The city of San Diego, California, currently has 17 active clinical trials seeking participants for Depression research studies.
Combined Transcranial Magnetic Stimulation and Therapy for mTBI Related Headaches
NCT05176392
Recruiting
This study will assess the combined effectiveness of repetitive transcranial magnetic stimulation (rTMS) and telehealth based therapy in helping manage mild traumatic brain injury (mTBI) related headaches. The investigators hypothesize that active rTMS combined with telehealth therapy will provide marked reduction in mTBI related headaches and symptoms in comparison to their placebo counterparts.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
08/07/2023
Locations: VA San Diego Healthcare System, San Diego, California
Conditions: TBI (Traumatic Brain Injury), Headache, Depression
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Meditation Accelerated Brain Stimulation for Depression
NCT04586699
Recruiting
Repetitive Transcranial magnetic stimulation (rTMS) is an FDA-approved treatment for depression that involves brief magnetic stimulation pulses on the dorsolateral prefrontal cortex (DLPFC) brain region. The ultimate goal of this treatment is to increase excitability and long-term plasticity in DLPFC, a brain region shown to be hypo-active in depression. Unfortunately, rTMS only has low to moderate efficacy; remission rates for patients range from ~15-30% in large randomized controlled trials. T... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/02/2023
Locations: Neuromodulation Clinic Veterans Affairs San Diego, San Diego, California +1 locations
Conditions: Depression
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Study to Compare the Use of a Behavioral Health App Versus Care as Usual for 16-22 Year Olds With Depression
NCT05159713
Recruiting
Randomized Controlled Trial comparing a coach-enhanced digital cognitive behavioral intervention (d-CBI) (RxWell) + treatment as usual (TAU) versus TAU alone for moderate depression as determined by Patient Health Questionnaire (PHQ-9) threshold as part of routine pediatric care. The study will be completed in pediatric practices with embedded behavioral therapists across 3 institutions (Children's Hospital of Pittsburgh, Boston Children's Hospital, Rady Children's Hospital, San Diego).
Gender:
All
Ages:
Between 16 years and 22 years
Trial Updated:
06/02/2023
Locations: Rady Children's Hospital - San Diego, San Diego, California
Conditions: Depression
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Low-Dose Intravenous Ketamine for Adolescents With Depression and Suicidal Ideation in the Emergency Department
NCT05217706
Recruiting
The goal of this study is to test whether a single low-dose of IV ketamine given in the emergency department to adolescents with treatment-resistant depression and suicidal ideation can reduce depression symptoms and suicidal thoughts compared to placebo. Participants will complete depression scales at baseline, and 1 hour, 3 hours, 1 day, 3 days, and 7 days after receiving the treatment.
Gender:
All
Ages:
Between 12 years and 18 years
Trial Updated:
02/15/2023
Locations: Rady Children's Hospital San Diego, San Diego, California
Conditions: Depression, Suicidal Ideation
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Biofeedback for Psoriasis
NCT05506644
Recruiting
We are conducting a proof-of-concept trial to study the impact of HRV-biofeedback, a mind-body technique designed to improve stress resilience, on the quality of life, mood, and clinical skin severity of patients with psoriasis.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/16/2022
Locations: Bastyr University Clinic, San Diego, California
Conditions: Psoriasis, Psoriasis Vulgaris, Psychophysiological Disorder, Anxiety, Depression, Psychological Stress, Physiological Stress, Quality of Life, Skin Disorder, Skin Diseases
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