GLP-1 Medications for Weight Loss Now Available!

The state of Colorado currently has 5 active clinical trials seeking participants for Weight Loss research studies. These trials are conducted in various cities, including Denver, Aurora, Colorado Springs and Englewood.
VK2735 for Weight Management Type 2 Diabetes Phase 3 (VANQUISH 2)
NCT07104383
Recruiting
This is a phase 3, multicenter, 78-week randomized, double-blind, placebo-controlled, parallel arm study that will evaluate the weight loss efficacy as well as safety, tolerability, pharmacodynamic effects, and pharmacokinetics of VK2735 in adults with Type 2 Diabetes who are obese or overweight
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/12/2025
Locations: Viking Clinical Site #2119, Denver, Colorado
Conditions: Weight Loss
Register for Updates
VK2735 for Weight Management Phase 3
NCT07104500
Recruiting
This is a phase 3, multicenter, 78-week randomized, double-blind, placebo-controlled, parallel arm study that will evaluate the weight loss efficacy as well as safety, tolerability, pharmacodynamic effects, and pharmacokinetics of VK2735 in adults who are obese (BMI ≥30 kg/m2) or overweight (BMI ≥27 kg/m2) with one or more weight related comorbid condition without Type 2 Diabetes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/12/2025
Locations: Viking Clinical Site #1119, Denver, Colorado
Conditions: Weight Loss
Register for Updates
Physiologic Response to Bariatric Surgery and the Impact of Adjunct Semaglutide in Adolescents
NCT06575738
Recruiting
The study plans to learn more about what happens to the body after bariatric surgery in people 12 to 24 years old. The study aims to understand why people respond differently to bariatric surgery and how to define success beyond weight loss alone. The study also plans to learn more about whether a medication (semaglutide) can help people 12 to 24 years old who, between 1 and 2 years after bariatric surgery, have not lost as much weight as expected.
Gender:
ALL
Ages:
Between 12 years and 24 years
Trial Updated:
02/24/2025
Locations: Childrens Hospital Colorado, Aurora, Colorado
Conditions: Obesity, Adolescent Obesity, Body-Weight Trajectory, Weight Loss Trajectory, Bariatric Surgery, Anti-obesity Agents
Register for Updates
Adipocyte-Derived Extracellular Vesicles, Weight Loss, and Endothelial Function
NCT06776081
Recruiting
Changes in adipose tissue biology are now recognized as a key factor underlying the increased risk of metabolic and cardiovascular disease with obesity. Clinical interest in adipocyte-derived extracellular vesicles (Ad-EVs) has intensified due to their potential as circulating biomarkers of adipose tissue health and systemic messengers, regulators and mediators of cardiometabolic health and disease with obesity. The investigators hypothesize that elevated Ad-EVs in adults with obesity will be n... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
01/09/2025
Locations: University of Colorado Boulder Clinical and Translational Research Center (CTRC), Boulder, Colorado
Conditions: Obesity, Weight Loss
Register for Updates
International Weight Control Registry
NCT04907396
Recruiting
The IWCR is a global scientific study aimed at better understanding the opportunities and barriers for reducing the prevalence of obesity by collecting information from people who have experience with weight management in their everyday lives. The investigators seek to gather information on a wide range of weight management experiences, ranging from weight loss and weight loss maintenance to weight gain and inability to lose weight.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/03/2024
Locations: University of Colorado, Denver, Denver, Colorado
Conditions: Weight Loss, Overweight, Obesity
Register for Updates