There are currently 21 active clinical trials seeking participants for Neuropathic Pain research studies. The states with the highest number of trials for Autism participants are Florida, California, Texas and North Carolina.
Vitamin D Supplementation on Reported Rates of Taxane-Induced Neuropathy
Recruiting
This is a two-arm randomized clinical trial in which 80 participants with Vitamin D deficiency and scheduled to begin taxane-based chemotherapy will be randomized to either: 1) prescribed vitamin D replacement or 2) standard of care.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/28/2024
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Neuropathic Pain
Insula Neuromodulation for Chronic Neuropathic Pain
Recruiting
This study will comprehensively investigate the insula as a brain target for neuromodulation to treat chronic neuropathic pain.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/03/2023
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Neuropathic Pain, Chronic Pain
Virtual Walking Therapy for Neuropathic Pain Following Incomplete Spinal Cord Injury
Recruiting
The purpose of this study is to determine if playing a virtual reality walking game can help improve neuropathic pain in adults with incomplete spinal cord injury.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/19/2024
Locations: Texas A&M University, College Station, Texas
Conditions: Spinal Cord Injuries, Neuropathic Pain
The Use of Venlafaxine in Reducing Pain in Primary Total Knee Replacement
Recruiting
Patients experience pain after their knee replacement surgery - and some may continue to experience persistent pain long after their knee replacement surgery. Traditional pain management strategies reply on pain medication such as opioids for pain control. However, these drugs do not work well for pain associated with movement or the the nerve pain (tingling, electrical sensations) after surgery. In addition, opioids are associated with significant side effects such as nausea, vomiting, respirat... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
02/27/2024
Locations: University of California San Francisco, San Francisco, California
Conditions: Acute Pain, Chronic Pain, Knee Pain Chronic, Neuropathic Pain
Brivaracetam to Reduce Neuropathic Pain in Chronic SCI: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Recruiting
Spinal cord injury (SCI) is associated with severe neuropathic pain that is often refractory to pharmacological intervention. Preliminary data suggest brivaracetam is a mechanism-based pharmacological intervention for neuropathic pain in SCI. Based on this and other reports in the literature, SCI-related neuropathic pain is hypothesized to occur largely because of upregulation of synaptic vesicle protein 2A (SV2A) within the substantia gelatinosa of the injured spinal cord. Furthermore, compared... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/16/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Spinal Cord Injuries, Neuropathic Pain
Addressing Disparities in Neuromodulation for Rehabilitation: A Mixed Methods Approach to Optimize Access for Underrepresented Racial Minorities
Recruiting
The purpose of this study is to: Development of culturally sensitive videos for enhance informed consent with neurostimulation and determination of factors that influence minority interest in participating in neurostimulation research. Examination of the influence that video enhanced informed consent has on expectations with transcutaneous auricular vagus nerve stimulation (taVNS) and on treatment intended effects.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/14/2024
Locations: University of Miami, Miami, Florida
Conditions: Neuropathic Pain
Real-World Efficacy of Evoke® Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy in Chronic Pain Patients (ULTRA).
Recruiting
This observational, prospective data collection is designed to evaluate the efficacy of CL-SCS therapy in real-world patients suffering from chronic pain.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/06/2024
Locations: The Spine and Nerve Center of Saint Francis Hospital, Charleston, West Virginia
Conditions: Pain, Chronic Pain, Neuropathic Pain
Prospective Evaluation of Intrathecal Targeted Drug Delivery for Cancer Associated Pain
Recruiting
This Registry study will prospectively evaluate the differences in treatment outcomes in terms of pain intensity, pain interference, concomitant medication use, health-related quality of life, opioid adverse effects, and healthcare utilization between targeted drug delivery and conservative medication management only groups.
Gender:
All
Ages:
21 years and above
Trial Updated:
01/15/2024
Locations: Advocate Aurora Health, Oshkosh, Wisconsin
Conditions: Cancer Pain, Chronic Pain, Cancer Associated Pain, Neuropathic Pain
Intraoral Administration of Botox in Patients With Dentoalveolar Neuropathic Pain
Recruiting
Onabotulinum toxin type A (BoNT-A) is a potent neurotoxin that has been reported to have an effect on afferent (sensory) neurons independent of its action on muscle tone and secretory glands at the periphery.In human studies, the use of BoNT-A has proven to reduce the severity and intensity of attacks in chronic tension type headaches and chronic neck pain. The PREEMPT study concluded that BoNT-A could be used as a preventive therapy in chronic migraine patients and FDA approval was obtained. Ac... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
12/22/2023
Locations: Orofacial Pain Center, Lexington, Kentucky
Conditions: Neuropathic Pain
Intraoperative Neuromonitoring Recording With a Novel SCS Paddle: Phase II
Recruiting
The purpose of this study is to demonstrate safety and efficacy of a new spinal cord stimulation paddle electrode which is able to target the dorsal horns, dorsal nerve roots, and dorsal columns. The research electrode ("Study Electrode") is designed to answer basic physiological clinical research questions. It may inform future device therapy development, but the Study Electrode is not a product that will be marketed or sold. The Investigators believe the protocol is a Non-Significant Risk stud... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
12/07/2023
Locations: Albany Medical College, Albany, New York
Conditions: Chronic Pain, Neuropathic Pain, Failed Back Surgery Syndrome, Complex Regional Pain Syndromes
Utility of Multisensory Body-Representation in Spinal Cord Injury (SCI) With Pain
Recruiting
The purpose of this study is to investigate the effectiveness of bodily illusions combined with transcranial direct current stimulation (tDCS) on neuropathic pain symptoms and sensory functions in participants with spinal cord injury (SCI) and neuropathic pain.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
10/31/2023
Locations: University of Miami, Miami, Florida
Conditions: Spinal Cord Injuries, Neuropathic Pain
Sensory Testing of Multiple Forms of Spinal Cord Stimulation for Pain
Recruiting
Doctors sometimes treat chronic pain with devices that send mild electrical currents into the spinal cord. This type of treatment is referred to as neurostimulation. A common form of neurostimulation therapy is spinal cord stimulation (SCS). In this study, researchers want to learn more about how SCS affects pain processing and relieves pain. The researchers will examine multiple forms of SCS in chronic pain patients who are receiving SCS from their own doctors as part of their standard of care.... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/06/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Chronic Pain, Failed Back Surgery Syndrome, Complex Regional Pain Syndromes, Neuropathic Pain