There are currently 24 active clinical trials seeking participants for Malignant Neoplasm research studies. The states with the highest number of trials for Malignant Neoplasm participants are Michigan, Illinois, Nevada and California.
Germ-Line Mutations in Blood and Saliva Samples From Patients With Cancer
NCT02280161
Recruiting
This research trial studies germ-line mutations in blood and saliva samples from patients with cancer. Studying samples of blood and saliva from patients with cancer in the laboratory may help doctors learn more about how inherited genetic mutations can affect cancer predisposition (an inherited increase in the risk of developing cancer), their impact on treatment response, and their role in cancer development.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/04/2024
Locations: Jonsson Comprehensive Cancer Center, Los Angeles, California
Conditions: Malignant Neoplasm
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Molecular Genetics Studies of Cancer Patients and Their Relatives
NCT04185935
Recruiting
This trial studies the genetic and behavioral factors that may contribute to the development of specific cancers and how these factors may affect the outcome of the disease in patients with a history of cancer and their relatives.
Gender:
ALL
Ages:
All
Trial Updated:
10/01/2024
Locations: Valleywise Comprehensive Health Center - Phoenix, Phoenix, Arizona +41 locations
Conditions: Malignant Neoplasm
Register for Updates
Virtual Reality in Reducing Pain and Anxiety in Cancer Participants Undergoing Painful Procedures
NCT03568292
Recruiting
This trial studies how well virtual reality (VR) works in reducing pain and anxiety in cancer participants undergoing bone marrow biopsy or lumbar puncture. Virtual reality may impact pain and anxiety during and after the procedure.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
08/27/2024
Locations: USC / Norris Comprehensive Cancer Center, Los Angeles, California
Conditions: Malignant Neoplasm
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Intraoperative Tumor Margin Identification With ICG Dye Imaging
NCT04752137
Recruiting
In this research study we want to learn more about the use of indocyanine green (ICG) during bone or soft tissue mass resections. Indocyanine green (ICG) is a type of dye that is used in medical diagnostics. We want to determine if ICG-guided tumor resection is more effective in obtaining negative margins. Lastly, we want to assess traditional oncologic outcomes of local recurrence, time to metastatic disease, and overall and disease specific survival.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/05/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Benign Neoplasm, Malignant Neoplasm
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Novel Outreach Methods to Increase Enrollment to Early Phase Clinical Trials
NCT05886764
Recruiting
This trial will study different outreach methods to assess impact on enrollment of underrepresented minorities (specifically African Americans) to early phase cancer clinical treatment trials. Both patients and providers (those seeing enrolled patients) will be enrolled and receive the study interventions or no intervention (control arm).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/28/2024
Locations: University of Chicago Medicine Comprehensive Cancer Center, Chicago, Illinois
Conditions: Cancer, Malignancy, Malignant Neoplasm
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Collection of Immunology Specimens From Patients With Cancer or Blood Disorders, and Healthy Volunteers
NCT03207854
Recruiting
This research trial collects and stores blood, tissue, and bone marrow specimens from patients with cancer or blood disorders, and healthy volunteers to study the immune system in a variety of different types of experiments, as well as associated clinical data as appropriate, focused on understanding mechanisms of immunotherapy.
Gender:
All
Ages:
19 years and above
Trial Updated:
05/22/2024
Locations: USC / Norris Comprehensive Cancer Center, Los Angeles, California
Conditions: Healthy Subject, Hematologic and Lymphocytic Disorder, Hematopoietic and Lymphoid Cell Neoplasm, Immune System Disorder, Malignant Neoplasm
Register for Updates
A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant
NCT04453072
Recruiting
This early phase I trial studies how well a behavioral weight loss intervention consisting of a smartphone application and coaching works for the promotion of weight loss in adolescents and young adults after a stem cell transplant. This study may help researchers learn more about how adolescents and young adults can lose weight and develop healthy eating habits.
Gender:
All
Ages:
Between 13 years and 30 years
Trial Updated:
04/11/2024
Locations: UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, California
Conditions: Obesity, Malignant Neoplasm
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Norris ORIEN Total Cancer Care
NCT02970045
Recruiting
This research trial collects biological samples and clinical information to create a repository of data from patients with cancer or a predisposition for cancer. Combining genetic information from biological samples and clinical data may lead to more knowledge about why certain cancers respond to treatment and help create more personalized medicine.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/14/2024
Locations: USC / Norris Comprehensive Cancer Center, Los Angeles, California
Conditions: Cancer Risk, Malignant Neoplasm
Register for Updates
Engagement of American Indians of Southwestern Tribal Nations in Cancer Genome Sequencing
NCT06207864
Recruiting
This clinical trial studies engagement strategies for recruiting American Indians (AI) of Southwestern Tribal Nations for cancer genome sequencing. American Indians in the Southwest have higher rates of some types of cancer, such as cancers that arise in the liver, kidney, breast, and colon. American Indians with cancer may also live for less time than people from other population groups who have been treated for the same cancer. Damage to the cells of the body, acquired as people live, grow old... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/30/2024
Locations: University of New Mexico Comprehensive Cancer Center, Albuquerque, New Mexico
Conditions: Malignant Neoplasm
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A Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With Anticancer Agents
NCT05094804
Recruiting
This is an open-label, multicenter, first-in-human dose-escalation and expansion Phase 1-2 study designed to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary anti-tumor activity of OR2805 administered as a monotherapy and in combination with anti-cancer agents in subjects with advanced solid tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/31/2023
Locations: HonorHealth Research Institute, Scottsdale, Arizona +2 locations
Conditions: Cancer, Tumor, Solid, Malignant Neoplasm, Metastatic Cancer, Advanced Solid Tumor, Non Small Cell Lung Cancer, Melanoma, Head and Neck Squamous Cell Carcinoma, Leiomyosarcoma, Liposarcoma
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Patient-Derived Xenografts to Reduce Cancer Health Disparities
NCT04410302
Recruiting
This trial establishes patient-derived cancer xenografts in addressing cancer health and treatment disparities that disproportionately affect racial/ethnic minorities. Understanding the genetic and response differences among racial/ethnic minorities may help researchers enhance the precision of therapeutic treatments.
Gender:
All
Ages:
Between 21 years and 100 years
Trial Updated:
10/12/2023
Locations: UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California +1 locations
Conditions: Bladder Carcinoma, Gastric Carcinoma, Liver and Intrahepatic Bile Duct Carcinoma, Lung Carcinoma, Malignant Neoplasm
Register for Updates
Targeted Genomic Analysis of Blood and Tissue Samples From Patients With Cancer
NCT02688517
Recruiting
This research trial studies the use of targeted genomic analysis of blood and tissue samples from patients with cancer. Genomic sequencing is a laboratory method that is used to determine the entire genetic makeup of a specific organism or cell type. Genomic sequencing can be used to find changes in areas of the genome that may be important in the development of cancer. It may also help doctors improve ways to diagnose and treat patients with rare cancers with poor prognosis or lack of effective... Read More
Gender:
All
Ages:
1 year and above
Trial Updated:
08/03/2023
Locations: Ocean Medical Center, Brick, New Jersey +10 locations
Conditions: Malignant Neoplasm
Register for Updates