There are currently 8 active clinical trials seeking participants for Bacterial Infections research studies. The states with the highest number of trials for Bacterial Infections participants are California, Florida, New York and Ohio.
Dose-finding, Pharmacokinetics, and Safety of VABOMERE in Pediatric Subjects With Bacterial Infections
NCT02687906
Recruiting
A single dose infusion of Vabomere (meropenem-vaborbactam) is being tested for dose-finding, pharmacokinetics, safety, and tolerability in pediatric subjects from birth to less than 18 years of age with serious bacterial infections
Gender:
ALL
Ages:
17 years and below
Trial Updated:
02/27/2025
Locations: Arkansas Children's Hospital, Little Rock, Arkansas +9 locations
Conditions: Bacterial Infections
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PK & Safety Study of Xeruborbactam Oral Prodrug Combined With Ceftibuten in Participants With Renal Impairment
NCT06157242
Recruiting
A Phase 1, open-label, single-dose study to determine the safety and pharmacokinetics of ORAvance (ceftibuten/xeruborbactam oral prodrug \[QPX7831\]) in participants with renal impairment
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/24/2025
Locations: University of Miami Clinical Pharmacology, Miami, Florida +1 locations
Conditions: Bacterial Infections
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A DDI Study to Investigate PK and Safety of Cefiderocol in Combination With Xeruborbactam in Healthy Adult Participants
NCT06547554
Recruiting
A phase 1, randomized, double blind, placebo controlled drug-drug interaction, pharmacokinetics and safety study of cefiderocol in combination with xeruborbactam in healthy adult participants
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
02/23/2025
Locations: Minneapolis Clinic, Minneapolis, Minnesota
Conditions: Bacterial Infections
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[18F]Fluoropropyl-Trimethoprim ([18F]F-TMP) PET/CT Imaging to Evaluate Biodistribution and Kinetics in Human Subjects
NCT04263792
Recruiting
The purpose of this study is to study a radioactive tracer, a type of imaging drug that is injected into the body to see how it is taken up in sites of active infection using an imaging procedure called Positron Emission Tomography/Computed Tomography (PET/CT).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/20/2025
Locations: University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Bacterial Infections
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A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants with HGG and Recurrent or Severe Infections Associated with B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin Lymphoma
NCT05645107
Recruiting
The primary purpose of the study is to evaluate whether biweekly administered XEMBIFY® plus Standard Medical Treatment (SMT) over a one-year period will reduce the rate of major bacterial infections per participant per year in B-cell CLL, MM, and NHL participants with hypogammaglobulinemia (HGG) in comparison to the Placebo plus SMT group.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/24/2024
Locations: GC2202 Study Site 103, Saint Petersburg, Florida +38 locations
Conditions: Hypogammaglobulinemia, Bacterial Infections, B-cell Chronic Lymphocytic Leukemia, Multiple Myleoma, Non-Hodgkin Lymphoma
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Study to Evaluate the PK of IV and PO Omadacycline in Children and Adolescents With Suspected or Confirmed Bacterial Infections
NCT05217537
Recruiting
The purpose of this study is to evaluate the pharmacokinetics of a single dose of intravenous or oral omadacycline in children and adolescents with suspected or confirmed bacterial infections.
Gender:
ALL
Ages:
Between 8 years and 17 years
Trial Updated:
08/21/2024
Locations: Site 109, Little Rock, Arkansas +8 locations
Conditions: Bacterial Infections
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Biodistribution and Pathophysiology Study of 11C-para-aminobenzoic Acid
NCT05611905
Recruiting
The investigators will perform radionuclide PET scans in subjects with infectious diseases to assess whether radio-labeled PABA (11C-PABA) is effective for infection imaging. Tomographic imaging can be used to evaluate disease processes deep within the body, noninvasively and relatively rapidly. The goal is to see if this imaging technique can help differentiate infections from non-infectious processes and also provide information on the causative bacterial class.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: Johns Hopkins Medical Institutions, Baltimore, Maryland
Conditions: Renal Excretion, Bacterial Infections, Inflammatory Disease, Oncologic Disease
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Effects of MRSA Bactericidal Gel To Promote Healing and Eliminate MRSA in cSSTI Vancogel(TM)
NCT00945152
Recruiting
Based on personal experience and the literature it is reasonable expectation that Vancomycin is a viable treatment in a direct contact form to eliminate MRSA from open wounds in order to heal the wounds by conventional means. The key question in my research has been to measure the effectiveness of my Vancomycin Gel by culturing the wound, applying the Gel in a controlled manner and then culturing the wound after one week. The end point to achieve in the process, is a clinical response of acceler... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/19/2022
Locations: Robert S Berman MD /661 Maplewood Drive #21, Jupiter, Florida
Conditions: Bacterial Infections, Wounds
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