There are currently 21 active clinical trials seeking participants for Degenerative Disc Disease research studies. The states with the highest number of trials for Degenerative Disc Disease participants are California, Texas, Florida and North Carolina.
Trial for Treating Painful Degenerative Disc Disease
NCT05287867
Recruiting
To evaluate and compare two platelet-based treatments of the functional spinal unit spaced 4 weeks apart to sham procedures for the treatment of degenerative disc disease.
Gender:
All
Ages:
Between 25 years and 65 years
Trial Updated:
09/25/2023
Locations: Centeno-Schultz Clinic, Broomfield, Colorado +1 locations
Conditions: Degenerative Disc Disease
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OSTEOAMP Lumbar Fusion Intra-Patient Controlled Study
NCT05405374
Recruiting
The objective of this clinical study is to compare OSTEOAMP SELECT Fibers to Infuse Bone Graft, in terms of effectiveness and safety, when used as a bone graft substitute in in skeletally mature patients qualified for 2-lumbar interbody fusion (LIF) by means of an intra-patient control model.
Gender:
All
Ages:
Between 21 years and 80 years
Trial Updated:
08/25/2023
Locations: Yale University, New Haven, Connecticut +8 locations
Conditions: Lumbar Spine Disease, Lumbar Spondylolisthesis, Lumbar Spine Instability, Lumbar Spondylosis, Degenerative Disc Disease
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Anterior Cervical Disectomy And Fusion Using The Tritanium® C Anterior Cervical Cage For One Or Two-Levels
NCT04214535
Recruiting
This is a prospective, single arm clinical study to evaluate fusion status and patient reported outcomes utilizing the Stryker Tritanium® C Anterior Cervical interbody device at one or two contiguous levels. Subjects that are recommended for surgical treatment of either a 1- or 2-level ACDF (Anterior Cervical Discectomy and Fusion) between the levels of Cervical Spine 2 to Thoracic 1 (C2-T1) and diagnosed with degenerative disc disease will be screened for the study.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/11/2023
Locations: William Beaumont Hospital, Royal Oak, Michigan
Conditions: Cervical Disc Herniation, Cervical Disc Degeneration, Degenerative Disc Disease
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Investigation of DEXA-C Anterior Cervical Interbody System
NCT05883436
Recruiting
FDA Cleared interbody product for the cervical spine, designed to match a patients DEXA scan for increase in fusion rate.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/30/2023
Locations: UCI Center for Clinical Research, Orange, California +1 locations
Conditions: Degenerative Disc Disease
Register for Updates
ACDF Using Structural Allograft vs. Tritanium C
NCT04388332
Recruiting
This is an observational, descriptive, prospective and retrospective data collection study. The purpose of this study is to observe radiographic outcomes of patients who will undergo anterior cervical discectomy and fusion (ACDF) utilizing Tritanium C (Stryker Spine). The rate of fusion success and adverse events will be compared retrospectively to patients who underwent instrumented ACDF utilizing structural allograft bone with plates.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/07/2023
Locations: Allegheny Health Network, Pittsburgh, Pennsylvania
Conditions: Degenerative Disc Disease
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Comparative Analysis of Virtuous and Autograft in Lumbar Fusion
NCT05614284
Recruiting
Compare the lumbar fusion rates at 12 and 24 months when lumbar arthrodesis is performed using Virtuous or Autograft Bone Graft. Surgical approach is limited to TLIF (MIS or Open) with posterior fixation and supplemental posterolateral fusion as directed by physician, but must comply with FDA approved/cleared indication for use and labeling.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/10/2022
Locations: Michigan Brain and Spine, Royal Oak, Michigan
Conditions: Degenerative Disc Disease
Register for Updates
Interbody Systems: Post Market Clinical Follow-up Study
NCT04911257
Recruiting
This is a prospective, multi-center study of subjects who will undergo spinal fusion surgery utilizing Stryker Interbody Systems that require post market clinical follow up (PMCF). The primary study hypothesis for each system is that the mean change in NDI (cervical) or ODI (lumbar) from baseline to Month 12 < -10, that is, the mean improvement exceeds 10 points. In supporting analysis, the same hypotheses will be tested for mean change from baseline to 24 months to demonstrate durability of ef... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/09/2022
Locations: Spine Institute of Louisiana Foundation, Inc., Shreveport, Louisiana +1 locations
Conditions: Degenerative Disc Disease
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OssiMend BA in Posterolateral Instrumented Lumbar Fusion
NCT04775537
Recruiting
The primary objective of this study is to measure the success rate of lumbar fusion in subjects at 12 months when instrumented lumbar arthrodesis is performed using OssiMend Bioactive Moldable as the bone grafting material
Gender:
All
Ages:
18 years and above
Trial Updated:
03/08/2022
Locations: McKenzie-willamette Medical Center, Eugene, Oregon
Conditions: Spinal Disease, Degenerative Disc Disease
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Clinical and Radiographic Outcomes of TLIF w/3D Printed Cellular Implant
NCT05023733
Recruiting
This study is designed to evaluate clinical outcomes and spine fusion rates for patients undergoing transforaminal lumbar interbody fusion using the CONDUIT 3D printed titanium TLIF cage.
Gender:
All
Ages:
Between 35 years and 80 years
Trial Updated:
01/14/2022
Locations: Hartford Healthcare Bone and Joint Institute, Hartford, Connecticut
Conditions: Foraminal Stenosis, Degenerative Disc Disease, Lumbar Spondylolisthesis, Lumbar Spinal Stenosis
Register for Updates