There are currently 15 active clinical trials seeking participants for Burns research studies. The states with the highest number of trials for Autism participants are Texas, California, North Carolina and Florida.
Assessment of Safety and Effectiveness of NovoSorb® BTM in Severe Burns
Recruiting
This is a multi-center, pivotal study to assess the safety and effectiveness of a new method of treating severe burns using NovoSorb® Biodegradable Temporizing Matrix (BTM).
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
03/15/2024
Locations: Valleywise Health, Phoenix, Arizona +31 locations
Conditions: Burns
Coupling Negative Pressure Wound Therapy With Instillation
Recruiting
The objective of this study is to compare standard negative pressure wound therapy with negative pressure wound therapy coupled with instillation for optimal skin graft take. Either the V.A.C ULTA NPWT or V.A.C. VeraFlo Therapy systems with normal saline will be applied intra-operatively to split-thickness skin grafts of upper and lower extremity wounds and kept in place for a duration of four days. Following completion of four days, the skin graft with be assessed for percentage of take/adheren... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
03/11/2024
Locations: Loma Linda University, Loma Linda, California
Conditions: Wound, Ulcer, Burns
Burn Pivotal Study
Recruiting
The purpose of this study is to validate the algorithm for burn healing assessment by the Spectral MD DeepView device which would provide burn healing potential assessment.
Gender:
All
Ages:
All
Trial Updated:
03/04/2024
Locations: Valleywise Health, Phoenix, Arizona +3 locations
Conditions: Burns, Wound Heal, Wounds and Injuries
Impact of a Telerehabilitation Program With Technology Enhancement on Post-burn Recovery
Recruiting
The purpose of this study is to examine the effect of participating in a tele-rehabilitation program after a burn.
Gender:
All
Ages:
Between 18 years and 79 years
Trial Updated:
02/19/2024
Locations: University of Texas Medical Branch, Galveston, Texas
Conditions: Burns
Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns
Recruiting
To compare MW-III to Silvadene® Cream 1% (Silver Sulfadiazine) with respect to "time to healing" (≥95% re-epithelialization) of a partial thickness target thermal burn.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/06/2024
Locations: Valleywise Health Medical Center, Phoenix, Arizona +4 locations
Conditions: Burns
Safety of Extracellular Vesicles for Burn Wounds
Recruiting
Treatment of patients with deep second degree burns of the skin with extracellular vesicles (EV) isolated from bone marrow derived mesenchymal stem cells.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/18/2023
Locations: Ryder Trauma Center, Miami, Florida +1 locations
Conditions: Burns
DeepView Snapshot Handheld (DV-H) Comparison Study
Recruiting
his study is being done to collect pictures of burns using an investigational device called the Spectral MD Deep View Snapshot Handheld (DV-H), similar to a camera. The data collected will be used to assess the performance of the DV-H device, and to determine the device's ability to differentiate healing versus non-healing burn tissue. This device, if approved, is expected to give caregivers a better understanding of what parts of burn wounds will likely not heal on their own and as a tool used... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
11/07/2023
Locations: LSU Health New Orleans University Medical Center New Orleans, New Orleans, Louisiana
Conditions: Burns
Understanding the Burn Wound Microbiome: Comparing Traditional Wound Cultures to Next Generation Sequencing Technology
Recruiting
The purpose of this investigation is to better understand the wound microbiome in burn wounds and the role it plays in outcomes and complications related to treatment.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
10/30/2023
Locations: University of Texas Medical Branch, Galveston, Texas
Conditions: Microbial Colonization, Burns
Vitamin D Deficiency in Adults Following a Major Burn Injury
Recruiting
This is a single site double blind randomized controlled trial of replacing Vitamin D for Vitamin D-deficient burn patients at a current recommended dose (400 IU daily) versus a higher dose (4000 IU daily). Capsules will be made in a compounding pharmacy and will look identical. Randomized controlled trial. People who meet the selection criteria will be randomized to either low or high dosage of Vitamin D. Treatment arm is high dose Vitamin D (4000 IU), and control is low dose Vitamin D (400 IU... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/09/2023
Locations: Parkland Health and Hospital Systems, Dallas, Texas
Conditions: Vitamin D Deficiency, Burns
Plasma Resuscitation Without Lung Injury
Recruiting
The treatment of patients with major burns requires resuscitation with massive amounts of fluid, typically a type of salt water that is given by vein. This frequently results in injury to vital organs, especially the lungs and kidneys, and even in death. In this study, the investigators propose to use plasma, a specially prepared blood product made from the liquid part of blood, that has undergone special treatment to reduce the risk of disease transmission. The aims include 1) reduce the amount... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
09/06/2023
Locations: University of Alabama at Birmingham Burn Center, Birmingham, Alabama +6 locations
Conditions: Burns
Randomized Trial of Fresh Frozen Plasma Versus Albumin in Acute Burn Resuscitation
Recruiting
The investigators propose a prospective randomized trial to study fresh frozen plasma (FFP) versus albumin to determine the optimal colloid in burn resuscitations. This work addresses both FY20 focus areas, prolonged field care (PFC) and en route care, along with mitigating secondary effects of acute intervention, such as prevention of over resuscitation. Future military conflicts anticipate more extensive burn and blast injuries, and delayed evacuation. Therefore, the direct comparison of collo... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
04/13/2023
Locations: University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado
Conditions: Burns
Randomized Control Trial of CO2 Laser to Treat Hypertrophic Burn Scar
Recruiting
Laser treatment of hypertrophic burn scars has become increasingly popular for improving scarring in burn survivors. Despite its common use, there a gap in knowledge regrading randomized control trials that demonstrate whether the laser is beneficial. Such a trial is important because if it shows the laser does work, it would provide the evidence to make such treatments more accessible to all patients. Furthermore, there is no knowledge whether the burn injury used to remove tissue is beneficia... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/28/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Burns, Hypertrophic Scar