There are currently 37 active clinical trials seeking participants for Ischemic Stroke research studies. The states with the highest number of trials for Autism participants are California, Florida, New York and Ohio.
Biomarkers of Acute Stroke in Clinic
NCT03897478
Recruiting
The proposed study will investigate the clinical use of the ISCDX test that may differentiate between diverse stroke etiologies as listed below: Aim 1: Differentiate between cardioembolic and large artery atherosclerotic ischemic strokes, when hemorrhagic stroke is ruled out, as defined by TOAST classification of subtypes of acute ischemic stroke. Aim 2: In cases of ischemic strokes of unknown or "cryptogenic" etiology, determine the ability of biomarker blood tests to predict etiology between... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
09/26/2023
Locations: Ohio Health Riveside Methodist Hospital, Columbus, Ohio
Conditions: Ischemic Stroke, Ischemia, Atrial Fibrillation, Transient Ischemic Attack, Transient Cerebrovascular Events, Thrombotic Stroke, Stroke, Stroke, Acute, Stroke, Ischemic, Stroke, Complication, Stroke of Basilar Artery, Atherosclerosis, Atheroma, Cardioembolic Stroke, Cardiomyopathies, Cardiovascular Stroke, Thromboembolism
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K01 Impacts of Lingual Endurance Exercise
NCT06072924
Recruiting
Swallowing impairments (dysphagia) frequently occur after stroke and have devastating consequences on overall health and quality of life, and long-term deficits in swallow function also increase risk of morbidity (e.g. depression) and mortality (i.e. aspiration pneumonia). As such, rehabilitation of swallow function to improve safety and efficiency of swallowing is essential in this population. This study aims to: 1) Provide preliminary data to evaluate the effect of a novel lingual endurance ex... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/02/2023
Locations: University of Cincinnati, Cincinnati, Ohio
Conditions: Dysphagia, Dysphagia, Oropharyngeal, Ischemic Stroke
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Distal Ischemic Stroke Treatment With Adjustable Low-profile Stentriever
NCT05152524
Recruiting
The objective of the DISTALS Study is to evaluate the safety and effectiveness of the Tigertriever 13 Revascularization Device in restoring blood flow in the neurovasculature by removing thrombus in patients presenting within 24 hours of onset with an ischemic stroke with disabling neurological deficits due to a primary distal vessel occlusion (DVO), as compared to medical management.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
04/18/2024
Locations: Honor Health, Phoenix, Arizona +22 locations
Conditions: Ischemic Stroke, Neovascularization
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Combined Thrombectomy for Distal MediUm Vessel Occlusion StroKe
NCT05983757
Recruiting
A phase III, randomized, multi-center, investigational, open label clinical trial that will examine whether treatment with endovascular thrombectomy is superior to standard medical therapy alone in patients who suffer a Distal Medium Vessel Occlusion Ischemic Stroke within 12 hours from time last seen well
Gender:
All
Ages:
18 years and above
Trial Updated:
04/16/2024
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Ischemic Stroke
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Procedural Motor Memory in Long COVID-19
NCT05746624
Recruiting
Background: Most people who get COVID-19 seem to recover with no long-term effects. However, some people who recover from acute COVID-19 infections report lingering symptoms. This is called long COVID. Many people with long COVID report symptoms related to the nervous system; these can include problems with fatigue, speech, and memory. Objective: To test motor memory in people with long COVID, compared to healthy volunteers. Eligibility: People aged 18 to 90 years who are also enrolled in s... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
04/03/2024
Locations: National Institute of Neurological Disorders and Stroke (NINDS), Bethesda, Maryland
Conditions: Infectious Metabolic Encephalopathy, Ischemic Stroke, Seizure, Viral Encephalitis, Small and Large Vessel
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NOninVasive Intracranial prEssure From Transcranial doppLer Ultrasound Development of a Comprehensive Database of Multimodality Monitoring Signals for Brain-Injured Patients
NCT04548596
Recruiting
This is an observational study in neurocritical care units at University of California San Francisco Medical Center (UCSFMC), Zuckerberg San Francisco General Hospital (ZSFGH), and Duke University Medical Center. In this study, the investigators will primarily use the monitor mode of the Transcranial Doppler (TCD, non-invasive FDA approved device) to record cerebral blood flow velocity (CBFV) signals from the Middle Cerebral Artery and Internal Carotid Artery. TCD data and intracranial pressure... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/01/2024
Locations: University of California San Francisco, San Francisco, California +2 locations
Conditions: Traumatic Brain Injury, Subarachnoid Hemorrhage, Intracerebral Hemorrhage, Liver Failure, Ischemic Stroke
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Sleep for Stroke Management and Recovery Trial
NCT03812653
Recruiting
The purpose of this study is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke or high risk TIA (1) reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6 months after the event, and (2) improves stroke outcomes at 3 months in patients who experienced an ischemic stroke.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/29/2024
Locations: University of Alabama Hospital, Birmingham, Alabama +109 locations
Conditions: Ischemic Stroke, Sleep Apnea, Sleep Apnea, Obstructive, TIA, Stroke, CPAP, Telemedicine, Home Sleep Apnea Test, Randomized Clinical Trial, Multicenter Trial
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Strategy for Improving Stroke Treatment Response
NCT05948566
Recruiting
SISTER is a Phase-II, prospective, randomized, placebo-controlled, blinded, dose finding trial that aims to determine the safety and preliminary efficacy of TS23, a monoclonal antibody against the alpha-2 antiplasmin (a2-AP), in acute ischemic stroke.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/21/2024
Locations: UCSD Health La Jolla, La Jolla, California +14 locations
Conditions: Ischemic Stroke
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Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial
NCT05478304
Recruiting
This trial is a prospective, randomized, multicenter, multinational, blinded, superiority trial. The objective of this trial is to evaluate the effectiveness of left atrial appendage exclusion (LAAE) for the prevention of ischemic stroke or systemic arterial embolism in subjects undergoing cardiac surgery who have risk factors for atrial fibrillation and ischemic stroke.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/07/2024
Locations: Heart Center Research / Huntsville Hospital, Huntsville, Alabama +67 locations
Conditions: Ischemic Stroke, Systemic Embolism
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Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)
NCT05065216
Recruiting
This is a Phase 2/3 study evaluating the safety and efficacy of DM199 in treating participants presenting within 24 hours of Acute Ischemic Stroke (AIS) onset for whom fibrinolytics and/or a catheter-based procedure, mechanical thrombectomy (MT), are not medically appropriate or available due to constraints of clot location, comorbidity risks, and/or time from estimated onset of stroke. The double-blinded study will be randomized, placebo controlled at up to approximately 100 sites.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: Washington Regional Medical Center, Fayetteville, Arkansas +11 locations
Conditions: Acute Stroke, Ischemic Stroke, Stroke
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A Safety and Tolerability Study of Neural Stem Cells (NR1) in Subjects With Chronic Ischemic Subcortical Stroke (ISS)
NCT04631406
Recruiting
Evaluation of the safety and tolerability of escalating doses of NR1 administered intracerebrally at a single time-point post-injury to subjects with chronic ISS with or without cortical stroke.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
02/20/2024
Locations: Stanford Health Center, Stanford, California
Conditions: Ischemic Stroke
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CTSN Embolic Protection Trial
NCT06027788
Recruiting
This is a prospective, multi-center, randomized effectiveness trial of the CardioGard Embolic Protection Cannula in high-risk valve surgery patients.
Gender:
All
Ages:
60 years and above
Trial Updated:
02/14/2024
Locations: CHI St. Vincent Heart Institute, North Little Rock, Arkansas +18 locations
Conditions: Delirium, Ischemic Stroke, Acute Kidney Injury, Heart Valve Disease, Coronary Artery Disease
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