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Cystic Fibrosis Clinical Trials
A listing of 79 Cystic Fibrosis clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
49 - 60 of 79
There are currently 79 active clinical trials seeking participants for Cystic Fibrosis research studies. The states with the highest number of trials for Cystic Fibrosis participants are Ohio, California, New York and Florida.
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Chronic Cough Clinical Study
Recruiting
We are evaluating an investigational treatment to see if it may help people dealing with chronic cough.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required. If you qualify, you may receive:
Payment up to $1500, which varies by study.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required. If you qualify, you may receive:
Payment up to $1500, which varies by study.
Conditions:
Cough
Chronic Cough
Asthma
Allergic Asthma
Sinusitis
Featured Trial
Healthy Volunteer Trials
Recruiting
Healthy trials near you are looking for participants to help push medical research forward. Click through to learn more!
Conditions:
Healthy
Featured Trial
Healthy Volunteer Clinical Studies
Recruiting
Find a study looking for volunteers at a study site near you! Some trials offer compensation for time and travel. Click through to learn more about study opportunities.
Conditions:
Healthy
Healthy Volunteers
Feasibility of a New Model for Exercise Prescription in Cystic Fibrosis
Recruiting
The purpose of this protocol is to begin an exercise program combined with behavioral counseling for patients who are hospitalized with a cystic fibrosis exacerbation. The exercise program will begin during the hospital stay. Beginning an exercise program during this period of reduced mobility and isolation may be an ideal time to deliver a structured exercise prescription along with a behavioral program to promote long-term adherence to exercise (structured physical activity) . Hospitalized pat... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/07/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Cystic Fibrosis
Novel Therapeutic Approaches for Treatment of CF Patients With W1282X Premature Termination Codon Mutations
Recruiting
Based on previous clinical findings, the investigator hypothesize that ivacaftor will have synergistic effects with drugs that facilitate truncated but partially active W1282X CFTR protein processing (tezacaftor) in patients with W1282X CFTR. In the current study, the investigators propose to directly test the efficacy of tezacaftor/ivacaftor (TEZ/IVA) and Trikafta for W1282X CFTR therapy in the clinic in comparison to ivacaftor alone.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/06/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Cystic Fibrosis
High Resolution Micro OCT Imaging
Recruiting
The purpose of this study is to learn about using the imaging to make images of the lungs and nose with the long-term goal of the research leading to potential treatments and new therapies for patients with cystic fibrosis.
Gender:
All
Ages:
14 years and above
Trial Updated:
12/06/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Cystic Fibrosis, COPD, PCD - Primary Ciliary Dyskinesia, Covid19, Sinusitis
Lung Transplant READY CF 2: A Multi-site RCT
Recruiting
Lung transplant is an option for treating end-stage lung disease in cystic fibrosis (CF). In the United States, more people with CF and low lung function die each year than undergo lung transplant. More than half of people with CF who die without a lung transplant were never referred for consideration. Patient preference not to undergo lung transplant may account for 25-40% of decisions to defer referral. Rates of death without transplant are higher for people with CF who are members of marginal... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/04/2023
Locations: University of California at Los Angeles (UCLA), Los Angeles, California +8 locations
Conditions: Cystic Fibrosis
Improving P. Aeruginosa Detection With Breath-based Diagnostics (IMPACT-Breath)
Recruiting
The study is a breath biomarker validation study. It is anticipated that 300 patients with cystic fibrosis (CF) from 5 clinical sites in the USA will be enrolled. The study is funded by the US NIH and the US Cystic Fibrosis Foundation. Enrollment commenced in May 2019. Sputum, induced sputum, and oropharyngeal swabs will be collected and evaluated at each clinic as part of standard clinical practice. Excess sputum will be sent to Children's Colorado Hospital for molecular analysis. No swabs will... Read More
Gender:
All
Ages:
3 years and above
Trial Updated:
12/02/2023
Locations: Phoenix Children's Hospital, Phoenix, Arizona +6 locations
Conditions: Cystic Fibrosis
Impact of Highly Effective Modulator Therapy on the Cystic Fibrosis Microbiome
Recruiting
The goal of this observational study is to learn about the effects of a specific cystic fibrosis therapy (Cystic Fibrosis Transmembrane Conductance Regulator Modulator Therapy) on chronic sinonasal disease. The main questions it aims to answer are:
How does this therapy impact bacterial communities in the paranasal sinuses?
How does this therapy impact inflammation in the paranasal sinuses and olfactory cleft?
How does this therapy impact sense of smell and sinonasal disease burden in individua... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
11/29/2023
Locations: Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: Cystic Fibrosis
Estrogen Supplementation and Bone Health in Women With CF
Recruiting
The goal of this study is to learn about the role of estrogen and other hormones in bone development in adolescent and young adult women with cystic fibrosis (CF). The study has two main components, an observational study and a feasibility sub-study. The main questions it aims to answer are:
How do different forms of hormonal contraception (e.g. birth control pill or other progesterone only methods) impact bone health?
Is a study of transdermal estradiol (estrogen skin patches) feasible in this... Read More
Gender:
Female
Ages:
Between 0 years and 100 years
Trial Updated:
11/21/2023
Locations: Johns Hopkins, Baltimore, Maryland
Conditions: Cystic Fibrosis, Hypoestrogenism
CHaractErizing CFTR Modulated Changes in Sweat Chloride and Their Association With Clinical Outcomes
Recruiting
This is a multicenter, cross-sectional, cohort study which will collect contemporary sweat chloride (SC) values from approximately 5000 Cystic Fibrosis (CF) patients prescribed and currently receiving commercially approved Cystic Fibrosis transmembrane conductance regulator (CFTR) modulator therapies.
Gender:
All
Ages:
4 months and above
Trial Updated:
11/21/2023
Locations: The Children's Hospital Alabama, University of Alabama at Birmingham, Birmingham, Alabama +51 locations
Conditions: Cystic Fibrosis
Role of Body Fat Distribution in Metabolic and Pulmonary Decline in Cystic Fibrosis (ORBIT-CF)
Recruiting
Nutrition and body composition, the amount of muscle and fat in the body, has a role in overall health. This study wants to learn more about how nutrition and body composition affects health outcomes like glucose tolerance and lung function in patients with cystic fibrosis (CF) who are ages 16-30 years old. 60 adolescents and young adults with CF will be recruited, and 30 volunteers without cystic fibrosis. A total of 40 of these study participants with CF will be asked to return for annual stud... Read More
Gender:
All
Ages:
16 years and above
Trial Updated:
10/25/2023
Locations: University of Alabama at Birmingham (UAB)/Children's of Alabama, Birmingham, Alabama +1 locations
Conditions: Cystic Fibrosis
BEGIN Novel ImagiNG Biomarkers
Recruiting
To determine the treatment effect of triple-combination therapy in 6-8 year olds after presumed FDA approval, using rapid structural and functional pulmonary and abdominal MRI (UTE and 129Xe).
Gender:
All
Ages:
Between 6 years and 8 years
Trial Updated:
10/23/2023
Locations: University of Kansas Medical Center, Kansas City, Kansas +2 locations
Conditions: Cystic Fibrosis
Pulmonary Vascular Disease in CF
Recruiting
In this project, the investigators seek to understand the role of endothelial cells in Cystic Fibrosis (CF) lung disease. This objective will be achieved by conducting a cross sectional clinical study to define the morphology of the pulmonary circulation across a range of lung function coupled with a mechanistic study of the effect of dysfunctional cystic fibrosis transmembrane conductance regulator (CFTR) in endothelial cells on vasculogenesis, epithelial morphogenesis and epithelial CFTR funct... Read More
Gender:
All
Ages:
Between 5 years and 21 years
Trial Updated:
10/23/2023
Locations: Riley Hospital for Children, Indianapolis, Indiana +1 locations
Conditions: Cystic Fibrosis
Impact of Sinus Surgery on Individuals With Cystic Fibrosis
Recruiting
This study will be a prospective, observational study of patients who undergo endoscopic sinus surgery for cystic fibrosis-related chronic rhinosinusitis (CRS). Individuals who do not undergo surgery but are treated medically for CRS will also be enrolled to serve as a control group. Outcomes analyzed will include pulmonary, quality of life, and others.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
09/29/2023
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Chronic Rhinosinusitis (Diagnosis), Cystic Fibrosis
49 - 60 of 79