There are currently 143 active clinical trials seeking participants for Cardiovascular Diseases research studies. The states with the highest number of trials for Cardiovascular Diseases participants are California, Florida, Texas and New York.
A Pragmatic Trial of Chronic Disease Approaches to Ameliorate Tobacco Related Cardiovascular Disease Health Disparities
NCT05671380
Recruiting
This project will evaluate a proactive outreach intervention for tobacco cessation among primary care BIPOC populations who smoke in two health systems across the region. Compared with Whites, BIPOC populations in the US experience disproportionate health consequences from commercial cigarette use. Few evidence-based cessation treatments (EBCTs) have been specifically developed, evaluated, or implemented for BIPOC populations. Moreover, uptake of EBCT (e.g. medication, counseling) is lower among... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/12/2024
Locations: Hennepin Healthcare, Minneapolis, Minnesota +2 locations
Conditions: Tobacco Use Cessation, Cardiovascular Diseases, Tobacco Use, Smoking, Smoking Cessation
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Secondhand Tobacco Smoke and Cardiovascular Disease
NCT04715568
Recruiting
This is a double-blind randomized placebo-controlled crossover clinical trial of efficacy and safety of an FDA-approved angiotensin receptor blocker (losartan) to improve cardiopulmonary outcomes in individuals with pre-Chronic Obstructive Pulmonary Disease (COPD) due to prolonged exposure to secondhand tobacco smoke.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
07/11/2024
Locations: San Francisco Veterans' Affairs Medical Center, San Francisco, California
Conditions: Cardiovascular Diseases, Hypertension
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CARBON: UAB Cardiovascular Research Biobank
NCT05067231
Recruiting
The UAB Cardiovascular Research Biobank (CARBON) will be a resource that contains biological materials, such as DNA samples, in addition to health and personal information on a large number of people over time. It will be set up so that it can be used in the future as a resource for researchers undertaking a wide range of medical research.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/08/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Natriuretic Peptides, Cardiovascular Diseases, Hypertension, Diabetes, Obesity
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GENESIS: Genotype Guided - Natriuretic Peptides - Cardiometabolic Health Study
NCT05216042
Recruiting
Natriuretic Peptides (NP) are hormones produced by the heart, and they have a wide range of favorable metabolic benefits. Lower levels of these hormones are associated with an increased likelihood of the development of diabetes and poor cardiometabolic health. Obese and Black individuals have \~30% lower levels of NP and are at a greater risk of developing cardiovascular (CV) events as compared to lean and White counterparts. Some people have common genetic variations that cause them to have \~2... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/08/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Cardiovascular Diseases, Natriuretic Peptides, Cardiometabolic Diseases, Energy Expenditure, Glucose Metabolism, Exercise, Obesity
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NAUTICAL: Effect of Natriuretic Peptide Augmentation on Cardiometabolic Health in Black Individuals
NCT04055428
Recruiting
Black individuals are more likely to have decreased insulin sensitivity which results in a high risk for the development of cardiometabolic disease. The reasons for this are incompletely understood. Natriuretic peptides (NPs) are hormones produced by the heart that play a role in regulating the metabolic health of an individual. Low circulating level of NPs is an important contributor to increased risk for diabetes. The NP levels are relatively lower among Black individuals thus affecting their... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/08/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Diabetes Mellitus, Cardiovascular Diseases, Insulin Sensitivity/Resistance, Metabolic Disease, Natriuretic Peptides, Metabolism, Energy Expenditure
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Eliminating Severe Maternal Morbidity With Heart Health Doulas Trial
NCT05655936
Recruiting
This is a single site, single-blinded parallel randomized control trial that investigates a multi-level intervention to improve postpartum blood pressure in women with hypertensive disorder pregnancy. The investigators will recruit women diagnosed with a hypertensive disorder of pregnancy, identified between 3rd trimester and 2 weeks post-delivery. The investigators will randomize participants to receive usual care home blood pressure monitoring for 6 weeks versus an intervention of usual care +... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/08/2024
Locations: Magee Women's Hospital of UPMC, Pittsburgh, Pennsylvania
Conditions: Preeclampsia, Hypertensive Disorder of Pregnancy, Toxemia, Pregnancy Complications, Hypertension, Pregnancy-Induced, Hypertension, Obesity, Overweight, Nutrition Disorders, Vascular Diseases, Cardiovascular Diseases, Pre-Eclampsia, Eclampsia, Gestational Hypertension
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Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II
NCT06271577
Recruiting
AliveCor (www.alivecor.com) has developed several electrocardiogram (ECG) devices that interface with iOS and Android smartphones and tablets via various Kardia apps. The current Kardia family of devices can measure single lead and six limb-lead ECGs, depending on the device. KardiaMobile, KardiaMobile 6L, and KardiaMobile Card have FDA clearance for ECG rhythm recording. A modified single-lead Kardia smartphone 12-lead ECG was previously validated in the multicenter ST LEUIS study for the diagn... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/03/2024
Locations: Mayo Clinic, Rochester, Minnesota +1 locations
Conditions: Myocardial Infarction, Ischemia, Myocardial Ischemia, Heart Diseases, Cardiovascular Diseases, Vascular Diseases, Heart Attack, Heart Failure
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Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCT
NCT05288790
Recruiting
Among people living with HIV, heavy drinking increases the risk of heart disease and death. Studies suggest that alcohol changes the number and kind of bacteria in your gut and these changes increase the risk of heart disease and death. This randomized controlled trial will determine whether a pill containing healthy gut bacteria can increase the number good bacteria in the gut, lower levels of inflammation, and lower the risk of heart disease and death.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
06/27/2024
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Microtia, Dysbiosis, Alcohol Drinking, HIV Infections, Cardiovascular Diseases
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Text Education About Cardiovascular Health and HIV (TEACH-HIV)
NCT05642858
Recruiting
The overall objective is to evaluate the efficacy of educational text messages to reduce cardiovascular risk among persons living with HIV (PLWH).
Gender:
ALL
Ages:
40 years and above
Trial Updated:
06/17/2024
Locations: Zuckerberg San Francisco General Hospital, San Francisco, California +1 locations
Conditions: HIV, Human Immunodeficiency Virus, Cardiovascular Diseases, Atherosclerosis
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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
NCT04262206
Recruiting
PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the benefit of statins for reducing the primary composite of death, dementia, and persistent disability and secondary composites including mild cognitive impairment (MCI) and cardiovascular events.
Gender:
ALL
Ages:
75 years and above
Trial Updated:
06/14/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama +102 locations
Conditions: Cognitive Impairment, Mild, Dementia, Cardiovascular Diseases
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Triage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility
NCT06412536
Recruiting
SWIFT-CORE-101 is a single site survey study designed to assess potential participants' eligibility to screen for industry-sponsored clinical trials. A physician will oversee the informed consent process, after which participants will be surveyed on demographics, medical history, comorbidities, and current symptoms. Site staff may collect vital signs, urine drug screens, blood draws, and urine pregnancy tests. A doctor will review medical history with the participant to determine study suitabili... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/10/2024
Locations: Brooklyn Clinical Research, Brooklyn, New York
Conditions: Cardiovascular Diseases, Obesity, PreDiabetes, Diabetes Type 2, Metabolic Syndrome
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Cardiovascular Effects of a Healthy Dietary Pattern Containing Eggs
NCT06120400
Recruiting
This study will examine the effect of a healthy diet containing 2 eggs per day compared to a healthy diet containing 3 eggs per week on biomarkers of heart health after 4 weeks.
Gender:
ALL
Ages:
Between 30 years and 60 years
Trial Updated:
05/31/2024
Locations: The Pennylvania State University, University Park, Pennsylvania
Conditions: Cardiovascular Diseases
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