All Clinical Trials in Canada

A listing of 3904 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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A Phase 1 Study of [225Ac]-FPI-1434 Injection

NCT03746431

Recruiting

This is a first-in-human Phase 1/2, non-randomized, multi-centre, open-label clinical study designed to investigate safety, tolerability, PK, and preliminary anti-tumour activity of \[225Ac\]-FPI-1434 (radioimmuno-therapeutic agent) in patients with solid tumours that demonstrate uptake of \[111In\]-FPI-1547 (radioimmuno-imaging agent), and to establish the maximum tolerated dose (MTD) and/or the recommended Phase 2 dose (RP2D) of repeat doses of \[225Ac\]-FPI-1434 Injection in patients with sol... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/04/2025

Locations: City of Hope, Duarte, California +12 locations

Conditions: Advanced Solid Tumours, Endometrial Cancer, Cervical Cancer, Ovarian Cancer, Breast Cancer, Triple Negative Breast Cancer (TNBC), HER2-negative Breast Cancer, Head and Neck Squamous Cell Carcinoma (HNSCC), Adrenocortical Carcinoma, Uveal Melanoma

Learn More ›

A Study to Evaluate the Safety and the Activity of S095029 as Part of Combination Therapy in Advanced Gastroesophageal Junction/Gastric Cancers.

NCT06116136

Recruiting

This study will investigate the safety, tolerability, and antitumor activity of S095029 (anti-NKG2A antibody) in combination with pembrolizumab in in microsatellite instability-high/Defective mismatch repair (MSI-H/dMMR) locally advanced unresectable or metastatic gastric /GEJ adenocarcinomas.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/04/2025

Locations: Ocala Oncology Center Pl, Ocala, Florida +51 locations

Ocala Oncology Center Pl, Ocala, Florida

Investigative Clinical Research of Indiana, Llc, Noblesville, Indiana

MD Anderson Cancer Center, Houston, Texas

The Queen Elizabeth Hospital, Woodville South, Not set

Ordensklinikum Linz, Linz, Upper Austria

Med Universitat Wien-Allgemeines Krankenhaus Der Stadt Wien (AKH), Wien, Vienna

Landeskrankenhaus (SALK), Salzburg, Not set

UZ Leuven Campus Gasthuisberg, Leuven, Not set

Chu de Liege, Liège, Not set

Cepon - Centro de Pesquisas Oncologicas, Florianópolis, Not set

Supera Oncologia, Santa Catarina, Not set

Icesp - Instituto Do Câncer Do Estado de São Paulo, Sao Paulo, Not set

Instituto Brasileiro de Controle Do Câncer, Sao Paulo, Not set

Hospital Albert Einstein, Sao Paulo, Not set

Mount Sinai Hospital, Toronto, Not set

Beijing Cancer Hospital, Beijing, Beijing

Harbin Medical University Cancer Hospital, Harbin, Heilongjiang

Henan Cancer Hospital, Zhengzhou, Henan

Liaoning Cancer Hospital, Shenyang, Liaoning

Shandong Cancer Hospital Institute, Jinan, Shandong

Fudan University Shanghai Cancer Center, Shanghai, Shanghai

Sir Run Run Shaw Hospital Zhejiang University School of Medicine Qingchun Branch, Hangzhou, Zhengjiang Province

Rigshospitalet, Copenhagen, Not set

Odense Universitetshospital, Odense, Not set

Institut Bergonié, Bordeaux, Not set

Centre Georges Francois Leclerc, Dijon, Not set

Chru Lille - Hopital Claude Huriez, Lille, Not set

Inst. de Cancer de L'ouest, Saint Herblain, Not set

Institut Curie, Saint-Cloud, Not set

Institut de Cancerologie de Lorraine, Vandoeuvre-les-Nancy Cedex, Not set

Semmelweis Egyetem, Budapest, Not set

Orszagos Onkologiai Intezet, Budapest, Not set

Bekes Megyei Kozponti Korhaz, Gyula, Not set

Bugat Pal Hospital, Gyöngyös, Not set

A.O.U. Seconda Università Degli Studi Di Napoli, Campania, Not set

Fondazione IRCCS Istituto Nazionale dei Tumor, Milan, Not set

A.O.U. Pisana-Ospedale Santa Chiara, Pisa, Not set

Policlinico Universitario Agostino Gemelli, Rome, Not set

Policlinico G.B. Rossi A.O.U.I. Di Verona, Verona, Not set

Cancer Institute Hospital of Jfcr, Koto-Ku, Tokyo

National Cancer Center Hospital, Chou-ku, Not set

Osaka International Cancer Institute, Osaka, Not set

Pan American Center For Oncology Trials, Llc, Rio Piedras, Not set

University Hospital Vall D'Hebron Institute of Oncology (VHIO), Barcelona, Not set

Hospital Universitario Gregorio Marañón, Madrid, Not set

Hospital Universitario Marqués de Valdecilla, Santander, Not set

Hospital Universitario de Valencia, Valencia, Not set

The Royal Marsden in Chelsea, London, Not set

The Royal Marsden in Sutton, Sutton, Surrey, Not set

Conditions: MSI-H/dMMR Gastroesophageal-junction Cancer, MSI-H/dMMR Gastric Cancer

Learn More ›

ALT-FLOW II Trial of the Edwards APTURE Transcatheter Shunt System

NCT05686317

Recruiting

This is a prospective, multi-center, randomized, sham-controlled, double-blinded (participant and outcomes assessor) clinical trial.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/04/2025

Locations: University of California Irvine, Irvine, California +32 locations

University of California Irvine, Irvine, California

University of California San Diego, La Jolla, California

Scripps Health, La Jolla, California

University of Southern California, Los Angeles, California

University of California San Francisco, San Francisco, California

Medical Center of the Rockies, Loveland, Colorado

Ascension Illinois Heart and Vascular Medical Group, Elk Grove, Illinois

Northwestern University, Evanston, Illinois

Kansas University Medical Center, Kansas City, Kansas

Abbott Northwestern Hospital, Minneapolis, Minnesota

Mayo Clinic, Rochester, Minnesota

Montefiore Medical Center, Bronx, New York

University of Buffalo, Buffalo, New York

St. Francis Hospital & Heart Center, Roslyn, New York

The Christ Hospital, Cincinnati, Ohio

The Ohio State University, Columbus, Ohio

Oklahoma Heart Institute, Tulsa, Oklahoma

Oregon Health and Science University, Oregon City, Oregon

Lankenau Medical Center, Wynnewood, Pennsylvania

Medical University of South Carolina Charleston, Charleston, South Carolina

University of Texas Southwestern Medical Center, Dallas, Texas

HCA Houston Healthcare Medical Center, Houston, Texas

Benaroya Virginia Mason, Seattle, Washington

Instituto do Coracao da Universidade de Sao Paulo, Sao Paulo, Not set

The Ottawa Hospital, Ottawa, Not set

St. Michael's Hospital, Toronto, Not set

Herz- und Diabeteszentrum NRW - Bad Oeynhausen, Bad Oeynhausen, Not set

Herzzentrum Universitätsklinikum Köln, Cologne, Not set

Herzzentrum Dresden GmbH Universitätsklinik für Innere Medizin und Kardiologie, Dresden, Not set

Universitätsklinikum Heidelberg Medizinische Klinik, Heidelberg, Not set

Johannes Gutenberg Universitaet Mainz, Mainz, Not set

Universitätsspital Basel, Basel, Not set

Inselspital Bern, Bern, Not set

Conditions: Heart Failure

Learn More ›

A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies.

NCT06542250

Recruiting

This is a Phase I/II study designed to evaluate if experimental T cell engaging antibody targeting CD20 AZD5492 is safe, tolerable and efficacious in participants with Relapsed or Refractory B-Cell Malignancies.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/04/2025

Locations: Research Site, La Jolla, California +27 locations

Conditions: B-cell Malignancies

Learn More ›

Prospective Research Rare Kidney Stones (ProRKS)

NCT02780297

Recruiting

The purpose of this study is to determine the natural history of the hereditary forms of nephrolithiasis and chronic kidney disease (CKD), primary hyperoxaluria (PH), cystinuria, Dent disease and adenine phosphoribosyltransferase deficiency (APRTd) and acquired enteric hyperoxaluria (EH). The investigator will measure blood and urinary markers of inflammation and determine relationship to the disease course. Cross-comparisons among the disorders will allow us to better evaluate mechanisms of ren... Read More

Gender:

ALL

Ages:

All

Trial Updated:

08/02/2025

Locations: University of Alabama @ Birmingham, Birmingham, Alabama +10 locations

Conditions: Hyperoxaluria, Cystinuria, Dent Disease, Lowe Syndrome, Adenine Phosphoribosyltransferase Deficiency

Learn More ›

Optic Nerve Sheath Ultrasound in Giant Cell Arteritis

NCT05749094

Recruiting

The Sonographic Assessment of the Optic Nerve Sheath in Giant Cell Arteritis (SONIC-GCA) study will evaluate the performance of the optic nerve sheath diameter (ONSD), measured via ultrasound, to diagnose and monitor GCA. SONIC-GCA builds upon our previous pilot studies and will answer the following questions: 1. What is the performance of ONSD to identify patients with new-onset, active GCA? 2. Is ONSD useful for monitoring GCA relapses during follow-up? 3. What is the intra- and interobserver... Read More

Gender:

ALL

Ages:

Between 50 years and 99 years

Trial Updated:

08/02/2025

Locations: St-Joseph's Health Care London, London, Ontario +5 locations

Conditions: Giant Cell Arteritis, Anterior Ischemic Optic Neuropathy, Optic Neuropathy, Ischemic

Learn More ›

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

NCT06084936

Recruiting

The purpose of this study is to evaluate the efficacy of glofitamab monotherapy compared with an investigator's choice of either rituximab plus bendamustine (BR), or lenalidomide with rituximab (R-Len) in patients with relapsed or refractory (R/R) mantle cell lymphoma (MCL).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/01/2025

Locations: Alta Bates Summit Medical Center, Berkeley, California +73 locations

Alta Bates Summit Medical Center, Berkeley, California

City of Hope Cancer Center, Duarte, California

University of California Los Angeles (UCLA) - Cancer Care - Santa Monica, Santa Monica, California

Yale Cancer Center, New Haven, Connecticut

University of Miami, Coral Gables, Florida

Indiana University, Indianapolis, Indiana

University of Michigan Health System, Ann Arbor, Michigan

St. Luke's Hospital, Chesterfield, Missouri

Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey

University of Rochester, Rochester, New York

Medical University of S. Carolina, Charleston, South Carolina

Avera Cancer Institute, Sioux Falls, South Dakota

Renovatio Clinical - El Paso, El Paso, Texas

Renovatio Clinical, The Woodlands, Texas

University of Virginia, Charlottesville, Virginia

West Virginia University, Morgantown, West Virginia

Calvary Mater Newcastle, Waratah, New South Wales

Royal Adelaide Hospital, Adelaide, South Australia

Epworth Hospital, Richmond, Victoria

Hospital Sao Rafael - HSR, Salvador, Bahia

ICTR Curitiba, Curitiba, Paraná

Hospital Mae de Deus, Porto Alegre, Rio Grande Do Sul

Hospital Paulistano, Sao Paulo, São Paulo

Hospital Alemao Oswaldo Cruz, Sao Paulo, São Paulo

Hospital A. C. Camargo, Sao Paulo, São Paulo

Instituto D'Or Pesquisa e Ensino, Sao Paulo, São Paulo

Americas Medical City, Rio de Janeiro, Not set

Beneficencia Portuguesa de Sao Paulo, São Paulo, Not set

Victoria Hospital - London Health Sciences Centre, London, Ontario

The Ottawa Hospital - General Campus, Ottawa, Ontario

Princess Margaret Cancer Center, Toronto, Ontario

Beijing Tong Ren Hospital, Capital Medical University, Beijing, Not set

The First Hospital of Jilin University, Changchun City, Not set

West China Hospital of Sichuan University, Chengdu City, Not set

Chongqing Cancer Hospital, Chongqing, Not set

Fujian Provincial Cancer Hospital, Fuzhou City, Not set

Sun yat-sen University Cancer Center, Guangzhou, Not set

Guangxi Cancer Hospital of Guangxi Medical University, Nanning City, Not set

Fudan University Shanghai Cancer Center, Shanghai, Not set

The First Affiliated Hospital of China Medical University, Shenyang City, Not set

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou City, Not set

Henan Cancer Hospital, Zhengzhou City, Not set

The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Not set

Hopital Claude Huriez, Lille, Not set

Hopital Saint Eloi, Montpellier, Not set

CHU NANTES - Hôtel Dieu, Nantes, Not set

INSTITUT CURIE_SITE PARIS - Service d'Oncologie Médicale., Paris, Not set

Hopital Necker, Paris, Not set

Policlinico S.Orsola-Malpighi, Bologna, Emilia-Romagna

Humanitas Gavazzeni, Bergamo, Lombardia

Irccs Istituto Europeo Di Oncologia (IEO), Milano, Lombardia

SC Ematologia, AO SS. Antonio e Biagio e C. Arrigo, Alessandria, Piemonte

A.O. Città della Salute e della Scienza D - Osp. S. Giov. Battista Molinette, Torino, Piemonte

Chungnam National University Hospital, Daejeon, Not set

Severance Hospital, Yonsei University Health System, Seoul, Not set

Seoul National University Hospital, Seoul, Not set

Asan Medical Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Auxilio Mutuo Cancer Center, San Juan, Not set

Hospital Universitario Puerta del Mar, Cádiz, Cadiz

Hospital Universitari Vall d'Hebron, Barcelona, Not set

Hospital Clinic de Barcelona, Barcelona, Not set

Complejo Hospitalario Universitario A Coruña (CHUAC), La Coruna, Not set

Hospital General Universitario J.M Morales Meseguer, Murcia, Not set

Skånes University Hospital, Skånes Department of Onclology, Lund, Not set

Akademiska sjukhuset, Onkologkliniken, Uppsala, Not set

National Taiwan Universtiy Hospital, Taipei, Not set

Chang Gung Medical Foundation - Linkou, Taoyuan, Not set

NHS Greater Glasgow and Clyde, Glasgow, Not set

Lincolnshire County Hospital, Lincoln, Not set

University College London Hospital, London, Not set

Christie Hospital Nhs Trust, Manchester, Not set

Oxford Churchill Hospital, Oxford, Not set

Derriford Hospital, Plymouth, Not set

Conditions: Lymphoma

Learn More ›

A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)

NCT04811560

Recruiting

The purpose of this study is to determine the recommended Phase 2 dose(s) (RP2D\[s\]) of bleximenib in phase 1 Part 1 (Dose Escalation) and to determine the safety and tolerability at RP2D in Phase 1 Part 2 (Dose expansion). The purpose of the Phase 2 part of the study is to evaluate the efficacy of bleximenib at the RP2D.

Gender:

ALL

Ages:

2 years and above

Trial Updated:

08/01/2025

Locations: City of Hope, Duarte, California +96 locations

City of Hope, Duarte, California

University of California Irvine Medical Center, Orange, California

University of California San Francisco, San Francisco, California

University of Chicago, Chicago, Illinois

St Francis Hospital & Health Centers Indiana Blood and Marrow Transplantation, Indianapolis, Indiana

Norton Cancer Institute, Louisville, Kentucky

Massachusetts General Hospital, Boston, Massachusetts

Dana Farber Cancer Institute, Boston, Massachusetts

Karmanos Cancer Institute, Detroit, Michigan

Start Midwest, Grand Rapids, Michigan

University of New Mexico, Albuquerque, New Mexico

Montefiore Medical Center, Bronx, New York

Roswell Park Comprehensive Cancer Center, Buffalo, New York

NYU Langone Medical Center, New York, New York

Oregon Health And Science University, Portland, Oregon

Fox Chase Cancer Center, Philadelphia, Pennsylvania

Maine Health, Providence, Rhode Island

University of Tennessee Medical Center, Knoxville, Tennessee

Baylor University Medical Center, Dallas, Texas

Houston Methodist Hospital, Houston, Texas

MD Anderson, Houston, Texas

San Antonio Methodist TX Transplant Physicians Group, San Antonio, Texas

Virginia Commonwealth University, Richmond, Virginia

Swedish Cancer Institute, Seattle, Washington

Medical College of WI at Froedtert, Milwaukee, Wisconsin

Monash Medical Centre, Clayton, Not set

Royal Perth Hospital, Perth, Not set

Gold Coast University Hospital, Southport, Not set

Instituto D Or de Pesquisa e Ensino, Brasilia, Not set

Liga Norte Riograndense Contra O Cancer, Natal, Not set

Ministerio da Saude Instituto Nacional do Cancer, Rio de Janeiro, Not set

Instituto D Or de Pesquisa e Ensino IDOR, Sao Paulo, Not set

Vancouver Coastal Health, Vancouver, British Columbia

Princess Margaret Cancer Centre University Health Network, Toronto, Ontario

Hopital Maisonneuve Rosemont, Montreal, Quebec

Peking University First Hospital, Beijing, Not set

The First Hospital of Jilin University, Changchun, Not set

West China Hospital Si Chuan University, Chengdu, Not set

Nanfang Hospital of Southern Medical Hospital, Guangzhou, Not set

First Affiliated Hospital Medical School of Zhejiang University, Hang Zhou, Not set

Qilu Hospital of Shandong University, Jinan, Not set

The First Affiliated Hospital of NanChang University, Nanchang, Not set

Zhongda Hospital Southeast University, Nanjing, Not set

Institute of Hematology and Blood Diseases Hospital, Tianjin, Not set

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Not set

Union Hospital Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Not set

Henan Cancer Hospital, Zheng Zhou Shi, Not set

Hopital Jean Minjoz, Besancon, Not set

Institut Paoli Calmettes, Marseille, Not set

CHU de Nantes hotel Dieu, Nantes Cedex 1, Not set

Hopital Saint Louis, Paris, Not set

Hopital trousseau- APHP, Paris, Not set

Centre Hospitalier Universitaire (CHU) de Bordeaux Hopital HautLeveque Centre Francois Magendie, Pessac, Not set

CHU Lyon Sud, Pierre Benite, Not set

Institut de Cancerologie Strasbourg Europe ICANS, Strasbourg, Not set

Institut Universitaire du Cancer Toulouse Oncopole, Toulouse, Not set

CHU Bretonneau, Tours cedex, Not set

CHRU Nancy Brabois, Vandoeuvre les Nancy, Not set

Gustave Roussy, Villejuif, Not set

Carmel Medical Center, Haifa, Not set

Hadassah University Hospita Ein Kerem, Jerusalem, Not set

Sheba Medical Center, Ramat Gan, Not set

Tel Aviv Sourasky Medical Center, Tel Aviv Yafo, Not set

Kyushu University Hospital, Fukuoka, Not set

Fukushima Medical University Hospital, Fukushima, Not set

Kanazawa University Hospital, Kanazawa, Not set

National Cancer Center Hospital East, Kashiwa, Not set

Kobe City Medical Center General Hospital, Kobe City, Not set

Gunmaken Saiseikai Maebashi Hospital, Maebashi, Not set

Nagoya University Hospital, Nagoya, Not set

Hokkaido University Hospital, Sapporo, Not set

NTT Medical Center Tokyo, Tokyo, Not set

Yamagata University Hospital, Yamagata, Not set

University of Fukui Hospital, Yoshida, Not set

Seoul National University Hospital, Seoul, Not set

Asan Medical Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Hosp Univ Vall D Hebron, Barcelona, Not set

Hosp Clinic de Barcelona, Barcelona, Not set

Hosp. Gral. Univ. Gregorio Maranon, Madrid, Not set

Hosp Univ Fund Jimenez Diaz, Madrid, Not set

Clinica Univ. de Navarra, Pamplona, Not set

Hosp Clinico Univ de Salamanca, Salamanca, Not set

Hosp. Virgen Del Rocio, Sevilla, Not set

Hosp. Clinico Univ. de Valencia, Valencia, Not set

China Medical University Hospital, Taichung, Not set

National Cheng Kung University Hospital, Tainan, Not set

National Taiwan University Hospital, Taipei, Not set

University Hospital of Wales, Cardiff, Not set

Leeds Teaching Hospitals NHS Trust, Leeds, Not set

The Clatterbridge Cancer Centre, Liverpool, Not set

Guys and St Thomas NHS Foundation Trust, London, Not set

University College London Hospitals, London, Not set

The Christie Nhs Foundation Trust, Manchester, Not set

Oxford University Hospitals NHS Trust, Oxfordshire, Not set

University Hospitals Plymouth NHS Trust, Plymouth, Not set

Conditions: Acute Leukemias, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia

Learn More ›

An Open-Label Study Comparing Glofitamab and Polatuzumab Vedotin + Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone Versus Pola-R-CHP in Previously Untreated Patients With Large B-Cell Lymphoma

NCT06047080

Recruiting

The purpose of this study is to compare the efficacy and safety of glofitamab in combination with polatuzumab vedotin plus rituximab, cyclophosphamide, doxorubicin, and prednisone (Pola-R-CHP) vs Pola-R-CHP in participants with previously untreated CD20-positive large B-cell lymphoma (LBCL).

Gender:

ALL

Ages:

Between 18 years and 80 years

Trial Updated:

08/01/2025

Locations: Alaska Oncology & Hematology, LLC, Anchorage, Alaska +273 locations

Alaska Oncology & Hematology, LLC, Anchorage, Alaska

Kaiser Permanente - Anaheim (E. La Palma), Anaheim, California

University of California, San Francisco-Fresno, Clovis, California

City of Hope National Medical Center, Duarte, California

City of Hope - Lennar Foundation Cancer Center, Irvine, California

Scripps Clinic Torrey Pines, La Jolla, California

Valkyrie Clinical Trials, Los Angeles, California

UCLA Jonsson Comprehensive Cancer Center, Los Angeles, California

Kaiser Permanente - Oakland, Oakland, California

Kaiser Permanente - Roseville, Roseville, California

Kaiser Permanente - San Francisco (2238 Geary), San Francisco, California

Kaiser Permanente - Santa Clara, Santa Clara, California

Stanford Univ School of Med, Stanford, California

Kaiser Permanente Medical Ctr, Vallejo, California

Kaiser Permanente - Walnut Creek, Walnut Creek, California

University of Colorado Cancer Center, Aurora, Colorado

Rocky Mountain Cancer Center - Denver, Littleton, Colorado

Yale University School Of Medicine, New Haven, Connecticut

Medstar Franklin Square Medical Center, Washington, District of Columbia

Miami Cancer Institute of Baptist Health, Inc., Miami, Florida

Memorial Cancer Institute at Memorial West, Pembroke Pines, Florida

Hawaii Cancer Care, Honolulu, Hawaii

Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois

NorthShore Center for Advanced Imaging, Evanston, Illinois

Illinois Cancer Care, Peoria, Illinois

Springfield Clinic, Springfield, Illinois

University of Iowa, Iowa City, Iowa

Ascension Via Christi Research, Wichita, Kansas

Ochsner Medical Center, New Orleans, Louisiana

Louisiana State University Health Sciences Center, Shreveport, Louisiana

Massachusetts General Hospital, Boston, Massachusetts

Dana Farber Cancer Institute, Boston, Massachusetts

Boston Medical Center, Boston, Massachusetts

Beth Israel Deaconess Medical Center, Boston, Massachusetts

Karmanos Cancer Institute, Detroit, Michigan

Henry Ford Health System, Novi, Michigan

M Health Fairview University of Minnesota Medical Center, Minneapolis, Minnesota

St. Luke's Hospital, Chesterfield, Missouri

University of Missouri Health Care, Columbia, Missouri

Washington University School of Medicine, Saint Louis, Missouri

St. Vincent Frontier Cancer Center, Billings, Montana

University of Nebraska Medical Center, Omaha, Nebraska

MSKCC at Basking Ridge, Basking Ridge, New Jersey

Astera Cancer Care East Brunswick, East Brunswick, New Jersey

MSK Monmouth, Middletown, New Jersey

MSK Bergen, Montvale, New Jersey

Montefiore Medical Center - Montefiore Medical Park, Bronx, New York

Montefiore Medical Center, Bronx, New York

New York Cancer & Blood Specialists, Bronx, New York

NYU Langone Hospital?Brooklyn, Brooklyn, New York

MSK Commack, Commack, New York

Memorial Sloan Kettering Cancer Center, Harrison, New York

NYU Long Island Hospital, Mineola, New York

New York Cancer and Blood Specialists - New Hyde Park, New Hyde Park, New York

New York University Medical Center PRIME, New York, New York

Memorial Sloan Kettering Cancer Center David H Koch Center for Cancer Care, New York, New York

Weill Cornell Medical College-New York Presbyterian Hospital, New York, New York

New York Cancer and Blood Specialists-Central Park Hematology & Oncology, New York, New York

University of Rochester Medical Center, Rochester, New York

North Shore Hematology Oncology Association PC, Shirley, New York

MSK Nassau, Uniondale, New York

University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

Levine Cancer Institute, Charlotte, North Carolina

Sanford Roger Maris Cancer Center, Fargo, North Dakota

Oncology Hematology Care Inc - Cincinnati - USOR, Cincinnati, Ohio

Willamette Valley Cancer Insitute and Research Center, Springfield, Oregon

Kimmel Cancer Center Thomas Jefferson University, Philadelphia, Pennsylvania

Fox Chase Cancer Center, Philadelphia, Pennsylvania

West Penn Hospital, Pittsburgh, Pennsylvania

Avera Cancer Institute, Sioux Falls, South Dakota

Greco-Hainesworth Tennessee Oncology Centers for Research, Chattanooga, Tennessee

West Cancer Center & Research Institute, Germantown, Tennessee

SCRI Oncology Partners, Nashville, Tennessee

Tennessee Oncology, Nashville, Tennessee

Texas Oncology - Baylor Charles A. Sammons Cancer Center, Dallas, Texas

Texas Oncology, Fort Worth, Texas

Harris Health System Smith Clinic, Houston, Texas

O'Quinn Medical Tower at McNair Campus, Houston, Texas

USOR - Texas Oncology - San Antonio Northeast, San Antonio, Texas

University of Vermont, Burlington, Vermont

Virginia Cancer Specialists, Fairfax, Virginia

Virginia Oncology Associates, Newport News, Virginia

Swedish Cancer Institute - Edmonds Campus, Edmonds, Washington

Swedish Cancer Institute - Issaquah, Issaquah, Washington

Swedish Medical Center, Seattle, Washington

University of Washington - Seattle Cancer Care Alliance, Seattle, Washington

West Virginia University, Morgantown, West Virginia

Univ of Wisconsin Hosp & Clin, Madison, Wisconsin

Instituto Alexander Fleming, Buenos Aires, Not set

FUNDALEU, Buenos Aires, Not set

Hospital Aleman de Buenos Aires, Buenos Aires, Not set

Sanatorio Allende, Cordoba, Not set

Hospital Austral, Pilar, Not set

Concord Repatriation General Hospital, Concord, New South Wales

Prince of Wales Hospital- Department of Hematology, Randwick, New South Wales

Townsville Hospital, Douglas, Queensland

Princess Alexandra Hospital Woolloongabba, Woolloongabba, Queensland

Flinders Medical Centre, Bedford Park, South Australia

Royal Hobart Hospital, Hobart, Tasmania

Eastern Health, Box Hill, Victoria

St Vincent's Hospital Melbourne, Fitzroy, Victoria

Barwon Health, Geelong, Victoria

Peter Maccallum Cancer Centre, Melbourne, Victoria

Sir Charles Gairdner Hospital, Nedlands, Western Australia

Institut Jules Bordet, Anderlecht, Not set

UZ Brussel, Brussel, Not set

UZ Antwerpen, Edegem, Not set

UZ Gent, Gent, Not set

AZ Groeninge, Kortrijk, Not set

CHU de Liège (Sart Tilman), Liège, Not set

Hospital Erasto Gaertner, Curitiba, Paraná

Instituto D'Or Pesquisa e Ensino, Sao Paulo, São Paulo

Hospital das Clinicas - FMUSP, Oncologia, Sao Paulo, São Paulo

Eastern Health - General Hospital, St. John's, Newfoundland and Labrador

Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia

Royal Victoria Regional Health Centre, Barrie, Ontario

William Osler Health Centre - Brampton Civic Hospital, Brampton, Ontario

The Ottawa Hospital - General Campus, Ottawa, Ontario

Health Sciences North, Sudbury, Ontario

Princess Margaret Cancer Centre, Toronto, Ontario

Centre Hospitalier de l'Universite de Montreal (CHUM), Montreal, Quebec

CHA Hopital de I enfant-Jesus, Quebec City, Quebec

Centre Integre Universitaire de Sante et de Services Sociaux de la Mauricie-et-du-Centre-du-Quebec, Trois-rivieres, Quebec

Beijing Cancer Hospital, Beijing, Not set

Peking University Third Hospital, Beijing, Not set

The First Hospital of Jilin University, Changchun City, Not set

Hunan Cancer Hospital, Changsha CITY, Not set

West China Hospital, Sichuan University, Chengdu, Not set

Sichuan Provincial People's Hospital, Chengdu, Not set

Second Affiliated Hospital of Third Military Medical University, Chongqing, Not set

Fujian Cancer Hospital, Fuzhou, Not set

Southern Medical University Nanfang Hospital, Guangdong Province Guangzhou City, Not set

Sun yat-sen University Cancer Center, Guangzhou, Not set

Zhujiang Hospital, Southern Medical University, Guangzhou, Not set

Harbin Medical University Cancer Hospital, Harbin, Not set

Anhui Province Cancer Hospital, Hefei City, Not set

Shandong Cancer Hospital, Jinan, Not set

Jiangxi Cancer Hospital, Nanchang City, Not set

Jiangsu Cancer Hospital, Nanjing City, Not set

Guangxi Cancer Hospital of Guangxi Medical University, Nanning, Not set

Fudan University Shanghai Cancer Center, Shanghai City, Not set

Shengjing Hospital of China Medical University, Shenyang City, Not set

First Hospital of China Medical University, Shenyang, Not set

First Affiliated Hospital of Soochow University, Suzhou, Not set

Institute of Hematology and Blood Diseases Hospital Chinese Academy of Medical Sciences, Tianjin City, Not set

Tianjin Cancer Hospital, Tianjin, Not set

Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan City, Not set

Tongji Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan City, Not set

The First Affiliated Hospital of Xiamen University, Xiamen, Not set

The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Not set

Aalborg Universitetshospital, Aalborg, Not set

Aarhus Universitetshospital Skejby, Aarhus N, Not set

Regionshospitalet Gødstrup, Herning, Not set

CHRU de Lille - Hopital Claude Huriez, Lille, Not set

Hospices Civils de Lyon, Lyon, Not set

Institut Paoli Calmettes, Marseille, Not set

CHU Montpellier, Montpellier, Not set

CHU de Nantes - Hotel Dieu, Nantes, Not set

CHU de Bordeaux, Pessac, Not set

CHU DE RENNES - CHU Pontchaillou, Rennes, Not set

Centre Henri Becquerel, Rouen, Not set

CHU Strasbourg Hpital Hautepierre, Strasbourg, Not set

IUCT Oncopole, Toulouse, Not set

Charité Universitätsmedizin Berlin, Berlin, Not set

Staedisches Klinikum Brandenburg, Brandenburg an der Havel, Not set

Klinikum Chemnitz gGmbH, Klinik f. Innere Medizin III, Chemnitz, Not set

Universitätsklinikum Düsseldorf, Düsseldorf, Not set

Universitätsklinikum Erlangen, Medizinische Klinik 5, Hämatologie und Internistische Onkologie, Erlangen, Not set

Universitätsklinikum Essen, Essen, Not set

Universitätsklinikum Frankfurt, Frankfurt, Not set

UKE Universitätsklinikum Hamburg-Eppendorf, Hamburg, Not set

Westpfalz-Klinikum GmbH, Kaiserslautern, Not set

Städtisches Krankenhaus Kiel GmbH, Kiel, Not set

Universitätsklinikum Köln, Koeln, Not set

Universitaetsklinikum Schleswig Holstein - Campus Luebeck, Luebeck, Not set

Otto von Guericke Uni Magdeburg Uniklinik, Magdeburg, Not set

Klinikum rechts der Isar der TU München, III. Medizinische Klinik, München, Not set

Universitätsklinikum Münster, Münster, Not set

Klinikum Ernst von Bergman, Potsdam, Not set

Universitaet Rostock, Zentrum Innere Medizin, Rostock, Not set

Klinikum Stuttgart Katharinenhospital, Stuttgart, Not set

Universitätsklinikum Ulm, Ulm, Not set

Universitätsklinikum Würzburg, Würzburg, Not set

Istituto Nazionale Tumori Irccs Fondazione g. Pascale, Napoli, Campania

Policlinico S.Orsola-Malpighi, Bologna, Emilia-Romagna

A.O. Universitaria Policlinico Di Modena, Modena, Emilia-Romagna

A.O. Universitaria S. Martino Di Genova, Genova, Liguria

Asst Papa Giovanni Xxiii, Bergamo, Lombardia

Fond. IRCCS Istituto Nazionale Tumori, Milano, Lombardia

Istituto Clinico Humanitas, Rozzano, Lombardia

A. O. U. Policlinico G. Rodolico, Catania, Sicilia

USL 4 di Prato - Nuovo Ospeale di Prato, Prato, Toscana

Ospedale San Bortolo, Vicenza, Veneto

Anjo Kosei Hospital, Aichi, Not set

Aichi Cancer Center, Aichi, Not set

Nagoya University Hospital, Aichi, Not set

Chiba Cancer Center, Chiba, Not set

National Cancer Center Hospital East, Chiba, Not set

National Hospital Organization Kyushu Cancer Center, Fukuoka, Not set

Kyushu University Hospital, Fukuoka, Not set

Gifu University Hospital, Gifu, Not set

Hokkaido University Hospital, Hokkaido, Not set

Kobe City Medical Center General Hospital, Hyogo, Not set

Kanagawa Cancer Center, Kanagawa, Not set

Tokai University Hospital, Kanagawa, Not set

University Hospital Kyoto Prefectural University of Medicine, Kyoto, Not set

Tohoku University Hospital, Miyagi, Not set

Okayama University Hospital, Okayama, Not set

Osaka Metropolitan University Hospital, Osaka, Not set

Kansai Medical University Hospital, Osaka, Not set

Kindai University Hospital, Osaka, Not set

Shimane University Hospital, Shimane, Not set

National Cancer Center Hospital, Tokyo, Not set

Komagome Hospital, Tokyo, Not set

The Cancer Institute Hospital of JFCR, Tokyo, Not set

Keio University Hospital, Tokyo, Not set

Yamagata University Hospital, Yamagata, Not set

Inje university Haeundae Paik Hospital, Busan, Not set

Pusan National University Hospital, Busan, Not set

Keimyung University Dongsan Medical Center, Daegu, Not set

Chungnam National University Hospital, Daejeon, Not set

National Cancer Center, Goyang-si, Not set

Chonnam National University Hwasun Hospital, Jeollanam-do, Not set

Korea University Anam Hospital, Seoul, Not set

Seoul National University Hospital, Seoul, Not set

Severance Hospital, Seoul, Not set

Asan Medical Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Seoul St Mary's Hospital, Seoul, Not set

Yeouido St. Mary's Hospital, Seoul, Not set

Health Pharma Professional Research, Cdmx, Mexico CITY (federal District)

Inst. Nacional de Cancerologia, Mexico City, Mexico CITY (federal District)

Hospital General de Mexico, Mexico, Tlaxcala

Hospital de Especialidades Centro Medico Nacional La Raza, Mexico City, Not set

Szpital Specjalistyczny Podkarpacki O?rodek Onkologiczny, Brzozów, Not set

Uniwersyteckie Centrum Kliniczne, Gda?sk, Not set

Pratia Onkologia Katowice, Katowice, Not set

?wi?tokrzyskie Centrum Onkologii SPZOZ, Kielce, Not set

PRATIA MCM Kraków, Kraków, Not set

Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wroclawiu, Wroc?aw, Not set

Auxilio Mutuo Cancer Center, San Juan, Not set

Complejo Hospitalario Universitario de Santiago (CHUS), Santiago de Compostela, LA Coruna

Hospital Quiron de Madrid, Pozuelo de Alarcon, Madrid

Clinica Universitaria de Navarra, Pamplona, Navarra

Hospital Universitari Vall d'Hebron, Barcelona, Not set

Hospital General Universitario Gregorio Marañon, Madrid, Not set

Clinica Universidad de Navarra Madrid, Madrid, Not set

Hospital Universitario Virgen del Rocio, Sevilla, Not set

Hospital Clinico Universitario de Valencia, Valencia, Not set

Universitaetsspital Basel, Basel, Not set

Chang Gung Medical Foundation - Chai Yi, Chai Yi, Not set

Chang Gung Medical Foundation - Kaohsiung;Oncology, Kaoisung, Not set

E-Da Cancer Hospital, Kaoshiung, Not set

China Medical University Hospital, Taichung, Not set

Chi-Mei Hospital, Liouying, Tainan, Not set

National Taiwan University Hospital, Taipei, Not set

Abdurrahman Yurtarslan Onkoloji Training and Research Hospital, Ankara, Not set

Ankara Universitesi Tip Fakultesi Hastaneleri - Cebeci Hastanesi, Ankara, Not set

Istanbul VKV American Hospital, Istanbul, Not set

Marmara University Pendik Training and Research Hospital, Istanbul, Not set

Kocaeli Univesity Medical Faculty, Izmit, Not set

Barnet Hospital, Barnet, Not set

Blackpool Victoria Hospital, Blackpool, Not set

East Kent Hospitals University NHS Foundation Trust, Canterbury, Not set

Royal Devon and Exeter Hospital, Exeter, Not set

Beatson West of Scotland Cancer Centre, Glasgow, Not set

Leeds Teaching Hosp NHS Trust, Leeds, Not set

Leicester Royal Infirmary, Leicester, Not set

University College London Hospitals NHS Foundation Trust - University College Hospital, London, Not set

Guy'S Hospital, London, Not set

Newcastle University, Newcastle, Not set

Nottingham University Hospitals NHS Trust, Nottingham, Not set

Churchill Hospital - Oxford Cancer & Haematology Centre, Oxford, Not set

Southampton General Hospital, Southampton, Not set

Conditions: Large B-Cell Lymphoma

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Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)

NCT06596694

Recruiting

Researchers want to learn if patritumab deruxtecan (MK-1022) can treat certain gastrointestinal (GI) cancers. The GI cancers being studied are advanced (the cancer has spread to other parts of the body). The goals of this study are to learn: * About the safety and how well people tolerate of patritumab deruxtecan * How many people have the cancer respond (get smaller or go away) to treatment

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/01/2025

Locations: UCLA Hematology Oncology Santa Monica ( Site 1205), Santa Monica, California +60 locations

UCLA Hematology Oncology Santa Monica ( Site 1205), Santa Monica, California

University of Colorado Cancer Center ( Site 1200), Aurora, Colorado

Sibley Memorial Hospital ( Site 1208), Washington, District of Columbia

University of Florida ( Site 1202), Gainesville, Florida

Mount Sinai Medical Center Comprehensive Cancer Center ( Site 1213), Miami Beach, Florida

Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital-Research ( Site 1203), Marietta, Georgia

University of Chicago Medical Center ( Site 1204), Chicago, Illinois

Renown Regional Medical Center ( Site 1221), Reno, Nevada

NYU Langone Hospital - Long Island ( Site 1230), Mineola, New York

Perlmutter NYU Cancer Center ( Site 1212), New York, New York

Scott & White Medical Center-Temple ( Site 1224), Temple, Texas

Oncology and Hematology Associates of Southwest Virginia (BRCC) ( Site 1207), Roanoke, Virginia

University of Wisconsin ( Site 1210), Madison, Wisconsin

Westmead Hospital ( Site 0100), Sydney, New South Wales

Alfred Health ( Site 0102), Melbourne, Victoria

Austin Health ( Site 0103), Melbourne, Victoria

One Clinical Research ( Site 0104), Mount Pleasant, Western Australia

QEII Health Sciences Centre - Victoria General Site ( Site 0200), Halifax, Nova Scotia

McGill University Health Centre ( Site 0202), Montreal, Quebec

Fundacion Arturo Lopez Perez ( Site 0301), Santiago., Region M. De Santiago

Centro de Oncología de Precisión ( Site 0305), Santiago, Region M. De Santiago

Clínica UC San Carlos de Apoquindo ( Site 0302), Santiago, Region M. De Santiago

Bradfordhill ( Site 0300), Santiago, Region M. De Santiago

The First Affiliated Hospital of Anhui Medical University ( Site 0405), Hefei, Anhui

Fujian Provincial Cancer Hospital ( Site 0408), Fuzhou, Fujian

Zhongshan Hospital Fudan University (Xiamen Branch) ( Site 0412), Xiamen, Fujian

Southern Medical University Nanfang Hospital ( Site 0413), Fuzhou, Guangdong

The First Affiliated Hospital, Sun Yat-sen University ( Site 0404), Guangzhou, Guangdong

Affiliated Cancer Hospital of Guangxi Medical University ( Site 0411), Nanning, Guangxi

Henan Cancer Hospital ( Site 0403), Zhengzhou, Henan

Zhongshan Hospital,Fudan University ( Site 0400), Shanghai, Shanghai

First Hospital of Shanxi Medical University ( Site 0409), Tai Yuan, Shanxi

Hopital Beaujon ( Site 0500), Clichy, Hauts-de-Seine

Centre Eugène Marquis Rennes - Centre de Lutte Contre le Cancer ( Site 0501), Rennes, Ille-et-Vilaine

Hopital de la Croix Rousse ( Site 0502), Lyon, Rhone-Alpes

Rambam Health Care Campus ( Site 0603), Haifa, Not set

Sourasky Medical Center ( Site 0601), Tel Aviv, Not set

Hadassah Medical Center ( Site 0602), Yerushalayim, Not set

Fondazione IRCCS Istituto Nazionale dei Tumori ( Site 0700), Milano, Not set

ASST Grande Ospedale Metropolitano Niguarda ( Site 0701), Milano, Not set

Fondazione Policlinico Universitario Agostino Gemelli ( Site 0702), Roma, Not set

Seoul National University Hospital ( Site 0900), Seodaemun-gu, Seoul

Severance Hospital, Yonsei University Health System ( Site 0903), Seoul, Not set

Asan Medical Center ( Site 0902), Seoul, Not set

Samsung Medical Center ( Site 0901), Seoul, Not set

Harbour Cancer & Wellness ( Site 0800), Auckland, Not set

Hospital Central de Asturias ( Site 1001), Oviedo, Asturias

Hospital Universitari Vall d'Hebron ( Site 1000), Barcelona, Not set

Hospital Universitario Gregorio Maranon ( Site 1002), Madrid, Not set

Hospital Clinico San Carlos... ( Site 1003), Madrid, Not set

Hopitaux Universitaires de Geneve HUG. ( Site 1102), Geneve, Not set

Universitaetsspital Zuerich ( Site 1105), Zurich, Not set

National Cheng Kung University Hospital-Clinical Trial Center ( Site 1502), Tainan, Not set

National Taiwan University Hospital ( Site 1500), Taipei, Not set

Taipei Veterans General Hospital ( Site 1501), Taipei, Not set

Faculty of Medicine Siriraj Hospital ( Site 1301), Bangkoknoi, Krung Thep Maha Nakhon

Ramathibodi Hospital ( Site 1302), Ratchathewi, Krung Thep Maha Nakhon

Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastırma Hastanesi ( Site 1400), Yenimahalle, Ankara

Dokuz Eylul Universitesi Hastanesi ( Site 1402), Balcova, Izmir

Adana City Hospital ( Site 1404), Adana, Not set

Hacettepe Universite Hastaneleri ( Site 1401), Ankara, Not set

Conditions: Gastrointestinal Cancer

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A Study to Assess the Efficacy and Safety of Emicizumab in Participants With Type 3 Von Willebrand Disease

NCT06998524

Recruiting

This is a Phase III, multicenter, open-label clinical study designed to evaluate the efficacy, safety, pharmacokinetics, and pharmacodynamics of emicizumab prophylaxis in participants aged 2 years and above, who have been diagnosed with Type 3 von Willebrand disease (VWD). Participants on prior standard of care (SOC) on-demand therapy will be assessed via a randomized comparison (Arm A - emicizumab prophylaxis and Arm B - continuation of SOC on-demand therapy), while participants on prior SOC pr... Read More

Gender:

ALL

Ages:

2 years and above

Trial Updated:

08/01/2025

Locations: UZ Leuven Gasthuisberg, Leuven, Not set +8 locations

Conditions: Von Willebrand Disease, Type 3

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A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of RO7589831 as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors

NCT06004245

Recruiting

This is a first-in-human, Phase I, open-label, multicenter, dose-escalation and dose expansion study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary anti-tumor activity of RO7589831 monotherapy, and in combination with pembrolizumab, in participants with microsatellite instability (MSI) and/or deficient mismatch repair (dMMR) advanced solid tumors. RO7589831 is an oral drug that acts on a protein called Werner (WRN), which may promote the growth of cance... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/01/2025

Locations: City of Hope Cancer Center, Duarte, California +24 locations

Conditions: Advanced Solid Tumors

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