All Clinical Trials in Canada

A listing of 3904 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation

NCT04449874

Recruiting

This is a Phase I dose-escalation and dose-expansion study that will evaluate the safety, pharmacokinetics (PK), and preliminary activity of GDC-6036 in patients with advanced or metastatic solid tumors with a KRAS G12C mutation.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/01/2025

Locations: City of Hope Comprehensive Cancer Center, Duarte, California +73 locations

City of Hope Comprehensive Cancer Center, Duarte, California

UCSD Moores Cancer Center, La Jolla, California

Chao Family Comprehensive Cancer Center UCI, Orange, California

Univ of Calif, San Francisco, San Francisco, California

Yale Cancer Center, New Haven, Connecticut

Florida Cancer Specialists - Sarasota, Sarasota, Florida

Dana Farber Cancer Institute, Boston, Massachusetts

Memorial Sloan Kettering Cancer Center, New York, New York

University of Oklahoma, Oklahoma City, Oklahoma

Abramson Cancer Center, Philadelphia, Pennsylvania

UPMC - Hillman Cancer Center, Pittsburgh, Pennsylvania

St Vincent's Hospital Sydney, Darlinghurst, New South Wales

Slade Health Inward goods, Mount Kuring-gai, New South Wales

Peter MacCallum Cancer Center, Melbourne, Victoria

Alfred Health, Melbourne, Victoria

Linear Clinical Research Limited, Nedlands, Western Australia

UZ Antwerpen, Edegem, Not set

CHU de Liège, Liège, Not set

AZ St Maarten Campus Leopoldstr, Mechelen, Not set

Santa Casa de Misericordia de Belo Horizonte - PPDS, Belo Horizonte, Minas Gerais

Hospital Erasto Gaertner, Curitiba, Paraná

Hospital de Clinicas de Porto Alegre HCPA PPDS, Porto Alegre, Pará

Universidade de Caxias do Sul, Caxias Do Sul, Rio Grande Do Sul

Hospital Sao Lucas Da Pontificia Universidade Catolica Do Rio Grande Do Sul (PUCRS), Porto Alegre, Rio Grande Do Sul

Hospital de Cancer de Barretos, Barretos, São Paulo

Fundacao Faculdade Regional de Medicina de Sao Jose Do Rio Preto Hospital de Base - PPDS, Sao Jose Do Rio Preto, São Paulo

Instituto do Cancer do Estado de Sao Paulo - ICESP, Sao Paulo, São Paulo

Instituto Nacional de Câncer, Rio de Janeiro, Not set

Ottawa Hospital, Ottawa, Ontario

Princess Margaret Cancer Centre, Toronto, Ontario

Jewish General Hospital, Montreal, Quebec

Semmelweis Egyetem, Budapest, Not set

Clinexpert Gyongyos Kft, Gyöngyös, Not set

Rambam Medical Center, Haifa, Not set

Sheba Medical Center - PPDS, Ramat Gan, Not set

Tel-Aviv Sourasky Medical Center, Tel Aviv, Not set

Istituto Scientifico Romagnolo Per Lo Studio E La Cura Dei Tumori IRST - PPDS, Meldola, Emilia-Romagna

Irccs Ospedale San Raffaele, Milano, Lombardia

Asst Grande Ospedale Metropolitano Niguarda, Milano, Lombardia

Istituto Clinico Humanitas, Rozzano (MI), Lombardia

Azienda Ospedaliero Universitaria Pisana, Pisa, Toscana

Aga Khan University Hospital, Nairobi, Not set

Seoul National University Bundang Hospital, Seongnam-si, Not set

Seoul National University Hospital, Seoul, Not set

Asan Medical Center - PPDS, Seoul, Not set

Samsung Medical Center - PPDS, Seoul, Not set

Het Nederlands Kanker Instituut Antoni Van Leeuwenhoek Ziekenhuis, Amsterdam, Not set

Leids Universitair Medisch Centrum, Leiden, Not set

Maastricht University Medical Center, Maastricht, Not set

Universitair Medisch Centrum Utrecht, Utrecht, Not set

Auckland City Hospital, Cancer and Blood Research, Auckland, Not set

Auckland City Hospital, Auckland, Not set

New Zealand Clinical Research - Christchurch, Christchurch, Not set

Haukeland University Hospital, Bergen, Not set

Oslo university hospital Radiumhospitalet, Oslo, Not set

Uniwersyteckie Centrum Kliniczne, O?rodek Bada? Klinicznych Wczesnych Faz, Gdansk, Not set

Biokinetica, Przychodnia Jozefow, Jozefow, Not set

Uniwersytecki Szpital Kliniczny w Poznaniu, Pozna?, Not set

Republican Clinical Oncology Dispensary of Ministry of Healthcare of Tatarstan Republic, Kazan, Tatarstan

Hospital Universitari Vall d'Hebron, Barcelona, Not set

START Madrid-FJD, Hospital Fundacion Jimenez Diaz, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Hospital Universitario HM Sanchinarro-CIOCC, Madrid, Not set

Hospital Clinico Universitario Virgen de la Victoria, Malaga, Not set

Hospital Universitario Virgen del Rocío, Sevilla, Not set

Hospital Clinico Universitario de Valencia, Valencia, Not set

Universitaetsspital Basel, Basel, Not set

Inselspital, Bern, Not set

Hôpitaux Universitaires de Genève, Genève, Not set

Unversitätsspital Zürich, Zürich, Not set

Queen Elizabeth Hospital, Birmingham, Not set

Velindre Cancer Centre, Cardiff, Not set

University College London Hospitals NHS Foundation Trust, London, Not set

The Christie NHS Foundation Trust, Manchester, Not set

Conditions: Non-Small Cell Lung Cancer, Colorectal Cancer, Advanced Solid Tumors

Learn More ›

Evaluation of In-lab Benefit for Speech-in-noise Intelligibility With Device for Adults With Mild to Moderate Hearing Loss

NCT07074769

Recruiting

Evaluation of in-lab benefit for speech-in-noise intelligibility with the device for adults with mild to moderate hearing loss.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/01/2025

Locations: Western University, London, Ontario

Conditions: Hearing Loss

Learn More ›

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

NCT06084936

Recruiting

The purpose of this study is to evaluate the efficacy of glofitamab monotherapy compared with an investigator's choice of either rituximab plus bendamustine (BR), or lenalidomide with rituximab (R-Len) in patients with relapsed or refractory (R/R) mantle cell lymphoma (MCL).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/01/2025

Locations: Alta Bates Summit Medical Center, Berkeley, California +73 locations

Alta Bates Summit Medical Center, Berkeley, California

City of Hope Cancer Center, Duarte, California

University of California Los Angeles (UCLA) - Cancer Care - Santa Monica, Santa Monica, California

Yale Cancer Center, New Haven, Connecticut

University of Miami, Coral Gables, Florida

Indiana University, Indianapolis, Indiana

University of Michigan Health System, Ann Arbor, Michigan

St. Luke's Hospital, Chesterfield, Missouri

Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey

University of Rochester, Rochester, New York

Medical University of S. Carolina, Charleston, South Carolina

Avera Cancer Institute, Sioux Falls, South Dakota

Renovatio Clinical - El Paso, El Paso, Texas

Renovatio Clinical, The Woodlands, Texas

University of Virginia, Charlottesville, Virginia

West Virginia University, Morgantown, West Virginia

Calvary Mater Newcastle, Waratah, New South Wales

Royal Adelaide Hospital, Adelaide, South Australia

Epworth Hospital, Richmond, Victoria

Hospital Sao Rafael - HSR, Salvador, Bahia

ICTR Curitiba, Curitiba, Paraná

Hospital Mae de Deus, Porto Alegre, Rio Grande Do Sul

Hospital Paulistano, Sao Paulo, São Paulo

Hospital Alemao Oswaldo Cruz, Sao Paulo, São Paulo

Hospital A. C. Camargo, Sao Paulo, São Paulo

Instituto D'Or Pesquisa e Ensino, Sao Paulo, São Paulo

Americas Medical City, Rio de Janeiro, Not set

Beneficencia Portuguesa de Sao Paulo, São Paulo, Not set

Victoria Hospital - London Health Sciences Centre, London, Ontario

The Ottawa Hospital - General Campus, Ottawa, Ontario

Princess Margaret Cancer Center, Toronto, Ontario

Beijing Tong Ren Hospital, Capital Medical University, Beijing, Not set

The First Hospital of Jilin University, Changchun City, Not set

West China Hospital of Sichuan University, Chengdu City, Not set

Chongqing Cancer Hospital, Chongqing, Not set

Fujian Provincial Cancer Hospital, Fuzhou City, Not set

Sun yat-sen University Cancer Center, Guangzhou, Not set

Guangxi Cancer Hospital of Guangxi Medical University, Nanning City, Not set

Fudan University Shanghai Cancer Center, Shanghai, Not set

The First Affiliated Hospital of China Medical University, Shenyang City, Not set

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou City, Not set

Henan Cancer Hospital, Zhengzhou City, Not set

The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Not set

Hopital Claude Huriez, Lille, Not set

Hopital Saint Eloi, Montpellier, Not set

CHU NANTES - Hôtel Dieu, Nantes, Not set

INSTITUT CURIE_SITE PARIS - Service d'Oncologie Médicale., Paris, Not set

Hopital Necker, Paris, Not set

Policlinico S.Orsola-Malpighi, Bologna, Emilia-Romagna

Humanitas Gavazzeni, Bergamo, Lombardia

Irccs Istituto Europeo Di Oncologia (IEO), Milano, Lombardia

SC Ematologia, AO SS. Antonio e Biagio e C. Arrigo, Alessandria, Piemonte

A.O. Città della Salute e della Scienza D - Osp. S. Giov. Battista Molinette, Torino, Piemonte

Chungnam National University Hospital, Daejeon, Not set

Severance Hospital, Yonsei University Health System, Seoul, Not set

Seoul National University Hospital, Seoul, Not set

Asan Medical Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Auxilio Mutuo Cancer Center, San Juan, Not set

Hospital Universitario Puerta del Mar, Cádiz, Cadiz

Hospital Universitari Vall d'Hebron, Barcelona, Not set

Hospital Clinic de Barcelona, Barcelona, Not set

Complejo Hospitalario Universitario A Coruña (CHUAC), La Coruna, Not set

Hospital General Universitario J.M Morales Meseguer, Murcia, Not set

Skånes University Hospital, Skånes Department of Onclology, Lund, Not set

Akademiska sjukhuset, Onkologkliniken, Uppsala, Not set

National Taiwan Universtiy Hospital, Taipei, Not set

Chang Gung Medical Foundation - Linkou, Taoyuan, Not set

NHS Greater Glasgow and Clyde, Glasgow, Not set

Lincolnshire County Hospital, Lincoln, Not set

University College London Hospital, London, Not set

Christie Hospital Nhs Trust, Manchester, Not set

Oxford Churchill Hospital, Oxford, Not set

Derriford Hospital, Plymouth, Not set

Conditions: Lymphoma

Learn More ›

A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

NCT04929223

Recruiting

This open-label, exploratory study is designed to evaluate the safety and efficacy of targeted therapies or immunotherapy as single agents or combinations, in participants with metastatic colorectal cancer (mCRC) whose tumors are biomarker positive as per treatment arm-specific definition. Eligible participants with mCRC will be enrolled into specific treatment arms based on their biomarker assay results.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/01/2025

Locations: UAB Comprehensive Cancer Center, Birmingham, Alabama +72 locations

UAB Comprehensive Cancer Center, Birmingham, Alabama

Mayo Clinic Arizona, Phoenix, Arizona

City of Hope Comprehensive Cancer Center, Duarte, California

cCare, Encinitas, California

USC Norris Cancer Center, Los Angeles, California

Cedars-Sinai Medical Center, Los Angeles, California

UCLA, Los Angeles, California

Hoag Memorial Hospital Presbyterian, Newport Beach, California

Stanford Cancer Center, Stanford, California

University of Colorado Cancer Center, Aurora, Colorado

Yale Cancer Center, New Haven, Connecticut

Eastern Ct Hema/Onco Assoc, Norwich, Connecticut

Mayo Clinic in Florida, Jacksonville, Florida

Moffitt Cancer Center, Tampa, Florida

Mary Bird Perkins Cancer Ctr, Baton Rouge, Louisiana

Massachusetts General Hospital, Boston, Massachusetts

Karmanos Cancer Institute, Detroit, Michigan

Mayo Clinic Rochester, Rochester, Minnesota

New York Cancer & Blood Specialists - Bronx, Bronx, New York

New York Cancer & Blood Specialists - New Hyde Park, New Hyde Park, New York

New York Cancer and Blood Specialists-Central Park Hematology & Oncology, New York, New York

New York Cancer & Blood Specialists, Port Jefferson Station, New York

Duke University Medical Center, Durham, North Carolina

Hematology Oncology Salem, Salem, Oregon

UPMC - Hillman Cancer Center, Pittsburgh, Pennsylvania

Sarah Cannon Research Institute / Tennessee Oncology, Nashville, Tennessee

Vanderbilt University Medical Center, Nashville, Tennessee

Lumi Research, Kingwood, Texas

Swedish Cancer Inst., Seattle, Washington

Medical Oncology Associates, Spokane, Washington

Peter Maccallum Cancer Centre, Melbourne, Victoria

Princess Margaret Cancer Center, Toronto, Ontario

Jewish General Hospital, Montreal, Quebec

McGill University Health Center, Montreal, Quebec

Rigshospitalet, Onkologisk Klinik, København Ø, Not set

Charité Universitätsmedizin Berlin, Berlin, Not set

Katholisches Klinikum Bochum gGmbH - St. Josef-Hospital, Bochum, Not set

Universitätsklinik Carl Gustav Carus der Technischen Universität Dresden, Dresden, Not set

Universitätsklinikum Düsseldorf, Düsseldorf, Not set

Asklepios Klinik Altona, Hamburg, Not set

SLK-Kliniken Heilbronn GmbH;Klinik für Innere Medizin III, Heilbronn, Not set

Klinikum der Universität München, Campus Großhadern, München, Not set

Universitätsklinikum Ulm, Ulm, Not set

Università degli Studi della Campania Luigi Vanvitelli, Napoli, Campania

Policlinico Universitario Agostino Gemelli IRCCS, Roma, Lazio

Irccs Istituto Nazionale Dei Tumori (Int), Milano, Lombardia

Azienda Socio Sanitaria Territoriale Niguarda (Ospedale Niguarda Ca' Granda), Milano, Lombardia

IRCCS Istituto Oncologico Veneto (IOV), Padova, Veneto

National Cancer Center, Goyang-si, Not set

Chonnam National University Hwasun Hospital, Jeollanam-do, Not set

Seoul National University Bundang Hospital, Seongnam-si, Not set

Samsung Medical Center, Seoul, Not set

Seoul National University Hospital, Seoul, Not set

Severance Hospital, Yonsei University Health System, Seoul, Not set

Asan Medical Center, Seoul, Not set

Szpital Uniwersytecki w Krakowie, Oddzia? Kliniczny Kliniki Onkologii, Kraków, Not set

Uniwersytecki Szpital Kliniczny w Poznaniu, Poznan, Not set

Narodowy Instytut Onkologii im. M. Sklodowskiej-Curie, Warszawa, Not set

Vall d?Hebron Institute of Oncology (VHIO), Barcelona, Barcelona, Not set

START Madrid-FJD, Hospital Fundacion Jimenez Diaz, Madrid, Not set

START Madrid. Centro Integral Oncologico Clara Campal, Madrid, Not set

Hospital Clínico Universitario de Valencia, Valencia, Not set

National Cheng Kung University Hospital, Tainan, Not set

Taipei Veterans General Hospital, Taipei City, Not set

National Taiwan University Hospital, Zhongzheng Dist., Not set

Addenbrookes Hospital, Cambridge, Not set

Velindre Cancer Centre, Cardiff, Not set

Royal Free Hospital, London, Not set

Royal Marsden Hospital;Dept of Med-Onc, London, Not set

Sarah Cannon Research Institute, London, Not set

Imperial College Healthcare NHS Trust, London, Not set

The Christie NHS Foundation Trust, Manchester, Not set

Royal Marsden Hospital, Sutton, Not set

Conditions: Metastatic Colorectal Cancer

Learn More ›

A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria

NCT05196035

Recruiting

Researchers are looking for a better way to treat children who have chronic kidney disease (CKD), which is long-term kidney disease, and proteinuria, a condition in which a person´s kidneys leak protein into the urine. The kidneys filter waste and fluid from the blood to form urine. In children with CKD, the kidney´s filters do not work as well as they should. This can lead to accumulation of waste and fluid in the body and proteinuria. CKD can lead to other medical problems, such as high blood pressure, also known as hypertension. Vice versa, hypertension and proteinuria can also contribute to worsening of CKD. Therefore, the treatment of CKD aims to control blood pressure and proteinuria. There are treatments available for doctors to prescribe to children with CKD and hypertension and/or proteinuria. These include "angiotensin-converting enzyme inhibitors" (ACEI) and "angiotensin receptor blockers" (ARB). Both ACEI and ARB can improve kidney function by helping the renin-angiotensin-aldosterone system (RAAS) to work normally. The RAAS is a system that works with the kidneys to control blood pressure and the balance of fluid and electrolytes in the blood. In people with CKD, the RAAS is often too active, which can stop the kidneys from working properly and cause hypertension and proteinuria. However, ACEI or ARB treatment alone does not work for all patients with CKD as they only target the angiotensin part of the renin-angiotensin-aldosterone system. The study treatment, finerenone, is expected to help control RAAS overactivation together with an ACEI or ARB. So, the researchers in this study want to learn more about whether finerenone given in addition to either an ACEI or ARB can help their kidney function. The main purpose of this study is to learn more about whether finerenone added to either ACEI or ARB can help reduce the amount of protein in the participants' urine more than a placebo. A placebo looks like a treatment but does not have any medicine in it. Participants will also continue to receive their other medications. To see how the treatment work, the doctors will take samples of the participants' urine to measure their protein levels before and during taking treatment and after their last treatment. In addition, blood samples will be taken to monitor kidney function, electrolytes and the amount of finerenone in the blood as well as for other tests. This study will include children with CKD and proteinuria aged from 6 months up to less than 18 years. The participants will take: * either finerenone or the placebo, in addition to * either ACEI or ARB, whichever they take as part of their normal treatment Two visits are required up to 104 days, to check whether a child can take part in the treatment phase of the study. If participants qualify for the treatment phase, they will then undergo treatment for about 180 days. During this time, they will visit the study site at least 7 times. During these visits, the participants will: * have their blood pressure, heart rate, temperature, height and weight measured * have blood and urine samples taken * have physical examinations * have their heart examined by an electrocardiogram and echocardiography (a sonogram of the heart) * answer questions about their medication and whether they have any adverse events , or have their parents or guardians answer * answer questions about how they are feeling, or have their parents or guardians answer * answer question about how they like the study medication, or have their parents or guardians answer The doctors will keep track of any adverse events. An adverse event is any medical problem that a participant has during a study. Doctors keep track of all adverse events that happen in studies, even if they do not think the adverse events might be related to the study treatments. The doctors will check the participants' health about 30 days after the participants take their last treatment. Read Less

Gender:

ALL

Ages:

Between 6 months and 17 years

Trial Updated:

08/01/2025

Locations: Phoenix Children's Hospital | Main - Transplant Department, Phoenix, Arizona +153 locations

Phoenix Children's Hospital | Main - Transplant Department, Phoenix, Arizona

Cedars-Sinai Medical Center - Nephrology, Los Angeles, California

Lucille Packard Children's Hospital Stanford - Pediatric Nephrology, Palo Alto, California

Rady Children's Hospital San Diego - Cardiology, San Diego, California

Children's National Medical Center - Nephrology, Washington, District of Columbia

Memorial Transplant Institute - Pediatric Nephrology, Hollywood, Florida

Emory University Hospital/Children's Healthcare of Atlanta - Nephrology, Atlanta, Georgia

University of Iowa Health Care Medical Center - Nephrology, Iowa City, Iowa

The Charlotte R. Bloomberg Children's Center Building - Nephrology, Baltimore, Maryland

Boston Children's Hospital - Main Campus - Nephrology, Boston, Massachusetts

Children's Mercy Hospital Kansas City - Nephrology, Kansas City, Missouri

Cincinnati Children's Hospital Medical Center | Division of Nephrology and Hypertension, Cincinnati, Ohio

Cleveland Clinic | Pediatric Nephrology, Cleveland, Ohio

OHSU Doernbecher Children's Hospital - Neurology, Portland, Oregon

Children's Hospital of Philadelphia - Nephrology, Philadelphia, Pennsylvania

Univ of Texas Health Science Center | Nephrology Res Dept, San Antonio, Texas

Primary Children's Hospital, Salt Lake City, Utah

Seattle Children's Hospital - Nephrology, Seattle, Washington

Instituto Universitario Hospital Italiano de Buenos Aires | Hospital Italiano de Buenos Aires - Neurology Department, Ciudad Autonoma de Buenos Aire, Ciudad Auton. De Buenos Aires

Hospital General de Ninos Ricardo Gutierrez | Pediatric Nephrology Department, Ciudad Autonoma de Buenos Aire, Ciudad Auton. De Buenos Aires

Centro de Rehabilitacion Cardiovascular | San Luis, Argentina, San Luis, Provincia De San Luis

Clinica de Nefrologia, Urologia y Enfermedades Cardiovascualares | Santa Fe, Argentina, Santa Fe, Provincia De Santa Fe

Hospital de Pediatría Juan P. Garrahan, Buenos Aires, Not set

Hospital General de Ninos Pedro de Elizalde | Nephrology Department, Buenos Aires, Not set

Queensland Children's Hospital, South Brisbane, Queensland

Monash Children's Hospital, Clayton, Victoria

Royal Children's Hospital Melbourne, Parkville, Victoria

Kepler Universitätsklinikum Campus IV, Linz, Oberösterreich

Medizinische Univ Graz | Kinder & Jugendheilkunde, Graz, Steiermark

Uniklinikum Salzburg - Landeskrankenhaus, Salzburg, Not set

AKH Wien | Kinder & Jugendheilkunde, Kindernephrologie, Wien, Not set

Huderf / Ukzkf, Bruxelles - Brussel, Not set

CU Saint-Luc/UZ St-Luc, Bruxelles - Brussel, Not set

UZ Gent, Gent, Not set

UZ Gasthuisberg - Pediatric Nephrology, Leuven, Not set

CHC Montlégia - Pediatrics, Liège, Not set

Santa Casa de Misericórdia de Belo Horizonte, Belo Horizonte, Minas Gerais

Hospital Pequeno Principe, Curitiba, Parana

Hosp Clínicas Facult. Med. de Ribeirão Preto / USP, Ribeirão Preto/SP, Sao Paulo

Hospital PUC-Campinas | Centro de Pesquisa Clínica Sao Lucas, São Paulo, Sao Paulo

Hospital Infantil Sabará - Instituto PENSI - Pesquisa e Ensino em Saúde Infantil, Sao Paulo, SP

Instituto da Crianca e do Adolescente, Sao Paulo, Not set

UMHAT Sveti Georgi, Plovdiv, Not set

SHATPD "Prof. Ivan Mitev", Sofia, Not set

MHAT prof. Stoyan Kirkovitch AD, Stara Zagora, Not set

Alberta Children's Hospital - Nephrology Clinic, Calgary, Alberta

McMaster Children's Hospital, Hamilton, Ontario

CHU Sainte-Justine, Montreal, Quebec

Všeobecná fakultní nemocnice v Praze, Praha 2, Not set

Fakultní nemocnice v Motole, Praha 5, Not set

Rigshospitalet - Børn og Unge, Copenhagen, Not set

Odense Universitetshospital - HC Andersen Børne og Ungehospital, Odense C, Not set

Aarhus Universitetshospital - Børn og Unge, Århus N, Not set

Helsinki University Hospital | Children's Hospital - Clinical Trial Unit, Nephrology Department, Helsinki, Not set

Tays Service Centre | Tampere University Hospital - Pediatric Early Phase Clinical Trials Unit, Tampere, Not set

Turun yliopistollinen keskussairaala, Turku, Not set

CHU bordeaux - Hopital Pellegrin, BORDEAUX cedex, Not set

CHU de Lyon - Hopital Femme Mère Enfant, Bron, Not set

Hopital Arnaud de Villeneuve CHU Montpellier, Montpellier, Not set

Hopital Robert Debre, Paris, Not set

CHU Strasbourg - Hopital Hautepierre, Strasbourg, Not set

Hôpital des Enfants, TOULOUSE Cedex 9, Not set

Universitätsklinikum Heidelberg, Heidelberg, Baden-Württemberg

Universitätsklinikum Erlangen, Erlangen, Bayern

Medizinische Hochschule Hannover (MHH), Hannover, Niedersachsen

Kindernierenzentrum Bonn, Bonn, Nordrhein-Westfalen

Universitätsklinikum Essen, Essen, Nordrhein-Westfalen

Universitaetsklinikum Muenster, Münster, Nordrhein-Westfalen

Charité / Pädiatrie, Berlin, Not set

Universitätsklinikum Hamburg Eppendorf (UKE), Hamburg, Not set

Children's Hospital of Athens P&A Kyriakou - Pediatric Nephrology Department, Athens, Not set

Children's Hospital of Athens Agia Sofia - Pediatric Nephrology Department, Athens, Not set

University General Hospital of Heraklion - Department of Paediatrics, Heraklion, Not set

Univ. General Hospital of Ioannina - Department of Paediatrics, Nephrology Unit, Ioannina, Not set

Hippokration General Hospital of Thessaloniki - 3rd Department of Paediatrics, Nephrology Unit', Thessaloniki, Not set

Semmelweis University, Budapest, Not set

Debreceni Egyetem Klinikai Kozpont, Debrecen, Not set

Pecsi Tudomanyegyetem Klinikai Kozpont, Pecs, Not set

SZTE ÁOK Szent Györgyi Albert Klinikai Kozpont, Szeged, Not set

Institute of Kidney Diseases and Research Center Gujarat University of Transplantation Sciences, Ahmedabad, Not set

St. John's National Academy of Health Sciences, Bangalore, Not set

Post Graduate Institute of Medical Education and Research, Chandigarh, Not set

All India Institute of Medical Sciences (AIIMS) - New Delhi, Delhi, Not set

NRS Medical college, Kolkata, Not set

Clalit Health | Soroka Medical Center - Internal Medicine Department, Beer Sheva, Not set

Wilf Children's Hospital Shaare Zedek Medical Center, Jerusalem, Not set

Health Corporation of Galilee Medical Center, Nahariya, Not set

Clalit Health Services Schneider Children's Medical Center, Petach Tikva, Not set

Dana-Dwek Children's Hospital, Tel Aviv, Not set

Azienda Ospedaliero-Universitaria Di Bologna IRCCS_Policlinico Sant'Orsola - Pediatria, Bologna, Emilia-Romagna

Ospedale Pediatrico Bambino Gesù - Nefrologia, Roma, Lazio

IRCCS Istituto Giannina Gaslini - Nefrologia e Trapianto Rene, Genova, Liguria

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico - Nefrologia e Dialisi Pediatrica, Trapianti di Rene, Milano, Lombardia

Azienda Ospedaliera Universitaria Meyer IRCCS - Nefrologia e Dialisi, Firenze, Not set

A.O.U. Città della Salute e della Scienza di Torino_Regina Margherita - Nefrologia Pediatrica, Torino, Not set

Kyungpook National University Hospital, Daegu, Daegu Gwang''yeogsi

Seoul National University Bundang Hospital, Seongnam-si, Gyeonggido

Pusan National University Yangsan Hospital, Yangsan-si, Gyeongsangnamdo

Korea University Guro Hospital, Seoul, Seoul Teugbyeolsi

Seoul National University Hospital, Seoul, Seoul Teugbyeolsi

Hospital of LT University of Health Sciences Kaunas Clinics, Kaunas, Not set

Vilnius University Hospital Santaros Klinikos Children's Hospital Paediatrics Centre, Vilnius, Not set

Hospital Tunku Azizah, Wilayah Persekutuan, Kuala Lumpur

Hospital Tuanku Ja'afar, Seremban, Negeri Sembilan

Hospital Selayang, Shah Alam, Selangor

Sunway Medical Centre, Subang Jaya, Selangor

Hospital Universiti Sains Malaysia, Kelantan, Not set

Sitio Alfredo Chew Wong | Aguascalientes, Mexico, Aguascalientes, Agguascalientes

Instituto Veracruzano en Investigación Clinica SC, Ciudad de Mexico, Distrito Federal

Hospital Infantil de México "Dr. Federico Gómez", México D.F., Distrito Federal

Instituto Nacional de Pediatría, México, D.F., Distrito Federal

Hospital Regional de Alta Especialidad Ixtapaluca, Ixtapaluca, Estado De Mexico

Hospital Universitrio Dr. José Eleuterio González. Servicio de Oncologia, Nuevo León, Monterrey

Universitair Medisch Centrum Groningen, Groningen, Not set

University Medical Center Utrecht, Utrecht, Not set

Uniwersytecki Dzieciecy Szpital Kliniczny im. L. Zamenhofa, Bialystok, Not set

Uniwersyteckie Centrum Kliniczne, Gdansk, Not set

Uniwersytecki Szpital Dzieciecy w Krakowie, Krakow, Not set

Instytut Centrum Zdrowia Matki Polki, Lodz, Not set

Instytut "Pomnik - Centrum Zdrowia Dziecka", Warszawa, Not set

Uniwersytecki Szpital Kliniczny UM we Wroclawiu, Wroclaw, Not set

Hospital Pediátrico de Coimbra I ULS Coimbra, Coimbra, Not set

Centro Hospitalar Universitario do Porto | Servico de Investigacao Clinica, Porto, Not set

Wits Vaccines & Infectious Diseases Analytics (VIDA) Research Unit, Soweto, Gauteng

Ciutat Sanitaria i Universitaria de la Vall d'Hebron, Barcelona, Not set

Hospital de Sant Joan de Déu, Barcelona, Not set

H Univ. 12 de Octubre | Unidad Pediátrica Inv y EECC (UPIC), Madrid, Not set

Hospital la Paz, Madrid, Not set

Hospital Universitario Regional De Malaga - Nefrologia pediatrica, Málaga, Not set

Hospital Universitario Virgen Del Rocio S.L. - Nefrologia pediatrica, Sevilla, Not set

Skånes Universitetssjukhus Lund - Barnnefroenheten, Lund, Not set

Karolinska University Hospital, Stockholm, Not set

Uppsala University Hospital, Uppsala, Not set

Universitäts-Kinderspital UKBB, Basel, Basel-Stadt

Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Vaud

Hopital des Enfants HUG, Geneva, Not set

National Cheng Kung University Hospital, Tainan, TNN

Chang Gung Memorial Hospital (CGMH) - Kaohsiung Branch, Guishan, Not set

Kaohsiung Veterans General Hospital, Kaohsiung City, Not set

National Taiwan University Hospital, Taipei, Not set

Chang Gung Memorial Hospital at Linkou, Taipei, Not set

Taipei Veterans General Hospital, Taipei, Not set

Cukurova Univ. Tip. Fak. Balcali Hastanesi, Adana, Not set

Hacettepe Universitesi Tip Fakultesi, Ankara, Not set

Baskent Universitesi Tip Fakultesi Hastanesi, Ankara, Not set

Gazi Universitesi Tip Fakultesi, Ankara, Not set

Health Ministry Of Türkiye Republic Ankara Bilkent City Hospital, Ankara, Not set

Istanbul Faculty of Medicine, Department of Internal Medicine, Department of Pediatrics, Istanbul, Not set

Istanbul Universitesi Cerrahpasa - Cocuk Nefrolojisi, Istanbul, Not set

Marmara University Medical Faculty | Pediatric Nephrology, Istanbul, Not set

NHS Greater Glasgow and Clyde | Royal Hospital for Children - Glasgow Clinical Research Facility, Glasgow, Not set

Great Ormond Street Hospital for Children, London, Not set

Manchester University NHS Foundation Trust | Royal Manchester Children's Hospital - Clinical Research Facility, Manchester, Not set

Nottingham University Hospitals NHS Trust | Queens Medical Centre - Childrens Clinical Research Facility, Nottingham, Not set

Conditions: Chronic Kidney Disease, Proteinuria

Learn More ›

Study to Explore the Therapeutic Effect of Eluxadoline in Treating Irritable Bowel Syndrome With Diarrhea in Children

NCT03339128

Recruiting

The primary objectives of this study are to explore the therapeutic effect of eluxadoline in treating irritable bowel syndrome with diarrhea (IBS-D) in pediatric participants 6-17 years of age, to evaluate the pharmacokinetics of eluxadoline in pediatric participants with IBS-D, and to evaluate the safety and tolerability of eluxadoline in pediatric participants with IBS-D. Enrollment of 12-17 years old age group is closed, enrollment of the 6-11 years old age group will continue.

Gender:

ALL

Ages:

Between 6 years and 17 years

Trial Updated:

08/01/2025

Locations: HealthStar Research of Hot Springs PLLC /ID# 234609, Hot Springs, Arkansas +45 locations

HealthStar Research of Hot Springs PLLC /ID# 234609, Hot Springs, Arkansas

Applied Research Center of Arkansas /ID# 238070, Little Rock, Arkansas

Kindred Medical Institute, LLC /ID# 237368, Corona, California

Duplicate_VVCRD Research /ID# 234606, Garden Grove, California

Duplicate_Center for Clinical Trials LLC /ID# 234630, Paramount, California

Duplicate_Wellness Clinical Research /ID# 237401, Miami Lakes, Florida

Sunrise Research Institute /ID# 237382, Miami, Florida

South Miami Medical & Research Group Inc. /ID# 234655, Miami, Florida

Valencia Medical & Research Center /ID# 234672, Miami, Florida

Florida Research Center, Inc. /ID# 236514, Miami, Florida

Global Research Associates /ID# 234646, Atlanta, Georgia

Children's Ctr Digestive, US /ID# 237575, Atlanta, Georgia

Sleep Care Research Institute d/b/a Clinical Research Institute /ID# 236343, Stockbridge, Georgia

Advocate Children's Hospital-Park Ridge /ID# 235388, Park Ridge, Illinois

Indiana University Health Riley Hospital for Children /ID# 235400, Indianapolis, Indiana

Michael W. Simon, MD, PSC /ID# 236517, Lexington, Kentucky

Frederick County Pediatrics /ID# 234519, New Market, Maryland

MNGI Digestive Health, P. A. /ID# 238057, Minneapolis, Minnesota

Celen Medical Group Corp /ID# 234922, Marlton, New Jersey

IPS Research Company /ID# 237672, Oklahoma City, Oklahoma

Children's Hospital of Philadelphia - Main /ID# 234313, Philadelphia, Pennsylvania

Preferred Primary Care Physicians, Inc. /ID# 236436, Pittsburgh, Pennsylvania

Cook Children's Med. Center /ID# 237537, Fort Worth, Texas

Texas Children's Hospital /ID# 238304, Houston, Texas

Sun Research Institute /ID# 236933, San Antonio, Texas

West Virginia University Hospitals /ID# 256841, Morgantown, West Virginia

Medical center 1 Sevlievo /ID# 237473, Sevlievo, Gabrovo

MHATSv.Ivan Rilski /ID# 235399, Kozloduy, Not set

University Hospital Plovdiv /ID# 235450, Plovdiv, Not set

Duplicate_Edmonton Clinic Health Academy (ECHA) /ID# 234917, Edmonton, Not set

Manitoba Institute of Child Health /ID# 235448, Winnepeg, Not set

HELIOS Klinikum Wuppertal /ID# 237322, Wuppertal, Not set

Eszak-Kozep-budai Centrum, Uj Szent Janos Korhaz /ID# 236993, Budapest, Not set

Soproni Erzsebet Oktato Korhaz es Rehabilitacios Intezet /ID# 237341, Sopron, Not set

Vita Verum Medical Bt. /ID# 234321, Szekesfehervar, Not set

Duplicate_Academisch Medisch Centrum /ID# 237117, Amsterdam, Noord-Holland

Instytut Centrum Zdrowia Matki Polki /ID# 237438, Lodz, Lodzkie

Specjalistyczne Gabinety Sp. z o.o. /ID# 236347, Krakow, Malopolskie

Centrum Zdrowia MDM /ID# 237269, Warszawa, Mazowieckie

Duplicate_Instytut Pomnik - Centrum Zdrowia Dziecka /ID# 234311, Warszawa, Mazowieckie

Korczowski Bartosz Gabinet Lekarski /ID# 234683, Rzeszow, Podkarpackie

Copertnicus Podmiot Leczniczy Sp. z o.o. /ID# 235656, Gdansk, Pomorskie

Hospital Universitario Dr. Peset /ID# 236755, Valencia, Not set

Duplicate_Manchester University NHS Foundation Trust /ID# 234663, Manchester, Lancashire

Blackpool Teaching Hospitals NHS Foundation Trust /ID# 237273, Blackpool, Not set

King's College Hospital NHS Foundation Trust /ID# 236305, London, Not set

Conditions: Irritable Bowel Syndrome

Learn More ›

Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult Patients With Moderate to Severe Hidradenitis Suppurativa

NCT06840392

Recruiting

The purpose of this study is to establish the efficacy, safety, and tolerability of remibrutinib (LOU064) Dose A and Dose B compared to placebo in participants with moderate to severe hidradenitis suppurativa (HS).

Gender:

ALL

Ages:

Between 18 years and 100 years

Trial Updated:

08/01/2025

Locations: Total Skin and Beauty Dermatology Center PC, Birmingham, Alabama +96 locations

Total Skin and Beauty Dermatology Center PC, Birmingham, Alabama

CTT Research, Gilbert, Arizona

Ctr Dermatology and Plastic Surgery, Scottsdale, Arizona

Ctr for Dermatology Clinical Res, Fremont, California

USC Keck School of Medicine, Los Angeles, California

MedDerm Associates, San Diego, California

Driven Research, Coral Gables, Florida

Floridian Research Institute, Miami, Florida

Sarasota Arthritis Res Ctr, Sarasota, Florida

University Of South Florida, Tampa, Florida

Emory School of Med Dermatology, Atlanta, Georgia

Endeavor Health, Glenview, Illinois

Dundee Dermatology, West Dundee, Illinois

Southern IN Clinical Trials, New Albany, Indiana

Metro Boston Clinical Partners, Brighton, Massachusetts

Clinical Research Inst of MI, Chesterfield, Michigan

Skin Specialists PC, Omaha, Nebraska

Vivida Dermatology, Las Vegas, Nevada

North Shore University Hospital, New Hyde Park, New York

Cameron Dermatology, New York, New York

Optima Research Boardman, Boardman, Ohio

Ohio State University, Columbus, Ohio

Wright State University, Fairborn, Ohio

Apex Clinical Research Center LLC, Mayfield Heights, Ohio

Clinical Research Ctr of Carolinas, Charleston, South Carolina

Rivergate Dermatology and Skin Care Center, Goodlettsville, Tennessee

Accurate Clinical Research, Humble, Texas

Austin Inst for Clinical Research, Pflugerville, Texas

Center for Clinical Studies-Lee, Webster, Texas

Care Access Alexandria, Arlington, Virginia

Complexions Dermatology, Danville, Virginia

Forefront Dermatology, Vienna, Virginia

Novartis Investigative Site, Caba, Not set

Novartis Investigative Site, Linz, Not set

Novartis Investigative Site, Leuven, Not set

Novartis Investigative Site, Liege, Not set

Novartis Investigative Site, Edmonton, Alberta

Novartis Investigative Site, London, Ontario

Novartis Investigative Site, Montreal, Quebec

Novartis Investigative Site, Sherbrooke, Quebec

Novartis Investigative Site, Quebec, Not set

Novartis Investigative Site, Karlovy Vary, Czech Republic

Novartis Investigative Site, Prague 8, Czech Republic

Novartis Investigative Site, Plzen Bolevec, Not set

Novartis Investigative Site, Praha 10, Not set

Novartis Investigative Site, Praha 2, Not set

Novartis Investigative Site, Praha, Not set

Novartis Investigative Site, Brest, Not set

Novartis Investigative Site, La Rochelle, Not set

Novartis Investigative Site, Lyon, Not set

Novartis Investigative Site, Nice, Not set

Novartis Investigative Site, Reims, Not set

Novartis Investigative Site, Rouen, Not set

Novartis Investigative Site, Toulouse, Not set

Novartis Investigative Site, Merzig, Saarland

Novartis Investigative Site, Leipzig, Sachsen

Novartis Investigative Site, Bad Bentheim, Not set

Novartis Investigative Site, Dessau-Rosslau, Not set

Novartis Investigative Site, Dortmund, Not set

Novartis Investigative Site, Duesseldorf, Not set

Novartis Investigative Site, Essen, Not set

Novartis Investigative Site, Freiburg, Not set

Novartis Investigative Site, Hamburg, Not set

Novartis Investigative Site, Luebeck, Not set

Novartis Investigative Site, Minden, Not set

Novartis Investigative Site, Muenchen, Not set

Novartis Investigative Site, Tuebingen, Not set

Novartis Investigative Site, Wuerzburg, Not set

Novartis Investigative Site, Thessaloniki, GR

Novartis Investigative Site, Athens, Not set

Novartis Investigative Site, Budapest, Not set

Novartis Investigative Site, Debrecen, Not set

Novartis Investigative Site, Kecskemet, Not set

Novartis Investigative Site, Pecs, Not set

Novartis Investigative Site, Szeged, Not set

Novartis Investigative Site, Ipoh, Perak

Novartis Investigative Site, Kota Kinabalu, Sabah

Novartis Investigative Site, Kuala Lumpur, Wilayah Persekutuan

Novartis Investigative Site, Johor Bahru, Not set

Novartis Investigative Site, Selangor Darul Ehsan, Not set

Novartis Investigative Site, Wilayah Persekutuan, Not set

Novartis Investigative Site, Warsaw, Not set

Novartis Investigative Site, Warszawa, Not set

Alma Cruz-Santana Private Practice, Carolina, Not set

Novartis Investigative Site, Bucharest, District 2

Novartis Investigative Site, Sevilla, Andalucia

Novartis Investigative Site, Palma De Mallorca, Islas Baleares

Novartis Investigative Site, Granollers, Not set

Novartis Investigative Site, Las Palmas de Gran Canaria, Not set

Novartis Investigative Site, Madrid, Not set

Novartis Investigative Site, Pontevedra, Not set

Conditions: Hidradenitis Suppurativa

Learn More ›

Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

NCT06562192

Recruiting

The purpose of this study is to evaluate the safety, tolerability, dosimetry and preliminary efficacy of \[177Lu\]Lu-NNS309 and the safety and imaging properties of \[68Ga\]Ga-NNS309 in patients aged ≥ 18 years with locally advanced or metastatic pancreatic ductal adenocarcinoma (PDAC), non-small cell lung cancer (NSCLC), HR+/HER2- ductal and lobular breast cancer (BC), triple negative breast cancer (TNBC) and colorectal cancer (CRC).

Gender:

ALL

Ages:

Between 18 years and 100 years

Trial Updated:

08/01/2025

Locations: Stanford University Medical Center, Stanford, California +15 locations

Conditions: Pancreatic Ductal Adenocarcinoma, Non-small Cell Lung Cancer, HR+/HER2- Ductal and Lobular Breast Cancer, Triple Negative Breast Cancer, Colorectal Cancer

Learn More ›

A Study Evaluating Single-agent Inavolisib and Inavolisib Plus Atezolizumab in PIK3CA-Mutated Cancers

NCT06496568

Recruiting

The purpose of the study is to assess the safety and efficacy of inavolisib as a single-agent and in combination with atezolizumab in participants with phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PIK3CA)-mutated cancers, including previously treated head and neck squamous cell carcinoma (HNSCC).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/01/2025

Locations: Moores Cancer Center at UC San Diego Health, La Jolla, California +7 locations

Conditions: PIK3CA-Mutated Cancers

Learn More ›

Study to Assess Adverse Events, Change in Disease Activity, and How Oral Upadacitinib Moves Through the Body of Pediatric Participants With Moderately to Severely Active Ulcerative Colitis.

NCT05782907

Recruiting

Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large intestine). This study will assess how safe and effective Upadacitinib is in treating pediatric participants with UC. Adverse events and change in disease activity will be assessed. Upadacitinib (RINVOQ) is a drug approved in adults for moderate- to severely active UC and is being developed for moderate- to severely active UC in pediatric participa... Read More

Gender:

ALL

Ages:

Between 2 years and 17 years

Trial Updated:

08/01/2025

Locations: Phoenix Children's Hospital /ID# 250135, Phoenix, Arizona +87 locations

Phoenix Children's Hospital /ID# 250135, Phoenix, Arizona

Arkansas Children's Hospital /ID# 250106, Little Rock, Arkansas

Kindred Medical Institute - Corona /ID# 255484, Corona, California

UCSF Benioff Children's Hospital - Oakland /ID# 255067, Oakland, California

Lucile Packard Children's Hospital /ID# 258430, Palo Alto, California

Children's Hospital Colorado - Aurora /ID# 250110, Aurora, Colorado

Nemours/Alfred duPont Hospital for Children /ID# 255483, Wilmington, Delaware

Childrens Healthcare of Atlanta - Center for Advanced Pediatrics /ID# 255069, Atlanta, Georgia

Ann & Robert H Lurie Children's Hospital of Chicago /ID# 254505, Chicago, Illinois

OSF St. Francis Medical Center /ID# 256968, Peoria, Illinois

Massachusetts General Hospital /ID# 250142, Boston, Massachusetts

Boston Children's Hospital /ID# 250108, Boston, Massachusetts

NYU Langone Hospital - Long Island /ID# 250136, Mineola, New York

The Mount Sinai Hospital /ID# 250141, New York, New York

Univ NC Chapel Hill /ID# 254541, Chapel Hill, North Carolina

Levine Children's Hospital /ID# 250131, Charlotte, North Carolina

UH Cleveland Medical Center /ID# 250134, Cleveland, Ohio

Children's Hospital of Philadelphia - Main /ID# 258773, Philadelphia, Pennsylvania

Children's Specialty Group /ID# 256966, Norfolk, Virginia

University of Wisconsin - Madison /ID# 250632, Madison, Wisconsin

Children's Hospital at Westmead /ID# 255556, Westmead, New South Wales

Queensland Children's Hospital /ID# 261032, South Brisbane, Queensland

Monash Health - Monash Medical Centre /ID# 254726, Clayton, Victoria

Perth Children'S Hospital /ID# 254727, Perth, Western Australia

Universitair Ziekenhuis Antwerpen /ID# 251184, Edegem, Antwerpen

Universitair Ziekenhuis Leuven /ID# 251185, Leuven, Vlaams-Brabant

Hospital Pequeno Príncipe /ID# 251911, Curitiba, Parana

Hospital e Maternidade Celso Pierro - PUC-Campinas /ID# 251912, Campinas, Sao Paulo

Rocco & Nazato Servicos Medicos /ID# 251910, São Paulo, Sao Paulo

UMHAT Sveti Georgi /ID# 251949, Plovdiv, Not set

Specialized Hospital For Active Treatment Of Children Diseases Prof. Ivan Mitev /ID# 251285, Sofiya, Not set

UMHAT Multiprofile Hospital for Active Treatment Sveta Marina /ID# 251948, Varna, Not set

Alberta Health Services /ID# 252088, Edmonton, Alberta

BC Children's Hospital /ID# 250947, Vancouver, British Columbia

IWK Health Center /ID# 250943, Halifax, Nova Scotia

Hospital for Sick Children /ID# 250945, Toronto, Ontario

Fakultní Nemocnice Plzeň-Lochotín /ID# 253284, Pilsen, Plzen-jih

Fakultní nemocnice v Motole /ID# 251955, Prague, Praha 5

CHU Bordeaux - Hopital Pellegrin /ID# 253182, Bordeaux, Nouvelle-Aquitaine

Hospices Civils de Lyon - Hôpital Femme Mère Enfant /ID# 251502, Bron CEDEX, Rhone

AP-HP - Hopital Necker /ID# 251658, Paris, Not set

Hopitaux de Paris (AP-HP) - Hopital Robert Debre - CHU /ID# 252069, Paris, Not set

CHU Toulouse - Hopital Paule de Viguier /ID# 252070, Toulouse, Not set

Dr. von Haunerschen Kinderspital /ID# 251440, Muenchen, Bayern

Universitaetsklinikum Muenster /ID# 256763, Muenster, Nordrhein-Westfalen

Klinikum St. Georg gGmbH /ID# 262481, Leipzig, Sachsen

Charite Universitaetsmedizin Berlin Campus Virchow-Klinikum /ID# 251434, Berlin, Not set

Agia Sofia Hospital /ID# 250697, Athens, Attiki

University General Hospital of Heraklion PA.G.N.I /ID# 250696, Heraklion, Kriti

Debreceni Egyetem-Klinikai Kozpont /ID# 251835, Debrecen, Hajdu-Bihar

Semmelweis Egyetem /ID# 251083, Budapest, Not set

Schneider Children's Medical Center /ID# 254833, Petah Tikva, HaMerkaz

Shaare Zedek Medical Center /ID# 254832, Jerusalem, Yerushalayim

Azienda Ospedaliero Universitaria Meyer /ID# 251624, Florence, Firenze

Azienda Ospedaliero-Universitaria Policlinico Umberto I /ID# 251625, Rome, Roma

Ospedale Maggiore Carlo Alberto Pizzardi /ID# 251626, Bologna, Not set

Tsujinaka Hospital Kashiwanoha /ID# 251930, Kashiwa-shi, Chiba

Kurume University Hospital /ID# 251927, Kurume-shi, Fukuoka

Hokkaido P.W.F.A.C. Sapporo-Kosei General Hospital /ID# 251928, Sapporo-shi, Hokkaido

Miyagi Children's Hospital /ID# 251931, Sendai-shi, Miyagi

Osaka Women's and Children's Hospital /ID# 252397, Izumi-Shi, Osaka

Osaka General Medical Center /ID# 253678, Osaka-shi, Osaka

Saitama Children's Medical Center /ID# 252362, Saitama-shi, Saitama

Institute of Science Tokyo Hospital /ID# 251929, Bunkyo-ku, Tokyo

Tokyo Metropolitan Children's Medical Center /ID# 252477, Fuchu-shi, Tokyo

National Center for Child Health and Development /ID# 251926, Setagaya-ku, Tokyo

Seoul National University Hospital /ID# 252024, Seoul, Seoul Teugbyeolsi

Samsung Medical Center /ID# 252023, Seoul, Seoul Teugbyeolsi

Kyungpook National University Chilgok Hospital /ID# 252663, Daegu, Not set

Servicios de Oncologia Medica Integral SA de CV /ID# 252974, San Pedro Garza Garcia, Nuevo Leon

Amsterdam UMC, locatie AMC /ID# 250845, Amsterdam, Noord-Holland

Universitair Medisch Centrum Groningen /ID# 252003, Groningen, Not set

Christchurch Hospital. /ID# 254703, Christchurch, Canterbury

Starship Child Health /ID# 254702, Auckland, Not set

Gastromed Sp. z o.o /ID# 251290, Torun, Kujawsko-pomorskie

Instytut Pomnik - Centrum Zdrowia Dziecka /ID# 251289, Warsaw, Mazowieckie

Clinical Research Puerto Rico /ID# 266477, San Juan, Not set

Hospital Arquitecto Marcide - Complejo Hospitalario Universitario de Ferrol /ID# 252105, Ferrol, A Coruna

Hospital Sant Joan de Deu /ID# 251194, Esplugues de Llobregat, Barcelona

Hospital Universitario Vall d'Hebron /ID# 252104, Barcelona, Not set

Hospital Regional Universitario de Malaga /ID# 251193, Malaga, Not set

National Taiwan University Hospital /ID# 251650, Taipei City, Taipei

Linkou Chang Gung Memorial Hospital /ID# 251654, Taoyuan City, Not set

Sheffield Children's Hospital NHS Foundation Trust /ID# 251600, Sheffield, England

Disc_Barts Health NHS Trust - The Royal London Hospital /ID# 251917, London, Greater London

Great Ormond Street Children's Hospital /ID# 252126, London, Greater London

University Hospital Southampton NHS Foundation Trust /ID# 252097, Southampton, Hampshire

Birmingham Women's and Children's NHS Foundation Trust /ID# 253072, Birmingham, Not set

Conditions: Ulcerative Colitis

Learn More ›

A Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Previously Treated KRAS G12C-positive Advanced or Metastatic Non-Small Cell Lung Cancer

NCT06497556

Recruiting

The purpose of this study is to assess the safety and efficacy of divarasib compared to locally approved KRAS G12C inhibitors (sotorasib or adagrasib) in participants with KRAS G12C-positive (KRAS G12C +) advanced or metastatic non-small cell lung cancer (NSCLC).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/01/2025

Locations: Banner Health MD Anderson AZ, Gilbert, Arizona +251 locations

Banner Health MD Anderson AZ, Gilbert, Arizona

Banner Health MD Anderson AZ, Phoenix, Arizona

University of Arkansas For Medical Sciences, Little Rock, Arkansas

Los Angeles Cancer Network, Los Angeles, California

UCLA Hematology / Oncology Clinic, Los Angeles, California

Community Clinical Trials, Orange, California

Zuckerberg San Francisco General Hospital, San Francisco, California

University of California, San Francisco, San Francisco, California

UC Health Oncology Research, Colorado Springs, Colorado

Yale Cancer Center, New Haven, Connecticut

Bay Pines Foundation Inc, Bay Pines, Florida

Florida Cancer Specialists, Fort Myers, Florida

University of Miami, Miami, Florida

Cancer Specialists of North Florida, Saint Augustine, Florida

Florida Cancer Specialists., Saint Petersburg, Florida

Florida Cancer Specialists, West Palm Beach, Florida

University Cancer & Blood Center, LLC, Athens, Georgia

Summit Cancer Care PC, Savannah, Georgia

Rush University Medical Center, Chicago, Illinois

University of Chicago Medical Center, Chicago, Illinois

IU Health Ball Memorial Hospital, Muncie, Indiana

Mission Cancer + Blood - IMMC, Waukee, Iowa

Baptist Health Lexington, Lexington, Kentucky

Norton Cancer Institute- Poplar, Louisville, Kentucky

VA Shreveport Healthcare System, Shreveport, Louisiana

New England Cancer Specialists, Scarborough, Maine

Beth Israel Deaconess Medical Center, Boston, Massachusetts

Dana Farber Cancer Institute, Boston, Massachusetts

Dana Farber/Harvard Cancer Center (Foxborough), Foxboro, Massachusetts

Dana-Farber Cancer Institute, Methuen, Massachusetts

University of Michigan, Ann Arbor, Michigan

Henry Ford Health System;Clinical Trials Office, Detroit, Michigan

Cancer and Hematology Centers of Western Michigan, Grand Rapids, Michigan

Nebraska Methodist Estabrook Cancer Center, Omaha, Nebraska

Renown Regional Medical Center Hospital, Reno, Nevada

New York Cancer & Blood Specialists, Bronx, New York

New York Cancer & Blood Specialists - New Hyde Park, New Hyde Park, New York

New York Cancer and Blood Specialists-Central Park Hematology & Oncology, New York, New York

Mount SInai Medical Center, New York, New York

Columbia University Medical Center, New York, New York

North Shore Hematology Oncology Associates P.C. DBA New York Cancer and Blood Specialists, Shirley, New York

University of North Carolina At Chapel Hill, Chapel Hill, North Carolina

East Carolina University, Greenville, North Carolina

Firsthealth of The Carolinas, Pinehurst, North Carolina

Ohio State University Comprehensive Cancer Center, Columbus, Ohio

SCRI Mark H. Zangmeister Center, Columbus, Ohio

Taylor Cancer Research Center, Maumee, Ohio

Oncology Associates of Oregon, P.C, Eugene, Oregon

Oregon Health & Science University, Portland, Oregon

Fox Chase Cancer Center, Philadelphia, Pennsylvania

Allegheny Cancer Center, Pittsburgh, Pennsylvania

Gibbs Cancer Center & Research Institute, Spartanburg, South Carolina

Avera Cancer Institute, Sioux Falls, South Dakota

Tennessee Oncology, PLLC - Chattanooga, Chattanooga, Tennessee

Baptist Clinical Research Institute, Memphis, Tennessee

Tennessee Oncology, Nashville, Tennessee

JPS Health Network, Fort Worth, Texas

MD Anderson Cancer Center, Houston, Texas

Texas Oncology - Northeast Texas, Longview, Texas

Virginia Commonwealth University - Massey Cancer Center, Richmond, Virginia

Hospital Britanico, Buenos Aires, Not set

Centro Oncologico Korben, Ciudad Autonoma Buenos Aires, Not set

Clinica Adventista Belgrano, Ciudad Autonoma Buenos Aires, Not set

Sanatorio Parque S.A., Rosario, Not set

Kinghorn Cancer Centre, Darlinghurst, New South Wales

Liverpool Hospital, Liverpool, New South Wales

GenesisCare North Shore, St Leonards, New South Wales

Sunshine Coast University Hospital, Birtinya, Queensland

Lyell McEwin Hospital, Elizabeth Vale, South Australia

Peter Maccallum Cancer Centre, Melbourne, Victoria

Klinik Penzing, Wien, Not set

Institut für Lungenforschung Wien, Wien, Not set

Krankenhaus Nord - Klinik Floridsdorf, Wien, Not set

AZORG Campus Aalst-Moorselbaan, Aalst, Not set

UZ Brussel, Brussel, Not set

Cliniques Universitaires St-Luc, Bruxelles, Not set

UZ Antwerpen, Edegem, Not set

Jessa Zkh (Campus Virga Jesse), Hasselt, Not set

CHU de Liège (Sart Tilman), Liège, Not set

CHU UCL Mont-Godinne, Mont-godinne, Not set

AZ Delta (Campus Rumbeke), Roeselare, Not set

Vitaz, Sint Niklaas, Not set

ZAS Sint Augustinus Wilrijk, Wilrijk, Not set

Hospital Sao Rafael - HSR, Salvador, Bahia

Hospital Brasilia, Brasilia, Distrito Federal

Clinica Onconeo, Campo Grande, Mato Grosso Do Sul

Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Rio Grande Do Sul

Hospital Nossa Senhora da Conceicao, Porto Alegre, Rio Grande Do Sul

Hospital Mae de Deus, Porto Alegre, Rio Grande Do Sul

Hospital de Cancer de Barretos, Barretos, São Paulo

Hospital de Base de Sao Jose do Rio Preto, Sao Jose do Rio Preto, São Paulo

Hospital Sírio-Libanês, Sao Paulo, São Paulo

Hospital Alemao Oswaldo Cruz, Sao Paulo, São Paulo

Oncoclinicas Rio de Janeiro S.A., Rio de Janeiro, Not set

William Osler Health Centre - Brampton Civic Hospital, Brampton, Ontario

Princess Margaret Cancer Center, Toronto, Ontario

Jewish General Hospital, Montreal, Quebec

Aarhus Universitetshospital, Aarhus N, Not set

Herlev Hospital, Herlev, Not set

Regionshospitalet Gødstrup, Herning, Not set

Helsinki University Central Hospital, Helsinki, Not set

Kuopio Uni Hospital, Kuopio, Not set

Turku Uni Central Hospital, Turku, Not set

CHU Angers, Angers, Not set

CHRU Brest, Brest, Not set

Chu Toulouse, Bron, Not set

Hopital Louis Pradel, Bron, Not set

CHRU Lille, Lille, Not set

Centre Leon Berard, Lyon, Not set

CHU Montpellier, Montpellier, Not set

Centre Antoine Lacassagne Centre Régional de Lutte Contre Le Cancer, Nice, Not set

Hopital Tenon, Paris, Not set

CHU Bordeaux, Pessac, Not set

CH de Saint Quentin, Saint Quentin, Not set

Chru de Strasbourg, Strasbourg, Not set

Hia Sainte Anne, Toulon, Not set

Evangelische Lungenklinik Berlin, Berlin, Not set

Charité Universitätsmedizin Berlin, Med Klinik Infekto und Pneumo, Berlin, Not set

Helios Klinikum Emil von Behring GmbH, Berlin, Not set

Klinikum Braunschweig, Braunschweig, Not set

KEM/Evang. Kliniken Essen Mitte gGmbH, Essen, Not set

Universitätsklinikum Essen, Essen, Not set

Klinikum Esslingen, Esslingen, Not set

Asklepios Fachkliniken GmbH, Gauting, Not set

LungenClinic Großhansdorf GmbH, Großhansdorf, Not set

Krankenhaus Martha-Maria Halle-Doelau gGmbH, Halle, Not set

Thoraxklinik Heidelberg gGmbH, Heidelberg, Not set

Lungenklinik Hemer, Hemer, Not set

Universität Des Saarlandes, Homburg, Not set

Lungenfachklinik Immenhausen, Immenhausen, Not set

Uniklinik Schleswig-Holstein, Kiel, Not set

Klinikum Koeln-Merheim, Köln, Not set

SLK Kliniken Heilbronn GmbH, Standort Fachklinik Löwenstein, Löwenstein, Not set

Universitätsklinikum Schleswig-Holstein, Lübeck, Not set

Universität Mannheim, Mannheim, Not set

Klinikum Bogenhausen, München, Not set

Universitätsklinikum Münster, Medizinische Klinik A, Translationale Onkologie, Münster, Not set

Pius Hospital Oldenburg, Oldenburg, Not set

Universitätsklinikum Regensburg, Regensburg, Not set

Klinikum Würzburg Mitte gGmbH, Würzburg, Not set

Uoa Sotiria Hospital, Athens, Not set

Errikos Dynan Hospital, Athens, Not set

Metropolitan Hospital Fourth Oncology Clinic, Faliro, Not set

University Hospital of Larissa, Larissa, Not set

Theageneio Hospital, Thessaloniki, Not set

Ag. Loukas Hospital, Thessaloniki, Not set

Hong Kong Integrated Oncology Centre, Hong Kong, Not set

Queen Mary Hospital, Hong Kong, Not set

Tuen Mun Hospital, Hong Kong, Not set

Prince of Wales Hosp, Shatin, Not set

Az. Osp. Pugliese Ciaccio, Catanzaro, Calabria

AZ.Osp S. Orsola ? Malpighi-Reparto di Oncologia Medica, Bologna, Emilia-Romagna

A.O. Universitaria Di Parma, Parma, Emilia-Romagna

AUSL della Romagna, Ravenna, Emilia-Romagna

Azienda Sanitaria Universitaria Friuli Centrale ? PO Universitario Santa Maria della Misericordia, Udine, Friuli-Venezia Giulia

IRCCS Istituto Regina Elena (IFO), Roma, Lazio

Ospedale Policlinico San Martino, Genova, Liguria

Asst Papa Giovanni XXIII, Bergamo, Lombardia

IRCCS Istituto Clinico Humanitas, Rozzano (MI), Lombardia

A.O.U. Maggiore della Carità, Novara, Piemonte

Irccs Ist. Tumori Giovanni Paolo Ii, Bari, Puglia

Ospedale Civile SS Annunziata, Sassari, Sardegna

AO Ospedali Riuniti Villa Sofia-Cervello-Presidio Ospedaliero Cervello, Palermo, Sicilia

Azienda Ospedaliero-Universitaria Careggi, Firenze, Toscana

Azienda Ospedaliero Universitaria Pisana, Pisa, Toscana

IRCCS Istituto Oncologico Veneto (IOV), Padova, Veneto

Shikoku Cancer Center, Ehime, Not set

Kyushu University Hospital, Fukuoka, Not set

Hokkaido University Hospital, Hokkaido, Not set

Sendai Kousei Hospital, Miyagi, Not set

Niigata Cancer Center Hospital, Niigata, Not set

Okayama University Hospital, Okayama, Not set

Kindai University Hospital, Osaka, Not set

Shizuoka Cancer Center, Shizuoka, Not set

National Cancer Center Hospital, Tokyo, Not set

The Cancer Institute Hospital of JFCR, Tokyo, Not set

Wakayama Medical University Hospital, Wakayama, Not set

Pusan National University Hospital, Busan, Not set

Chungbuk National University Hospital, Cheongju-si, Not set

Kyungpook National University Chilgok Hospital, Daegu, Not set

Keimyung University Dongsan Medical Center, Daegu, Not set

St. Vincent's Hospital, Gyeonggi-do, Not set

Pusan National University Yangsan Hospital, Gyeongsangnam-do, Not set

Gachon University Gil Medical Center, Incheon, Not set

Chonnam National University Hwasun Hospital, Jeollanam-do, Not set

Seoul National University Bundang Hospital, Seongnam-si, Not set

Korea University Anam Hospital, Seoul, Not set

Seoul National University Hospital, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Korea University Guro Hospital, Seoul, Not set

Centro de Infusion E Investigacion Oncologia de Saltillo Sc, Saltillo, Coahuila

Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco

Clínica Integral Internacional de Oncología S de RL de CV, Heroica Puebla de Zaragoza, Puebla

PanAmerican Clinical Research, Querétaro, Santiago de Querétaro, Queretaro

ARKE Estudios Clínicos S.A. de C.V., Ciudad de México, Not set

Jeroen Bosch Ziekenhuis, 'S Hertogenbosch, Not set

Ziekenhuis Rijnstate, Arnhem, Not set

Amphia Ziekenhuis, Breda, Not set

Ziekenhuis St. Jansdal, Harderwijk, Not set

Medisch Centrum Haaglanden, locatie Antoniushove, Leidschendam, Not set

Isala, Zwolle, Not set

Instytut "Centrum Zdrowia Matki Polki", ?ód?, Not set

Kujawsko-Pomorskie Centrum Pulmonologii, Bydgoszcz, Not set

Uniwersyteckie Centrum Kliniczne, Klinika Onkologii i Radioterapii, Gdansk, Not set

Krakowski Szpital Specjalistyczny im sw. Jana Paw?a II, Kraków, Not set

Uniwersytecki Szpital Kliniczny nr 4 w Lublinie, Lublin, Not set

Warminsko-Mazurskie Centrum Chorób P?uc w Olsztynie, Olsztyn, Not set

Wielkopolskie Centrum Pulmonologii i Torakochirurgii w Poznaniu, Poznan, Not set

Radomskie Centrum Onkologii, Radom, Not set

Instytut Gruzlicy I Chorob Pluc, Warszawa, Not set

Narod.Inst.Onkol. im. M.Sklodowskiej - Curie-Panst.Inst.Bad, Warszawa, Not set

Dolno?L?Skie Centrum Onkologii, Pulmonologii I Hematologii, Wroc?aw, Not set

Hospital de Braga, Braga, Not set

CHUC - Unidade de Pneumologia Oncológica, Coimbra, Not set

Centro Clinico Champalimaud, Lisboa, Not set

Centro Hospitalar do Porto ? Hospital de Santo António, Porto, Not set

IPO do Porto, Porto, Not set

National Cancer Centre, Singapore, Not set

Curie Oncology (Farrer), Singapore, Not set

Institut Catala d Oncologia Hospitalet, Hospitalet de Llobregat, Barcelona

Hospital Nuestra Senora de Valme, Seville, Sevilla

Hospital de la Santa Creu i Sant Pau, Barcelona, Not set

Hospital Vall Hebron, Barcelona, Not set

Hospital General Universitario Gregorio Marañon, Madrid, Not set

Hospital Universitario La Paz, Madrid, Not set

Hospital Regional Universitario de Malaga, Malaga, Not set

Hospital Universitario la Fe, Valencia, Not set

Hospital Universitario Miguel Servet, Zaragoza, Not set

Gävle Sjukhus, Gävle, Not set

Hsin-Chu Branch of National Taiwan University Hospital, Hsinchu City, Not set

Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Not set

Chung Shan Medical University Hospital, Taichung, Not set

National Taiwan University Hospital, Taipei, Not set

Taipei Veterans General Hospital, Taipei, Not set

Chang Gung Medical Foundation - Linkou, Taoyuan, Not set

Vajira Hospital, Bangkok, Not set

Siriraj Hospital - Chulabhorn Bone Marrow Transplant Centre, Bangkok, Not set

Srinagarind Hospital, Khon Kaen, Not set

Songklanagarind Hospital, Songkhla, Not set

Blackpool Victoria Hospital, Blackpool, Not set

Addenbrooke's Hospital, Cambridge, Not set

Velindre NHS Trust - Velindre Cancer Centre, Cardiff, Not set

Castle Hill Hospital, Cottingham, Not set

Beatson West of Scotland Cancer Centre, Glasgow, Not set

St James University Hospital, Leeds, Not set

Guy's Hospital - Cancer Centre, London, Not set

Royal Marsden Hospital - London, London, Not set

The Christie NHS Foundation Trust, Manchester, Not set

Nottingham City Hospital, Nottingham, Not set

University Hospitals of North Midlands NHS Trust-Royal Stoke University Hospital, Stoke-On-Trent, Not set

Royal Marsden Hospital (Sutton), Sutton, Not set

Torbay Hospital, Torquay, Not set

Conditions: Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer

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Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial

NCT05722002

Recruiting

This trial is being completed to compare two commonly used options to treat pain after surgery. Participants that undergo gallbladder removal, hernia repair, and breast lump removal will be eligible to enroll. Eligible participants will be randomized to 1 of 2 groups of medications (Non-Steroidal Anti-Inflammatory Drugs (NSAIDS) plus acetaminophen or low dose opioids plus acetaminophen). It is anticipated that the NSAID group will have superior clinical outcomes and fewer side effects when comp... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/01/2025

Locations: University of Michigan, Ann Arbor, Michigan +7 locations

Conditions: Surgery, Pain, Postoperative

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