There are currently 79 active clinical trials seeking participants for Cystic Fibrosis research studies. The states with the highest number of trials for Cystic Fibrosis participants are Ohio, California, New York and Florida.
Health Outcomes of Parents With Cystic Fibrosis
NCT05829694
Recruiting
This project will determine the health impact of parenthood on people with cystic fibrosis (CF). The study team will use retrospective data to provide relatively immediate evidence on parenthood's effect on pulmonary health.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/02/2024
Locations: National Jewish Health, Denver, Colorado +7 locations
Conditions: Cystic Fibrosis, Parenthood Status
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Non-pulmonary Contributors of Exercise Intolerance in Patients With Cystic Fibrosis
NCT04166396
Recruiting
The purpose of this research study is to examine if the use of antioxidant supplements impacts exercise intolerance in people with CF.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/25/2024
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Cystic Fibrosis
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Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study
NCT05548283
Recruiting
The purpose of this study is to look at pulmonary exacerbations in people with cystic fibrosis (CF) that need to be treated with antibiotics given through a tube inserted into a vein (intravenous or IV). A pulmonary exacerbation is a worsening of respiratory symptoms in people with CF that needs medical intervention. Both doctors and CF patients are trying to understand the best way to treat pulmonary exacerbations. This study is trying to answer the following questions about treating a pulmonar... Read More
Gender:
All
Ages:
6 years and above
Trial Updated:
04/24/2024
Locations: The Children's Hospital Alabama, University of Alabama at Birmingham, Birmingham, Alabama +60 locations
Conditions: Cystic Fibrosis, Cystic Fibrosis Pulmonary Exacerbation
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At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions
NCT01931644
Recruiting
We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research. We make it easy for patients to contribute to research for medical conditions that matter most to them, regardless of their location or ability to travel.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
04/15/2024
Locations: Sanguine Biosciences, Los Angeles, California
Conditions: All Diagnosed Health Conditions, ADD/ADHD, Alopecia Areata, Ankylosing Spondylitis, Asthma, Atopic Dermatitis Eczema, Beta Thalassemia, Bipolar Disorder, Breast Cancer, Celiac Disease, Cervical Cancer, Chronic Inflammatory Demyelinating Polyneuropathy, Chronic Kidney Diseases, Chronic Obstructive Pulmonary Disease, Colon Cancer, Colorectal Cancer, Crohn's Disease, Cystic Fibrosis, Depression, Diabetes Mellitus, Duchenne Muscular Dystrophy, Endometriosis, Epilepsy, Facioscapulohumeral Muscular Dystrophy, G6PD Deficiency, General Anxiety Disorder, Hepatitis B, Hereditary Hemorrhagic Telangiectasia, HIV/AIDS, Human Papilloma Virus, Huntington's Disease, Idiopathic Thrombocytopenic Purpura, Insomnia, Kidney Cancer, Leukemia, Lung Cancer, Lupus Nephritis, Lymphoma, Melanoma, Multiple Myeloma, Multiple Sclerosis, Myositis, Myotonic Dystrophy, Ovarian Cancer, Pancreatic Cancer, Parkinson's Disease, Polycystic Kidney Diseases, Prostate Cancer, Psoriasis, Psoriatic Arthritis, Rosacea, Scleroderma, Sickle Cell Anemia, Sickle Cell Trait, Sjogren's Syndrome, Skin Cancer, Spinal Muscular Atrophy, Systemic Lupus Erythematosus, Thrombotic Thrombocytopenic Purpura, Trisomy 21, Ulcerative Colitis
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Skeletal Health and Bone Marrow Composition in Adolescents With Cystic Fibrosis
NCT06216704
Recruiting
The investigators will be evaluating bone marrow composition via magnetic resonance imaging in adolescents diagnosed with cystic fibrosis (CF) compared to healthy, matched controls. The investigators will also be assessing their bone mineral density via other imaging modalities, including dual-energy X-ray absorptiometry (DXA) and peripheral quantitative computed tomography (pQCT). This longitudinal project will focus on abnormalities in bone marrow composition, and specifically whether adolesce... Read More
Gender:
All
Ages:
Between 13 years and 20 years
Trial Updated:
04/11/2024
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Cystic Fibrosis
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The Effects of a Low Glycemic Load Diet on Dysglycemia and Body Composition in Adults With Cystic Fibrosis-Related Diabetes
NCT05723445
Recruiting
This study will evalute the effect of a low glycemic load (LGL diet on dysglycemia, insulin requirements, DXA-derived body composition, gastrointestinal symptoms and quality of life measures in adults with cystic fibrosis-related diabetes (CFRD). We will use continuous glucose monitors (CGM) to assess the LGL diet both in a controlled setting (via a meal delivery company) and in free-living conditions.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
04/09/2024
Locations: Boston Children's Hospital, Boston, Massachusetts +1 locations
Conditions: Cystic Fibrosis, Cystic Fibrosis-related Diabetes, Cystic Fibrosis With Intestinal Manifestations
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Markers of Osteoporosis in Cystic Fibrosis
NCT03921060
Recruiting
Main Study Up to 100 subjects, both non-CF volunteers and Cystic Fibrosis (CF) patients, will participate in a single study visit that will include a DEXA scan, micro CT, and blood collection. Denosumab (Prolia) Sub study Approximately 10 adult subjects with CF who participated in the main study and have results indicating bone disease will receive treatment with Denosumab for up to 5 years. They will be asked to return annually for repeat DEXA scans, micro CT, and blood collection.
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
04/08/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Cystic Fibrosis
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STaph Aureus Resistance-Treat Early and Repeat (STAR-TER)
NCT03489629
Recruiting
To evaluate the micro-biologic efficacy and safety of a streamlined treatment for early onset methicillin-resistant staphylococcus aureus (MRSA) in patients with cystic fibrosis.
Gender:
All
Ages:
Between 2 years and 45 years
Trial Updated:
04/08/2024
Locations: National Jewish Health, Denver, Colorado +8 locations
Conditions: Cystic Fibrosis
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A Study Assessing KB407 for the Treatment of Cystic Fibrosis
NCT05504837
Recruiting
This study will evaluate safety and tolerability of ascending doses of nebulized KB407 in adults with cystic fibrosis.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/08/2024
Locations: Yale University School of Medicine, New Haven, Connecticut +1 locations
Conditions: Cystic Fibrosis
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A Pilot and Feasibility Study to Evaluate High vs Low Glycemic Index Mixed Meal Tolerance Test in Adolescents and Young Adults With Cystic Fibrosis
NCT06350149
Recruiting
The goal of this study is to determine the extent to which excess dietary simple sugars serve as a secondary mediating factor in Cystic fibrosis-related diabetes (CFRD) development. The main questions it aims to answer are: Whether conducting a randomized 2x2 factorial design that evaluates acute postprandial changes in glucose over 2 hours following ingestion of a mixed meal challenge that varies by glycemic index and consumption of a sugar-sweetened beverage is acceptable and feasible. What a... Read More
Gender:
All
Ages:
Between 12 years and 21 years
Trial Updated:
04/04/2024
Locations: Center for Advanced Pediatrics: Emory Healthcare, Atlanta, Georgia
Conditions: Cystic Fibrosis
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Trikafta in Cystic Fibrosis Patients
NCT03506061
Recruiting
This clinical study will enroll 42 participants without the F508del mutation, carrying partial function or N1303K mutations not approved for Trikafta, and who are not expected to be approved for CFTR modulator treatment in the immediate future. Each participant will be given Trikafta for approximately four weeks. The study researchers will monitor clinical endpoints that include forced expiratory volume (FEV1) and sweat chloride. Additionally, the researchers will obtain skin biopsy material and... Read More
Gender:
All
Ages:
12 years and above
Trial Updated:
03/28/2024
Locations: University of Alabama Cystic Fibrosis Research Center, Birmingham, Alabama +2 locations
Conditions: Cystic Fibrosis
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Project 2 Airway Potential Hydrogen (pH) in Asthma
NCT03617718
Recruiting
This study is testing a non invasive way to measure airway pH in individuals with Asthma and Cystic Fibrosis using a new inhaled drug. The airway pH will help health care providers in creating tailored treatment plans for individuals suffering from these specific conditions.
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
03/13/2024
Locations: Indiana University School of Medicine, Indianapolis, Indiana +1 locations
Conditions: Cystic Fibrosis, Asthma, Severe Persistent Asthma, Healthy
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