsin

Novartis Investigative Site, Caba, Buenos Aires

Novartis Investigative Site, Ciudad Autonoma de Bs As, Buenos Aires

Novartis Investigative Site, La Plata, Buenos Aires

Novartis Investigative Site, Ciudad Autonoma de Buenos Aire, Not set

Novartis Investigative Site, Tucuman, Not set

Novartis Investigative Site, Salvador, BA

Novartis Investigative Site, Vitoria, ES

Novartis Investigative Site, Sao Luis, Maranhao

Novartis Investigative Site, Belo Horizonte, MG

Novartis Investigative Site, Juiz de Fora, MG

Novartis Investigative Site, Curitiba, PR

Novartis Investigative Site, Pernambuco, Recife

Novartis Investigative Site, Porto Alegre, RS

Novartis Investigative Site, Santo Andre, SP

Novartis Investigative Site, Salvador, Not set

Novartis Investigative Site, Calgary, Alberta

Novartis Investigative Site, Vancouver, British Columbia

Novartis Investigative Site, Winnipeg, Manitoba

Novartis Investigative Site, Etobicoke, Ontario

Novartis Investigative Site, London, Ontario

Novartis Investigative Site, Toronto, Ontario

Novartis Investigative Site, Montreal, Quebec

Novartis Investigative Site, Sherbrooke, Quebec

Novartis Investigative Site, Santiago, RM

Novartis Investigative Site, Temuco, Not set

Novartis Investigative Site, Hefei, Anhui

Novartis Investigative Site, Guang Zhou, Guangdong

Novartis Investigative Site, Guangzhou, Guangdong

Novartis Investigative Site, Shantou, Guangdong

Novartis Investigative Site, Shenzhen, Guangdong

Novartis Investigative Site, Liuzhou, Guangxi

Novartis Investigative Site, Haikou, Hainan

Novartis Investigative Site, Wuhan, Hubei

Novartis Investigative Site, Changsha, Hunan

Novartis Investigative Site, Nanjing, Jiangsu

Novartis Investigative Site, Nanchang, Jiangxi

Novartis Investigative Site, Changchun, Jilin

Novartis Investigative Site, Shenyang, Liaoning

Novartis Investigative Site, Binzhou, Shandong

Novartis Investigative Site, Linyi, Shandong

Novartis Investigative Site, Xian, Shanxi

Novartis Investigative Site, Chengdu, Sichuan

Novartis Investigative Site, Beijing, Not set

Novartis Investigative Site, Chongqing, Not set

Novartis Investigative Site, Guang Zhou, Not set

Novartis Investigative Site, Guangzhou, Not set

Novartis Investigative Site, Shanghai, Not set

Novartis Investigative Site, Wuhan, Not set

Novartis Investigative Site, Zhejiang, Not set

Novartis Investigative Site, Medellin, Antioquia

Novartis Investigative Site, Barranquilla, Atlantico

Novartis Investigative Site, Bogota, Cundinamarca

Novartis Investigative Site, Barranquilla, Not set

Novartis Investigative Site, Olomouc, Not set

Novartis Investigative Site, Praha 2, Not set

Novartis Investigative Site, Tallinn, Not set

Novartis Investigative Site, Angers Cedex 9, Not set

Novartis Investigative Site, Besancon Cedex, Not set

Novartis Investigative Site, Bordeaux Cedex, Not set

Novartis Investigative Site, Grenoble, Not set

Novartis Investigative Site, Lyon, Not set

Novartis Investigative Site, Marseille, Not set

Novartis Investigative Site, Poitiers, Not set

Novartis Investigative Site, Regensburg, Bavaria

Novartis Investigative Site, Aachen, Not set

Novartis Investigative Site, Bochum, Not set

Novartis Investigative Site, Muenster, Not set

Novartis Investigative Site, Guatemala City, Not set

Novartis Investigative Site, Guatemala, Not set

Novartis Investigative Site, Quetzaltenango, Not set

Novartis Investigative Site, Kwun Tong, Kowloon

Novartis Investigative Site, Tuen Mun, Not set

Novartis Investigative Site, Budapest, Not set

Novartis Investigative Site, Debrecen, Not set

Novartis Investigative Site, Kaposvar, Not set

Novartis Investigative Site, Bangalore, Karnataka

Novartis Investigative Site, Secunderabad, Telangana

Novartis Investigative Site, Lucknow, Uttar Pradesh

Novartis Investigative Site, Chandigarh, Not set

Novartis Investigative Site, Cagliari, CA

Novartis Investigative Site, Foggia, FG

Novartis Investigative Site, Firenze, FI

Novartis Investigative Site, Milano, MI

Novartis Investigative Site, Pavia, PV

Novartis Investigative Site, Roma, RM

Novartis Investigative Site, Torino, TO

Novartis Investigative Site, Udine, UD

Novartis Investigative Site, Napoli, Not set

Novartis Investigative Site, Bundang Gu, Gyeonggi Do

Novartis Investigative Site, Suwon si, Gyeonggi Do

Novartis Investigative Site, Daejeon, Korea

Novartis Investigative Site, Busan, Not set

Novartis Investigative Site, Daegu, Not set

Novartis Investigative Site, Gwangju, Not set

Novartis Investigative Site, Seoul, Not set

Novartis Investigative Site, Kaunas, LTU

Novartis Investigative Site, Vilnius, Not set

Novartis Investigative Site, Sibu, Sarawak

Novartis Investigative Site, Kuala Terengganu, Terengganu

Novartis Investigative Site, Kuala Lumpur, Wilayah Persekutuan

Novartis Investigative Site, Leon, Guanajuato

Novartis Investigative Site, Monterrey, Nuevo Leon

Novartis Investigative Site, Oaxaca, Not set

Novartis Investigative Site, Queretaro, Not set

Novartis Investigative Site, Oradea, Jud Bihor

Novartis Investigative Site, Ramnicu Valcea, Valcea

Novartis Investigative Site, Bucharest, Not set

Novartis Investigative Site, Bucuresti, Not set

Novartis Investigative Site, Cluj Napoca, Not set

Novartis Investigative Site, Timisoara, Not set

Novartis Investigative Site, Singapore, Not set

Novartis Investigative Site, Barcelona, Catalunya

Novartis Investigative Site, Valencia, Comunidad Valenciana

Novartis Investigative Site, Santiago De Compostela, Galicia

Novartis Investigative Site, El Palmar, Murcia

Novartis Investigative Site, Pamplona, Navarra

Novartis Investigative Site, Vigo, Pontevedra

Novartis Investigative Site, La Laguna, Santa Cruz De Tenerife

Novartis Investigative Site, Madrid, Not set

Novartis Investigative Site, Kaohsiung, Not set

Novartis Investigative Site, Taichung, Not set

Novartis Investigative Site, Taipei, Not set

Novartis Investigative Site, Songkhla, Hat Yai

Novartis Investigative Site, Bangkok, Not set

Novartis Investigative Site, Chiang Mai, Not set

Novartis Investigative Site, Bradford, West Yorkshire

Novartis Investigative Site, London, Not set

Novartis Investigative Site, Hanoi, Not set

Novartis Investigative Site, Ho Chi Minh, Not set

Conditions: Lupus Nephritis

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