There are currently 7 active clinical trials seeking participants for Renal Impairment research studies. The states with the highest number of trials for Renal Impairment participants are Florida, California, Minnesota and Texas.
A Phase I Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD5004
NCT06742762
Recruiting
This is a Phase I, multicentre, single-dose, non-randomised, open-label, parallel-group study to examine the PK, safety, and tolerability of AZD5004 in male and female participants with severe renal impairment and moderate renal impairment (optional) compared with male and female participants with normal renal function.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/26/2025
Locations: Research Site, Miami Lakes, Florida +2 locations
Conditions: Renal Impairment
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A Clinical Study of Enlicitide in Participants With Severe Renal Impairment (MK-0616-032)
NCT06643377
Recruiting
Researchers have designed a new study medicine called enlicitide decanoate as a new way to lower the amount of low-density lipoprotein cholesterol (LDL-C) in a person's blood. Enlicitide decanoate will be called "enlicitide" from this point forward, The purpose of this study is to learn what happens to enlicitide in a person's body over time (a pharmacokinetic (PK) study). Researchers will compare what happens to enlicitide in the body when it is given to people with severe renal impairment (mea... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
03/17/2025
Locations: Velocity Clinical Research, New Smyrna Beach ( Site 0003), Edgewater, Florida +4 locations
Conditions: Healthy, Renal Impairment
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A Study to Evaluate BMS-986278 in Participants With Normal Renal Function, Severe Renal Impairment, or End-Stage Renal Disease on Intermittent Hemodialysis
NCT06723535
Recruiting
The purpose of this study is to assess the effect of severe renal impairment (RI) and end-stage renal disease (ESRD) with intermittent hemodialysis (IHD) on the pharmacokinetics and safety of BMS-986278. This study plans to use a staged design based on RI severity.
Gender:
ALL
Ages:
Between 18 years and 84 years
Trial Updated:
03/11/2025
Locations: Clinical Pharmacology Of Miami, LLC, Miami, Florida +3 locations
Conditions: Kidney Failure, Chronic, Healthy Volunteers, Renal Impairment
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Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD6234
NCT06845813
Recruiting
This study will evaluate the pharmacokinetics (PK), safety, and tolerability of single subcutaneous dose of AZD6234 with end stage renal disease, severe, and possibly moderate and mild renal impairment in comparison to a matched healthy control group.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/05/2025
Locations: Research Site, Lake Forest, California +3 locations
Conditions: Renal Impairment
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Safety and Pharmacokinetics Study of MBX 2109 in Adult Subjects With Normal and Impaired Renal Function
NCT06496217
Recruiting
Evaluate the Safety and Pharmacokinetics of MBX 2109 in Adult Subjects with Normal and Impaired Renal Function
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
07/17/2024
Locations: MBX Biosciences Investigational Site, Miami, Florida +2 locations
Conditions: Renal Impairment
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A Study to Evaluate the Drug Levels of Mezigdomide in Adult Participants With Renal Impairment
NCT06318676
Recruiting
The purpose of this study is to evaluate the drug levels of mezigdomide in participants with renal impairment.
Gender:
ALL
Ages:
Between 18 years and 82 years
Trial Updated:
07/11/2024
Locations: PANAX, Miami Lakes, Florida +2 locations
Conditions: Renal Impairment
Register for Updates
A Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics and Safety of VIR-2218
NCT05844228
Recruiting
The rationale of this study is to evaluate the impact of renal function on the PK, safety, and tolerability of VIR-2218 in participants with normal renal function and participants with varying degrees of renal dysfunction who are otherwise medically stable
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
05/01/2024
Locations: Inland Empire Clinical Trials, Rialto, California +2 locations
Conditions: Renal Impairment
Register for Updates