There are currently 9 active clinical trials seeking participants for Hypotension research studies. The states with the highest number of trials for Autism participants are California, Ontario, New York and Ohio.
Treatment of Orthostatic Hypotension in SCI
Recruiting
The purpose of this study is to identify the effects of non-pharmacological and pharmacological anti-hypotensive treatment interventions on orthostatic hemodynamic responses, symptoms of autonomic dysreflexia and orthostatic hypotension, and levels of fatigue and comfort in hypotensive individuals with SCI.
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
02/29/2024
Locations: Kessler Foundation, West Orange, New Jersey +1 locations
Conditions: Hypotension
Vasopressor Outcomes in Spine Surgery
Recruiting
This is a prospective, randomized control trial comparing norepinephrine versus phenylephrine for vasopressor support in patients undergoing elective spinal fusion surgery.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/11/2024
Locations: Clements University Hospital at Dallas, Dallas, Texas
Conditions: Hypotension
Restrictive Versus Liberal Rate of Extracorporeal Volume Removal Evaluation in Acute Kidney Injury
Recruiting
Critically ill patients with acute kidney injury and fluid overload who are frequently treated by fluid removal during dialysis are at an increased risk of complications and death. Both slower and faster rates of fluid removal may cause injury to the vital organs. This proposed clinical trial will examine the feasibility of restrictive compared with a liberal rate of fluid removal in order to develop effective treatments for fluid overload and to improve the health of critically ill patients.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/18/2023
Locations: Mayo Clinic, Rochester, Minnesota +1 locations
Conditions: Acute Kidney Injury, Fluid Overload, Hypotension, Dialysis; Complications, Critical Illness
Non-Invasive Cardiac Output Monitor (NICOM) for Goal-directed Fluid Resuscitation for Inpatients With Hypotension and/or Septic Shock
Recruiting
The Non-Invasive Cardiac Output Monitor (NICOM) is a non-invasive monitor capable of measuring cardiac output (CO) and cardiac index (CI), and stroke volume (SV) and stroke volume index (SVI) based on heart rate. Conceptually NICOM is a technology that utilizes a dynamic response characteristic in assessing the need for fluid administration, whereby SVI is measured before and after a fluid challenge with more fluid given only if SVI increases significantly with administered fluid. Dynamic respon... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/31/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Sepsis, Hypotension, Septic Shock
Study to Determine the Pharmacokinetics and Pharmacodynamic Effects of Phenylephrine on BP Via IV
Recruiting
The primary objective of this study is to evaluate the dose effect of Phenylephrine Hydrochloride Injection on the treatment of clinically relevant decreased blood pressure in the pediatric population, ≥12 to 16 year old patients undergoing general and neuraxial anesthesia. The secondary objectives are to describe changes in blood pressure and heart rate, time to onset and to maximal response, and the duration of response; to assess the safety of the product in this population; and to character... Read More
Gender:
All
Ages:
Between 12 years and 16 years
Trial Updated:
07/11/2023
Locations: Alfred I. DuPont Hospital for Children, Wilmington, Delaware +9 locations
Conditions: Hypotension
Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI)
Recruiting
The goal of this clinical trial is to evaluate the effect of transcutaneous spinal cord stimulation on blood pressure in individuals with an acute spinal cord injury (within 30 days of injury). Blood pressure instability, specifically orthostatic hypotension (a drop in blood pressure when moving lying flat on your back to an upright position), appears early after the injury and often significantly interferes with participation in the critical rehabilitation time period. The main questions it ai... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/08/2023
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: Spinal Cord Injuries, Spinal Cord Diseases, Trauma, Nervous System, Nervous System Diseases, Central Nervous System Diseases, Hypotension, Orthostatic Hypotension, Cardiovascular Diseases, Acute Spinal Cord Injury, Blood Pressure
The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI)
Recruiting
This project will investigate the effect of spinal cord transcutaneous stimulation on blood pressure in individuals with a chronic spinal cord injury who experience blood pressure instability, specifically, orthostatic hypotension (a drop in blood pressure when moving from lying flat on your back to an upright position). The main questions it aims to answer are: What are the various spinal sites and stimulation parameters that normalize and stabilize blood pressure during an orthostatic provoc... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/08/2023
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: Spinal Cord Injuries, Hypotension, Orthostatic Hypotension, Spinal Cord Diseases, Cardiovascular Diseases, Trauma, Nervous System, Central Nervous System Diseases, Nervous System Diseases, Blood Pressure
TSCS for Acute SCI
Recruiting
This project will focus on a novel approach to stabilizing blood pressure (BP) during inpatient rehabilitation after acute SCI. After SCI, people have unstable blood pressure, ranging from too low (orthostatic hypotension) to too high (autonomic dysreflexia). Unstable BP often interferes with performing effective physical rehabilitation after SCI. A critical need exists for the identification of safe, practical and effective treatment options that stabilize BP after traumatic SCI. Transcutaneous... Read More
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
01/05/2023
Locations: Mount Sinai Spinal Cord Injury Model System, New York, New York
Conditions: Acute Spinal Cord Injury, Blood Pressure, Hypotension
Acupuncture for the Treatment of Medication-Dependent Hypotension in Heart Failure
Recruiting
Acupuncture is believed to increase blood pressure in people who struggle with low blood pressure. This is a common problem facing people with heart failure, and sometimes these people need to take medications to artificially increase their blood pressure. This study is designed to determine if using acupuncture in people with heart failure can improve their blood pressure enough to not require medications to artificially increase blood pressure.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/02/2021
Locations: Scripps La Jolla Medical Center, La Jolla, California +1 locations
Conditions: Congestive Heart Failure, Hypotension