The state of Colorado currently has 19 active clinical trials seeking participants for Multiple Sclerosis research studies. These trials are conducted in various cities, including Denver, Aurora, Colorado Springs and Englewood.
Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)
Recruiting
To compare the efficacy and safety of remibrutinib versus teriflunomide in patients with relapsing multiple sclerosis (RMS)
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
02/28/2025
Locations: Mountain Neuro Research Center PC, Basalt, Colorado +1 locations
Conditions: Relapsing Multiple Sclerosis
Study to Evaluate Efficacy of a Modified Regimen of Ublituximab
Recruiting
The primary purpose of this phase 3b study is to assess the efficacy of a modified regimen of ublituximab as measured by T1 Gadolinium (Gd)-enhancing lesions.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
02/27/2025
Locations: TG Investigational Site, Fort Collins, Colorado
Conditions: Relapsing Multiple Sclerosis
Best Available Therapy Versus Autologous Hematopoetic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)
Recruiting
This is a multi-center prospective rater-masked (blinded) randomized controlled trial of 156 participants, comparing the treatment strategy of Autologous Hematopoietic Stem Cell Transplantation (AHSCT) to the treatment strategy of Best Available Therapy (BAT) for treatment-resistant relapsing multiple sclerosis (MS). Participants will be randomized at a 1 to 1 (1:1) ratio. All participants will be followed for 72 months after randomization (Day 0, Visit 0).
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
12/09/2024
Locations: Rocky Mountain Multiple Sclerosis Center, University of Colorado School of Medicine, Aurora, Colorado
Conditions: Relapsing Multiple Sclerosis, Relapsing Remitting Multiple Sclerosis, Secondary Progressive Multiple Sclerosis
Reducing Fatigue in People With Multiple Sclerosis by Treatment With TENS
Recruiting
The objective of the randomized, sham-controlled trial will be to evaluate the effectiveness of treatment with transcutaneous electrical nerve stimulation (TENS) at reducing the level of fatigue experienced by people with MS.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/05/2024
Locations: University of Colorado, Boulder, Colorado
Conditions: Multiple Sclerosis
Prospective Evaluation of Sequencing From antiCD-20 Therapies to Ozanimod
Recruiting
A multi-center pilot study to evaluate safety and efficacy of ozanimod as de-escalation therapy in clinically stable MS patients previously treated with anti-CD20 therapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/06/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Relapsing Multiple Sclerosis
Acute Optic Neuritis Network: an International Study That Invesitages Subjects With a First-ever Episode of Acute Inflammation of the Optic Nerve
Recruiting
The goal of this observational study is to longitudinally investigating subjects with inaugural acute optic neuritis (ON). The main questions it aims to answer are: * Does the time to corticosteroid treatment affect the visual outcome at 6 months in subjects with acute multiple sclerosis (MS)-, aquaporin 4-IgG positive (AQP4-IgG+) and myelin-oligodendrocyte-glycoprotein-IgG positive (MOG-IgG+) ON? * How differ clinical, structural, and laboratory biomarkers in subjects with acute ON, including... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/31/2022
Locations: University of Colorado School of Medicine, Aurora, Colorado
Conditions: Demyelinating Diseases, Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorder Attack, Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease, Optic Neuritis
Home Based Infusions for Ocrelizumab
Recruiting
The goal is to assess the safety and effectiveness of home ocrelizumab infusion.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
06/08/2021
Locations: Amerita, Centennial, Colorado
Conditions: Multiple Sclerosis