There are currently 2033 clinical trials in Los Angeles, California looking for participants to engage in research studies. Trials are conducted at various facilities, including Cedars-Sinai Medical Center, USC Norris Comprehensive Cancer Center, Children's Hospital Los Angeles and University of California Los Angeles. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Analgesic and Subjective Effects of Terpenes
NCT04451863
Recruiting
The purpose of this research is to assess the analgesic and subjective effects of terpenes administered alone and in combination of THC.
Gender:
All
Ages:
Between 21 years and 55 years
Trial Updated:
11/29/2023
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Pain, Abuse, Drug
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A PiLot ClinicaL TrIal of ParicAlcitol for ChroNiC PancrEatitis
NCT05664880
Recruiting
The purpose of this pilot study to examine the feasibility and acceptability of paricalcitol in adults with Chronic Pancreatitis (CP).
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
11/28/2023
Locations: Marissa Podell, Los Angeles, California
Conditions: Chronic Pancreatitis
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A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE)
NCT04951219
Recruiting
A 52-Week, Multi-center, Open-label, Active Treatment Extension Study to Evaluate Safety and Tolerability of Once Daily, Oral Administration of Resmetirom (MGL-3196)
Gender:
All
Ages:
18 years and above
Trial Updated:
11/28/2023
Locations: Ruane Clinical Research Group, Los Angeles, California +2 locations
Conditions: Non-Alcoholic Fatty Liver Disease
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Testing a Self-management Intervention in HIV+ Asian Pacific Americans
NCT04353739
Recruiting
HIV infection rates are on a rapid rise within Asian Pacific Americans (APA) communities, with 80% of new infects being men. The purpose of this study is to adapt and evaluate the feasibility of a 4-session, 4-week family-informed self-management intervention protocol to promote health among APA men with HIV (APAMHIV). Family-informed self-management is a promising intervention to assist APAMHIV in securing family support and promoting health, and hence help address HIV epidemics in this underst... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
11/27/2023
Locations: APAIT, Los Angeles, California
Conditions: Self-management
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A Study of NKT2152, a HIF2α Inhibitor, in Patients With Advanced Clear Cell Renal Cell Carcinoma
NCT05119335
Recruiting
The goal of the Phase 1 portion is to identify the maximum tolerated dose (MTD) and/or the recommended doses for expansion (RDEs) of NKT2152. The Phase 2 portion will evaluate the efficacy of NKT2152 in ccRCC.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: UCLA, Los Angeles, California
Conditions: ccRCC, Clear Cell Renal Cell Carcinoma, Kidney Cancer, Kidney Neoplasms, Renal Cancer, Renal Neoplasms, Recurrent Renal Cell Carcinoma, Metastatic Renal Cell Carcinoma, Refractory Renal Cell Carcinoma, Advanced Renal Cell Carcinoma, Hypoxia, Renal Cell Carcinoma, Hypoxia Inducible Factor (HIF), HIF2α Inhibitor, Hypoxia Inducible Factor 2 Alpha (HIF-2 Alpha), Hypoxia Inducible Factor 2α (HIF-2α), Clear Cell
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Treatment With Endovascular Intervention for STroke Patients With Existing Disability
NCT05911568
Recruiting
TESTED will compare the risks and benefits of endovascular thrombectomy (EVT) to medical management (no EVT) in ischemic stroke patients who have a blockage in one of the large blood vessels in the brain and have a moderate-to-severe disability prior to their stroke.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: University of California at Los Angeles, Los Angeles, California
Conditions: Stroke, Stroke, Acute, Stroke, Ischemic
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Key Dimensions of PTSD and ED
NCT03778307
Recruiting
This study will test whether endothelial dysfunction could be the early subclinical mechanism by which posttraumatic stress disorder (PTSD) increases cardiovascular disease (CVD) risk, and whether posttraumatic fear-a key component of PTSD-or another PTSD dimension could be the target to offset that risk. The results of this study may help trauma-exposed individuals who are at risk of having CVD events.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: UCLA, Los Angeles, California
Conditions: Trauma, PTSD, Endothelial Dysfunction
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TVMR With the Innovalve System Trial - Early Feasibility Study
NCT04919980
Recruiting
Study to evaluate the safety and performance of the Innovalve mitral valve replacement system
Gender:
All
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: Cedars-Sinai, Los Angeles, California
Conditions: Mitral Valve Regurgitation (Degenerative or Functional)
Register for Updates
Secondhand Effects of Hookah (i.e., Waterpipe) Smoke and Aerosol
NCT04661683
Recruiting
In the United States, secondhand smoke is the third leading preventable cause of death. Flavored hookah (waterpipe) tobacco smoking, a highly social activity common in hookah bars, is a key source of SHS exposure. While smoke-free air laws have decreased exposure to secondhand smoke, the majority of laws do not include hookah smoking. Thus, as a social outlet for youth and young adults, hookah smoke exposure may harm non-smokers, including women of reproductive age or pregnant, hookah bar worker... Read More
Gender:
All
Ages:
Between 21 years and 49 years
Trial Updated:
11/27/2023
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Hookah Smoking, Vascular Stiffness, Vaping, Secondhand Aerosol
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Evaluation of SPH3127 in Patients With Mild-to-Moderate Ulcerative Colitis
NCT05019742
Recruiting
SPH3127-US-01 is a multi-center, randomized, double-blind, placebo-controlled study to evaluate the safety, pharmacokinetics, and preliminary efficacy of SPH3127 for the treatment of mild-to-moderate ulcerative colitis.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
11/24/2023
Locations: Southern California Research Institute Medical Group, Inc., Los Angeles, California
Conditions: Ulcerative Colitis
Register for Updates
Rates and Risk Factors of Contact Between the OTX-TIC Intracameral Ocular Implant and Corneal Endothelium
NCT05835141
Recruiting
To determine what proportion of patients have inferior angle recess dimensions that could accommodate the OTX-TIC, and what are risk factors for implant contact with the corneal endothelium.
Gender:
All
Ages:
40 years and above
Trial Updated:
11/22/2023
Locations: USC Roski Eye Institute, Los Angeles, California
Conditions: Corneal Endothelium
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Children's Bipolar Network Treatment Trial I
NCT05427123
Recruiting
This is a naturalistic treatment and follow-up study of youth with bipolar spectrum disorders (BSDs) across four US sites of The Childhood Bipolar Network (CBN). CBN sites have expertise in diagnosing, assessing, and treating BSDs in youth. The primary aims of this study are to (1) identify and reliably diagnose youth (ages 9 to 19 yrs) with full bipolar disorder (BD) and BSDs, and (2) examine predictors (e.g., mood instability, inflammatory marker C-reactive protein) of clinical outcome over a... Read More
Gender:
All
Ages:
Between 9 years and 19 years
Trial Updated:
11/22/2023
Locations: University of California, Los Angeles, Max Gray Child and Adolescent Mood Disorders Program (CHAMP), Los Angeles, California
Conditions: Bipolar Disorder, Bipolar I Disorder, Bipolar II Disorder, Other Specified Bipolar and Related Disorder, Mood Instability, Child Mental Disorder, Adolescent - Emotional Problem
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