The state of Colorado currently has 19 active clinical trials seeking participants for Osteoarthritis research studies. These trials are conducted in various cities, including Denver, Aurora, Colorado Springs and Englewood.
Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)
NCT05787821
Recruiting
The main objective of the study is to evaluate the safety, performance and clinical benefits of the Persona implant and its instrumentation in primary total knee arthroplasty
Gender:
All
Ages:
18 years and above
Trial Updated:
06/18/2024
Locations: Denver Hip & Knee, Inc., Parker, Colorado
Conditions: Knee Pain Chronic, Osteoarthritis, Knee, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee, Avascular Necrosis
Register for Updates
A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight
NCT05929066
Recruiting
The purpose of this study is to evaluate the efficacy and safety of retatrutide in participants who have obesity or overweight (J1I-MC-GZBJ master protocol) including subsets of participants who have knee osteoarthritis (OA) (J1I-MC-GOA1) or who have obstructive sleep apnea (OSA) (J1I-MC-GSA1). This study will last about 89 weeks and will include up to 24 visits.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/17/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Obesity, Overweight, Knee Pain Chronic, Knee Osteoarthritis, Obstructive Sleep Apnea
Register for Updates
Study of Efficacy, Safety and Tolerability of DFV890 in Patients With Knee Osteoarthritis
NCT04886258
Recruiting
This is a double-blinded, two-arm, phase II study to assess efficacy, safety and tolerability of DFV890 in participants with symptomatic knee osteoarthritis. The study includes a screening period, a treatment period and a follow-up period. At most, the study duration is 21 weeks.
Gender:
All
Ages:
Between 50 years and 80 years
Trial Updated:
06/03/2024
Locations: Skylight Health Res Inc Color Spr Research, Colorado Springs, Colorado
Conditions: Symptomatic Knee Osteoarthritis
Register for Updates
Zimmer Biomet Shoulder Arthroplasty PMCF
NCT04984291
Recruiting
The objectives of this study are to confirm the safety, performance, and clinical benefits of Zimmer Biomet Shoulder Arthroplasty Systems and its instrumentation in primary or revision shoulder arthroplasty. These objectives will be assessed using standard scoring systems, radiographic evidence, and adverse event records. Safety of the system will be assessed by monitoring the frequency an incidence of adverse events.
Gender:
All
Ages:
20 years and above
Trial Updated:
05/09/2024
Locations: Panorama Orthopaedic and Spine Center, Golden, Colorado
Conditions: Shoulder Fractures, Shoulder Arthritis, Shoulder Osteoarthritis, Shoulder Deformity, Shoulder Injuries, Shoulder Pain
Register for Updates
AETOS Shoulder System
NCT06319911
Recruiting
The goal of this study is to confirm the safety and performance of the AETOS Shoulder System for USA adoption. This is a prospective, open, adaptive, non-comparative, multi-centre investigation enrolling a maximum of 220 subjects in 2 cohorts (anatomic and reverse) at up to 15 sites. No intra-study comparator group will be included, and there will be no randomization
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: Western Orthopaedics, Denver, Colorado
Conditions: Shoulder Osteoarthritis, Shoulder Arthritis
Register for Updates
The Effect of Adipose-Derived Stem Cells for Knee Osteoarthritis
NCT03014401
Recruiting
The purpose of this study is to compare the clinical and functional outcomes of patients with mild to moderate arthroscopically confirmed osteoarthritis between the following two groups: Partial fat pad harvest with Adipose-Derived Stem Cell (ADSC) transplantation with standard arthroscopic treatment consisting of: partial meniscectomy, cartilage stabilization, loose body removal and selective synovectomy. Standard arthroscopic treatment (above) without cell transplant.
Gender:
All
Ages:
Between 35 years and 70 years
Trial Updated:
04/24/2024
Locations: UC Health Steadman Hawkins Clinic - Denver Inverness, Denver, Colorado
Conditions: Knee Osteoarthritis
Register for Updates
Restoration Anatomic Acetabular Shell Revision Study
NCT05591859
Recruiting
This study will be a non-randomized, ambidirectional (retrospective and prospective) study where all subjects will be followed prospectively. The study will evaluate the survivorship of the RAS acetabular component in a previously failed total hip arthroplasty (THA) in a consecutive series of subjects who meet the eligibility criteria.
Gender:
All
Ages:
All
Trial Updated:
03/20/2024
Locations: Regents of the University of Colorado, Denver, Colorado
Conditions: Arthropathy, Hip Arthropathy, Hip Osteoarthritis
Register for Updates
GAE Using Embosphere Microspheres vs Corticosteroid Injections for Treatment of Symptomatic Knee OA
NCT05818150
Recruiting
This multicenter, prospective, interventional trial is designed to assess the outcome of subjects with symptomatic knee osteoarthritis (OA) that are randomized to treatment with either genicular artery embolization (GAE) using Embosphere Microspheres or steroid injection over a period of 24 months.
Gender:
All
Ages:
21 years and above
Trial Updated:
03/15/2024
Locations: ECCO Medical, Lone Tree, Colorado
Conditions: Knee Osteoarthritis
Register for Updates
A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis Pain
NCT04504812
Recruiting
There is an urgent public health need to reduce reliance on opioids for effective long-term pain management, particularly in knee osteoarthritis (KOA). This effectiveness trial will compare commonly recommended treatments to reduce pain and functional limitations in KOA.These results will lead to improved patient selection for treatment and inform evidence based guidelines by offering well-tested, effective, non-surgical alternatives.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/07/2024
Locations: University of Colorado, Aurora, Colorado
Conditions: Knee Osteoarthritis
Register for Updates
Cemented vs Cementless Persona Keel RCT
NCT05630053
Recruiting
The main objective of this study is to evaluate the safety, performance, and clinical benefits of the Persona Keel cementless and cemented knee.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Centura Health, Westminster, Colorado
Conditions: Knee Pain Chronic, Rheumatoid Arthritis, Osteoarthritis, Traumatic Arthritis, Polyarthritis, Avascular Necrosis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee
Register for Updates
Exactech Shoulder Post Market Clinical Follow-up Study
NCT05603728
Recruiting
The objective of this study is to collect and evaluate long-term clinical and radiographic outcomes data in order to better understand the safety and performance of the shoulder arthroplasty over time. This study will follow subjects long-term for a minimum of 10-years, without an early-term restriction on the amount of time they will be followed.
Gender:
All
Ages:
21 years and above
Trial Updated:
02/23/2024
Locations: Western Orthopaedics, Denver, Colorado +1 locations
Conditions: Osteo Arthritis Shoulders, Osteonecrosis, Rotator Cuff Tears, Rotator Cuff Tear Arthropathy, Ankylosing Spondylitis, Post-traumatic Osteoarthritis, Rheumatoid Arthritis, Fracture, Infections
Register for Updates
Exactech Humeral Reconstruction Prosthesis of Shoulder Arthroplasty PMCF (HRP)
NCT05615246
Recruiting
The objective of this study is to collect and evaluate long-term clinical outcomes data in order to better understand the safety and performance of the Equinoxe Humeral Reconstruction Prosthesis in shoulder arthroplasty over time. This study will follow subjects for a period of up to 10 years post-surgery.
Gender:
All
Ages:
21 years and above
Trial Updated:
02/23/2024
Locations: Western Orthopaedics Research and Education Foundation, Denver, Colorado
Conditions: Osteoarthritis Shoulder, Rheumatoid Arthritis, Oncology
Register for Updates