There are currently 23 active clinical trials seeking participants for Dysphagia research studies. The states with the highest number of trials for Dysphagia participants are New York, Florida, Ontario and California.
Training Swallowing Initiation During Expiration
Recruiting
Head and neck cancers have escalated to epidemic levels in the United States, and survivors are suffering from life-long, devastating swallowing disorders with limited therapeutic options. This clinical trial investigates a novel swallowing treatment that trains initiation of swallowing during the expiratory phase of respiration to improve swallowing safety and efficiency.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/21/2025
Locations: Northwestern Memorial Hospital, Chicago, Illinois +1 locations
Conditions: Head and Neck Cancer, Dysphagia, Oropharyngeal Dysphagia, Oropharynx Squamous Cell Carcinoma
TEE and Dysphagia in Lung Transplantation
Recruiting
The primary outcome of this study is dysphagia (difficulty swallowing) on postoperative speech and swallow evaluation following lung transplantation. Transesophageal echocardiography (TEE) (creates pictures of the heart from inside the participants body) is routinely performed for all lung transplantations at the University of California, Los Angeles (UCLA) and it is the standard of care. Patients are randomized to two groups. The intervention group would limit the number of TEE clips (# pictur... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/16/2025
Locations: Ronald Reagan UCLA Medical Center, Department of Anesthesiology & Perioperative Medicine, Los Angeles, California
Conditions: Lung Transplant, Dysphagia
Wearable Biofeedback for Swallowing Disorders Rehabilitation in Stroke and Parkinson Disease
Recruiting
Dysphagia, or difficulty swallowing, is a common symptom of many neurological diseases but its treatment is not well established or easily accessible. To start addressing this gap, the researchers developed and validated a cost-effective wearable surface electromyography (sEMG) biofeedback sensor technology (i-Phagia), optimized to record muscle activity from the head/neck and provide biofeedback to patients and adherence data to clinicians during swallow therapy. This system has been developed... Read More
Gender:
ALL
Ages:
Between 50 years and 90 years
Trial Updated:
07/09/2025
Locations: Purdue University, West Lafayette, Indiana
Conditions: Dysphagia, Stroke, Parkinson Disease
A Digital Therapeutic Platform for Swallowing and Drooling Problems in Parkinson's
Recruiting
The purpose of this study is the development and early-stage validation of a wearable sensor for dysphagia in patients with PD.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
07/08/2025
Locations: Northwestern University, Evanston, Illinois
Conditions: Dysphagia, Parkinson Disease
Swallowing Impairments in Adults With and Without Alzheimer's Disease
Recruiting
This research study is investigating whether people with Alzheimer's disease (AD) experience more changes to swallowing than their healthy age-matched peers. The prevalence of swallowing impairments in moderate-severe AD is high (85-93%), yet little is known about how swallow function evolves throughout the disease course in people with AD. The overall objective of this study is to evaluate swallowing function in adults with and without Alzheimer's disease. The investigator will also be involvin... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
06/17/2025
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Alzheimer Disease, Caregiver Burden, Healthy Aging, Dysphagia
Family Caregiver Online Survey (Dementia and Swallowing Difficulties)
Recruiting
The Family Caregiver Survey is a one-time, 30-minute, online survey for people living with and caring for a family member with dementia. The goal of this research is to explore the needs of family caregivers, specifically when it comes to managing swallowing difficulties (dysphagia).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/12/2025
Locations: Remote study offered by the University of Oregon, Eugene, Oregon
Conditions: Dementia, Dysphagia, Dementia Alzheimers, Dementia, Vascular, Dementia, Mixed, Dementia With Lewy Bodies, Dementia Frontal, Dementia, Mild, Dementia Moderate, Dementia Severe, Parkinson Disease Dementia, Dementia Frontotemporal
Respiratory Strength Training in Heart Transplant Recipients
Recruiting
This research study is investigating whether completing breathing exercises before surgery helps heart transplant patients recover after surgery. Previous studies have shown that breathing exercises can improve breathing, cough, and swallow function in patients with other diseases/conditions. The current study will investigate the impact of a preoperative respiratory muscle strength training program on breathing and cough function, swallow function, patient-reported eating and swallowing fatigue... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
05/26/2025
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Dysphagia, Heart Transplant Recipients
Interventions for Patients With Alzheimer's Disease and Dysphagia
Recruiting
The overall purpose of this project is to develop effective dysphagia rehabilitative interventions for patients with Alzheimer's Disease and related dementias at risk for pneumonia development.
Gender:
ALL
Ages:
Between 50 years and 99 years
Trial Updated:
05/20/2025
Locations: University of Wisconsin-Madison, Madison, Wisconsin
Conditions: Dementia, Dysphagia, Alzheimer Disease
External Pharyngeal Exerciser and Dysphagia
Recruiting
The goal of this a clinical trial is to test the effect of a pharyngeal exerciser in rehabilitation of pharyngeal phase of swallowing in patients with dysphagia. The main question it aims to answer is: •Does application of pharyngeal exerciser improve swallowing as evidenced by need for prescribed intervention for dysphagia (maneuvers, exercises or dietary modification to prevent aspiration). Participants will: * Perform barium swallows in lateral view fluoroscopy * Over a six-week period, pe... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/25/2025
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Dysphagia
Establishing Pressures at the EGJ During Diaphragmatic Breathing Using High-resolution Esophageal Manometry
Recruiting
The goal of this study is to determine which position, maneuvers or combination thereof generates the highest pressure at the EGJ as assessed by high-resolution esophageal manometry and thus greater or more robust contraction of the diaphragm.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/14/2025
Locations: Mayo Clinic, Jacksonville, Florida
Conditions: Gastroesophageal Reflux, Dysphagia, Esophageal Motility Disorders
Anterior Cervical Discectomy and Fusion (ACDF) - Behavioral Intervention
Recruiting
This study will prospectively recruit and enroll patients undergoing primary Anterior Cervical Discectomy and Fusion (ACDF) surgeries at NYU Langone. Participants will undergo pre-operative and six-week post-operative swallowing assessment using videofluoroscopy (VFSS). Acoustic voice samples and Patient Reported Outcome Measures (PROMs) for swallowing and voice will also be collected. Beginning one-week before surgery participants will begin a behavioral health program that will be continued fo... Read More
Gender:
ALL
Ages:
Between 21 years and 99 years
Trial Updated:
04/11/2025
Locations: NYU Langone Health, New York, New York
Conditions: Dysphagia
Usefulness and Feasibility of Ultrasound in Office Laryngology Procedures
Recruiting
Investigators will assess the usefulness of using ultrasound in office procedures for laryngology interventions. Participants who qualify will be adults who are undergoing superior laryngeal nerve block, injection laryngoplasty, swallowing evaluation, voice evaluation and voice therapy.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
04/04/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Cough, Vocal Cord Atrophy, Vocal Cord Paresis, Vocal Cord Paralysis, Dysphagia, Dysphonia