There are currently 25 active clinical trials seeking participants for Breast Neoplasms research studies. The states with the highest number of trials for Breast Neoplasms participants are California, Texas, Florida and New York.
Focused Ultrasound and Gemcitabine in Breast Cancer
NCT04796220
Recruiting
This study will test the use of focused ultrasound ablation, low-dose gemcitabine (a chemotherapy) and the combination of focused ultrasound ablation plus low-dose gemcitabine in patients with early-stage breast cancers. We will be testing the effects of each of these regimens on cells in the immune system. We hypothesize that the combination of focused ultrasound ablation and gemcitabine will decrease myeloid-derived suppressor cells and will increase T cell activity. We also hypothesize that f... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/17/2024
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Breast Cancer, Breast Neoplasms
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A Study of Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer
NCT04975308
Recruiting
The main purpose of this study is to measure how well imlunestrant works compared to standard hormone therapy, and how well imlunestrant with abemaciclib work compared to imlunestrant in participants with breast cancer that is estrogen receptor positive (ER+) and human epidermal receptor 2 negative (HER2-). Participants must have breast cancer that is advanced or has spread to another part of the body. Study participation could last up to 5 years.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/17/2024
Locations: Ironwood Cancer & Research Centers, Chandler, Arizona +235 locations
Conditions: Breast Neoplasms, Neoplasm Metastasis
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Registry for Intra-Operative Radiotherapy During Breast Conserving Surgery in Patients With Early Stage Breast Cancer
NCT04603209
Recruiting
This is a prospective, registry study that will enroll all women with early stage breast cancer who will be treated with intraoperative radiotherapy (IORT) during breast-conserving surgery. The purpose of this study is to further validate the long-term effectiveness and safety of this treatment method. We aim to assess short and long-term patient outcomes associated with IORT, including perioperative complications, local and distance disease recurrences, as well as disease-free survival and over... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/15/2024
Locations: John Wayne Cancer Institute, Providence Saint John's Health Center, Santa Monica, California
Conditions: Early-stage Breast Cancer, Breast Carcinoma in Situ, Breast Neoplasms
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Effect of Neoadjuvant or Adjuvant Systemic Therapy on Breast Cancers, Bone Marrow Cancer Cells, and Circulating Cancer Cells
NCT00353483
Recruiting
The main purpose of this study is to compare genetic markers present on tumor cells before and after chemotherapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/15/2024
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Breast Neoplasms
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The Intestinal Microbiome in Triple Negative Breast Cancer Treated With Immunotherapy
NCT06318507
Recruiting
This study will determine how the intestinal microbiome differs between patients with obesity and early triple-negative breast cancer who achieve a pathologic complete response from preoperative anti-PD-1 immunotherapy (pembrolizumab) versus patients who do not.
Gender:
Female
Ages:
18 years and above
Trial Updated:
03/15/2024
Locations: Pennington Biomedical Research Center, Baton Rouge, Louisiana
Conditions: Breast Neoplasms
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A Culturally Sensitive Social Support Intervention
NCT02946697
Recruiting
This study is a randomized controlled trial (RCT) to assess the impact of a culturally based social support program (i.e. Joy Luck Academy, JLA) among Chinese American breast cancer survivors.
Gender:
Female
Ages:
18 years and above
Trial Updated:
02/20/2024
Locations: Herald Cancer Association, Los Angeles, California
Conditions: Breast Cancer, Breast Neoplasms
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Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score
NCT02476786
Recruiting
Multiple neoadjuvant endocrine trials demonstrate that women with good prognosis tumors can be identified. These trials have also demonstrated that there are not adverse effects on overall outcome if women are treated with neoadjuvant endocrine therapy for several months prior to definitive treatment. A new standard of care needs to be defined for elderly women with good prognosis estrogen receptor (ER)+ tumors, since these women may benefit from endocrine therapy alone to treat their cancer wit... Read More
Gender:
Female
Ages:
70 years and above
Trial Updated:
12/15/2023
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Breast Cancer, Cancer of Breast, Breast Neoplasms, Cancer of the Breast
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Biennial CEM in Women With a Personal History of Breast Cancer
NCT06105749
Recruiting
This is a prospective clinical trial that will examine if biennial contrast-enhanced mammography added to annual 3D mammography (tomosynthesis) substantially improves breast cancer detection with minimal increase in false-positives, in women with a personal history of breast cancer.
Gender:
Female
Ages:
Between 30 years and 79 years
Trial Updated:
10/23/2023
Locations: UPMC Magee-Womens Imaging - Bethel Park, Bethel Park, Pennsylvania +4 locations
Conditions: Breast Cancer, Breast Neoplasms, Breast Cancer Female, Neoplasms
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Breast Cancer Survivor Educational Intervention
NCT05700396
Recruiting
The goal of this study is to test a 6-week virtual education program among Black breast cancer survivors. The virtual program includes sessions on physical activity, goal setting, nutrition, sleep, stress, and social connections.
Gender:
Female
Ages:
22 years and above
Trial Updated:
09/22/2023
Locations: Massachusetts General Hospital Cancer Center, Boston, Massachusetts
Conditions: Breast Cancer, Breast Neoplasms, Breast Carcinoma, Breast Cancer Female
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Early Detection of Breast Cancer
NCT06043661
Recruiting
The TriNetra™ Breast test is intended for use as a breast cancer screening test that evaluates Circulating Tumor Cells (CTCs) associated with breast cancer. The TriNetra™Breast test should be a useful breast cancer screening option for asymptomatic women 40 years of age and older. This pivotal study is designed to provide evidence of test performance and to demonstrate its safety in the intended use population in the USA.
Gender:
Female
Ages:
40 years and above
Trial Updated:
09/18/2023
Locations: Rogel Cancer Center, Ann Arbor, Michigan
Conditions: Breast Neoplasms
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Delayed Sentinel Lymph Node Biopsy in Ductal Cancer in Situ
NCT04722692
Recruiting
The trial aims to investigate the use of superparamagnetic iron oxide (SPIO) nanoparticles as a tracer for delayed sentinel lymph node dissection (d-SLND) in patients where upfront axillary surgery (SLND) is oncologically deemed unnecessary and should be avoided. This includes but is not limited to patients with a preoperative diagnosis of ductal cancer in situ of the breast (DCIS), an unclear BIRADS 4-5 planned for diagnostic excision or women planned for risk reducing mastectomy. SPIO is injec... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
08/02/2023
Locations: Baylor College Of Medicine, Houston, Texas +8 locations
Conditions: DCIS, Breast Cancer, Breast Neoplasms, Sentinel Lymph Node
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Pharmacodynamic Biomarkers of Standard Anti-microtubule Drugs as Assessed by Early Tumor Biopsy
NCT03393741
Recruiting
Eligible subjects will be assigned to study treatment arms by their treating oncologist, rather than by the study. The drug, dose, and schedule of administration will be determined by the treating physician per NCCN guidelines for standard of care chemotherapy regimens for recurrent or metastatic breast cancer. Study treatment arms include: Taxane (nab-paclitaxel or paclitaxel), Eribulin, Vinorelbine, Ixabepilone, or the control arm (non-microtubule targeted chemotherapies such as doxorubicin, c... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/11/2023
Locations: University of Wisconsin Carbone Cancer Center, Madison, Wisconsin
Conditions: Breast Cancer, Breast Neoplasms
Register for Updates