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Dry Eye Clinical Trials
A listing of 11 Dry Eye clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 11 of 11
There are currently 11 active clinical trials seeking participants for Dry Eye research studies. The states with the highest number of trials for Dry Eye participants are California, Florida, Tennessee and Massachusetts.
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Chronic Cough Research Study
Recruiting
Are you tired of living with chronic cough? Our research study is now looking to enroll people from all backgrounds to help research potential new treatment options for chronic cough.
You are under no obligation to take part and health insurance is not required. Find out more today! We’d love to hear from you!
You are under no obligation to take part and health insurance is not required. Find out more today! We’d love to hear from you!
Conditions:
Chronic Cough
Refractory or Unexplained Chronic Cough
Cough
Asthma
Sinusitis
Featured Offer
Lose Weight with GLP-1 Medications
Recruiting
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GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.
As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.
GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.
As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.
Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
Featured Trial
Stroke Clinical Study
Recruiting
A clinical study for people that suffer with Stroke
Conditions:
Stroke
A Study in the Treatment of Mild to Moderate Dry Eye Disease Comparing Saline to TTAX03.
Recruiting
The purpose of this randomized, controlled, multicenter study is to evaluate the safety and efficacy of TTAX03 in participants with mild to moderate DED.
The primary question it aims to answer is if TTAX03 is safe. The secondary is the effectiveness.
Researchers will compare 10mg of TTAX03 reconstituted in 150, 300, or 600 uL saline to the saline control group to look at effectiveness.
Participants will be randomized to a treatment group one time and be evaluated at 5 different study visits.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/22/2025
Locations: University California Berkeley, Berkeley, California +8 locations
Conditions: Dry Eye, Dry Eye Disease (DED), Dry Eye Disease With Severe Keratitis
A Study to Evaluate Concomitant Perfluorohexyloctane Use With Contact Lens Wear
Recruiting
Assess the impact of concomitant Miebo use while wearing contact lenses
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/12/2025
Locations: Site 101, San Diego, California +7 locations
Conditions: Dry Eye
Quality of Life in Presbyopic Patients Who Are Treated With Qlosi
Recruiting
The goal of this clinical trial is to determine how Qlosi™ (pilocarpine HCL ophthalmic solution) 0.4%impacts the quality of life of participants with presbyopia by using a battery of validated and investigator-developed instruments
* Improvement in presbyopic symptoms as measured with the Near Activity Visual Questionnaire-Presbyopia (NAVQ-P) when using Qlosi™ at week 4 compared to baseline (continuous variable).
* Improvement in presbyopic symptoms as measured with the Visual Quality of Life w... Read More
Gender:
ALL
Ages:
Between 45 years and 64 years
Trial Updated:
08/02/2025
Locations: Complete Eye Care of Medina, Medina, Minnesota +1 locations
Conditions: Presbyopia, Glasses, Dry Eye
Performance of Systane PRO Versus Refresh Optive Mega-3
Recruiting
Single site, prospective, double-masked, randomized-controlled, cross-over study of the subjective and objective performance of 2 different eyedrops. Subjects will be assessed at a screening visit, and 3 follow-up visits. Clinical evaluations will include patient questionnaires.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
06/18/2025
Locations: Scripps Poway Eyecare & Optometry, San Diego, California
Conditions: Dry Eye
Use of Acthar Gel Single-Dose Pre-Filled SelfJectTM Injector in Patients With Moderate-Severe Keratitis and Autoimmune Disease
Recruiting
Single-site, open label pilot study of 20 autoimmune patients diagnosed with dry eye demonstrating via the proparacaine challenge some peripheral corneal pain component. At least 16 patients will receive and complete 12 weeks of 80 units of Acthar Gel to be injected subcutaneously twice weekly via Acthar Gel single-dose pre-filled SelfJectTM injector (SelfJect) to assess the effects on subjective sensation of ocular pain, conjunctival and corneal staining, in vivo assessments of corneal nerves a... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
05/08/2025
Locations: Toyos Clinic, Nashville, Tennessee
Conditions: Autoimmune Diseases, Dry Eye, Neurotrophic Keratitis
Predicting the Success of Dry Eye Disease Interventions Using Clinical Tests
Recruiting
This is a single site, prospective, cross-sectional, controlled clinical study on a total of 66 subjects. The subjects are divided into two groups: Hypertonic Saline Non-Responders (33 subjects) and Hypertonic Saline Responders (33 subjects). After completion of questionnaires, the subjects will undergo Dry Eye Disease testing and functional nerve testing. Subjects who qualify will be dispensed 4 weeks of preservative free artificial tears and instructed to instill one drop into each eye twice d... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/24/2025
Locations: Tufts Medical Center-New England Eye Center, Boston, Massachusetts
Conditions: Dry Eye
The THINK Study Incidence of Neurotrophic Keratopathy)
Recruiting
The study purpose is to evaluate corneal sensitivity in patients that have Stage 1 Neurotrphic Keratopathy (NK). Identifying patients with Stage 1 NK, may predict those who will in the future require rhNGF for optimal visual performance.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/25/2024
Locations: Harvard Eye Associates, Laguna Beach, California
Conditions: Dry Eye
A Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye
Recruiting
The purpose of this study is to determine the safety and efficacy of VSJ-110 compared to placebo in the treatment of dry eye.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/05/2024
Locations: Vanda Investigational Site, Andover, Massachusetts
Conditions: Dry Eye
Evaluating Impact of Systane iLux on Dryness Symptoms and Wearing Time in Contact Lens Users
Recruiting
To evaluate dry eye symptoms and contact lens wearing times after a single iLux treatment by evaluating change from baseline in OSDI scores, subjective CLDEQ8 and CL wearing time questionnaires, and meibomian gland secretion scores.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/14/2023
Locations: Periman Eye Institute, Seattle, Washington
Conditions: Meibomian Gland Dysfunction, Dry Eye
TearCare System to Treat Dry Eye Disease
Recruiting
In this study, the TearCare System will be compared with the LipiFlow Thermal Pulsation System in patients with dry eye disease. The objective is to demonstrate that the TearCare System is safe and effective in relieving the signs and symptoms of dry eye disease.
NOTE: All sites have been selected for this study. We are not seeking additional sites at this time.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
09/17/2019
Locations: Center for Excellence in Eye Care, Miami, Florida
Conditions: Dry Eye, Meibomian Gland Dysfunction
Study of the TearCare System in Dry Eye Disease
Recruiting
This study is being conducted to evaluate the short-term (1 month) safety and effectiveness of a single TearCare procedure to treat adult patients with dry eye disease.
NOTE: All sites have been selected for this study.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
08/15/2018
Locations: Eye Research Institute, Newport Beach, California +1 locations
Conditions: Dry Eye
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