There are currently 196 active clinical trials seeking participants for Colorectal Cancer research studies. The states with the highest number of trials for Colorectal Cancer participants are California, Illinois, Ohio and New York.
Comparison of Contrast Agents in Liver MR for the Detection of Hepatic Metastases
Recruiting
If an abbreviated HBP protocol liver MR with gadobenate dimeglumine is shown clinically comparable to standard of care liver MR with gadoxetate disodium for detecting hepatic metastasis from colorectal cancer, its use will save time, cost, and patients' effort.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/11/2023
Locations: University of Colorado Hospital, Aurora, Colorado
Conditions: Oligometastatic Disease, Liver Metastases, Colorectal Cancer
A Study of Mental Health Care in People With Cancer
Recruiting
The purpose of this study is to look at mental health services for adults with depressed mood who were diagnosed with cancer at the age of 65 or older. This study will compare the usual approach for connecting older adults with depressed mood to mental health services with the Open Door for Cancer (OD-C) approach. We will find out if the OD-C approach is practical and useful for cancer patients who participate in the intervention and for providers who see or treat cancer patients.
Gender:
All
Ages:
65 years and above
Trial Updated:
09/08/2023
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Breast Cancer, Colorectal Cancer, Lung Cancer, Prostate Cancer
Engaging Black Men in Colorectal Cancer Screening
Recruiting
To determine the unmet needs, attitudes, barriers and facilitators of African American (AA)/ Black men use of colorectal cancer screening and describe how community leaders such as barbers may act as Community Champions to educate and facilitate screening participation.
Gender:
Male
Ages:
Between 45 years and 74 years
Trial Updated:
08/29/2023
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Colorectal Cancer, CRC, Behavior
Connecting Black Families in Houston, Texas to Hereditary Cancer Genetic Counseling, Genetic Testing, and Cascade Testing by Using a Simple Genetic Risk Screening Tool and Telegenetics
Recruiting
To identify Black individuals who are eligible for genetic testing through trusted community organizations, and to connect Black individuals and their families to genetic testing and counseling so that they can know their cancer risk and how to decrease it.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/14/2023
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Breast Cancer, Colorectal Cancer
A Study of the Possible Effects of Medication on Young Onset Colorectal Cancer (YOCRC)
Recruiting
This study will collect biospecimens (including blood, tissue, and stool samples) and health information to create a database-a type of collection of information-for better understanding young onset colorectal cancer (YOCRC). The study will include both people with YOCRC and healthy people.
Gender:
All
Ages:
Between 18 years and 49 years
Trial Updated:
08/08/2023
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Colorectal Cancer
Exercise Preconditioning With Cancer Surgeries
Recruiting
Studies have shown that people who are more physically fit prior to surgery do better after surgery. For this reason, it may be helpful for people who are going to have abdominal surgery for cancer to exercise before surgery to increase fitness. In this study, patients will be assigned to either maintain their current activity, or increase activity to 5 days a week, 40 minutes per day, of either continuous moderate activity or intervals of moderate and vigorous activity (three groups). All parti... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/02/2023
Locations: UVA Health System, Charlottesville, Virginia
Conditions: Colorectal Cancer, Hepatobiliary Cancer, Gynecologic Cancer
Shared Decision-making and Colorectal Cancer Screening
Recruiting
Conduct a feasibility pilot RCT of a newly developed colorectal cancer screening (CRC) decision aid (DA) including 66 LHL adults 76-85 years recruited from community health centers. Hypotheses: Patients in the intervention group will be more likely to change their intentions to be screened with fewer patients with <10 year LE and/or those with >10 year LE and no risk factors intending to be screened and more with >10 year LE and risk factors for CRC and/or those who have never been screened inte... Read More
Gender:
All
Ages:
Between 75 years and 85 years
Trial Updated:
07/20/2023
Locations: University of Pennsylvania Health System, Philadelphia, Pennsylvania
Conditions: Colorectal Cancer
Patient Outcomes After Hepatic Artery Infusion Pump Placement
Recruiting
The purpose of this study is to evaluate the surgical outcomes and the quality of life (QOL) in patients undergoing hepatic artery infusion pump placement for colorectal liver metastases (CRLM).
Gender:
All
Ages:
18 years and above
Trial Updated:
07/19/2023
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Colorectal Liver Metastases, Colorectal Cancer
Adoptive Cell Therapy Using Cancer Specific CD8+ Tumor Infiltrating Lymphocytes in Adult Patients With Solid Tumors
Recruiting
The subject of this study is the adoptive transfer of selected autologous tumor infiltrating lymphocytes (TIL) after in vitro expansion for the treatment of solid tumor malignancies. The TIL selection process is based on evidence showing that CD8+ TIL which co-express both CD39 and CD103 harbor the bulk of tumor-reactivity and that the remaining CD8 TIL is mainly composed of non-tumor reactive bystander cells. All of the expanded TIL that are produced (1-40 billion are expected) will be delivere... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/18/2023
Locations: Providence Portland Medical Center, Portland, Oregon
Conditions: HNSCC, Melanoma, Gynecologic Cancer, Colorectal Cancer, Lung Cancer, Urogenital Cancer
Individualized Dose Escalation of 5-FU for Gastrointestinal Cancer
Recruiting
This is a single-arm clinical trial that will evaluate the feasibility of a chemotherapy regimen adaptive, individualized dose escalation of 5-FU chemotherapy for patients who have good tolerance of the initial dose. Study participants will also receive oxaliplatin chemotherapy together with 5-FU, at standard doses. The goal of the study is to examine the feasibility and effectiveness of this approach, using individualized dose escalation of 5-FU in patients who do not have serious side effects... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/14/2023
Locations: Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: Colorectal Cancer, Esophagus Cancer, Appendix Cancer, Small Bowel Cancer, Ampullary Cancer
Comparing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) Using Mitomycin-C Versus Melphalan for Colorectal Peritoneal Carcinomatosis
Recruiting
The purpose of this trial is to compare the morbidity and mortality of CRS-HIPEC using mitomycin-C versus melphalan for colorectal peritoneal carcinomatosis. Morbidity and mortality will measured using the Comprehensive Complication Index (CCI) score, Common terminology criteria for adverse events (CTCAE version 4.03), and the Clavien-Dindo Classification.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
06/07/2023
Locations: The University of Kansas Medical Center, Westwood, Kansas
Conditions: Cancer, Appendiceal, ColoRectal Cancer
GCC19CART for Patients With Metastatic Colorectal Cancer
Recruiting
Study ICT-GCC19CART-US-001 (CARAPIA-1) is a Phase 1 study evaluating the safety, tolerability, clinical activity, pharmacokinetics and pharmacodynamics of GCC19CART in subjects with relapsed or refractory metastatic colorectal cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/02/2023
Locations: City of Hope Comprehensive Cancer Center, Duarte, California +5 locations
Conditions: Colorectal Cancer