The city of Irvine, California, currently has 2 active clinical trials seeking participants for Depression research studies.
Positive Affect Treatment for Adolescents With Early Life Adversity
Recruiting
Youth exposed to early life adversity (ELA) are known to be at greater risk for depression and suicidality and account for almost half of the youth suffering from psychiatric diseases today. Youth exposed to ELA consistently report symptoms of anhedonia as well as dysregulated positive affect. The present project will test the efficacy of PAT in a sample of ELA-exposed adolescents in order to determine whether PAT increases positive affect, and subsequently symptoms of depression. For this pilot... Read More
Gender:
All
Ages:
Between 12 years and 16 years
Trial Updated:
02/25/2024
Locations: University of California Irvine, Irvine, California
Conditions: Depression
Microbiome, Anxiety and Cognitive Orientation Study
Recruiting
Mounting evidence shows that the gut microbiome plays an important role in communication within the gut-brain axis. However, the relationship between gut microbiota and their influence on anxiety is still not fully understood. Recent studies on mice found a specific microbe-produced molecule, 4-ethylphenyl sulfate (4EPS), can induce anxious behavior. 4EPS is produced by gut microbes in mice and humans. Research suggests higher 4EPS levels may strongly be associated with anxiety levels. However,... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/12/2022
Locations: Endominance Inc., Irvine, California
Conditions: Anxiety, Microbiome, Mood Disorders, Neurodegeneration, Depression