There are currently 10 active clinical trials seeking participants for Gastroesophageal Reflux research studies. The states with the highest number of trials for Autism participants are California, Florida, Ontario and New York.
External UES Band (Shaker Pressure Band) and GERD
Recruiting
This protocol is a study to assess the efficacy of an external upper esophageal band to decrease subjective nighttime symptoms related to esophageal reflux into the pharynx.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
03/19/2024
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Gastroesophageal Reflux
Gracie Diet for Gastroesophageal Reflux Disease
Recruiting
GERD, is a common and chronic world-wide disease. Cardinal symptoms of this condition are heartburn-regurgitation, and sometimes with extra-intestinal symptoms that can affect patients' quality of life. Proton pump inhibitors (PPIs) potently inhibit gastric acid secretion and are widely used for treatment of acid-related diseases. This class of medications is the most widely used for the management of GERD. H2 Receptor Antagonists (H2RAs) are another type of medication used to of uncomplicated G... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
03/15/2024
Locations: Johns Hopkins Bayview Medical Center, Baltimore, Maryland
Conditions: Gastroesophageal Reflux, GERD
Multi-Center Study of Panosyl-Isomaltooligosaccharides Adjunctive to PPI Therapy to Treat GERD
Recruiting
This study will be conducted as a multi-center, randomized, double-blind, placebo-controlled trial to evaluate the effect of MHS-1031 on heartburn-free days in subjects with GERD-related heartburn symptoms.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
02/29/2024
Locations: Vanderbilt University Medical Center, Nashville, Tennessee +4 locations
Conditions: Gastroesophageal Reflux
Mucosal Impedance Sleeve Gastrectomy
Recruiting
Obesity is a growing epidemic and bariatric surgery has been shown to be the most effective and efficient mean of achieving significant and sustainable weight loss in morbidly obese individuals. Studies have demonstrated that after LSG, between 5 and 30% of patients suffered from GERD, with a small subset of those patients (2.9 %) converting to another bariatric procedure (gastric bypass) because of debilitating GERD symptoms. The investigators propose this current study to examine mucosal impe... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/16/2024
Locations: MetroHealth - Main Campus Medical Center, Cleveland, Ohio
Conditions: Gastroesophageal Reflux, Bariatric Surgery Candidate
Post-sleeve Gastrectomy Gastroesophageal Reflux Disease Prediction
Recruiting
Researchers are trying to identify predictors for gastroesophageal reflux disease after sleeve gastrectomy.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/16/2024
Locations: Orlando Health, Orlando, Florida +1 locations
Conditions: Gastroesophageal Reflux, Sleeve Gastrectomy, Bariatric Surgery Complication
A Study of Breath Testing for Small Intestinal Bacterial Overgrowth
Recruiting
Researchers hope to determine how often small intestinal bacterial overgrowth occurs after taking proton pump inhibitors.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/17/2023
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Gastroesophageal Reflux, Regurgitation, Heartburn
Diagnostic Tests in Supra-Esophageal Gastroesophageal Reflux Disease (SE-GERD)
Recruiting
After defining the manometric characteristics of UES incompetence associated with documented pharyngeal reflux, we will determine the reproducibility of manometric criteria for UES incompetence in prevention of pharyngeal reflux. We hypothesize that these criteria are comprised of either a single or constellation of manometric abnormalities. After determining the ability of externally applied cricoid cartilage pressure in preventing pharyngeal reflux, we further hypothesize that this approach wi... Read More
Gender:
All
Ages:
Between 20 years and 85 years
Trial Updated:
08/08/2023
Locations: Reza Shaker, Milwaukee, Wisconsin
Conditions: Gastroesophageal Reflux
Biological Sample Repository for Gastrointestinal Disorders
Recruiting
The goal of this observational study has the purpose of collecting biological samples from obese patients undergoing evaluation for weight loss by means of medical or endoscopic therapies; and of post bariatric surgery patients presenting with short- and long-term surgical complications. The aim is to enhance the overall understanding of the mechanisms leading to obesity, weight loss, failure to lose weight, and weight regain following treatment. Additional goals are to determine the efficacy of... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/04/2023
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Obesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal Disorder, Overweight and Obesity, Overweight, Overweight or Obesity, Diabetes Type 2, Diabetes Mellitus, Diabetes Mellitus, Type 2, Hypertension, Hyperlipidemias, Sleep Apnea, GERD, Gastroesophageal Reflux, Musculoskeletal Pain Disorder, Cancer
Compassionate Use of Domperidone for Refractory Gastroparesis
Recruiting
The purpose of this program is to allow the use of domperidone in children from 12 to 21 years of age with symptoms related to motility disorders and Gastroesophageal reflux disease (GERD) who have failed all the standard treatments for their condition.
Gender:
All
Ages:
Between 12 years and 21 years
Trial Updated:
07/14/2023
Locations: Children's Mercy Hospitals and Clinics, Kansas City, Missouri
Conditions: GERD, Gastroesophageal Reflux, Gastroparesis
Barrett's Esophagus Related Neoplasia (BERN) Project
Recruiting
The use of high resolution endoscopy (HRE), narrow band imaging (NBI) and chromoendoscopy increases the detection rates of Barrett's esophagus (BE) and early neoplasia. Endoscopic mucosal resection (EMR) will improve the accuracy for detection of dysplasia/early neoplasia. Specific Aim 1 - To create a video-atlas of non-dysplastic and dysplastic/early neoplastic lesions in patients with BE. This will be used for training purposes and to assess learning curve associated with these new technologi... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/15/2023
Locations: Kansas city VA Medical center, Kansas City, Missouri
Conditions: Barrett's Esophagus, Neoplasms, Gastroesophageal Reflux