There are currently 7 active clinical trials seeking participants for Hypercholesterolemia research studies. The states with the highest number of trials for Autism participants are Florida, California, Texas and Ohio.
Onco-primary Care Networking to Support TEAM-based Care
Recruiting
The proposed ONE TEAM Study is an 18-month, cluster randomized controlled trial. This study will use a sequential multiple assignment randomized trial (SMART) design with a second randomization for the intervention group using a dynamic treatment regimen approach. The investigators propose to randomize 800 adults with newly-diagnosed selected cancers treated with curative intent (breast, prostate, colorectal, endometrial, non-small cell lung, and endometrial) and with >1 selected cardiovascular... Read More
Gender:
All
Ages:
Between 18 years and 79 years
Trial Updated:
03/15/2024
Locations: Duke University Medical Center, Durham, North Carolina
Conditions: Blood Pressure, Hypertension, Cancer, Cancer, Breast, Cancer of Prostate, Cancer Colorectal, Cancer, Endometrial, Cancer of Head and Neck, Non Small Cell Lung Cancer, CVD - Cardiovascular Disease, Diabetes Mellitus, Hypercholesterolemia, Diabetes, Cancer of Esophagus, Cancer of Liver, Cancer, Renal Cell, Cancer of Pancreas, Cancer Ovaries
A Study of MK-0616 (Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-013) CORALreef Lipids
Recruiting
The goal of this study is to evaluate the efficacy, safety, and tolerability of MK-0616 in adult participants with hypercholesterolemia. The primary hypothesis is that MK-0616 is superior to placebo on mean percent change from baseline in low-density lipoprotein cholesterol (LDL-C) at Week 24.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/15/2024
Locations: Alliance for Multispecialty Research, LLC ( Site 0093), Daphne, Alabama +166 locations
Conditions: Hypercholesterolemia, Familial Hypercholesterolemia
Causes and Natural History of Dyslipidemias
Recruiting
This study will evaluate people with dyslipidemias - disorders that affect the fat content in the blood. Fats, or lipids, such as cholesterol and triglycerides, are carried in the blood in particles called lipoproteins. These particles are involved in causing blood vessel diseases that can lead to conditions like atherosclerosis (hardening of the arteries) or heart attack. Participants will undergo accepted medical tests and procedures to evaluate their condition. Most of the test results are he... Read More
Gender:
All
Ages:
Between 2 years and 100 years
Trial Updated:
03/13/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Hypercholesterolemia, Atherosclerosis
Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies
Recruiting
The study is a placebo-controlled, double-blind, randomized, phase 3 study in participants with heterozygous familial hypercholesterolemia (HeFH) and/or atherosclerotic cardiovascular disease (ASCVD) or multiple ASCVD risk factors to evaluate the efficacy, safety and tolerability of obicetrapib 10mg and ezetimibe 10mg fixed dose combination as an adjunct to diet and maximally tolerated lipid-lowering therapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/11/2024
Locations: Jacksonville Center for Clinical Research, Jacksonville, Florida +42 locations
Conditions: Dyslipidemias, Hypercholesterolemia, Familial Hypercholesterolemia, ASCVD, High Cholesterol
Church-based Health Intervention to Eliminate Racial Inequalities in Cardiovascular Health
Recruiting
Cardiovascular disease (CVD) is the leading cause of death in the US general population. Although CVD mortality rates declined for both Black and White populations during the past two decades, they are still higher in Black adults than White adults. There are also persistent disparities in CVD risk factors with higher prevalence of obesity, hypertension, and diabetes in Black compared to White populations. In addition, CVD and risk factors are more prevalent in the residents of Louisiana compare... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
01/02/2024
Locations: Tulane University, New Orleans, Louisiana
Conditions: Cardiovascular Diseases, Hypertension, Diabetes, Hypercholesterolemia
Study of Awareness and Detection of Familial Hypercholesterolemia
Recruiting
The CASCADE-FH Registry is a national, multi-center initiative that will track the therapy, clinical outcomes, and patient-reported outcomes over time. The registry represents a collaboration between The Familial Hypercholesterolemia Foundation, the Duke Clinical Research Institute, lipid specialists, cardiologists, primary care providers, quality improvement personnel, and patients, all aiming to increase FH awareness, promote optimal disease management, and improve FH outcomes.
Gender:
All
Ages:
All
Trial Updated:
11/21/2023
Locations: Stanford Center for Inherited Cardiovascular Diseases, Palo Alto, California
Conditions: Hypercholesterolemia
A Phase 2 Clinical Study in Children With HeFH Aged 6 to 17 Treated Once Daily With Bempedoic Acid Oral Dosing
Recruiting
Multiple-dose study to measure PK, PD and safety of bempedoic acid in pediatric patients 6 to 17 years of age with HeFH.
Gender:
All
Ages:
Between 6 years and 17 years
Trial Updated:
08/08/2023
Locations: Smidt Heart Institute at Cedars-Sinai, Los Angeles, California +19 locations
Conditions: Hypercholesterolemia