The city of Los Angeles, California, currently has 6 active clinical trials seeking participants for Healthy research studies.
Single Nuclei RNA-seq to Map Adipose Cellular Populations and Senescent Cells in Older Subjects
Recruiting
All participants will undergo baseline biopsies of subcutaneous abdominal adipose tissue for cellular/molecular profiling via snRNA-seq and metabolic/physiological assessments (insulin sensitivity, glucose tolerance, and β-cell function). Older obese participants will be randomized into three arms: lifestyle intervention (n=24), senolytics (n=24), or placebo (n=24).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/20/2025
Locations: Cedars Sinai Medical Center, Los Angeles, California
Conditions: Obesity, Healthy Lifestyle
Observational Metabolic Health Study
Recruiting
The rationale for this study is to observe the effect of a consumer-grade commercially available product called Mimio Biomimetic Cell Care on metabolic health in overweight individuals. Additionally, the study aims to observe the effects of the study product on hunger and satiety, as well as effects on cognitive function, sleep, stress, pain, mood, gastrointestinal symptoms and metabolic and inflammatory blood markers via activities that can successfully and effectively be completed in a home se... Read More
Gender:
ALL
Ages:
55 years and above
Trial Updated:
01/17/2025
Locations: People Science, Inc., Los Angeles, California
Conditions: Healthy
Collection of Immunology Specimens From Patients With Cancer or Blood Disorders, and Healthy Volunteers
Recruiting
This research trial collects and stores blood, tissue, and bone marrow specimens from patients with cancer or blood disorders, and healthy volunteers to study the immune system in a variety of different types of experiments, as well as associated clinical data as appropriate, focused on understanding mechanisms of immunotherapy.
Gender:
All
Ages:
19 years and above
Trial Updated:
05/22/2024
Locations: USC / Norris Comprehensive Cancer Center, Los Angeles, California
Conditions: Healthy Subject, Hematologic and Lymphocytic Disorder, Hematopoietic and Lymphoid Cell Neoplasm, Immune System Disorder, Malignant Neoplasm
MS-ResearchBiomarkerS
Recruiting
This study is being conducted to investigate risk factors for disability progression in Multiple Sclerosis and related disorders (MSRD). The primary goal is to assess whether combining information from visual assessment, blood markers, as well as historical and ongoing longitudinal MRIs of the brain, orbit (the part of the skull where eyes are located), and/or spinal cord can predict changes in quantitative disability measures related to MSRD and neurological disease.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/05/2024
Locations: Cedars-Sinai Medical Center, Los Angeles, California
Conditions: Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Primary Progressive, Multiple Sclerosis, Secondary Progressive, Clinically Isolated Syndrome, Radiologically Isolated Syndrome, Neuromyelitis Optica Spectrum Disorders, Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease, Neurologic Autoimmune Disease, Neurologic Disorder, Healthy Aging
Cardiac Magnetic Resonance Imaging (MRI) Normal Reference Control Group Testing
Recruiting
The purpose of this research is to understand how to apply cardiac magnetic resonance imaging (CMR) to women with small artery heart disease by looking at the CMRs of women without heart disease. The investigators will study 40 women with no heart disease to learn more about the usefulness of CMR. Women suffer more than men from this disorder of the small vessels compared to the large vessels. This results in delays in diagnosis, missed opportunities for treatment, and likely contributes to the... Read More
Gender:
Female
Ages:
Between 35 years and 65 years
Trial Updated:
08/30/2023
Locations: Cedars-Sinai Women's Heart Center, Los Angeles, California
Conditions: Healthy
Lower Extremity BFR-randomized Controlled Trial Healthy Volunteers
Recruiting
The purpose of this research is to determine the effects of low-load blood flow restriction (BFR) training compared to conventional strengthening using dynamic force plate and isometric force frame analyses in healthy subjects.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/10/2023
Locations: Cedar Sinai Kerlan jobe orthopedic institute, Los Angeles, California
Conditions: Healthy