The city of Santa Monica, California, currently has 4 active clinical trials seeking participants for Osteoarthritis research studies.
Conventional Instrumentation, Computer Navigation, and Robotic Assistance Techniques in TKA
Recruiting
Knee osteoarthritis is a debilitating disease that can cause severe knee pain and significant limitations to patients' activities of daily living. Total knee arthroplasty (TKA), also known as knee replacement surgery, is a well-established and successful procedure for treatment of end-stage knee osteoarthritis. Over the years, TKA surgical techniques and implant technology have improved, resulting in better patient outcomes and implant survivorship. Despite continuous improvements being made to... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: UCLA Santa Monica Medical Center, Santa Monica, California
Conditions: Knee Osteoarthritis
The Effect of Adipose-Derived Stem Cells for Knee Osteoarthritis
Recruiting
The purpose of this study is to compare the clinical and functional outcomes of patients with mild to moderate arthroscopically confirmed osteoarthritis between the following two groups: Partial fat pad harvest with Adipose-Derived Stem Cell (ADSC) transplantation with standard arthroscopic treatment consisting of: partial meniscectomy, cartilage stabilization, loose body removal and selective synovectomy. Standard arthroscopic treatment (above) without cell transplant.
Gender:
All
Ages:
Between 35 years and 70 years
Trial Updated:
04/24/2024
Locations: Kerlan Jobe Orthopedic Institute, Santa Monica, California
Conditions: Knee Osteoarthritis
A Phase 2b/3a Study to Evaluate the Efficacy and Safety of JointStem in Patients Diagnosed as Knee Osteoarthritis
Recruiting
This study is a double-blind, randomized, placebo controlled, multi-center, superiority study to evaluate the efficacy and safety of JointStem, autologous adipose tissue derived mesenchymal stem cells (AdMSC), in patients diagnosed as knee osteoarthritis. Following a 2-week screening period, approximately 140 subjects will be randomly assigned into one of the following two arms in a 1:1 ratio (1 JointStem : 1 Placebo). After each subject completes 48-Weeks visit (Visit 8) and the data management... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/07/2023
Locations: Source Healthcare, Santa Monica, California
Conditions: Osteoarthritis, Knee
Genicular Artery Embolization Vs Observation for Symptomatic Knee Osteoarthritis
Recruiting
The purpose of this clinical trial is to determine whether genicular artery embolization (GAE) is an effective way to treat knee pain from osteoarthritis. Pain from arthritis is often due to underlying inflammation in the joint. The inflammation is associated with increased abnormal blood flow going to the specific area of pain. If the investigator can reduce the blood flow, the inflammation can be reduced and the pain can be controlled. The GAE procedure is an experimental procedure to decreas... Read More
Gender:
All
Ages:
Between 40 years and 79 years
Trial Updated:
08/29/2023
Locations: UCLA Santa Monica Hospital, Santa Monica, California
Conditions: Knee Osteoarthritis, Degenerative Joint Disease of Knee