All Clinical Trials in Canada

A listing of 3914 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

Home

Canada

Show Filters

Match to Clinical Trials

Access to cutting-edge treatments

Latest clinical trials

Find trials in your area

Start Matching

Filter by Age

ADVENT Post Approval Study

NCT06431815

Recruiting

The ADVENT Post Approval Study (PAS) is a prospective, global, multicenter, observational study.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/28/2025

Locations: Mobile Infirmary Medical Center, Mobile, Alabama +33 locations

Mobile Infirmary Medical Center, Mobile, Alabama

Scottsdale Healthcare - Shea, Scottsdale, Arizona

Alta Bates Summit Medical Center, Oakland, California

Washington Hospital Center, Washington, District of Columbia

Florida Heart Rhythm Specialists, PLLC, Fort Lauderdale, Florida

Baptist Medical Center, Jacksonville, Florida

Mount Sinai Medical Center, Miami Beach, Florida

Tallahassee Memorial Hospital, Tallahassee, Florida

AdventHealth Tampa, Tampa, Florida

Memorial Health University Medical Center, Savannah, Georgia

Ochsner Clinic Foundation, New Orleans, Louisiana

Beth Israel Deaconess Medical Center, Boston, Massachusetts

University of Mississippi Medical Center, Jackson, Mississippi

Montefiore Medical Center, Bronx, New York

New York Hospital Queens, Flushing, New York

Columbia University Medical Center, New York, New York

Northwell Health, New York, New York

East Carolina University Medical Center, Greenville, North Carolina

Pinnacle Health at Harrisburg Hospital, Harrisburg, Pennsylvania

Medical University of South Carolina, Charleston, South Carolina

Prisma Health Richland Hospital, Columbia, South Carolina

Vanderbilt University Medical Center, Nashville, Tennessee

University of Texas Medical Branch, Galveston, Texas

University of Texas Houston Health Science Center, Houston, Texas

Orion Medical, Houston, Texas

Sentara Norfolk General Hospital, Norfolk, Virginia

University of Washington Medical Center, Seattle, Washington

Sos Cardio Servicoshospitalares Ltda, Florianópolis, Santa Catarina

Instituto do Coração do HCFMUSP, São Paulo, Sao Paulo

Southlake Regional General Hospital, Newmarket, Ontario

Institut de Cardiologie de Montreal-Hospital, Montréal, Quebec

Institut universitaire de Cardiologie et de Pneumologie de Quebec, Québec, Quebec

Hospital Regional de Concepcion, Concepción, Biobio

Fundacion Cardio-Infantil-Hospital, Bogotá, Not set

Conditions: Paroxysmal Atrial Fibrillation

Learn More ›

A Study to Evaluate the Effect of Budesonide, Glycopyrronium, Formoterol Fumarate (BGF) Metered Dose Inhaler (MDI), Budesonide and Formoterol Fumarate (BFF) MDI and Placebo MDI on Exercise Parameters in Participants With Chronic Obstructive Pulmonary Disease (COPD).

NCT06067828

Recruiting

This study will investigate the effect of Budesonide, Glycopyrronium, and Formoterol Fumarate (BGF) metered dose inhaler (MDI) compared with Placebo MDI, and Budesonide and Formoterol Fumarate (BFF) MDI on isotime inspiratory capacity (IC) and exercise endurance time.

Gender:

ALL

Ages:

Between 40 years and 80 years

Trial Updated:

07/28/2025

Locations: Research Site, Los Angeles, California +36 locations

Research Site, Los Angeles, California

Research Site, Tarzana, California

Research Site, Torrance, California

Research Site, Brooksville, Florida

Research Site, Anderson, South Carolina

Research Site, Greenville, South Carolina

Research Site, Spartanburg, South Carolina

Research Site, Caba, Not set

Research Site, Quilmes, Not set

Research Site, Edmonton, Alberta

Research Site, Kingston, Ontario

Research Site, Sainte Foy, Quebec

Research Site, Guangzhou, Not set

Research Site, Nanchang, Not set

Research Site, Shenyang, Not set

Research Site, Zhengzhou, Not set

Research Site, Berlin, Not set

Research Site, Frankfurt, Not set

Research Site, Großhansdorf, Not set

Research Site, Hannover, Not set

Research Site, Heidelberg, Not set

Research Site, Lübeck, Not set

Research Site, Mainz, Not set

Research Site, Daegu, Not set

Research Site, Seoul, Not set

Research Site, Benalmádena, Not set

Research Site, Madrid, Not set

Research Site, Santiago de Compostela, Not set

Research Site, Sevilla, Not set

Research Site, Leeds, Not set

Research Site, Leicester, Not set

Research Site, London, Not set

Research Site, Manchester, Not set

Conditions: Chronic Obstructive Pulmonary Disease

Learn More ›

A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Progressive Pulmonary Fibrosis

NCT06025578

Recruiting

The purpose of this study is to evaluate the efficacy, safety, and tolerability of BMS-986278 in Participants with Progressive Pulmonary Fibrosis.

Gender:

ALL

Ages:

21 years and above

Trial Updated:

07/28/2025

Locations: The University of Alabama at Birmingham, Birmingham, Alabama +533 locations

The University of Alabama at Birmingham, Birmingham, Alabama

Local Institution - 0416, Phoenix, Arizona

St. Joseph's Hospital and Medical Center, Phoenix, Arizona

Local Institution - 0526, Tucson, Arizona

Scripps Clinic Torrey Pines, La Jolla, California

Local Institution - 0066, La Jolla, California

University of Southern California (USC) - Keck School of Medicine (KSOM) - Transplant Clinic, Los Angeles, California

David Geffen School of Medicine at UCLA, Los Angeles, California

UC Irvine Medical Center, Orange, California

University of California UC Davis Medical Center, Sacramento, California

University of California, San Francisco Medical Center- Pulmonary Practice, San Francisco, California

Stanford Hospital and Clinics, Stanford, California

University of Colorado Anschutz Medical Campus - Department of Family Medicine, Aurora, Colorado

National Jewish Health, Denver, Colorado

Yale New Haven Hospital, New Haven, Connecticut

Stamford Health Medical Group - Stamford - 29 Hospital Plaza Suite 605, Stamford, Connecticut

Christiana Care Pulmonary Associates - Newark, Newark, Delaware

Medstar Georgetown University Hospital, Washington, District of Columbia

Meris Clinical Research, Brandon, Florida

Florida Lung, Asthma and Sleep Specialists - Celebration, Celebration, Florida

St Francis Sleep Allergy & Lung Institute, Clearwater, Florida

Omega Research Consultants LLC, DeBary, Florida

Malcom Randall VA Medical Center, Gainesville, Florida

University of Florida (UF) Health Shands Hospital, Gainesville, Florida

Pulmonary Specialists of the Palm Beaches, Loxahatchee Groves, Florida

Local Institution - 0347, Miami, Florida

Local Institution - 0517, Miami, Florida

Local Institution - 0220, Ocala, Florida

Avanza Medical Research Center, Pensacola, Florida

Coastal Pulmonary & Critical Care, P.L.C., Saint Petersburg, Florida

Tampa General Hospital, Tampa, Florida

Local Institution - 0378, Weston, Florida

Emory Clinic, Atlanta, Georgia

Local Institution - 0465, Austell, Georgia

Pulmonology, Sleep, Asthma & Allergy Center of Dublin, Dublin, Georgia

Northwestern Memorial Hospital, Chicago, Illinois

Local Institution - 0346, Chicago, Illinois

The University of Chicago Medicine, Chicago, Illinois

Local Institution - 0040, Evanston, Illinois

Loyola University Health System, Maywood, Illinois

Local Institution - 0441, Indianapolis, Indiana

University of Iowa Hospitals and Clinics, Iowa City, Iowa

University of Kansas Medical Center (KUMC), Kansas City, Kansas

Local Institution - 0045, Louisville, Kentucky

Norton Healthcare, Inc., Louisville, Kentucky

University of Maryland - Marlene and Stewart Greenebaum Cancer Center, Baltimore, Maryland

Local Institution - 0033, Towson, Maryland

Massachusetts General Hospital, Boston, Massachusetts

Local Institution - 0436, Boston, Massachusetts

Local Institution - 0069, Boston, Massachusetts

Local Institution - 0079, Springfield, Massachusetts

University of Michigan Health System - A. Alfred Taubman Health Care Center - Pulmonary Clinic, Ann Arbor, Michigan

Local Institution - 0031, Detroit, Michigan

Spectrum Health Medical Group Pulmonary, Grand Rapids, Michigan

Local Institution - 0509, Royal Oak, Michigan

M Health Fairview University of Minnesota Medical Center - CSC - Center for Lung Science and Health, Minneapolis, Minnesota

The Lung Research Center, Chesterfield, Missouri

Washington University School of Medicine in St. Louis, Saint Louis, Missouri

Local Institution - 0525, Reno, Nevada

Local Institution - 0371, Newark, New Jersey

Northern Westchester Hospital, Mount Kisco, New York

Local Institution - 0503, New York, New York

Icahn School of Medicine at Mount Sinai, New York, New York

Duke University Medical Center, Durham, North Carolina

Accellacare US Inc. of Wilmington, Wilmington, North Carolina

Southeastern Research Center, Winston-Salem, North Carolina

University of Cincinnati College Of Medicine, Cincinnati, Ohio

University Hospitals Cleveland Medical Center, Cleveland, Ohio

The Ohio State University Wexner Medical Center, Columbus, Ohio

Mercy St. Vincent Medical Center, Toledo, Ohio

OU Health Sciences Center - OU Health Physicians - Cardiology, Pulmonary & Vascular Medicine Clinic, Oklahoma City, Oklahoma

Layrek Clinical Research, Tulsa, Oklahoma

Oregon Health & Science University - Pulmonary Clinic, Portland, Oregon

Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania

Penn Medicine - Perelman Center for Advanced Medicine, Philadelphia, Pennsylvania

Thomas Jefferson University Hospital - Jane and Leonard Korman Lung Center, Philadelphia, Pennsylvania

Temple University Hospital (TUH) - Temple Lung Center (TLC), Philadelphia, Pennsylvania

Local Institution - 0466, Pittsburgh, Pennsylvania

Pulmonology Associates - Wynnewood, Wynnewood, Pennsylvania

AnMed Health Oglesby Center - AnMed Health Pulmonary and Sleep Medicine, Anderson, South Carolina

Medical University of South Carolina- College of Medicine, Charleston, South Carolina

Velocity Clinical Research Inc., Greenville, South Carolina

Local Institution - 0469, Rock Hill, South Carolina

Local Institution - 0363, Nashville, Tennessee

Local Institution - 0356, Nashville, Tennessee

University of Texas Southwestern Medical Center - Pulmonary Specialty Clinic, Dallas, Texas

Baylor University Medical Center at Dallas, Dallas, Texas

Baylor College of Medicine Medical Center - Pulmonary, Critical Care, and Sleep Medicine, Houston, Texas

McGovern Medical School - UT Physicians - Pulmonary Medicine - Texas Medical Center Location, Houston, Texas

Metroplex Pulmonary and Sleep Center, McKinney, Texas

South Texas Veterans Health Care System - Audie L. Murphy VA Hospital, San Antonio, Texas

University of Utah, University Hospital, Salt Lake City, Utah

The University of Vermont, Burlington, Vermont

Local Institution - 0505, Falls Church, Virginia

VCU Medical Center, Richmond, Virginia

Western Washington Medical Group (WWMG) - Everett - Silver Lake Medical Center Location, Everett, Washington

University of Washington Medical Center, Seattle, Washington

Local Institution - 0395, Milwaukee, Wisconsin

Instituto De Enfermedades Respiratorias E Investigacion Medica (IERIM), Florencio Varela, Buenos Aires

Fundacion Enfisema - Instituto Ave Pulmo, Mar Del Plata, Buenos Aires

Fundacion Respirar, Buenos Aires, B

Consultorios Médicos del Buen Ayre, Caba, B

Centro Medico de Enfermedades Respiratorias, Florida, B

Clinica 25 de Mayo, Mar del Plata, B

Centro Respiratorio Quilmes, Quilmes, Provincia De Buenos Aires, B

Hospital Italiano de Buenos Aires, Ciudad Autónoma Buenos Aires, C

Instituto Medico DAMIC, Cordoba, Córdoba

Respira Salud Clinica Integral, Godoy Cruz, M

Instituto Medico INSARES SA, Mendoza, M

Instituto Medico de la Fundacion de Estudios Clínicos, Rosario, S

Investigaciones en Patologias Respiratorias, San Miguel De Tucuman, Tucumán, T

Centro de Investigaciones Metabólicas (CINME), Ciudad Autónoma de Buenos Aires, Not set

Ibamedica, Santa Fe, Not set

Royal Prince Alfred Hospital, Camperdown, New South Wales

Local Institution - 0467, Darlinghurst, New South Wales

Westmead Hospital, Westmead, New South Wales

Local Institution - 0090, Brisbane, Queensland

Local Institution - 0499, Chermside, Queensland

Gallipoli Medical Research Centre - Clinical Trials Unit (CTU), Greenslopes, Queensland

Mater Misericordiae Limited, South Brisbane, Queensland

Local Institution - 0275, Adelaide, South Australia

Eastern Health, Box Hill, Victoria

Local Institution - 0299, Heidelberg,VIC, Victoria

Local Institution - 0059, Melbourne, Victoria

Local Institution - 0303, Murdoch, Western Australia

Institute for Respiratory Health, Nedlands, Western Australia

Kepler Universitatsklinikum, Linz, Oberoesterreich

SALK - Universitatsklinik Fur Pneumologie/ Lungenheilkunde Landeskrankenhaus, Salzburg, Salzburger Land

Local Institution - 0473, Graz, Styria

Local Institution - 0241, Vienna, Not set

Krankenhaus Hietzing, Vienna, Not set

Wiener Gesundheitsverbund - Klinik Floridsdorf, Wien, Not set

CHU UCL Namur - Mont-Godinne, Yvoir, Namur

Local Institution - 0391, Edegem, VAN

UZ Leuven, Leuven, VBR

Cliniques Universitaires Saint-Luc, Brussels, Not set

Vzw Az Groeninge, Kortrijk, Not set

Centre Hospitalier Universitaire de Liège - Sart Tilman, Liege, Not set

Local Institution - 0304, Salvador, Bahia

Local Institution - 0512, Salvador, BA

Hospital das Clínicas da Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG

Hospital Madre Teresa, Belo Horizonte, Minas Gerais

Centro Medico Santa Maria, Barra Mansa, Rio De Janeiro

Hospital Ernesto Dornelles (HED), Porto Alegre, Rio Grande Do Sul

WM Clinica Pneumologica Sociedade Simples LTDA, Porto Alegre, RIO Grande DO SUL

Policlínica Piquet Carneiro, Universidade do Estado do Rio de Janeiro, Rio De Janeiro, RJ

Santa Casa de Misericórdia de Porto Alegre - Hospital Sao Jose, Porto Alegre, RS

Local Institution - 0476, Engenho Velho da Federacao, Salvador

Centro de Estudos de Pneumologia da Faculdade de Medicina do ABC (CEPFMABC), Santo André, SAO Paulo

Hospital Dia do Pulmão, Blumenau, SC

Universidade Estadual Paulista - Hospital das Clinicas da Faculdade de Medicina de Botucatu (HCFMB), Botucatu, SP

CEMEC - Centro Multidisciplinar de Estudos Clínicos, São Bernardo Do Campo, SP

Hospital São Lucas da PUCRS, Porto Alegre, Not set

Hospital Alemao Oswaldo Cruz (HAOC) - Centro de Oncologia (Oncology Center), Sao Paulo, Not set

Local Institution - 0006, São Paulo, Not set

Local Institution - 0385, Edmonton, Alberta

Synergy Respiratory & Cardiac Care, Sherwood Park, Alberta

Kelowna Respiratory & Allergy Clinic, Kelowna, British Columbia

The Lung Centre, Vancouver, British Columbia

St. Paul's Hospital, Vancouver, British Columbia

Local Institution - 0053, Burlington, Ontario

St. Joseph's Healthcare Hamilton, Hamilton, Ontario

Brightshores Health System, Owen Sound, Ontario

Inspiration Research, Toronto, Ontario

Local Institution - 0529, Greenfield Park, Quebec

Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, Quebec

C.I.C. Joliette, Saint-Charles-Borromee, Quebec

Local Institution - 0099, Sherbrooke, Quebec

C.I.C. Mauricie Inc., Trois-Rivieres, Quebec

Diex Recherche - Trois-Rivieres, Trois-Rivieres, Quebec

Local Institution - 0102, Quebec, Not set

Bioreuma, Concepcion, Bio Bio

Local Institution - 0093, Talcahuano, BI

Centro de Investigacion Curico, Curico, Maule

Centro de Investigación del Maule, Talca, Maule

Clínica Universidad de los Andes, Santiago, RM

CEC Centros Estudios Clinicos, Santiago, RM

CENRESIN - Centro Respiratorio Integral, Quillota, Valparaiso

Local Institution - 0530, Vina del Mar, Valparaiso

Local Institution - 0447, Santiago, Not set

Local Institution - 0468, Santiago, Not set

OncoCentro - Vina del Mar, Vina del Mar, Not set

Anhui Medical University - Anhui Chest Hospital, Hefei, AH

Beijing Chaoyang Hospital, Capital Medical University, Beijing, Beijing

Beijing Friendship Hospital, Capital Medical University, Beijing, Beijing

Peking Union Medical College Hospital, Beijing, Beijing

The First Hospital of Lanzhou University, Lanzhou, Gansu

The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Shi, Guangdong

The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong

Nanfang Hospital of Southern Medical University, Guangzhou, Guangdong

Shenzhen People's Hospital, Shenzhen Shi, Guangdong

Peking University Shenzhen Hospital, Shenzhen, Guangdong

Henan Provincial People's Hospital, Zhengzhou, Hainan

Yichang Central People's Hospital - Xiling Campus, Yichang Shi, Hebei

The Second Hospital of Hebei Medical University, Shijiazhuang, Hebi

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei

Renmin Hospital of Wuhan University, Wuhan, HUB

The First Affiliated Hospital of Zhengzhou University, Zhengzhou Shi, Hunan

Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu

Local Institution - 0424, Suzhou Shi, Jiangsu

The First Affiliated Hospital of Soochow University, Suzhou Shi, Jiangsu

Wuxi People's Hospital, Wuxi, Jiangsu

The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu

The First Affiliated Hospital of Nanchang University - Xianghu District, Nanchang, Jiangxi

The First Hospital of China Medical University, Shenyang, Liaoning

Shenyang Chest Hospital, Shenyang, Liaoning

Xi'an International Medical Center Hospital, XI'an, Shan3xi

Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Shi, Shanghai Sheng

Huadong Hospital Affiliated to Fudan University, Shanghai, Shanghai

Shanghai Jiao Tong University - Shanghai Chest Hospital, Shanghai, Shanghai

Local Institution - 0098, Shanghai, Shanghai

Shanghai Pulmonary Hospital, Shanghai, Shanghai

Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine - South Branch, Shanghai, Shanghai

West China Hospital, Sichuan University, Chengdu, Sichuan

Tianjin Medical University General Hospital, Tianjin, Tianjin

Tianjin Chest Hospital, Tianjin, Tianjin

General Hospital of Ningxia Medical University, Ningxia, Yinchuan

The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou Shi, Zhejiang

Local Institution - 0427, Hangzhou, Zhejiang

Hangzhou First People's Hospital, Hangzhou, Zhejiang

Sir Run Run Shaw Hospital - Zhejiang University School of Medicine, Hangzhou, Zhejiang

The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang

The Second Xiangya Hospital of Central South University, Changsha, Not set

Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu Shi, Not set

Anhui Provincial Hospital, Hefei Shi, Not set

The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Not set

Qilu Hospital of Shandong University, Jinan Shi, Not set

Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai, Not set

The Third Hospital of Hebei Medical University, Shijiazhuang, Not set

Servicios de Salud IPS Suramericana S.A.S - IPS Sura Industriales Medellín, Medellin, ANT

Local Institution - 0515, Medellín, ANT

Medicos Internistas de Caldas, Manizales, CL

Hospital Universitario San Ignacio, Bogota, Cundinamarca

Healthy Medical Center, Zipaquira, Cundinamarca

Health SURA Calle 100, Bogota, DC

Fundación Neumológica Colombiana, Bogotá, DC

Instituto Neumologico del Oriente, Floridablanca, Santander

Health SURA Chipichape, Santiago De Cali, VAC

Fundacion Santa Fe de Bogota, Bogota, Not set

Local Institution - 0256, Olomouc, OL

Local Institution - 0238, Prague, Not set

Local Institution - 0110, Aarhus, Region Midtjylland

Odense Universitetshospital - Svendborg Sygehus, Odense C, Region Syddanmark

Rigshospitalet, Copenhagen, Not set

Gentofte Hospital, Hellerup, Not set

Helsinki University Hospital Heart and Lung Center, Helsinki, Etelae-Suomen Laeaeni

Turun Yliopistollinen Keskussairaala (TYKS), Turku, Laensi-Suomen Laeaeni

Hospices Civils De Lyon, Bron, Auvergne-Rhône-Alpes

Centre Hospitalier Universitaire Grenoble Alpes (CHU Grenoble Alpes), Grenoble, Auvergne-Rhône-Alpes

Local Institution - 0534, Angers, Pays De La Loire

CHU de Nantes - Hôpital Nord Laennec, Nantes Cedex 01, Pays De La Loire

Assistance Publique Hopitaux de Marseille - Hopital Nord, Marseille, Provence-Alpes-Côte d'Azur

Hôpital Avicenne, Bobigny, Not set

CHU de Brest - Hôpital Cavale Blanche, Brest, Not set

CHU Dijon - Hôpital François Mitterrand, Dijon Cedex, Not set

Local Institution - 0252, Lille CEDEX, Not set

CHU de Nice - Hôpital Pasteur, Nice, Not set

Local Institution - 0331, Paris, Not set

CHU Hopitaux de Bordeaux - Hopital Haut-Leveque, Pessac, Not set

Local Institution - 0360, Rennes, Not set

Hôpital Larrey, Toulouse, Not set

CHRU de Tours - Hôpital Bretonneau, Tours, Not set

Hôpital Bichat - Claude-Bernard, Paris, Île-de-France

Local Institution - 0533, Konstanz, Baden-Wurttemberg

Klinikum der Universität München, Munich, Bavaria

HELIOS Klinikum Emil von Behring, Berlin, BE

Universitaetsklinikum Freiburg - Klinik fuer Pneumologie, Freiburg I. Breisgau, BW

Local Institution - 0294, Stuttgart, BW

Local Institution - 0125, Wangen I. Allgaeu, BW

Thoraxzentrum Bezirk Unterfranken, Munnerstadt, BY

Lungenfachklinik Immenhausen, Immenhausen, HE

Helios Hanseklinikum Stralsund, Stralsund, MV

Universitaetsklinikum Essen - Ruhrlandklinik, Essen, Nordrhein Westfalen

Krankenhaus der Augustinerinnen- Klinik fuer Pneumologie, Allergologie, Schlaf- und Beatmungsmedizin, Cologne, Northwest

Local Institution - 0142, Munster, Northwest

Velocity Clinical Research Germany GmbH, Ahrensburg, Not set

Vivantes Klinikum Neukölln, Berlin, Not set

Fachkrankenhaus Coswig GmbH, Coswig, Not set

Universitätsklinikum Hamburg-Eppendorf (UKE), Hamburg, Not set

Thoraxklinik-Heidelberg gGmbH, Heidelberg, Not set

Universitaetsklinikum Leipzig - Klinik und Poliklinik fuer Pneumologie, Leipzig, Not set

Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz, Not set

Athens Medical Center, Maroussi, Attica

University Hospital of Ioannina, Ioannina, Epirus

University General Hospital of Heraklion, Heraklion, Iraklio Kritis

Local Institution - 0464, Pilea Chortiatis, Thessaloniki

University General Hospital Attikon, Athens, Not set

"Corfu General Hospital ""St. IRINI""", Corfu, Not set

University of Thessaly- General University Hospital of Larissa, Larisa, Not set

University of Patras - Rio Regional University Hospital, Rio, Not set

General Hospital of Thessaloniki - Papageorgiou, Thessaloniki, Not set

Semmelweis Egyetem Pulmonologiai Klinika, Budapest, Not set

Gyor-Moson-Sopron Varmegyei Petz Aladar Egyetemi Oktato Korhaz, Gyor, Not set

All India Institute of Medical Sciences (AIIMS) - New Delhi, New Delhi, Delhi

Max Super Specialty Hospital, Saket - West Block - A Unit of Max Healthcare Institute Limited, New Delhi, DL

Unity Hospital, Surat, GJ

Local Institution - 0407, Ahmedabad, Gujarat

Marengo CIMS Hospital, Ahmedabad, Gujarat

Local Institution - 0491, Vadodara, Gujarat

K.L.E.S. Dr. Prabhakar Kore Hospital & Medical Research Centre, Belagavi, KA

Jehangir Clinical Development Center, Pune, Maharashtra

Local Institution - 0335, Nagpur, MH

Local Institution - 0245, Nagpur, MH

Local Institution - 0457, Nagpur, MH

Getwell Hospital and Research Institute - Lungs Care, Nagpur, MH

Grant Medical Foundation - Ruby Hall Clinic, Pune, MH

ACE Hospital & Research Center, Pune, MH

Local Institution - 0276, Pune, MH

Green City Hospital, Bhopal, MP

Fortis Hospital Mohali, Mohali, Punjab

Local Institution - 0527, Jaipur, Rajasthan

Local Institution - 0247, Jaipur, RJ

Asthma Bhawan, Jaipur, RJ

Local Institution - 0528, Hyderabad, TG

Local Institution - 0471, Coimbatore, TN

Local Institution - 0398, Noida, UP

Local Institution - 0490, Lucknow, Uttar Pradesh

Shri Guru Ram Rai (SGRR) Institute of Medical and Health Sciences - Shri Mahant Indiresh Hospital, Dehradun, UT

Nilratan Sircar (NRS) Medical College & Hospital, Kolkata, WB

The Calcutta Medical Research Institute (CMRI), Kolkata, WB

St. John's Medical College, Bangalore, Not set

Midland Healthcare & Research Center, Lucknow, Not set

Our Lady of Lourdes Hospital - Drogheda, Drogheda, LH

St. Vincent's University Hospital, Dublin 4, Not set

Connolly Hospital Blanchardstown, Dublin, Not set

Tallaght University Hospital, Dublin, Not set

Kaplan Medical Center, Rehovot, Central District

Ben-Gurion University of the Negev - Soroka University Medical Center, Be'er Sheva, D

Carmel Medical Center, Haifa, HA

Shamir Medical Center, Be'er Ya'akov, M

Tel Aviv Sourasky Medical Center, Tel Aviv, TA

Rambam Health Care Campus - Pulmonology, Haifa, Not set

Hadassah Medical Center (HMC) - Hadassah University Hospital (HUH) - Ein Kerem, Jerusalem, Not set

Rabin Medical Center - Hasharon Hospital, Petah-Tikva, Not set

Azienda Ospedaliero Universitaria delle Marche, Ancona, AN

Azienda Ospedaliero - Universitaria di Modena Policlinico, Modena, Emilia-Romagna

Azienda Ospedaliero-Universitaria Careggi, Firenze, FI

Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milano, MI

Local Institution - 0251, Milano, MI

Azienda Ospedaliero Universitaria Pisana, Pisa, PI

Fondazione Policlinico Universitario Agostino Gemelli, Roma, RM

Local Institution - 0166, Trieste, TS

ASST Papa Giovanni XXIII, Bergamo, Not set

Ospedale Colonnello D'Avanzo Foggia, Foggia, Not set

"Ospedale ""Gian Battista Morgagni - Luigi Pierantoni"" di Forli", Forli, Not set

Local Institution - 0383, Milano, Not set

Azienda Ospedaliera San Paolo, Milan, Not set

Fondazione IRCCS San Gerardo dei Tintori, Monza, Not set

AORN - Ospedali dei Colli Ospedale V. Monaldi, Napoli, Not set

Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione (ISMETT), Palermo, Not set

Fondazione IRCCS Policlinico San Matteo, Pavia, Not set

Azienda Ospedaliera Universitaria - Universita di Sassari, Sassari, Not set

Ospedale Policlinico di Siena, Siena, Not set

Nagoya University Hospital, Showa-Ku, Aichi-Ken

Chiba University Hospital, Chiba-Shi, Chiba

Kameda Medical Center - Kameda Clinic, Kamogawa-shi, Chiba

University of Fukui Hospital, Yoshida-gun, Fukui

Fukuoka University - Chikushi Hospital, Chikushino-shi, Fukuoka

National Hospital Organization Kyushu Medical Center, Fukuoka-Shi, Fukuoka

Kyushu University Hospital, Fukuoka-shi, Fukuoka

Local Institution - 0423, Kitakyushu-shi, Fukuoka

Jizankai Medical Foundation Tsuboi Cancer Center Hospital, Koriyama-shi, Fukushima

National Hospital Organization Ibarakihigashi National Hospital, Naka-gun, Gunma

Hiroshima Prefectural Hospital, Hiroshima-shi, Hirohima-ken

Sapporo Medical University Hospital, Sapporo, Hokkaido

Hokkaido University Hospital, Sapporo, Hokkaido

National Hospital Organization Himeji Medical Center, Himeji-Shi, Hyogo

Kobe City Medical Center General Hospital, Kobe, Hyogo

Kitasato University Hospital, Sagamihara, Kanagawa

Matsusaka Municipal Hospital, Matsusaka-shi, Mie

Kindai University Hospital, Osakasayama-shi, Osaka

National Hospital Organization Kinki-chuo Chest Medical Center, Sakai City, OSK

Hamamatsu University Hospital, Hamamatsu-shi, Shizuoka

Juntendo University Hospital, Bunkyo-Ku, TKY

Jichi Medical University Hospital, Shimotsuge-shi, Tochigi

Local Institution - 0230, Tokushina-Shi, Tokushima-Ken

Kyorin University Hospital, Mitaka-shi, Tokyo-to

Institute of Science Tokyo Hospital, Bunkyo-Ku, Tokyo

Nippon Medical School Hospital, Bunkyo-ku, Tokyo

Toho University Ohashi Medical Center, Meguro-ku, Tokyo

Toranomon Hospital, Minato-ku, Tokyo

The Jikei University Hospital, Minato-ku, Tokyo

Keio University Hospital, Shinjuku-ku, Tokyo

Tokyo Women's Medical University Hospital, Shinjuku-Ku, Tokyo

National Hospital Organization - Yamaguchi-Ube Medical Center, Ube-shi, Yamaguchi-Ken

Local Institution - 0228, Bunkyo-Ku, Not set

Kurume University Hospital, Fukuoka, Not set

Aso Iizuka Hospital, Iizuka-shi, Not set

Shimane University Hospital, Izumo-Shi, Not set

Saiseikai Kumamoto Hospital, Kumamoto, Not set

Nagasaki University Hospital, Nagasaki-Shi, Not set

Tosei General Hospital, Seto, Not set

Tokyo Medical University Hospital, Shinjuku-Ku, Not set

Center Hospital of the National Center for Global Health and Medicine, Shinjyu-Ku, Not set

Osaka Medical and Pharmaceutical University Hospital, Takatsuki-Shi, Not set

Tenri Hospital, Tenri-Shi, Not set

Toho University - Omori Medical Center, Tokyo, Not set

Fujita Health University Hospital, Toyoake-Shi, Not set

Kanagawa Cardiovascular and Respiratory Center, Yokohama-Shi, Not set

Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-Do

Myongji Hospital, Goyang-si, Gyeonggi

Seoul National University Hospital, Jongno-gu, Seoul

Asan Medical Center (AMC), Songpa-gu, Seoul

SoonChunHyang University Seoul Hospital, Yongsan-gu, Seoul

Ulsan University Hospital (UUH), Dong-gu, Ulsan

SoonChunHyang University Bucheon Hospital, Bucheon-Si, Not set

The Catholic University of Korea, Bucheon St. Mary's Hospital, Bucheonsi Weonmigu, Not set

Inje University Busan Paik Hospital, Busan, Not set

Seoul National University Bundang Hospital, Gyeonggi-do, Not set

Inje University Haeundae Paik Hospital, Haeundae-Gu, Not set

Wonkwang University Hospital, Iksansi, Not set

Gachon University - Gil Medical Center, Incheon, Not set

Yonsei University Health System, Severance Hospital, Seoul, Not set

Local Institution - 0332, Seoul, Not set

Ajou University Hospital, Suwon, Not set

Local Institution - 0483, Kajang, Selangor Darul Ehsan

Local Institution - 0482, Cheras, Wilayah Persekutuan Kuala Lumpur

Local Institution - 0480, Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur

Local Institution - 0484, Kuching, Not set

Local Institution - 0218, Aguascalientes, AGU

Local Institution - 0411, Ciudad De México, Cdmx

Local Institution - 0521, México, DIF

Centro de Investigacion Clinica en Mexico (CIMeT), Guadalajara, Jalisco

Local Institution - 0194, Guadalajara, JAL

Local Institution - 0445, Guadalajara, JAL

Centro de Investigación Clínica Chapultepec S.A. de C.V., Morelia, MIC

Local Institution - 0078, Monterrey, Nuevo León

Oaxaca Site Management Organization (OSMO), Oaxaca, OAX

Centro de Investigacion Clinica de Oaxaca (CICLO), Oaxaca, OAX

Local Institution - 0030, Córdoba, VER

Medical Care & Research S.A. de C.V., Mérida, YUC

Mérida Investigación Clínica, Mérida, YUC

Local Institution - 0493, Chihuahua, Not set

Local Institution - 0362, Guadalajara, Not set

Local Institution - 0007, Mexico City, Not set

Leids Universitair Medisch Centrum, Leiden, South Holland

Erasmus MC - Centrum voor Interstitiele Longziekten, Rotterdam, South Holland

St. Antonius Ziekenhuis, Nieuwegein, Utrecht

Amsterdam UMC - Locatie VUMC - Pulmonale Hypertensie (PH) Kenniscentrum, Amsterdam, Not set

Local Institution - 0338, Amsterdam, Not set

Zuyderland Medisch Centrum, Sittard-Geleen, Heerlen, Not set

Local Institution - 0369, San Borja, Lima

Local Institution - 0412, Lima, LIM

Local Institution - 0022, Lima, LIM

Local Institution - 0409, Lima, LIM

Local Institution - 0225, San Miguel, LIM

Local Institution - 0077, Piura, PIU

Local Institution - 0012, Lima, Not set

Hospital Nacional Cayetano Heredia, Lima, Not set

MICS Centrum Medyczne Bydgoszcz, Bydgoszcz, KP

NZOZ Przychodnia Vitamed, Bydgoszcz, KP

Local Institution - 0259, Krakow, Malopolskie

Local Institution - 0516, Warszawa, MZ

Centrum Medycyny Oddechowej, Bialystok, PD

Uniwersyteckie Centrum Kliniczne, Gdansk, Pomorskie

Warminsko-Mazurskie Centrum Chorób Pluc w Olsztynie, Olsztyn, WN

Local Institution - 0153, Bedzin, Not set

Local Institution - 0131, Katowice, Not set

Uniwersytecki Szpital Kliniczny Nr. 1 im. Norberta Barlickiego, Lodz, Not set

Local Institution - 0520, Lodz, Not set

Unidade Local de Saude Braga, Braga, Not set

Hospital de Santa Marta, Lisboa, Not set

Hospital CUF Tejo, Lisboa, Not set

Unidade Local de Saude de Santa Maria, EPE - Hospital Pulido Valente, Lisboa, Not set

Unidade Local de Saude de Loures - Odivelas, E. P. E., Loures, Not set

Unidade Local de Saude de Santo Antonio, E.P.E., Porto, Not set

Unidade Local de Saude de Sao Joao, EPE - Hospital de Sao Joao, Porto, Not set

Unidade Local de Saude de Gaia/Espinho, EPE, Vila Nova de Gaia, Not set

Alliance Pulmonary Group, Guaynabo, Not set

Local Institution - 0463, Guaynabo, Not set

Hospital Universitario Central de Asturias, Oviedo, Asturias

Local Institution - 0169, Badalona, B

Hospital Universitario Vall d'Hebron, Barcelona, B

Hospital Universitario Marqués de Valdecilla, Santander, CB

Santiago Clinic Hospital (Hospital Clínico Universitario de Santiago -CHUS), Santiago de Compostela, Galicia

Hospital Universitario Virgen de la Victoria, Málaga, MA

Hospital Universitario de la Princesa, Madrid, M

Hospital Clínico San Carlos, Madrid, M

Hospital Universitario La Paz, Madrid, M

Hospital Universitario Puerta de Hierro - Majadahonda, Majadahonda, M

Local Institution - 0197, Valencia, V

Giromed Institute, SLP, Barcelona, Not set

Hospital Clínic de Barcelona, Barcelona, Not set

Hospital Universitari de Bellvitge (IDIBELL), Barcelona, Not set

Clínica Universidad de Navarra -Madrid, Madrid, Not set

Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set

Hospital Clinico Universitario, Madrid, Not set

Clínica Universidad de Navarra, Pamplona, Not set

Local Institution - 0470, Santa Cruz de Tenerife, Not set

Inselspital - Universitaetsklinik Bern für Pneumologie, Bern, BE

Universitätsspital Basel, Basel, BS

Hopitaux Universitaires de Geneve (HUG), Genève, Geneve

Local Institution - 0478, St Gallen, Not set

Changhua Christian Hospital, Changhua, CHA

Chang Gung Medical Foundation - Kaohsiung Branch, Kaohsiung, Kao-Hsiung

Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Sanmin District

China Medical University Hospital, Taichung, TXG

National Taiwan University Hospital Yun-Lin Branch, Douliu Shi, YUN

Taichung Veterans General Hospital, Taichung, Not set

Taipei Veterans General Hospital, Taipei City, Not set

National Taiwan University Hospital - The National Center of Excellence for Clinical Trial, Taipei, Not set

Local Institution - 0481, Bangkok-Noi, Bangkok

Local Institution - 0485, Mueang Chiang Mai, Chiang Mai

Local Institution - 0487, Muang Khon Kaen, Khon Kaen

Local Institution - 0488, Hatyai, Songkla

Local Institution - 0479, Bangkok, Not set

Local Institution - 0420, Saricam, Adana

Local Institution - 0367, Ueskuedar, Istanbul

Local Institution - 0437, Ankara, Not set

Local Institution - 0191, Bursa, Not set

Local Institution - 0224, Guemueshane, Not set

Local Institution - 0215, Izmir, Not set

Local Institution - 0222, Izmir, Not set

Local Institution - 0397, Keçiören/Ankara, Not set

Local Institution - 0181, Maltepe, Not set

Local Institution - 0200, Pasaport, Not set

Local Institution - 0456, Pasaport, Not set

Local Institution - 0281, Topkapı, Not set

University Hospitals Birmingham NHS Foundation Trust - Heartlands Hospital, Birmingham, BIR

Local Institution - 0351, Bristol, BST

Papworth Hospital NHS Foundation Trust, Cambridge, Cambridgeshire

NHS Tayside, Dundee, DND

NHS Lothian - Royal Infirmary of Edinburgh, Edinburgh, EDH

Guy's and St Thomas' NHS Foundation Trust - Royal Brompton Hospital, London, Greater London

Local Institution - 0365, Southampton, Hampshire

Local Institution - 0381, London, LND

Local Institution - 0422, Nottingham, Nottinghamshire

Oxford University Hospitals NHS Trust - Churchill Hospital, Oxford, Oxfordshire

Peterborough City Hospital, Peterborough, PTE

Local Institution - 0219, Exeter, South West

Local Institution - 0353, South Shields, STY

Leeds Teaching Hospitals NHS Trust, Leeds, West Yorkshire

Hull and East Yorkshire Hospitals NHS Trust - Castle Hill Hospital, Cottingham, Yorkshire And The Humber

University Hospitals Birmingham NHS Foundation Trust - New Queen Elizabeth Hospital Birmingham, Birmingham, Not set

Conditions: Progressive Pulmonary Fibrosis

Learn More ›

A Study to Evaluate the Efficacy and Safety of GDC-8264 in Preventing Cardiac Surgery-Associated Acute Kidney Injury (AKI) and Major Adverse Kidney Events (MAKE)

NCT06602453

Recruiting

The aim of this study is to evaluate the efficacy and safety of GDC-8264 compared with placebo in participants undergoing cardiac surgery who are determined to be at moderate to high risk of developing AKI and subsequent MAKE at 90 days after surgery (MAKE90). The study will be performed in two parts- Part 1 and Part 2.

Gender:

ALL

Ages:

40 years and above

Trial Updated:

07/28/2025

Locations: Ronald Reagan UCLA Medical Center, Los Angeles, California +30 locations

Ronald Reagan UCLA Medical Center, Los Angeles, California

University of Stanford Medical Center, Stanford, California

Yale School of Medicine Yale New Haven Hospital, New Haven, Connecticut

James A Haley Veteran Affairs Medical Center - NAVREF - PPDS, Tampa, Florida

Baystate Cardiac Surgery, Springfield, Massachusetts

Mayo Clinic - PPDS, Rochester, Minnesota

CHI Health Nebraska Heart, Lincoln, Nebraska

Columbia University Irving Medical Center, New York, New York

Duke University Medical Center, Durham, North Carolina

Atrium Health Wake Forest University School of Medicine - PPDS, Winston-Salem, North Carolina

University of Virginia Health System, Charlottesville, Virginia

Aurora St Lukes Medical Center, Milwaukee, Wisconsin

Gold Coast University Hospital, Southport, Queensland

Townsville Hospital, Townsville, Queensland

UZ Leuven, Leuven, Not set

Hopital de la Citadelle, Liege, Not set

Saint John Regional Hospital, Saint John, New Brunswick

Vseobecna fakultni nemocnice v Praze, Praha 2, Not set

Fakultni nemocnice v Motole, Praha 5, Not set

CHU Angers, Angers, Not set

APHP - Hopital de la Pitie Salpetriere, Paris, Not set

CHU de Reims, Reims, Not set

Herzzentrum Dresden GmbH Universitatsklinikum, Dresden, Not set

Severance Hospital Yonsei University Health System - PPDS, Seoul, Not set

Samsung Medical Center - PPDS, Seoul, Not set

Auckland City Hospital, Auckland, Not set

Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona

C.H. Regional Reina Sofia - PPDS, Cordoba, Not set

Hospital Universitario de La Princesa, Madrid, Not set

Royal Infirmary of Edinburgh, Edinburgh, Not set

Southampton General Hospital, Southampton, Not set

Conditions: Acute Kidney Injury

Learn More ›

A Study to Investigate Efficacy, Safety, and Tolerability of Remibrutinib Compared With Placebo in Adults With CINDU Inadequately Controlled by H1-antihistamines

NCT05976243

Recruiting

This is a Phase 3, parallel group, placebo-controlled, double-blind, confirmatory study in patients with CINDU, with an optional Open-label Extension (OLE). The purpose of the core period (52 weeks of treatment) of this study is to evaluate the efficacy, safety, and tolerability of remibrutinib (LOU064) vs. placebo in adults suffering from CINDU inadequately controlled by H1-antihistamines (H1-AHs). The purpose of the OLE period is to collect long-term efficacy, safety, and tolerability data o... Read More

Gender:

ALL

Ages:

Between 18 years and 100 years

Trial Updated:

07/28/2025

Locations: Allervie Clinical Research, Birmingham, Alabama +160 locations

Allervie Clinical Research, Birmingham, Alabama

Acuro Research Inc, Little Rock, Arkansas

Kern Research, Bakersfield, California

OC Allergy and Asthma Specialists, Huntington Beach, California

Antelope Valley Clinical Trials, Lancaster, California

Asthma and Allergy Associates P C, Colorado Springs, Colorado

Florida Ctr Allergy Asthma Research, Aventura, Florida

Finlay Medical Research, Greenacres City, Florida

Sarasota Clinical Research, Sarasota, Florida

Univ of South Florida Asthma Allergy and Immunology CRU, Tampa, Florida

AeroAllergy Research Laboratories of Savannah Inc, Savannah, Georgia

Treasure Valley Medical Research, Boise, Idaho

Endeavor Health, Glenview, Illinois

Asthma and Allergy Center of Chicago S C, River Forest, Illinois

The Indiana Clinical Trials Center, Plainfield, Indiana

Allergy and Asthma Specialist P S C, Owensboro, Kentucky

John Hopkins University, Baltimore, Maryland

Somnos Clinical Research, Lincoln, Nebraska

Toledo Institute of Clinical Research, Toledo, Ohio

Allergy Asthma and Clinical Research, Oklahoma City, Oklahoma

Allergy and Clinical Immunology Associates, Pittsburgh, Pennsylvania

National Allergy and Asthma Research LLS, North Charleston, South Carolina

PanAmerican Clinical Research, Brownsville, Texas

Asthma and Allergy Research Assoc, Dallas, Texas

Western Sky Medical Research, El Paso, Texas

RFSA Dermatology, San Antonio, Texas

STAAMP Research LLC, San Antonio, Texas

Complete Dermatology, Sugar Land, Texas

Allergy Associates of Utah, Sandy, Utah

Novartis Investigative Site, Caba, Buenos Aires

Novartis Investigative Site, Rosario, Santa Fe

Novartis Investigative Site, Buenos Aires, Not set

Novartis Investigative Site, Woolloongabba, Queensland

Novartis Investigative Site, Carlton, Victoria

Novartis Investigative Site, Melbourne, Victoria

Novartis Investigative Site, Alphaville Barueri, Sao Paulo

Novartis Investigative Site, Santo Andre, SP

Novartis Investigative Site, Sorocaba, SP

Novartis Investigative Site, Winnipeg, Manitoba

Novartis Investigative Site, Hamilton, Ontario

Novartis Investigative Site, Trois Rivieres, Quebec

Novartis Investigative Site, Fuzhou, Fujian

Novartis Investigative Site, Guangzhou, Guangdong

Novartis Investigative Site, Guangdong, Guangzhou

Novartis Investigative Site, Changsha, Hunan

Novartis Investigative Site, Wuxi, Jiangsu

Novartis Investigative Site, Chang Chun, Jilin

Novartis Investigative Site, Jinan, Shandong

Novartis Investigative Site, Chengdu, Sichuan

Novartis Investigative Site, Urumqi, Xinjiang

Novartis Investigative Site, Hangzhou, Zhejiang

Novartis Investigative Site, Yi Wu, Zhejiang

Novartis Investigative Site, Beijing, Not set

Novartis Investigative Site, Chongqing, Not set

Novartis Investigative Site, Jinan, Not set

Novartis Investigative Site, Nanjing, Not set

Novartis Investigative Site, Shanghai, Not set

Novartis Investigative Site, Tianjin, Not set

Novartis Investigative Site, Barranquilla, Atlantico

Novartis Investigative Site, Clermont Ferrand, Not set

Novartis Investigative Site, Grenoble, Not set

Novartis Investigative Site, Montpellier, Not set

Novartis Investigative Site, Nantes, Not set

Novartis Investigative Site, Paris, Not set

Novartis Investigative Site, Pierre Benite, Not set

Novartis Investigative Site, Rouen, Not set

Novartis Investigative Site, Toulouse, Not set

Novartis Investigative Site, Goettingen, Niedersachsen

Novartis Investigative Site, Berlin, Not set

Novartis Investigative Site, Dresden, Not set

Novartis Investigative Site, Luebeck, Not set

Novartis Investigative Site, Mainz, Not set

Novartis Investigative Site, Muenster, Not set

Novartis Investigative Site, Stade, Not set

Novartis Investigative Site, Tuebingen, Not set

Novartis Investigative Site, Hong Kong, Not set

Novartis Investigative Site, Debrecen, Hajdu Bihar

Novartis Investigative Site, Debrecen, Not set

Novartis Investigative Site, Szolnok, Not set

Novartis Investigative Site, Bangalore, Karnataka

Novartis Investigative Site, Mysore, Karnataka

Novartis Investigative Site, Nagpur, Maharashtra

Novartis Investigative Site, New Delhi, Not set

Novartis Investigative Site, Haifa, Not set

Novartis Investigative Site, Jerusalem, Not set

Novartis Investigative Site, Kfar Saba, Not set

Novartis Investigative Site, Ramat Gan, Not set

Novartis Investigative Site, Tel Aviv, Not set

Novartis Investigative Site, Ancona, AN

Novartis Investigative Site, Catania, CT

Novartis Investigative Site, Milano, MI

Novartis Investigative Site, Rozzano, MI

Novartis Investigative Site, Roma, RM

Novartis Investigative Site, Kitakyushu, Fukuoka

Novartis Investigative Site, Sapporo, Hokkaido

Novartis Investigative Site, Kamimashi-gun, Kumamoto

Novartis Investigative Site, Habikino city, Osaka

Novartis Investigative Site, Takatsuki, Osaka

Novartis Investigative Site, Ohtsu, Shiga

Novartis Investigative Site, Izumo-city, Shimane

Novartis Investigative Site, Shimotsuga Gun, Tochigi

Novartis Investigative Site, Bunkyo-ku, Tokyo

Novartis Investigative Site, Itabashi-ku, Tokyo

Novartis Investigative Site, Shinjuku Ku, Tokyo

Novartis Investigative Site, Tachikawa, Tokyo

Novartis Investigative Site, Hiroshima, Not set

Novartis Investigative Site, Kyoto, Not set

Novartis Investigative Site, Suwon si, Gyeonggi Do

Novartis Investigative Site, Seoul, Not set

Novartis Investigative Site, Muar, Johor

Novartis Investigative Site, Ipoh, Perak

Novartis Investigative Site, Georgetown, Pulau Pinang

Novartis Investigative Site, Kuala Lumpur, Wilayah Persekutuan

Novartis Investigative Site, Groningen, Not set

Novartis Investigative Site, Utrecht, Not set

Novartis Investigative Site, Bydgoszcz, Not set

Novartis Investigative Site, Olsztyn, Not set

Novartis Investigative Site, Rzeszow, Not set

Novartis Investigative Site, Warszawa, Not set

Novartis Investigative Site, Coimbra, Not set

Novartis Investigative Site, Lisboa, Not set

Novartis Investigative Site, Vila Nova De Gaia, Not set

Novartis Investigative Site, Bucharest, District 2

Novartis Investigative Site, Timisoara, Timis

Novartis Investigative Site, Brasov, Not set

Novartis Investigative Site, Cluj Napoca, Not set

Novartis Investigative Site, Singapore, Not set

Novartis Investigative Site, Bratislava, Not set

Novartis Investigative Site, Kezmarok, Not set

Novartis Investigative Site, Trnava, Not set

Novartis Investigative Site, Zilina, Not set

Novartis Investigative Site, Santiago de Compostela, A Coruna

Novartis Investigative Site, Granada, Andalucia

Novartis Investigative Site, Barcelona, Catalunya

Novartis Investigative Site, Mostoles, Madrid

Novartis Investigative Site, Alicante, Not set

Novartis Investigative Site, Cordoba, Not set

Novartis Investigative Site, Madrid, Not set

Novartis Investigative Site, Valencia, Not set

Novartis Investigative Site, Bangkok, Not set

Novartis Investigative Site, Chiang Mai, Not set

Novartis Investigative Site, Istanbul, Not set

Novartis Investigative Site, Sakarya, Not set

Novartis Investigative Site, Talas Kayseri, Not set

Novartis Investigative Site, Glasgow, Not set

Novartis Investigative Site, Oxford, Not set

Novartis Investigative Site, Hanoi, Not set

Novartis Investigative Site, Ho Chi Minh, Not set

Conditions: Chronic Inducible Urticaria

Learn More ›

ATI-045 Versus Placebo in Patients With Moderate-to-Severe Atopic Dermatitis

NCT07011706

Recruiting

This study evaluates ATI-045 versus placebo in patients with Moderate-to-Severe Atopic Dermatitis.

Gender:

ALL

Ages:

Between 18 years and 70 years

Trial Updated:

07/28/2025

Locations: Aclaris Study Site, Bryant, Arkansas +22 locations

Conditions: Atopic Dermatitis, Atopic, Dermatitis, AD, Eczema

Learn More ›

Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE

NCT06669754

Recruiting

This is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of once-daily orally administered deucrictibant extended-release tablet compared to placebo for prophylaxis to prevent angioedema attacks in participants aged ≥ 12 years with hereditary angioedema.

Gender:

ALL

Ages:

12 years and above

Trial Updated:

07/28/2025

Locations: Study Site, Little Rock, Arkansas +51 locations

Study Site, Little Rock, Arkansas

Study site, Santa Monica, California

Study site, Walnut Creek, California

Study Site, Wheaton, Maryland

Study Site, Saint Louis, Missouri

Study Site, Corrientes, Not set

Study Site, Sofia, Not set

Study Site, Edmonton, Not set

Study Site, Ottawa, Not set

Study Site, Grenoble, Not set

Study Site, Lille, Not set

Study Site, Berlin, Not set

Study Site, Frankfurt, Not set

Study Site, Hannover, Not set

Study Site, Hongkong, Not set

Study Site, Budapest, Not set

Study Site, Dublin, Not set

Study Site, Milan, Not set

Study Site, Padova, Not set

Study Site, Kawasaki, Not set

Study Site, Tokyo, Not set

Study Site, Daegu, Not set

Study Site, Seoul, Not set

Study Site, Suwon, Not set

Study Site, Auckland, Not set

Study Site, Kraków, Not set

Study Site, San Juan, Not set

Study Site, Sangeorgiu de Mures, Not set

Study Site, Singapore, Not set

Study Site, Martin, Not set

Study Site, Cape Town, Not set

Study Site, Barcelona, Not set

Study Site, Seville, Not set

Study Site, Basel, Not set

Study Site, Ankara, Not set

Study Site, Istanbul, Not set

Study Site, İzmir, Not set

Study site, London, England

Study Site, Birmingham, Not set

Study Site, Bristol, Not set

Study Site, Cambridge, Not set

Study Site, Frimley, Not set

Study Site, Leeds, Not set

Study Site, London, Not set

Study Site, Oxford, Not set

Study site, Plymouth, Not set

Study Site, Southampton, Not set

Conditions: Hereditary Angioedema (HAE)

Learn More ›

Pan-Canadian Lung Cancer Observational Study (PALEOS)

NCT04706754

Recruiting

A multicenter, ambispective observational study focusing on patients diagnosed with lung cancer in Canada identified after January 1, 2000 inclusive. This data will be combined with that from deceased patients identified.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/28/2025

Locations: Milena (Lynn) Vicente, Brampton, Ontario

Conditions: Lung Cancer

Learn More ›

Low-Dose Weekly vs High-Dose Cisplatin

NCT03649048

Recruiting

This study is a prospective open-label randomized clinical trial. Following informed consent eligible LASCCHN patients (n=100) planned for CRT will be stratified by tumor p16 status and then randomized in a 1:1 fashion to either concurrent HD cisplatin or concurrent weekly LD cisplatin.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/28/2025

Locations: Juravinski Cancer Centre, Hamilton, Ontario +2 locations

Conditions: Locally Advanced Head and Neck Squamous Cell Carcinoma

Learn More ›

MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

NCT06128629

Recruiting

To evaluate the efficacy and safety of a single dose of NTLA-2001 compared to placebo in participants with ATTR-CM.

Gender:

ALL

Ages:

Between 18 years and 90 years

Trial Updated:

07/28/2025

Locations: University of Arizona, Tucson, Arizona +126 locations

University of Arizona, Tucson, Arizona

Cedars-Sinai Medical Center, Los Angeles, California

Western Greater Los Angeles VA Medical Center, Los Angeles, California

Stanford University, Palo Alto, California

University of Colorado Denver, Denver, Colorado

Yale University School of Medicine, New Haven, Connecticut

MedStar Washington Hospital Center - MedStar Heart and Vascular Institute, Washington, District of Columbia

Mayo Clinic - Jacksonville, Jacksonville, Florida

Cleveland Clinic of Florida, Weston, Florida

Emory University School of Medicine, Atlanta, Georgia

Northwestern University, Chicago, Illinois

Indiana University Health, Indianapolis, Indiana

University of Kentucky Gill Heart Institute, Lexington, Kentucky

Johns Hopkins University, Baltimore, Maryland

Brigham and Women's Hospital, Boston, Massachusetts

Boston University School of Medicine, Boston, Massachusetts

University of Michigan, Ann Arbor, Michigan

Barbara Ann Karmanos Cancer Institute, Detroit, Michigan

Mayo Clinic, Rochester, Minnesota

St. Luke's Hospital, Kansas City, Missouri

New York University (NYU) School of Medicine - Langone Medical Center, New York, New York

Columbia University Medical Center, New York, New York

Duke University Medical Center, Durham, North Carolina

Cleveland Clinic, Cleveland, Ohio

Ohio Health Research Institute, Columbus, Ohio

Oregon Health and Science University (OHSU), Portland, Oregon

Penn Presbyterian Medical Center, Philadelphia, Pennsylvania

Allegheny General Hospital, Pittsburgh, Pennsylvania

University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania

Medical University of South Carolina, Charleston, South Carolina

University of Texas Southwestern Medical Center, Dallas, Texas

Baylor College of Medicine, Houston, Texas

Houston Methodist Hospital, Houston, Texas

Baylor Scott and White - The Heart Hospital Baylor Plano, Plano, Texas

INOVA Fairfax Hospital, Falls Church, Virginia

Virginia Commonwealth University - Department of Internal Medicine, Richmond, Virginia

Fundacion Favalro, Buenos Aires, Not set

Hospital Italiano de Buenos Aires, Buenos Aires, Not set

ICBA, Buenos Aires, Not set

Fundacion Favaloro, Ciudad Autonoma de Buenos Aire, Not set

Hospital Italiano de Buenos Aires, Ciudad Autonoma de Buenos Aire, Not set

Hospital Privado de Rosario, Rosario, Not set

The Canberra Hospital, Garran, Australian Capital Territory

Westmead Hospital, Westmead, New South Wales

Cairns Hospital, Cairns, Queensland

Eastern Health - Box Hill Hospital, Box Hill, Victoria

Fiona Stanley Hospital, Perth, Western Australia

Royal Adelaide Hospital, Adelaide, Not set

The Alfred Hospital, Melbourne, Not set

Princess Alexandra Hospital, Woolloongabba, Not set

Medizinische Universitaet Innsbruck, Innsbruck, Not set

Universitaesklinikum St. Poelten, St. Polten, Not set

Universite Libre de Bruxelles (ULB) - Hopital Erasme, Bruxelles, Not set

Antwerp University Hospital, Edegem, Not set

UZ Leuven, Leuven, Not set

Centre Hospitalier Regional de la Citadelle, Liège, Not set

Centro de Pesquisa NUPEC - Instituto Orizonti em Belo Horizonte, Belo Horizonte, Not set

Complexo Hospitalar de Niterói (CHN-DASA), Niterói, Not set

CAPED - Centro Avancado de Pesquisa, Ribeirão Preto, Not set

HCFMRP - Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto, Ribeirão Preto, Not set

Hospital Israelita Albert Einstein, São Paulo, Not set

Instituto Dante Pazzanese de Cardiologia, São Paulo, Not set

Instituto do Coracao (InCor) do Hospital das Clinicas da FMUSP, São Paulo, Not set

PSEG Centro de Pesquisa Clinica S.A., São Paulo, Not set

Alberta Health Services - University of Calgary, Calgary, Alberta

Vancouver Coastal Health Research Institute, Vancouver, British Columbia

University Health Network - Toronto General Hospital, Toronto, Ontario

McGill University Health Centre, Montréal, Quebec

Fakultni nemocnice u sv. Anny v Brne, Brno, Not set

Aarhus University Hospital, Aarhus, Not set

Rigshospitalet, Copenhagen, Not set

AP-HP Hopital Henri Mondor, Créteil, Not set

AP-HM - Hopital de la Timone, Marseille, Not set

AP-HP Hopital Bichat - Claude Bernard, Paris, Not set

CHU Rennes - Hopital Pontchaillou, Rennes, Not set

CHU de Toulouse - Hopital Rangueil, Toulouse, Not set

Charite Universitaetsmedizin Berlin, Berlin, Not set

Universitaetsklinikum Essen, Essen, Not set

Universitaetsklinikum Heidelberg, Heidelberg, Not set

Universitaetsklinikum Wuerzburg, Würzburg, Not set

Semmelweis Egyetem Belgyogyaszati es Hematologiai Klinika, Budapest, Not set

Rambam Health Care Campus, Haifa, Not set

Hadassah University Hospital, Ein Karem, Jerusalem, Not set

Sheba Medical Center, Tel HaShomer, Not set

IRCCS Azienda Ospedaliero-Universitaria di Bologna - Policlinico di Sant'Orsola, Bologna, Not set

Azienda Ospedaliero-Universitaria di Ferrara-Arcispedale Sant'Anna, Cona, Not set

Azienda Ospedaliero-Universitaria Careggi, Firenze, Not set

Ospedale Policlinico San Martino IRCCS, Genova, Not set

Fondazione IRCCS Policlinico San Matteo, Pavia, Not set

Fondazione Toscana Gabriele Monasterio per la Ricerca Medica, Pisa, Not set

Azienda sanitaria universitaria Giuliano Isontina (ASU GI) - Ospedale di Cattinara, Trieste, Not set

Kumamoto University Hospital, Kumamoto, Not set

National Cerebral and Cardiovascular Center, Osaka, Not set

The University of Tokyo Hospital, Tokyo, Not set

Toyama University Hospital, Toyama, Not set

Chonnam National University Hospital, Gwangju, Not set

Samsung Medical Center, Seoul, Not set

Seoul National University Hospital, Seoul, Not set

Severance Hospital, Yonsei University Health System, Seoul, Not set

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Ciudad de mexico, Not set

University Medical Center, Groningen, Not set

Erasmus MC, Rotterdam, Not set

Universitair Medisch Centrum Utrecht, Utrecht, Not set

New Zealand Clinical Research, Auckland, Not set

New Zealand Clinical Research, Christchurch, Not set

Oslo University Hospital - Rikshospitalet, Oslo, Not set

Centro Hospitalar Universitario de Lisboa Norte, Lisbon, Not set

Centro Hospitalar Universitario do Porto, Porto, Not set

National Heart Centre, Singapore, Not set

National University Hospital, Singapore, Not set

Hospital Universitari de Bellvitge, Barcelona, Not set

Hospital Universitario Vall d'Hebron, Barcelona, Not set

Hospital Universitario Puerta de Hierro, Majadahonda, Not set

Hospital Universitario Virgen de la Victoria, Málaga, Not set

Hospital Universitario Son Llatzer, Palma De Mallorca, Not set

Karolinska University Hospital, Stockholm, Not set

University Hospital of Umea, Umea, Not set

Far Eastern Memorial Hospital, New Taipei City, Not set

National Taiwan University Hospital, Taipei, Not set

Taipai Veterans General Hospital, Taipei, Not set

Synexus Midlands Clinical Research Centre, Birmingham, Not set

Synexus Wales Clinical Research Centre, Cardiff, Not set

Synexus Scotland Clinical Research Centre, Glasgow, Not set

Synexus Hexham Clinical Research Centre, Hexham, Not set

Synexus Merseyside Clinical Research Centre, Liverpool, Not set

Richmond Pharmacology, London, Not set

Synexus Manchester Clinical Research Centre, Manchester, Not set

Conditions: Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

Learn More ›

Canadian Medical Assessment of JINARC™ Outcomes Registry

NCT02925221

Recruiting

This study is part of the Health Canada approval requirement for JINARC™ (tolvaptan) and is an observational, non-interventional study (NIS) describing the impact of tolvaptan on ADPKD-related burden of illness as measured with a set of Patient Reported Outcome (PRO) Questionnaires. The study is also describing the time to renal replacement therapy (RRT), such as dialysis and transplantation, and the long-term mortality rate and causes (i.e. renal and hepatic), in ADPKD patients treated with JIN... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/28/2025

Locations: Not set, Edmonton, Alberta +5 locations

Conditions: Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Learn More ›

Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

NCT05781152

Recruiting

Crohn's disease (CD) is a condition that causes inflammation (swelling, redness) of the lining and wall of the small intestine, large intestine, or both. CD may be associated with abdominal cramps/pain, diarrhea, blood in the stool, weight loss, or delayed growth in children. While the exact cause of CD is not certain it is thought that the immune system located in the intestine reacts abnormally to the large number of bacteria contained there. The investigators think that diet, exposure to antibiotics early in life, and having a family history of CD puts people at increased risk for developing CD. In order to decrease the inflammation doctors use what is called biologic therapy with anti-TNF molecules that can be given through an intravenous or shots. TNF is a chemical made by white blood cells that is involved in inflammation. When this type of treatment is given early after diagnosis it is more effective than when it is given later. The investigators have learned that it is important to give the optimum (ideal) amount of this medicine guided by certain blood tests. The investigators also know that not everyone responds to this therapy but do not understand the reasons for this variability between people. The CAMEO study has been started to help understand what factors are important in determining whether a child with CD completely heals the inflammation after anti-TNF therapy. The investigators will do that by measuring certain markers of inflammation in the blood and stool and by looking at a person's genes (DNA) and how inflammation is controlled in the intestine. These inflammation tests will be done before, during, and after one year of anti-TNF therapy. The investigators will determine how much healing has taken place by comparing the results of the colonoscopy and a special type of MRI that are both done before anti-TNF and then again one year later. The goal in treating CD is to heal both the lining and the wall of the intestine. Children ages 6-17 years who are thought to have CD and are about to undergo their diagnostic colonoscopy are eligible to be enrolled. If they are found to indeed have CD and start an anti-TNF medicine within 6 months they can continue in the study. There are no increased risks of participating in this study beyond those normally associated with having CD and its treatment. By better understanding why the bowel does or does not heal, doctors will be better able to provide personalized care. Read Less

Gender:

ALL

Ages:

Between 6 years and 17 years

Trial Updated:

07/28/2025

Locations: Phoenix Children's Hospital, Phoenix, Arizona +25 locations

Phoenix Children's Hospital, Phoenix, Arizona

Cedars-Sinai, Los Angeles, California

Rady Children's Hospital - San Diego and University of California, San Diego, San Diego, California

UCSF Benioff Children's Hospitals, San Francisco, California

Connecticut Children's Medical Center, Hartford, Connecticut

Emory University, Atlanta, Georgia

Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana

The Johns Hopkins Children's Medical Center, Baltimore, Maryland

Boston Children's Hospital, Boston, Massachusetts

University of Michigan, Ann Arbor, Michigan

Goryeb Children's Hospital/Morristown Medical Center/Atlantic Children's Health, Morristown, New Jersey

Cohen Children's Medical Center of NY, Lake Success, New York

Columbia University Medical Center, New York, New York

Levine Children's, Charlotte, North Carolina

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

UH/Rainbow Babies and Children's Hospital, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania

Rhode Island Hospital, Providence, Rhode Island

Seattle Children's Hospital, Seattle, Washington

Medical College of Wisconsin, Milwaukee, Wisconsin

Stollery Children's Hospital, Edmonton, Alberta

Children's Hospital Western Ontario, London, Ontario

Children's Hospital of Eastern Ontario, Ottawa, Ontario

Toronto SickKids Hospital, Toronto, Ontario

Conditions: Crohn Disease

Learn More ›