There are currently 4 active clinical trials seeking participants for Hypertriglyceridemia research studies. The states with the highest number of trials for Autism participants are Florida, California, Ontario and Texas.
Effects of Replacing Energy From Solid Fats and Added Sugars (SoFAS) With Avocado
NCT04990817
Recruiting
The objective of this study is to assess the effects of replacing energy from SoFAS with energy from avocado on non-high-density lipoprotein cholesterol (non-HDL-C) and other aspects of the cardiometabolic health profile including fasting lipoprotein lipid and particle concentrations, insulin sensitivity and blood pressure in men and women with elevated triglycerides (TG).
Gender:
All
Ages:
Between 21 years and 74 years
Trial Updated:
04/01/2024
Locations: Great Lakes Clinical Trials, Chicago, Illinois +1 locations
Conditions: Elevated Triglycerides, Hypertriglyceridemia
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A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia
NCT05610280
Recruiting
The purpose of the study is to evaluate the effect of olezarsen on percent change in fasting triglyceride (TG) levels compared to placebo in participants with hypertriglyceridemia and atherosclerotic cardiovascular disease, or with severe hypertriglyceridemia.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/06/2023
Locations: Alabama Clinical Therapeutics, LLC Alabaster, Birmingham, Alabama +167 locations
Conditions: Hypertriglyceridemia, Cardiovascular Diseases, Atherosclerosis
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MN-001 in Non-alcoholic Fatty Liver Disease, Type 2 Diabetes Mellitus, and Hypertriglyceridemia
NCT05464784
Recruiting
The design of the Phase 2 clinical trial includes the following elements: Multi-center, two-arm, randomized, double-blind, placebo-controlled trial to evaluate MN-001 (tipelukast) vs. placebo in approximately 40 patients in the U.S. Patients will be randomized 1:1 to receive either 500 mg/day of MN-001 (tipelukast) or placebo for 24 weeks. The co-primary endpoints are (1) change from baseline in liver fat content measured by controlled attenuation parameter (CAP) score at Week 24, and (2) chang... Read More
Gender:
All
Ages:
Between 21 years and 75 years
Trial Updated:
09/27/2023
Locations: Jubilee Clinical Research, Inc., Las Vegas, Nevada
Conditions: Diabetes Mellitus, Type 2, Hypertriglyceridemia, Non-Alcoholic Fatty Liver Disease
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Impact of Foods on Bile Acids, Metabolites, and Inflammation
NCT05245357
Recruiting
Dietary incorporation of pulse crops may be an effective way to lower unhealthy elevations in serum bile acids. These elevations play a direct role in promoting obesity-related diseases estimated to be present in about one third of the US adult population, including non-alcoholic fatty liver disease and type 2 diabetes. The overarching hypothesis for this study is that pulse consumption increases bile acid secretion and excretion, which will decrease toxicity linked to excess accumulation of bil... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/02/2023
Locations: Nutrition Research Laboratory, Bozeman, Montana
Conditions: Inflammation, Hypertriglyceridemia, Metabolic Disease, Lipid Metabolism Disorder, Hyperlipidemias, Bile Acid Malabsorption
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