There are currently 2033 clinical trials in Los Angeles, California looking for participants to engage in research studies. Trials are conducted at various facilities, including Cedars-Sinai Medical Center, USC Norris Comprehensive Cancer Center, Children's Hospital Los Angeles and University of California Los Angeles. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Genetic, Metabolic, and Growth Factor Repository for Cerebrovascular Disorders
NCT02910180
Recruiting
This study encompasses the maintenance and utilization of a repository of samples from patients with cerebrovascular disease and stroke. The types of tissue taken are blood, cerebrospinal fluid (CSF), tissue, and microdialysis samples. Future analysis of these samples can potentially help investigators to better categorize groups of patients, understand the underlying etiology of these pathologies, identify markers that are associated with favorable or poor outcomes, and track changes that occur... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/06/2023
Locations: Cedars-Sinai Medical Center, Los Angeles, California
Conditions: Cerebrovascular Diseases, Ischemic Stroke, Repository
Register for Updates
Whole-Heart Myocardial Blood Flow Quantification Using MRI
NCT03064295
Recruiting
This study hopes to provide significant technical improvement in a Myocardial Blood Flow (MBF) cardiac magnetic resonance (CMR) quantification technique to address challenges and technical limitations for MBF CMR. By developing and validating novel techniques to improve first-pass perfusion (FPP) cardiac MR, we propose to increase diagnostic accuracy by minimizing false positives and false negatives, allow for better evaluation and accurate quantification of total ischemic burden and reduce imag... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/06/2023
Locations: Cedars-Sinai Medical Center, Los Angeles, California
Conditions: Coronary Artery Disease, Coronary Microvascular Disease
Register for Updates
ZZ06 in Adult Patients With Advanced EGFR Positive Solid Tumor Malignancies
NCT04412616
Recruiting
This is a Phase 1, Multicenter, Open-label study to assess the safety, tolerability and preliminary efficacy of ZZ06 in participants with all Adult Patients with Advanced EGFR-positive Solid Tumor Malignancies who are not able to have current standard anti-tumor therapies. The purpose of this study is to determine the maximum tolerated dose (MTD) , to characterise the safety, pharmacokinetics (PK), immunogenicity, pharmacodynamics (PD) and anti-tumor activity of ZZ06 as a single agent in adult p... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/06/2023
Locations: Cedars Sinai Medical Center, Los Angeles, California
Conditions: Advanced EGFR Positive Solid Tumor
Register for Updates
EXCOR Active Driving System for the EXCOR Pediatric VAD IDE Study
NCT05610787
Recruiting
The purpose of this study is to evaluate the device performance and monitor the safety and effectiveness of the Berlin Heart EXCOR Active Driving System while being used with the approved EXCOR Pediatric Ventricular Assist Device. EXCOR Active Driving System is intended for use with the approved EXCOR Pediatric VAD. The EXCOR Pediatric VAD is intended to provide mechanical circulatory support as a bridge to cardiac transplantation for pediatric patients. Pediatric candidates with severe isolat... Read More
Gender:
All
Ages:
21 years and below
Trial Updated:
02/06/2023
Locations: Children's Hospital of Los Angeles, Los Angeles, California
Conditions: Heart Failure, Transplant; Failure, Heart, Congenital Heart Disease
Register for Updates
Pituitary Tumor Surveillance: Pathogenic Correlation
NCT00599092
Recruiting
The purpose of this study is to observe predictors of pituitary tumor recurrence and markers of persistent disease activity in patients harboring pituitary mass lesions of all types.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/06/2023
Locations: Cedars-Sinai Medical Center, Pituitary Center, Los Angeles, California
Conditions: Pituitary Tumor
Register for Updates
Artificial Intelligence Guided Echocardiographic Screening of Rare Diseases (EchoNet-Screening)
NCT05139797
Recruiting
Despite rapidly advancing developments in targeted therapeutics and genetic sequencing, persistent limits in the accuracy and throughput of clinical phenotyping has led to a widening gap between the potential and the actual benefits realized by precision medicine. Recent advances in machine learning and image processing techniques have shown that machine learning models can identify features unrecognized by human experts and more precisely/accurately assess common measurements made in clinical... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/06/2023
Locations: Cedars-Sinai Medical Centre (Los Angeles), Los Angeles, California
Conditions: Cardiac Amyloidosis
Register for Updates
Allograft Adipose Injectable for Vocal Fold Paralysis
NCT04700566
Recruiting
Renuva is allograft adipose matrix commonly used as a filler in cosmetic procedures. The investigators are studying this material as an injectable in the vocal fold to treat glottic insufficiency. Currently, many products can be used as an injectable in the vocal fold to correct glottic insufficiency such as carbomethycellulose, hyaluronic acid, collagen derivatives and calcium hydroxyapatite amongst others. An ideal injectable would not impair the fibroelastic property of the vocal fold tissu... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/02/2023
Locations: University of Southern California, Los Angeles, California
Conditions: Vocal Fold Palsy
Register for Updates
A Study of Navicixizumab Monotherapy or in Combination in Patients With Select Advanced Solid Tumors
NCT05453825
Recruiting
This is a study of navicixizumab monotherapy or in combination with paclitaxel or irinotecan in patients with advanced cancer. Patients will be enrolled into one of the following cancer cohorts: Cohort A: CRC Cohort B: Gastric and GEJ cancer Cohort C: TNBC Cohort D: Platinum-resistant/refractory epithelial ovarian, primary peritoneal, or fallopian tube cancer (ovarian cancer)
Gender:
All
Ages:
18 years and above
Trial Updated:
01/30/2023
Locations: Keck Medicine of USC, Los Angeles, California
Conditions: Colorectal Cancer, Triple Negative Breast Cancer, Gastric Cancer, Ovarian Cancer
Register for Updates
Transcranial Magnetic Stimulation and Tobacco Use Disorder
NCT03827265
Recruiting
The purpose of this study is to determine if brain stimulation using repetitive transcranial magnetic stimulation (rTMS) directed at different parts of the brain can decrease feelings of cigarette craving and symptoms of cigarette withdrawal, and also if men and women have different responses to rTMS. Participants will visit the University of California, Los Angeles (UCLA) five times: First, for in-person screening, then for four rTMS sessions, four three different brain regions. Everyone in th... Read More
Gender:
All
Ages:
Between 18 years and 45 years
Trial Updated:
01/27/2023
Locations: Semel Institute of Neuroscience, Los Angeles, California
Conditions: Tobacco Use Disorder
Register for Updates
Open Label Study for the Use of Transcranial Ultrasound Treatment of Tremor
NCT05475340
Recruiting
The purpose of this Phase I open label study is to evaluate longer term tolerability and potential effectiveness of transcranial ultrasound in people with tremor as a results of Parkinson's Disease or Essential Tremor.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
01/25/2023
Locations: Neurological Associates of West Los Angeles, Los Angeles, California
Conditions: Tremor, Parkinson Disease, Essential Tremor
Register for Updates
A Study of Evorpacept (ALX148) in Patients With Advanced HER2+ Gastric Cancer (ASPEN-06)
NCT05002127
Recruiting
A Phase 2/3 Study of Evorpacept (ALX148) in Combination With Trastuzumab, Ramucirumab, and Paclitaxel in Patients With Advanced HER2-overexpressing gastric/GEJ adenocarcinoma.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/23/2023
Locations: University of California Los Angeles, Los Angeles, California
Conditions: Gastric Cancer, Gastroesophageal Junction Adenocarcinoma, Gastric Adenocarcinoma
Register for Updates
Real-World Experience - Barostim™ Advancing the Level of Clinical Evidence (REBALANCE Registry)
NCT04502316
Recruiting
The purpose of this registry is to develop valid scientific evidence of the safety and benefit of Barostim Therapy in the commercial setting in patients with heart failure with reduced ejection fraction (HFrEF) that were recently implanted with the Barostim System.
Gender:
All
Ages:
All
Trial Updated:
01/21/2023
Locations: University of Southern California, Los Angeles, California
Conditions: Heart Failure
Register for Updates