There are currently 55 clinical trials in Downey, California looking for participants to engage in research studies. Trials are conducted at various facilities, including Kaiser Permanente Downey Medical Center, Southern California Permanente Medical Group, Rancho Los Amigos National Rehabilitation Center and Rancho Research Institute. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
A Trial of the Efficacy and Safety of CVL-865 as Adjunctive Therapy in the Treatment of Focal Onset Seizures
NCT04244175
Recruiting
The purpose of this study is to assess the efficacy, safety, and tolerability profile of CVL-865 as adjunctive treatment in participants with drug-resistant focal onset seizures.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
03/06/2024
Locations: Downey, California, Downey, California
Conditions: Seizures
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A Study to See if Memantine Protects the Brain During Radiation Therapy Treatment for Primary Central Nervous System Tumors
NCT04939597
Recruiting
This phase III trial compares memantine to usual treatment in treating patients with primary central nervous system tumors. Memantine may block receptors (parts of nerve cells) in the brain known to contribute to a decline in cognitive function. Giving memantine may make a difference in cognitive function (attention, memory, or other thought processes) in children and adolescents receiving brain radiation therapy to treat a primary central nervous system tumors.
Gender:
All
Ages:
Between 4 years and 17 years
Trial Updated:
02/27/2024
Locations: Kaiser Permanente Downey Medical Center, Downey, California
Conditions: Central Nervous System Carcinoma
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Project: Every Child for Younger Patients With Cancer
NCT02402244
Recruiting
This study gathers health information for the Project: Every Child for younger patients with cancer. Gathering health information over time from younger patients with cancer may help doctors find better methods of treatment and on-going care.
Gender:
All
Ages:
25 years and below
Trial Updated:
02/27/2024
Locations: Kaiser Permanente Downey Medical Center, Downey, California
Conditions: Central Nervous System Neoplasm, Childhood Immature Teratoma, Childhood Langerhans Cell Histiocytosis, Childhood Mature Teratoma, Congenital Mesoblastic Nephroma, Lymphoproliferative Disorder, Myeloproliferative Neoplasm, Stromal Neoplasm, Carcinoma In Situ, Malignant Solid Neoplasm, Desmoid Fibromatosis, Ganglioneuroma, Melanocytic Neoplasm, Neuroendocrine Neoplasm
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A Post-Market Study for Long-Term Effectiveness and Safety of the NTX100 for RLS
NCT06076499
Recruiting
Multi-center post-market, observational study to assess the long-term effectiveness and safety of the NTX100 TOMAC System for patients with Restless Legs Syndrome.
Gender:
All
Ages:
21 years and above
Trial Updated:
02/20/2024
Locations: Mark J Buchfuhrer, MD Office, Downey, California
Conditions: Restless Legs Syndrome
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Collecting and Storing Tissue From Young Patients With Cancer
NCT00898755
Recruiting
This laboratory study is collecting and storing tissue, blood, and bone marrow samples from young patients with cancer. Collecting and storing samples of tissue, blood, and bone marrow from patients with cancer to study in the laboratory may help doctors learn more about changes that may occur in DNA and identify biomarkers related to cancer.
Gender:
All
Ages:
21 years and below
Trial Updated:
01/29/2024
Locations: Kaiser Permanente Downey Medical Center, Downey, California
Conditions: Acute Lymphoblastic Leukemia, Rhabdomyosarcoma, Acute Myeloid Leukemia, Central Nervous System Neoplasm, Ewing Sarcoma, Germ Cell Tumor, Leukemia, Lymphoma, Malignant Neoplasm, Neuroblastoma, Osteosarcoma, Retinoblastoma, Rhabdoid Tumor, Soft Tissue Sarcoma
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Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC
NCT04140526
Recruiting
This is a First-in-Human Phase IA/IB/II open label dose escalation study of intravenous (IV) administration of ONC-392, a humanized anti-CTLA4 IgG1 monoclonal antibody, as single agent and in combination with pembrolizumab in participants with advanced or metastatic solid tumors and non-small cell lung cancers.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/12/2024
Locations: The Oncology Institute of Hope and Innovation, Downey, California
Conditions: Non Small Cell Lung Cancer, Advanced Solid Tumor, Metastatic Melanoma, Metastatic Head and Neck Carcinoma, Metastatic Renal Cell Carcinoma, Metastatic Colorectal Cancer, Sarcomas, Metastatic Prostate Cancer, Ovarian Cancer, Small Cell Lung Cancer, Metastatic Breast Cancer, Pancreas Cancer, Gastric Cancer, Esophageal Cancer, Gastroesophageal Junction Adenocarcinoma, Cervical Cancer, Adenoid Cystic Carcinoma, Salivary Gland Cancer, Urothelial Carcinoma
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Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy
NCT05626634
Recruiting
The objective of this study is to assess the long-term safety, tolerability, and efficacy of adjunctive therapy of LP352 in subjects with developmental and epileptic encephalopathies who completed participation in Study LP352-201.
Gender:
All
Ages:
Between 12 years and 65 years
Trial Updated:
12/19/2023
Locations: Rancho Los Amigos National Rehabilitation Center (RLANRC), Downey, California
Conditions: Developmental and Epileptic Encephalopathy, Dravet Syndrome, Lennox-Gastaut Syndrome
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Peer Support for Patients With Diabetic Foot Ulcers
NCT06004219
Recruiting
The objective of the study is to develop a peer support program that helps improve ulcer care in patients with a diabetic foot ulcer (DFU).Diabetes, peripheral arterial disease (PAD), foot ulceration, and subsequent amputation are unevenly patterned in terms of racial/ethnicity, socioeconomic status, health insurance, and geographic area. The project will identify opportunities to reduce health disparities among economically marginalized patients regarding DFU outcomes.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/04/2023
Locations: Rancho Los Amigos National Rehabilitation Center, Downey, California
Conditions: Diabetic Foot Ulcer, Diabetic Wound, Diabetes Mellitus, Type 2, Diabetic Foot, Diabetes Complications, Peripheral Neuropathy
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Comparing Different Rehabilitation Exercise Strategies for Improving Arm Recovery After Stroke
NCT05880940
Recruiting
The purpose of this research study is to measure the effect of participating in extra arm exercise in addition to standard rehabilitation exercises in the Acute Rehabilitation Unit. This study will compare two different ways to perform the extra arm exercise. The first is following a customized program of hand and arm exercises that will be developed for study participants by an experienced rehabilitation therapist. The second is moving a participants arm back and forth when they are sitting in... Read More
Gender:
All
Ages:
Between 18 years and 84 years
Trial Updated:
11/16/2023
Locations: Rancho Research Institute, Downey, California
Conditions: Stroke
Register for Updates
Reducing Blood Pressure in Patients With High Cardiovascular Risk in the Safety-Net
NCT05937685
Recruiting
BP-REACH is a study of a team-based (pharmacist and health coach) program for lowering blood pressure for people with a prior stroke or heart attack in the Los Angeles Department of Health Services public healthcare system. The goal of this clinical trial is to test if this team based program is better at helping people reduce their blood pressure than usual care for people with prior heart attack or stroke. The main questions it aims to answer are: Do people in the REACH BP program have lower... Read More
Gender:
All
Ages:
35 years and above
Trial Updated:
11/02/2023
Locations: Rancho Los Amigos National Rehabilitation Center, Downey, California
Conditions: Myocardial Infarction, Hypertension, Stroke
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Spinal COrd NeuromodulaTor by SpIneX and ScoNE to Treat NeurogeniC BladdEr - SCONE "CONTINENCE" Clinical Study
NCT05301335
Recruiting
The purpose of this study is to evaluate the effectiveness and safety of SCONE neuromodulation therapy after 12 weeks of therapy in comparison to inactive sham control in improving symptoms of Neurogenic Lower Urinary Tract Dysfunction
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
10/19/2023
Locations: Rancho Research Institute, Downey, California
Conditions: Neurogenic Bladder, Stroke, Multiple Sclerosis, Spinal Cord Injuries (Complete and Incomplete)
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FitMi AD Home Therapy for Individuals With MCI or Mild Dementia Due to Alzheimer's Disease
NCT05504811
Recruiting
This study will investigate the efficacy of a newly developed exercise device (FitMi AD) for individuals with mild cognitive impairment (MCI) or mild dementia due to Alzheimer's disease. FitMi AD uses embedded sensors that can track and record the patient's direction and degree of movement while performing exercises described on a computer.
Gender:
All
Ages:
50 years and above
Trial Updated:
09/12/2023
Locations: Rancho Research Institute, Inc, Downey, California
Conditions: Cognitive Dysfunction, Dementia, Mild
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