Advanced Cancer Clinical Trials

A listing of 49 Advanced Cancer clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

Home

All Conditions

Advanced Cancer

1 - 12 of 49

Show Filters

Match to Clinical Trials

Access to cutting-edge treatments

Latest clinical trials

Find trials in your area

Start Matching

Filter by Age

There are currently 49 active clinical trials seeking participants for Advanced Cancer research studies. The states with the highest number of trials for Advanced Cancer participants are Texas, California, Florida and New York.

Featured Trial

Paid Clinical Studies Nationwide

Recruiting

Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.

Conditions:

Healthy

Healthy Volunteer Study

Learn More

* Compensation for time may be available

Featured Offer

Lose Weight with GLP-1 Medications

Recruiting

Policy Lab has partnered with OnlineSemaglutide.org to offer trusted access to semaglutide and other GLP-1 medications, including generic alternatives to Ozempic® and Wegovy®.

GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.

As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.

Conditions:

Overweight

Overweight and Obesity

Obesity

Weight Loss

Morbid Obesity

Learn More

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

NCT05891171

Recruiting

The primary purpose of this study is to assess the safety and tolerability of AB598 in participants with advanced malignancies.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/30/2025

Locations: Mayo Clinic Arizona, Phoenix, Arizona +19 locations

Conditions: Advanced Cancer, Advanced Malignancies, Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer, Gastroesophageal-junction Cancer (GEJ), Head and Neck Squamous Cell Carcinoma (HNSCC), Non-Small Cell Lung Cancer (NSCLC), Ovarian Cancer, Renal Cell Carcinoma (RCC), Triple Negative Breast Cancer (TNBC)

Learn More ›

Phase 1b/2 Study of Combination 177Lu Girentuximab Plus Cabozantinib and Nivolumab in Treatment naïve Patients With Advanced Clear Cell RCC

NCT05663710

Recruiting

To learn if giving 177Lu girentuximab in combination with cabozantinib plus nivolumab can help to control advanced clear cell renal cell carcinoma (ccRCC).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/30/2025

Locations: MD Anderson Cancer Center, Houston, Texas

Conditions: Advanced Cancer, Clear Cell Renal Cell Carcinoma

Learn More ›

A Study of AB801 Monotherapy and Combination Therapy in Participants With Advanced Malignancies

NCT06120075

Recruiting

The primary purpose of this study is to assess the safety and tolerability of AB801 in participants with advanced malignancies, and to determine a recommended AB801 dose for expansion.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/30/2025

Locations: Sarah Cannon Research Institute, Denver, Colorado +9 locations

Conditions: Advanced Cancer

Learn More ›

Trial of Two Adagrasib Dosing Regimens in NSCLC With KRAS G12C Mutation (KRYSTAL 21)

NCT05853575

Recruiting

This study will evaluate the efficacy of two dosing regimens of adagrasib (600 mg BID versus 400 mg BID) in patients with NSCLC with KRAS G12C mutation.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/28/2025

Locations: Providence Medical Foundation - Research, Santa Rosa, California +114 locations

Providence Medical Foundation - Research, Santa Rosa, California

Local Institution - 104, Chicago, Illinois

Local Institution - 103, Minneapolis, Minnesota

Kansas City VA Hospital, Kansas City, Missouri

Veterans Affairs Medical Center (VAMC) - Durham - Oncology, Durham, North Carolina

VA North Texas Healthcare System/Dallas VA Medical Center, Dallas, Texas

Hospital Sao Lucas da PUCRS, Porto Alegre, Rio Grande Do Sul

Clinica de Neoplasias Litoral, Itajaí, Santa Catarina

Oncocentro Belo Horizonte, Belo Horizonte, São Paulo

AMO Assistencia Multidisciplinar em Oncologia, Salvador, Not set

A.C. Camargo Cancer Center, São Paulo, Not set

Klinički bolnički centar Sestre milosrdnice, Zagreb, Grad Zagreb

Local Institution - 525, Pula, Istarska Županija

Hopital Haut-Leveque - Maladies respiratoires, Pessac, Gironde

Institut de Cancerologie de I'Ouest - Service d'Oncologie Medicale - Service d'Oncologie Médicale, Saint-Herblain Cedex, Loire-Atlantique

Centre Hospitalier Universitaire D' Angers Hôpital Larrey - PNEUMOLOGIE, Angers, Maine-et-Loire

Centre Hospitalier Universitaire de Poitiers - Service d'oncologie Médicale Oncologie Medicale - Cancerolo, Poitiers, Poitou-Charentes

CHU de Grenoble, Grenoble, Rhône-Alpes

AP-HM Hopital Nord, Marseille, Rhône

Centre Hosptalier De Villefranche-Sur-Saone - Oncologie Medicale - Cancerolo, Villefranche Sur Saone, Rhône

Centre Hôspitalier de Bretagne Sud - Hôpital du Scorff, Lorient, Not set

CHU de Nantes - Hôpital Nord Laënnec (HGRL), Nantes cedex 1, Not set

Local Institution - 562, Paris, Not set

Centre Hospitalier de Cornouaille, Quimper, Not set

Hôpital Bégin - Service d'Oncologie, Saint-Mandé, Not set

University of Patras, Patra, Achaïa

General Hospital of Athens "Alexandra", Athens, Attiki

Local Institution - 582, Athens, Attiki

University General Hospital Attikon, Haidari - Athens, Attiki

St. Luke's Hospital S.A., Panorama, Not set

Theageneio Cancer Hospital, Thessaloniki, Not set

General Hospital Of Thessaloniki Papageorgiou, Thessaloniki, Not set

Local Institution - 600, Szolnok, Jász-Nagykun-Szolnok

Bnai Zion Medical Center Rheumatology Unit, Haifa, Tel-Aviv

Assuta Medical Center, Tel Aviv-Yafo, Tel-Aviv

Shaare Zedek Medical center, Jerusalem, Yerushalayim

Rambam Health Care Campus, Haifa, Not set

Tel Aviv Sourasky Medical Center - Oncology - Hematology/Oncology, Tel-Aviv, Not set

Azienda Sanitaria Territoriale Pesaro Urbino (AST PU), Pesaro, Pesaro E Urbino

Azienda Ospedaliero-Universitaria Maggiore Della Carita, Novara, Piemonte

Istituto di Candiolo, IRCCS, Candiolo, Torino

IEO - Istituto Europeo di Oncologia, IRCCS, Milano, Not set

Ospedale S.Maria della Misericordia, AO di Perugia, Università degli Studi di Perugia, Perugia, Not set

Istituto Nazionale Tumori Regina Elena - IRCCS - IFO, Roma, Not set

Local Institution - 401, Toon, Ehime

Local Institution - 403, Nishinomiya, Hyôgo [Hyogo]

Local Institution - 402, Kashiwa, Tiba [Chiba]

National Cancer Center, Goyang-Si, Gyeonggido [Kyonggi-do]

Samsung Medical Center, Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi]

Korea University Guro Hospital, Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi]

Gangnam Severance Hospital - Oncology, Seoul, Seoul Teugbyeolsi [Seoul-T'ukp

Local Institution - 128, Tuxtla Gutiérrez, Chiapas

Local Institution - 127, Col. Roma, Distrito Federal

Local Institution - 129, Nápoles, Mexico City

Local Institution - 125, Toluca, Not set

Local Institution - 802, Breda, Noord-Brabant

Anthoni van Leeuwenhoek Ziekenhuis, Nederlands Kanker Instit, Amsterdam, Noord-Holland

St. Antonius Hospital, Utrecht, Not set

Local Institution - 152, San Martin de Porres, Lima

Local Institution - 151, Surquillo, Lima

Pratia MCM Krakow, Krakow, Malopolskie

Szpitale Pomorskie Sp. z o.o. - Oddzial Onkologii i Radioterapii - Oddzial Onkologii Klinicznej, Gdynia, Pomorskie

MS Pneumed Janusz Milanowski, Katarzyna Szmygin-Milanowska Sp. Jawna, Lublin, Not set

Medisprof - Medical Oncology, Cluj-Napoca, Cluj

Ovidius Clinical Hospital, Ovidiu, Constanta

Local Institution - 727, Craiova, Dolj

Oncolab - Medical Oncology, Craiova, Dolj

Centrul de Oncologie Sf Nectarie - Medical Oncology, Craiova, Dolj

Oncocenter- Oncologie Clinica - Medical Oncology, Timisoara, Timis

Centrul de Oncologie Euroclinic, Iasi, Not set

Spitalul Clinic Judetean De Urgenta Sibiu, Sibiu, Not set

Sigmedical Services S.R.L., Suceava, Not set

University Clinical Center of Nis, Clinic for Pediatrics-Department for Pulmonology, Nis, Vojvodina

Local Institution - 750, Sremska Kamenica, Vojvodina

Local Institution - 753, Belgrade, Not set

Local Institution - 751, Belgrade, Not set

University Clinical Center of Kragujevac, Center for Internal Oncology, Kragujevac, Šumadijski Okrug

Complejo Hospitalario Universitario De Santiago - Oncología Médica, Santiago de Compostela, A Coruña

Hospital Regional Universitario De Málaga, Malaga, Andalucía

Hospital Universitario Central de Asturias, Oviedo, Asturias

Hospital Universitario Son Espases, Palma de Mallorca, Baleares

Local Institution - 686, Santander, Cantabria

Local Institution - 684, Valencia, Valenciana, Comunidad

Hospital de la Santa Creu i Sant Pau, Barcelona, Not set

Hospital Universitari Dexeus Grupo Quironsalud, Barcelona, Not set

Hospital Universitario Vall d'Hebron - Oncología Médica, Barcelona, Not set

Local Institution - 689, Barcelona, Not set

Hospital General Universitario Gregorio Marañón - Oncología Médica, Madrid, Not set

Hospital General Universitario Gregorio Marañón, Madrid, Not set

M.D. Anderson Center Madrid, Madrid, Not set

Hospital Clínico San Carlos, Madrid, Not set

Hospital Universitario Virgen de la Macarena - Oncología Médica, Sevilla, Not set

Hospital Clinico Universitario De Valencia - Oncologia Médica y Hematologia, Valencia, Not set

Local Institution - 351, Kaohsiung City, Kaohsiung

Chung Shan Medical University Hospital, Taichung City, Taichung

China Medical University Hospital - Internal Medicine, Taichung City, Taichung

Local Institution - 355, Taichung City, Taichung

Local Institution - 354, Taipei City, Taipei

Local Institution - 376, Muang, Chiang Mai

Siriraj Hospital - Medical Oncology, Bangkok, Krung Thep Maha Nakhon [Bangko

Srinagarind Hospital - ACADEMIC CLINICAL RESEARCH OFFICE, Khon Kaen, Not set

Holistic Center for Cancer Study and Care, Songkhla, Not set

Memorial Ankara Hastanesi, Ankara, Ankara/Cankaya

Istanbul Oncology Hospital - Medical Oncology, Istanbul, Samsun

Local Institution - 703, Istanbul, Samsun

Gulhane Training and Research Hospital - Medical Oncology, Ankara, Not set

Dr Abdurrahman Yurtaslan Training and Research Hospital - Medical Oncology, Ankara, Not set

Ankara Liv Hospital, Ankara, Not set

Ankara City Hospital - Medical Oncology, Ankara, Not set

Trakya Univ Hastanesi Ic Hastal, Edirne, Not set

Medipol Mega Universite Hastanesi Tibbi Onkoloji, Istanbul, Not set

Goztepe SuleymanYalcin Sehir Hast, Istanbul, Not set

Ege University Medical Faculty - Pulmonary, Izmir, Not set

Conditions: Advanced Cancer, Metastatic Cancer, Malignant Neoplasm of Lung

Learn More ›

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

NCT05735080

Recruiting

Incyclix Bio (Incyclix) is developing INX-315 as an oral, small molecule inhibitor of cyclin dependent kinase 2 (CDK2) for the treatment of human cancers. This first-in-human study is designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary antitumor activity of INX-315 in patients with recurrent advanced/metastatic cancer, including hormone receptor positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2-) breast cancer who progressed on a prior cyclin... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/22/2025

Locations: Florida Cancer Specialists, Lake Mary, Florida +15 locations

Conditions: Breast Cancer, Breast Cancer Metastatic, Hormone Receptor Positive Tumor, Human Epidermal Growth Factor 2 Negative Carcinoma of Breast, Ovarian Cancer, CCNE1 Amplification, Solid Tumor, Advanced Cancer, Metastatic Cancer

Learn More ›

Phase 1/2 Study of MRTX849 in Patients With Cancer Having a KRAS G12C Mutation KRYSTAL-1

NCT03785249

Recruiting

This study will evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with advanced solid tumors that have a KRAS G12C mutation.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/14/2025

Locations: ONeal Comprehensive Cancer Center at the University of Alabama at Birmingham, Birmingham, Alabama +227 locations

ONeal Comprehensive Cancer Center at the University of Alabama at Birmingham, Birmingham, Alabama

Alaska Oncology and Hematology, Anchorage, Alaska

Mayo Clinic Arizona - Phoenix Campus, Phoenix, Arizona

Local Institution - 001-807, Scottsdale, Arizona

Local Institution - 001-873-A, Tucson, Arizona

USOR - Arizona Oncology - Tucson - Rudasill, Tucson, Arizona

Local Institution - 001-840-B, Bellflower, California

Beverly Hills Cancer Center, Beverly Hills, California

City of Hope - Duarte (Main Campus), Duarte, California

Local Institution - 001-850-K, Dublin, California

Providence Medical Foundation - Virginia K. Crosson Cancer Center - Fullerton, Fullerton, California

Local Institution - 001-840-C, Harbor City, California

University of California San Diego Moores Cancer Center, La Jolla, California

TRIO - Cancer and Blood Specialty Clinic, Los Alamitos, California

Southern California Permanente Medical Group - Los Angeles Medical Center, Los Angeles, California

Valkyrie Clinical Trials, Los Angeles, California

Hoag Memorial Hospital Presbyterian - Newport Beach, Newport Beach, California

Local Institution - 001-850-B, Oakland, California

University of California Irvine Medical Center, Orange, California

Local Institution - 001-850-C, Roseville, California

Local Institution - 001-850-J, Sacramento, California

Local Institution - 001-850-D, Sacramento, California

California Cancer Associates for Research and Excellence (cCARE) - San Diego 4S Ranch, San Diego, California

Local Institution - 001-840-A, San Diego, California

Local Institution - 001-850-H, San Francisco, California

Local Institution - 001-850-E, San Francisco, California

Local Institution - 001-850-F, San Jose, California

Local Institution - 001-850-A, San Leandro, California

Ridley - Tree Cancer Center - Santa Barbara, Santa Barbara, California

Local Institution - 001-850-I, Santa Clara, California

Local Institution - 001-884-A, Solvang, California

Kaiser Permanente - Vallejo Medical Center, Vallejo, California

Local Institution - 001-850-G, Walnut Creek, California

USOR - Rocky Mountain Cancer Centers - Aurora, Aurora, Colorado

UCHealth Cancer Care - Anschutz Medical Campus - University of Colorado Cancer Center, Aurora, Colorado

Local Institution - 001-872-H, Boulder, Colorado

Local Institution - 001-872-E, Colorado Springs, Colorado

Local Institution - 001-872-L, Colorado Springs, Colorado

Local Institution - 001-872-B, Denver, Colorado

Local Institution - 001-951 - A, Denver, Colorado

Local Institution - 001-951 - B, Denver, Colorado

Cancer Centers of Colorado - St. Marys Regional Hospital, Grand Junction, Colorado

SCL Health - Saint Joseph Hospital Cancer Center, Lafayette, Colorado

Local Institution - 001-872-A, Lakewood, Colorado

Local Institution - 001-872-D, Littleton, Colorado

Local Institution - 001-872-K, Lone Tree, Colorado

Local Institution - 001-872-C, Longmont, Colorado

Local Institution - 001-872-J, Parker, Colorado

Local Institution - 001-872-F, Pueblo, Colorado

Local Institution - 001-872-G, Pueblo, Colorado

Local Institution - 001-872-I, Thornton, Colorado

Yale Cancer Center, New Haven, Connecticut

USOR - Medical Oncology Hematology Consultants, Newark, Delaware

Local Institution - 001-929i, Altamonte Springs, Florida

Boca Raton Clinical Research Associates, Inc., Boca Raton, Florida

Local Institution - 001-922A, Bonita Springs, Florida

Local Institution - 001-922D, Bradenton, Florida

Local Institution - 001-929c, Brandon, Florida

Local Institution - 001-922E, Cape Coral, Florida

Local Institution - 001-929g, Clearwater, Florida

Local Institution - 001-926b, Daytona Beach, Florida

SCRI - Florida Cancer Specialists - South Region Research Office, Fort Myers, Florida

Local Institution - 001-922B, Fort Myers, Florida

Local Institution - 001-922C, Fort Myers, Florida

Local Institution - 001-929b, Gainesville, Florida

Mayo Clinic - Jacksonville, Jacksonville, Florida

Local Institution - 001-929m, Lady Lake, Florida

Local Institution - 001-929e, Largo, Florida

Local Institution - 001-929n, Lecanto, Florida

Mount Sinai Comprehensive Cancer Center, Miami Beach, Florida

Miami Cancer Institute, Miami, Florida

Local Institution - 001-922F, Naples, Florida

Local Institution - 001-922G, Naples, Florida

Florida Cancer Affiliates - Ocala - Main, Ocala, Florida

Local Institution - 001-929p, Ocala, Florida

Local Institution - 001-929j, Orange City, Florida

Mid Florida Cancer Centers - Orange City, Orange City, Florida

Local Institution - 001-929l, Orlando, Florida

Woodlands Medical Specialists, Pensacola, Florida

Local Institution - 001-922H, Port Charlotte, Florida

Local Institution - 001-929a, Saint Petersburg, Florida

SCRI - Florida Cancer Specialists - North Region Research Office, Saint Petersburg, Florida

Local Institution - 001-922I, Sarasota, Florida

Local Institution - 001-922J, Sarasota, Florida

Local Institution - 001-929h, Spring Hill, Florida

Local Institution - 001-926d, Stuart, Florida

Local Institution - 001-929d, Tampa, Florida

Local Institution - 001-929k, Tavares, Florida

Local Institution - 001-929f, Trinity, Florida

Local Institution - 001-922K, Venice, Florida

Local Institution - 001-922L, Venice, Florida

Local Institution - 001-926c, Vero Beach, Florida

Local Institution - 001-926a, Wellington, Florida

SCRI - Florida Cancer Specialists - East Region Research Office, West Palm Beach, Florida

Local Institution - 001-929o, Winter Park, Florida

University Cancer & Blood Center (UCBC) - Athens, Athens, Georgia

Local Institution - 001-835-C, Austell, Georgia

Local Institution - 001-835-E, Austell, Georgia

Local Institution - 001-835-D, Carrollton, Georgia

Local Institution - 001-835-F, Carrollton, Georgia

Local Institution - 001-835-A, Cartersville, Georgia

Local Institution - 001-835-B, Douglasville, Georgia

Northwest Georgia Oncology Centers Wellstar - Marietta, Marietta, Georgia

Affiliated Oncologists, LLC, Chicago Ridge, Illinois

Local Institution - 001-828, Chicago, Illinois

USOR - Illinois Cancer Specialists - Niles, Niles, Illinois

Memorial Hospital, South Bend, Indiana

University of Iowa, Iowa City, Iowa

University of Kansas Medical Center, Westwood, Kansas

University of Kentucky, Lexington, Kentucky

SCRI - Hematology Oncology Clinic - Baton Rouge, Baton Rouge, Louisiana

MaineHealth Cancer Care - Biddeford, Biddeford, Maine

Local Institution - 001-881-B, Brandywine, Maryland

Maryland Oncology Hematology - Columbia, Columbia, Maryland

Local Institution - 001-881-A, Silver Spring, Maryland

Dana-Farber Cancer Institute, Boston, Massachusetts

Barbara Ann Karmanos Cancer Institute, Detroit, Michigan

Henry Ford Health System, Detroit, Michigan

Local Institution - 001-842-A, Farmington Hills, Michigan

Local Institution - 001-838-F, Coon Rapids, Minnesota

Local Institution - 001-838-E, Edina, Minnesota

Local Institution - 001-875 - D, Edina, Minnesota

Local Institution - 001-838-D, Maplewood, Minnesota

Local Institution - 001-875 - A, Maplewood, Minnesota

Local Institution - 001-838-C, Minneapolis, Minnesota

USOR - Minnesota Oncology - Minneapolis Clinic, Minneapolis, Minnesota

Local Institution - 001-838-G, Minneapolis, Minnesota

Local Institution - 001-822-A, Minneapolis, Minnesota

Masonic Cancer Center, Minneapolis, Minnesota

Mayo Clinic - Rochester, Rochester, Minnesota

Metro-Minnesota Community Oncology Research Consortium (MMCORC), Saint Louis Park, Minnesota

Local Institution - 001-838-B, Saint Louis Park, Minnesota

Local Institution - 001-838-A, Saint Paul, Minnesota

Local Institution - 001-875 - B, Saint Paul, Minnesota

Local Institution - 001-875 - C, Woodbury, Minnesota

Central Care Cancer Center - Bolivar, Bolivar, Missouri

Goldschmidt Cancer Center, Jefferson City, Missouri

Sisters of Charity of Leavenworth Health St. Marys, Billings, Montana

Local Institution - 001-544B, Omaha, Nebraska

Methodist Estabrook Cancer Center, Omaha, Nebraska

Local Institution - 001-544A, Omaha, Nebraska

University of Nebraska Medical Center, Omaha, Nebraska

Local Institution - 001-860A, Henderson, Nevada

Local Institution - 001-860C, Henderson, Nevada

Local Institution - 001-860B, Henderson, Nevada

USOR - Comprehensive Cancer Centers of Nevada - Southeast Henderson, Henderson, Nevada

Local Institution - 001-860E, Las Vegas, Nevada

Local Institution - 001-860D, Las Vegas, Nevada

Local Institution - 001-860F, Las Vegas, Nevada

New York Oncology Hematology - Albany Medical Center, Albany, New York

Roswell Park Comprehensive Cancer Center, Buffalo, New York

Local Institution - 001-832, Lake Success, New York

Perlmutter Cancer Center - 34th Street, New York, New York

Local Institution - 001-583, New York, New York

Memorial Sloan Kettering Cancer Center - New York, New York, New York

University of North Carolina Hospitals, Chapel Hill, North Carolina

FirstHealth Outpatient Cancer Center, Pinehurst, North Carolina

The Christ Hospital, Cincinnati, Ohio

University of Cincinnati Health Barrett Cancer Center, Cincinnati, Ohio

Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio

Local Institution - 001-833 - H, Columbus, Ohio

Local Institution - 001-833 - C, Columbus, Ohio

Local Institution - 001-833 - J, Columbus, Ohio

Local Institution - 001-833 - A, Columbus, Ohio

Local Institution - 001-833 - F, Columbus, Ohio

The Ohio State University College of Medicine, Columbus, Ohio

Local Institution - 001-833 - D, Columbus, Ohio

Local Institution - 001-833 - I, Columbus, Ohio

SCRI - Mark H. Zangmeister Cancer Center, Columbus, Ohio

Local Institution - 001-833 - B, Columbus, Ohio

Local Institution - 001-833 - G, Columbus, Ohio

Local Institution - 001-833 - E, Gahanna, Ohio

Kettering Health Cancer Center - Main Campus, Kettering, Ohio

Local Institution - 001-836-A, Kettering, Ohio

Cancer Centers of Southwest Oklahoma - Leah M. Fitch Cancer Center, Lawton, Oklahoma

Local Institution - 001-580, Oklahoma City, Oklahoma

Local Institution - 001-584, Tulsa, Oklahoma

Local Institution - 001-586-A, Bend, Oregon

St. Charles Health System, Bend, Oregon

Willamette Valley Cancer Institute and Research Center - Eugene, Eugene, Oregon

Lehigh Valley Physician Group Hematology Oncology, Allentown, Pennsylvania

Local Institution - 001-837-A, Bethlehem, Pennsylvania

Penn State Cancer Institute, Hershey, Pennsylvania

USOR - Alliance Cancer Specialists - Media (Cancer Center at Riddle Memorial Hospital), Media, Pennsylvania

USOR - Charleston Hematology Oncology Associates, Charleston, South Carolina

Medical University of South Carolina, Charleston, South Carolina

Local Institution - 001-801-G, Gallatin, Tennessee

Local Institution - 001-801-A, Hendersonville, Tennessee

Local Institution - 001-801-D, Hermitage, Tennessee

Local Institution - 001-801-F, Murfreesboro, Tennessee

Local Institution - 001-801-B, Nashville, Tennessee

Tennessee Oncology - Nashville - Centennial Clinic - Medical Oncology, Nashville, Tennessee

Local Institution - 001-801-E, Nashville, Tennessee

Local Institution - 001-801-C, Nashville, Tennessee

Local Institution - 001-888-B, Arlington, Texas

USOR - Texas Oncology Dallas Fort Worth West (DFWW) - Arlington South, Arlington, Texas

USOR - Texas Oncology - Austin Central, Austin, Texas

Local Institution - 001-848a, Conroe, Texas

Mary Crowley Cancer Research - Medical City Hospital, Dallas, Texas

USOR - Texas Oncology - Dallas Fort Worth (DFW) - Presbyterian Cancer Center Dallas, Dallas, Texas

USOR - Texas Oncology - Dallas Fort Worth (DFW) - Baylor Charles A. Sammons Cancer Center, Dallas, Texas

USOR - Texas Oncology Northeast Texas - Denison, Denison, Texas

Texas Oncology - Dallas Fort Worth (DFW) - Fort Worth, Fort Worth, Texas

Oncology Consultants - Texas Medical Center, Houston, Texas

University of Texas MD Anderson Cancer Center, Houston, Texas

Local Institution - 001-935A, Houston, Texas

Local Institution - 001-999, Irving, Texas

Local Institution - 001-935D, Kingwood, Texas

Lumi Research, Kingwood, Texas

USOR - Texas Oncology - Midland Allison Cancer Center, Midland, Texas

START Center for Cancer Care, San Antonio, Texas

Local Institution - 001-935B, Shenandoah, Texas

Local Institution - 001-935C, Spring, Texas

Texas Oncology - Sugar Land, Sugar Land, Texas

Local Institution - 001-935E, Tomball, Texas

Texas Oncology - Northeast Texas Cancer and Research Institute - Tyler, Tyler, Texas

Texas Oncology - Waco, Waco, Texas

Local Institution - 001-919, Fairfax, Virginia

NEXT Virginia, Fairfax, Virginia

Hematology Oncology Associates of Fredericksburg, Fredericksburg, Virginia

USOR - Virginia Oncology Associates - Newport News, Newport News, Virginia

Local Institution - 001-882-A, Norfolk, Virginia

Local Institution - 001-890-A, Norfolk, Virginia

Virginia Cancer Institute - West End, Richmond, Virginia

Fred Hutchinson Cancer Research Center, Seattle, Washington

USOR - Northwest Cancer Specialists, P.C. dba Compass Oncology - Vancouver Cancer Center, Vancouver, Washington

University Wisconsin Carbone Cancer Center, Madison, Wisconsin

PanOncology Trials - Rio Piedras Medical Center, San Juan, Not set

Conditions: Advanced Cancer, Metastatic Cancer, Malignant Neoplastic Disease

Learn More ›

Practical Geriatric Assessment (PGA) Implementation Strategies and Correlative Evaluations (PACE-70)

NCT06870617

Recruiting

The use of a geriatric assessment to inform oncologic care for older persons with cancer is an evidence-based practice that improves patient-clinician communication, reduces treatment-related toxicity, and is recommended by national guidelines. However, the implementation of a geriatric assessment can be time-consuming and burdensome, leading to suboptimal use in clinical practice. Developed and endorsed by the American Society for Clinical Oncology (ASCO), the Practical Geriatric Assessment (PG... Read More

Gender:

ALL

Ages:

70 years and above

Trial Updated:

07/10/2025

Locations: Penn Medicine Princeton Medical Center, Princeton, New Jersey +2 locations

Conditions: Geriatric Assessment, Advanced Cancer, Toxicity

Learn More ›

Psilocybin in Cancer Pain Study

NCT06001749

Recruiting

The overall objective of this study is to assess the feasibility, safety and preliminary efficacy of psilocybin-assisted therapy to alleviate opioid-refractory pain in patients with advanced-cancer. The name of the study intervention used in this research study is: Psilocybin (a tryptamine derivative)

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/09/2025

Locations: Dana-Farber Cancer Institute, Boston, Massachusetts

Conditions: Opioid-Related Disorders, Pain Management, Pain Management and Care, Advanced Cancer, Advanced Cancers

Learn More ›

Evaluation of RBS2418 in Subjects With Advanced, Metastatic Solid Tumors

NCT05270213

Recruiting

RBS2418 (investigational product) is a specific immune modulator, working through ectonucleotide pyrophosphatase/phosphodiesterase I (ENPP1), designed to lead to anti-tumor immunity by increasing endogenous 2'-3'-cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) and adenosine triphosphate (ATP levels) and reducing adenosine production in the tumors. RBS2418 has the potential to be an important therapeutic option for subjects both as monotherapy and in combination with other cancer t... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/09/2025

Locations: Honor Health Research Institute, Scottsdale, Arizona +13 locations

Conditions: Advanced Cancer

Learn More ›

First-in-Human Study of OKI-219 in Advanced Solid Tumors and Advanced Breast Cancer

NCT06239467

Recruiting

OKI-219-101 is a Phase 1a/1b, open-label, multicenter, dose-escalation study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PDx), and efficacy of OKI-219 as monotherapy and in combination with fulvestrant or trastuzumab. Phase 1a (Part A) will investigate escalating doses of OKI-219 monotherapy, and Phase 1b will investigate OKI-219 (at a tolerated dose determined in Part A) in combination with standard dose fulvestrant (Part B) or standard dose trastuzum... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/26/2025

Locations: California Cancer Associates for Research and Excellence, Encinitas, California +33 locations

California Cancer Associates for Research and Excellence, Encinitas, California

University of California San Diego UCSD, La Jolla, California

UCLA Jonsson Comprehensive Cancer Center, Los Angeles, California

Hoag - Huntington Beach, Newport Beach, California

Regents of the University of Colorado, Aurora, Colorado

Sarah Cannon Research Institute at HealthONE, Denver, Colorado

Massachusetts General Hospital, Boston, Massachusetts

Karmanos Cancer Insitute, Detroit, Michigan

Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada

Stony Brook University, Stony Brook, New York

SCRI Oncology Partners - Nashville, Nashville, Tennessee

NEXT Oncology Virginia, Fairfax, Virginia

Fred Hutchinson Cancer Center, Seattle, Washington

Institut Jules Bordet, Anderlecht, Not set

UZ Leuven - Campus Gasthuisberg, Leuven, Not set

GZA Hopsitals Campus Sint-Augustinus, Wilrijk, Not set

Centre de Lutte Contre le Cancer CLCC - Centre Georges Francois Leclerc (CGFL), Dijon, Not set

Centre Oscar Lambret, Lille, Not set

Centre Leon Berard, Lyon, Not set

Centre Antoine Lacassagne, Nice, Not set

Hopital Lyon Sud, Pierre Benite, Not set

Institut Gustave Roussy, Villejuif, Not set

Ospedale San Raffaele, Milano, Not set

Ospedale San Gerardo-ASST Monza, Monza, Not set

Istituto Clinico Humanitas, Rozzano, Not set

Gachon University Gil Medical Center, Incheon, Not set

Seoul National University Hospital, Seoul, Not set

Severance Hospital, Seoul, Not set

Asan Medical Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

NEXT Oncology Phase I Unit / IOB- Hospital Quironsalud Barcelona, Barcelona, Not set

Hospital Beata Maria Ana, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

START - Madrid, Madrid, Not set

Conditions: Advanced Cancer, Breast Cancer

Learn More ›

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

NCT03175224

Recruiting

To assess: * efficacy of APL-101 as monotherapy for the treatment of NSCLC harboring MET Exon 14 skipping mutations, NSCLC harboring MET amplification, solid tumors harboring MET amplification, solid tumors harboring MET fusion, primary CNS tumors harboring MET alterations, solid tumors harboring wild-type MET with overexpression of HGF and MET * efficacy of APL-101 as an add-on therapy to EGFR inhibitor for the treatment of NSCLC harboring EGFR activating mutations and developed acquired resis... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/24/2025

Locations: Cedars-Sinai Medical Center - Samuel Oschin Comprehensive Cancer Institute, Los Angeles, California +34 locations

Cedars-Sinai Medical Center - Samuel Oschin Comprehensive Cancer Institute, Los Angeles, California

Moffitt, Tampa, Florida

Dana Farber Cancer Institute, Boston, Massachusetts

University of North Carolina, Chapel Hill, North Carolina

Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania

University of Wisconsin, Madison, Wisconsin

St Vincents Hospital Melbourne, Melbourne, Not set

Cross Cancer Institute, Edmonton, Not set

McGill University Health Center - Research Institute, Montréal, Not set

Princess Margaret Hospital, Toronto, Not set

Cancer Care Manitoba, Winnipeg, Not set

CHRU de Brest - Hôpital Morvan, Brest, Not set

Centre Leon Berard, Lyon, Not set

Centre d'Essais Precoces en Cancerologie de Marseille, Marseille, Not set

Hopital Bichat - Claude Bernard - AP-HP, Paris, Not set

Gustave Roussy, Villejuif, Not set

Orszagos Koranyi Pulmonologiai Intezet, Budapest, Not set

Komarom-Esztergom Varmegyei Szent Borbala Korhaz, Tatabanya, Not set

IRCCS Azienda Ospedaliero-Universitaria di Bologna - Policlinico di Sant'Orsola, Bologna, Not set

Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Meldola, Not set

Istituto Europeo di Oncologia, Milano, Not set

IRCCS Ospedale San Raffaele, Milan, Not set

Istituto Oncologico Veneto-I.R.C.C.S. - Ospedale Busonera, Padova, Not set

Private Medical Institution Euromedservice, Saint Petersburg, Not set

National Cancer Centre Singapore, Singapore, Not set

Hospital Germans Trias i Pujol, Badalona, Not set

Hospital Clinic Barcelona, Barcelona, Not set

Hospital del Mar, Barcelona, Not set

Institut Catala d'Oncologia - L'Hospitalet, Barcelona, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Instituto Valenciano de Oncologia, Valencia, Not set

National Taiwan University Hospital, Taipei City, Not set

University College London Hospital, London, Not set

The Christie NHS Foundation Trust, Manchester, Not set

Royal Marsden Hospital - Surrey, Surrey Quays, Not set

Conditions: Advanced Cancer, Renal Cancer, Gastric Cancer, Gastroesophageal Junction Adenocarcinoma, NSCLC, Lung Cancer, Brain Tumor, Glioblastoma Multiforme, Solid Tumors, EGFR Gene Mutation, MET Amplification, HGF, Thyroid Cancer, Pancreatic Cancer, Colon Cancer, MET Alteration, MET Fusion, Exon 14 Skipping

Learn More ›

A Study of MGC026 in Participants With Advanced Solid Tumors

NCT06242470

Recruiting

The study is designed to understand the safety, tolerability, pharmacokinetics, immunogenicity, and preliminary antitumor activity of MGC026 in participants with relapsed or refractory, unresectable, locally advanced or metastatic solid tumors The study has a dose escalation portion and a cohort expansion portion of the study. Participants will receive MGC026 by intravenous (IV) infusion. The dose of MGC026 will be assigned at the time of enrollment. Participants may receive up to 35 treatments... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/23/2025

Locations: The Angeles Clinic and Research Institute, Los Angeles, California +10 locations

Conditions: Advanced Solid Tumor, Advanced Cancer, Metastatic Cancer, Squamous Cell Carcinoma of Head and Neck, Non Small Cell Lung Cancer, Small-cell Lung Cancer, Bladder Cancer, Sarcoma, Endometrial Cancer, Melanoma, Castration Resistant Prostatic Cancer, Cervical Cancer, Colorectal Cancer, Gastric Cancer, Gastro-esophageal Cancer, Pancreas Cancer, Clear Cell Renal Cell Carcinoma, Hepatocellular Carcinoma, Platinum-resistant Ovarian Cancer, Breast Cancer, Ovarian Cancer, Esophageal Squamous Cell Cancer (SCC)

Learn More ›

1 - 12 of 49