There are currently 32 active clinical trials seeking participants for Anesthesia research studies. The states with the highest number of trials for Anesthesia participants are California, Texas, Ontario and Quebec.
Impact of Atelectasis on RVEDP Following Orthotropic Heart Transplantation
NCT06140810
Recruiting
Following orthoptopic heart transplantation (OHT), children undergo surveillance cardiac catheterizations to assess for signs of rejection including muscle biopsy as well as pressure measurements to guide post transplant treatment regiments. These procedures are done under general anesthesia which promotes lung tissue collapse (atelectasis). What is not known is the effect of atelectasis on intracardiac pressures which are a critical area of monitoring post-transplant patients for rejection.
Gender:
All
Ages:
All
Trial Updated:
12/20/2023
Locations: Texas Childrens Hospital, Houston, Texas
Conditions: Heart Transplant Failure, Anesthesia
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Investigation of Pupillometry as Guide for Extubation Readiness in Anesthetized Children
NCT04947397
Recruiting
Investigation of pupillometry as guide for extubation readiness in anesthetized children.
Gender:
All
Ages:
Between 2 years and 10 years
Trial Updated:
12/19/2023
Locations: UCSF Benioff Children's Hospital Oakland, Oakland, California
Conditions: Anesthesia, Laryngospasm on Emergence
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Comparison of Intubation Conditions During Rapid Sequence Induction Obtained With Modified Time Principal Induction With a Standard Intubation Dose of Rocuronium Versus Succinylcholine
NCT06029049
Recruiting
The purpose of this study is to assess and compare conditions for tracheal intubation obtained with modified time principal induction with 0.6 mg/kg rocuronium and 1 mg/kg succinylcholine. Specifically, the investigators will be evaluating ease of laryngoscopy, vocal cord view, vocal cord opening, and movement of limbs and coughing during tracheal intubation in order to assess intubation conditions, to compare efficiency and success rate of tracheal intubation between two induction agents and to... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Anesthesia
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Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial
NCT05991453
Recruiting
The investigators will conduct a 12,500-patient randomized multi-center trial to determine (i) which general anesthesia technique yields superior patient recovery experiences in any of three surgical categories ((a) major inpatient surgery, (b) minor inpatient surgery, (c) outpatient surgery) and (ii) whether TIVA confers no more than a small (0.2 %) increased risk of intraoperative awareness than INVA in patients undergoing both outpatient and inpatient surgeries
Gender:
All
Ages:
18 years and above
Trial Updated:
11/22/2023
Locations: Yale School of Medicine, New Haven, Connecticut +5 locations
Conditions: Surgery-Complications, Anesthesia Complication, Anesthesia Awareness, Anesthesia, Surgery, Quality of Life, Pain, Postoperative, Anesthesia Morbidity, Depression, Sleep Disorders, Circadian Rhythm
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The Pediatric Anesthesia Quality Improvement Project
NCT00674388
Recruiting
The Study is designed to collect information about adverse events that occur in children undergoing anesthesia in participating hospitals. Demographic information will be collected on all anesthetics. An analysis of each adverse event will be performed and entered into the database. From this information we will devise strategies to prevent these adverse events.
Gender:
All
Ages:
21 years and below
Trial Updated:
11/20/2023
Locations: Phoenix Children's Hospital, Phoenix, Arizona +36 locations
Conditions: Surgery, Anesthesia, Children
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Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients
NCT03431064
Recruiting
In this research study we want to learn more about using non-invasive tools as a way to predict whether or not a child under general anesthesia will require and respond to fluid administration. It is important for an anesthesiologist to know if a child would respond to fluid administration so that they can provide the optimal intervention for low blood pressure and avoid unnecessary treatment.
Gender:
All
Ages:
17 years and below
Trial Updated:
11/08/2023
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Anesthesia, Intravenous Fluid, Blood Pressure
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Individual Cerebral Hemodynamic Oxygenation Relationships
NCT04435834
Recruiting
This is a randomized controlled trial in patients who require clinical anesthesia. The main purpose of this study is to understand whether there are differences in the cerebral blood flow, and oxygen metabolism affected by two types of anesthesia: propofol or sevoflurane. Subjects who require clinical anesthesia for a clinical MRI and for whom the use of propofol and sevoflurane are in clinical equipoise will be offered to have the anesthesia they will receive during their MRI randomized. All el... Read More
Gender:
All
Ages:
1 year and below
Trial Updated:
10/30/2023
Locations: Children's Hospital Los Angeles, Los Angeles, California
Conditions: Anesthesia, Anesthesia; Reaction
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Characterization of the Pudendal Nerve With Transvaginal Ultrasonography
NCT06021782
Recruiting
This is a feasibility study characterizing the ability of transvaginal ultrasonography to identify the pudendal nerve. Today, the pudendal nerve block is typically accomplished through blind landmark techniques, thus limiting its success. To date, there has never been an attempt to determine if the visualization of the pudendal nerve would be possible using transvaginal ultrasound with existing technology; nor to perform this procedure transvaginally with the assistance of ultrasound.
Gender:
Female
Ages:
18 years and above
Trial Updated:
08/26/2023
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Anesthesia
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Opioid-Free Anesthetic for Tonsillectomy
NCT04528173
Recruiting
Prospective randomized controlled trial to determine if opioid-free anesthetic for tonsillectomy is non-inferior to standard opioid-containing anesthetic
Gender:
All
Ages:
Between 2 years and 18 years
Trial Updated:
08/01/2023
Locations: The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania +1 locations
Conditions: Anesthesia, Opioid Use, Tonsillitis, Sleep Disorder, Surgery
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Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)
NCT05358535
Recruiting
The purpose of this study is to evaluate the hemodynamics and adverse event profile in comparison between two treatment arms, one using an admixture of propofol and etomidate at a ratio by volume of 25%/75% (P2E7), and one using an admixture of propofol and etomidate at a ratio by volume of 75%/25% (P7E2), for anesthesia during endoscopic procedures at the Clements University Hospital (CUH) endoscopy lab (Endo).
Gender:
All
Ages:
18 years and above
Trial Updated:
07/27/2023
Locations: Clements University Hospital, Dallas, Texas
Conditions: Anesthesia, Propofol Adverse Reaction, Etomidate Adverse Reaction, Anesthesia Complication, Anesthesia; Adverse Effect, Anesthesia; Reaction
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Memory & Conditioning Under Anesthesia
NCT04062123
Recruiting
The purpose of this study is to determine the effects of pain on long-term memory and conditioned physiologic responses in the presence and absence of distinct intravenous anesthetics. Functional magnetic resonance imaging will be used to identify the neural correlates of these phenomena The study will occur over 5 visits and involves no long-term follow up.
Gender:
All
Ages:
Between 18 years and 39 years
Trial Updated:
07/03/2023
Locations: University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
Conditions: Anesthesia, Pain
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Comparative Analysis of Spinal Anesthesia Versus General Anesthesia for vNOTES
NCT05688943
Recruiting
This study compares general anesthesia and spinal anesthesia for vNOTE tubal sterilization. A direct comparison of these methods has not been done before for this surgical approach. Investigators will aim to compare the two methods to determine the differences in perioperative complications, postoperative pain, postoperative nausea and vomiting, and the time to get the patient ready for discharge from the recovery room.
Gender:
Female
Ages:
21 years and above
Trial Updated:
05/20/2023
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Anesthesia, Tubal Ligation
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