The state of California currently has 41 active clinical trials seeking participants for Asthma research studies. These trials are conducted in various cities, including Los Angeles, San Francisco, San Diego and Sacramento.
PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma) Network Study
NCT04129931
Recruiting
The primary objective of this study is to evaluate several interventions given to participants with severe asthma. Interventions are administered in a crossover manner with 16-week treatment periods followed by 8 to 16 week washout.
Gender:
All
Ages:
12 years and above
Trial Updated:
05/16/2023
Locations: University of California Davis, Sacramento, California +3 locations
Conditions: Asthma
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Lung Function Outcomes Following Removal of Airway Mucus Plugs in Patients With Asthma (FOCUS)
NCT05748912
Recruiting
This is a single-center study that will evaluate the safety and tolerability of removal of mucus plugs by bronchoscopy in patients with asthma. This protocol will also plan for the analysis of the features of the mucus plugs removed.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/17/2023
Locations: UCSF Airway Clinical Research Center, San Francisco, California
Conditions: Asthma
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Blood Lymphocytes in Asthmatics Treated With Therapeutic Proteins
NCT04514926
Recruiting
This is an observational, clinic-based, single center study of 120 subjects. Participants will be comprised of patients seen in the outpatient faculty practice in ambulatory care at the UCSF Parnassus campus. Study investigators will enroll 20 healthy participants with no history of lung disease, 50 asthmatics who are newly prescribed therapeutic proteins for their asthma, and 50 asthmatics already being treated with therapeutic proteins for their asthma. Participants will be seen at 1 to 3 visi... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/09/2023
Locations: University of California, San Francisco, San Francisco, California
Conditions: Asthma, Therapeutic Proteins
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The Effect of NAC on Lung Function and CT Mucus Score
NCT03822637
Recruiting
This study evaluates 20% n-acetylcysteine (NAC) in the treatment of moderate-to-severe asthma that is complicated by mucus in the airway, as determined by CT imaging. The study is a crossover design, which means that half the study participants will get 20% NAC in the first 14-day treatment period and placebo in the next 14-day treatment period; and the other half will get placebo in the first 14-day treatment period and 20% NAC in the next 14-day treatment period.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/08/2023
Locations: UCSF Airway Clinical Research Center, San Francisco, California
Conditions: Asthma
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Tissue Immune Interaction in Nasal Polyposis
NCT04628442
Recruiting
This is a cross-sectional study of up to 100 subjects who are undergoing clinically indicated sinus procedures to treat chronic rhinosinusitis. Participants will be asked to donate leftover sino-nasal secretions, sino-nasal tissue and blood as well as undergo partial characterization. As optional extensions of the main study, participants may also undergo a biopsy of extra sino-nasal tissue for additional tissue analysis and/or a more detailed characterization visit performed in the UCSF Airway... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/08/2023
Locations: UCSF Airway Clinical Research Center, San Francisco, California
Conditions: Chronic Rhinosinusitis (Diagnosis), Chronic Rhinosinusitis With Nasal Polyps, Asthma
Register for Updates