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Nicotine Dependence Clinical Trials
A listing of 24 Nicotine Dependence clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 24
There are currently 24 active clinical trials seeking participants for Nicotine Dependence research studies. The states with the highest number of trials for Nicotine Dependence participants are California, North Carolina, Connecticut and Pennsylvania.
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Healthy Volunteer Trials
Recruiting
Healthy trials near you are looking for participants to help push medical research forward. Click through to learn more!
Conditions:
Healthy
Featured Trial
Chronic Cough Clinical Study
Recruiting
We are evaluating an investigational treatment to see if it may help people dealing with chronic cough.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required.
Conditions:
Cough
Chronic Cough
Asthma
Allergic Asthma
Sinusitis
Featured Trial
High blood pressure (Hypertension) Trials
Recruiting
High blood pressure (Hypertension) trials near you are looking for participants to help push medical research forward. Click through to learn more!
Conditions:
High blood pressure (Hypertension)
Research and Innovation to Stop E-cigarette/Vaping in Young Adults
Recruiting
The aim of this study is to test intervention components to help young adults quit vaping. A 2x2 factorial design will be used where all participants receive quitline-delivered behavioral phone counseling, and components to be tested are a digital intervention (with text and online cessation support) and nicotine replacement therapy (NRT).
The research questions and hypotheses for this study are:
Which components and combinations of intervention yield the greatest success rates for exclusive v... Read More
Gender:
All
Ages:
Between 18 years and 24 years
Trial Updated:
10/03/2022
Locations: The Ohio State University, Columbus, Ohio
Conditions: Nicotine Dependence, E-Cig Use
Advanced Functional and Structural MRI Techniques for Neuropharmacological Imaging
Recruiting
Background:
- Functional and structural magnetic resonance imaging (MRI) techniques have allowed researchers to map and study how the brain works when at rest and when engaged in specific tasks. MRI scans have provided more information about how drugs affect the brain, and about how drug addiction changes the brain and influences behavior, mood, and thinking processes. To better understand the underlying mechanism of drug addiction and to develop strategies for more effective treatment, researc... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
06/19/2024
Locations: Georgetown University, Washington, District of Columbia +1 locations
Conditions: Drug Abuse, Nicotine Dependence
Cognitive Task Development and Implementation for Functional MRI Studies
Recruiting
Background:
Drugs of abuse have effects on mood, behavior, thinking, and decision making that may encourage people to continue using them and make it difficult for them to stop. Researchers who study these effects are interested in developing new tests to evaluate how drugs and drug use affect different areas of the brain.
Magnetic resonance imaging (MRI) scans allow researchers to study brain activity and changes to brain function. When specific psychological tests are performed during functio... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
06/19/2024
Locations: National Institute on Drug Abuse, Biomedical Research Center (BRC), Baltimore, Maryland
Conditions: Drug Abuse, Nicotine Dependence
Understanding How Cigarette Direct Mail Marketing Influences Smoking Behaviors Among High and Low Socioeconomic Status Young Adult Smokers
Recruiting
Background:
Smoking is a major public health problem in the U.S. Almost a half a million Americans die from it in a year. One thing that contributes to why people smoke is the marketing of cigarettes. Cigarette direct mail marketing usually targets young smokers of lower socioeconomic status. Researchers want to find out more about how this kind of marketing influences smoking behavior in young people from different socioeconomic levels.
Objectives:
To study the effects of cigarette direct ma... Read More
Gender:
All
Ages:
Between 18 years and 29 years
Trial Updated:
06/12/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Nicotine Dependence
Pharmacokinetics, Subjective Effects, and Abuse Liability of Nicotine Salt-Based Vaping Products With Tobacco or Unflavored E-liquids, SALTVAPE Study
Recruiting
This trial studies activity of time (pharmacokinetics), subjective effects, and abuse liability of nicotine salt-based vaping products with tobacco or e-liquids. This study aims to determine and compare the levels of nicotine delivered to the bloodstream from nicotine salt and free-base nicotine e-liquid solutions.
Gender:
All
Ages:
Between 21 years and 55 years
Trial Updated:
06/11/2024
Locations: Roswell Park Cancer Institute, Buffalo, New York
Conditions: Nicotine Dependence
Multimodal Neuroimaging Genetic Biomarkers of Nicotine AddictionSeverity
Recruiting
Background:
- Smoking is a difficult habit to quit, and some people find it more difficult to quit than others do. Nicotine is the substance in cigarettes that makes smoking so addictive. Nicotine changes some patterns of brain activity, and smokers have differences in brain activity when compared to non-smokers. Some genes make it more likely that a person will become addicted to smoking. Researchers want to study how nicotine interacts with genes and brain activity. This may help develop bett... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
06/06/2024
Locations: National Institute on Drug Abuse, Baltimore, Maryland
Conditions: Nicotine Dependence
Effects of E-cigs vs Pouches on Cigarette Smoking and Addiction
Recruiting
The study will recruit an anticipated 256 adults who currently smoke cigarettes and report a willingness to try switching to alternative, non-combustible products. Participants will be randomized to receive either e-cigarettes or nicotine pouches for a duration of 4 weeks and to 1 of 4 possible regulatory scenarios within products where flavor availability is either menthol and tobacco/unflavored available or tobacco/unflavored only available, and nicotine concentration is either higher (5% e-ci... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
05/30/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Smoking, Smoking Behaviors, Nicotine Dependence
Young Adult Tobacco/Nicotine and Cannabis Co-use
Recruiting
The goal of this project is to better understand the relationship between tobacco/nicotine and cannabis using behavioral economics during a tobacco/nicotine quit attempt. All participants will receive tobacco/nicotine cessation treatment (smoking and/or vaping treatment) for 12 weeks. To qualify, participants must be between the ages of 18-25 and use tobacco products (smoke cigarettes and/or vape nicotine) and use cannabis (in any form). Participants do not need to be interested in quitting cann... Read More
Gender:
All
Ages:
Between 18 years and 25 years
Trial Updated:
05/15/2024
Locations: Medical University of South Carolina - Charleston, Charleston, South Carolina
Conditions: Tobacco Use Disorder, Nicotine Dependence
Overcoming Nicotine Dependence to Enable Quitting
Recruiting
Tobacco use disorder is a chronic, relapsing health condition that necessitates a chronic care approach. However, traditional smoking cessation treatment programs allocate nearly all their resources only to those smokers who are willing to set a quit date. This is problematic because few smokers are ready to set a quit date at any given time, and a smoker's stated intention to quit can change rapidly.
One novel potential treatment strategy is to foster practice quitting (PQ), defined as attempt... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/09/2024
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Tobacco Use, Smoking Cessation, Smoking Behaviors, Nicotine Dependence, Nicotine Withdrawal
Racial Differences in Circadian and Sleep Mechanisms for Nicotine Dependence, Craving, and Withdrawal
Recruiting
The number one preventable cause of death in the world is tobacco use. Cigarette smoking in particular, costs an estimated $300 billion due to expenses related to medical care and lost productivity. Despite similar smoking prevalence rates, blacks suffer disproportionately from smoking-related harms compared to whites.Sleep disparities such as shortened sleep duration, shorter circadian periodicity, earlier chronotype, and increased variability of sleep timing have been reported more frequently... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: University of Alabama, Birmingham, Birmingham, Alabama
Conditions: Smoking, Sleep Disturbance, Nicotine Dependence
Network-Targeted Neuromodulation for Nicotine Dependence in Schizophrenia
Recruiting
The goal of this clinical trial is to compare two active types of transcranial magnetic stimulation in two nicotine-using populations: nicotine-using people with psychosis and nicotine-using people without a diagnosis of a psychotic disorder. The main questions it aims to answer are:
Can rTMS change functional connectivity in brain circuits associated with nicotine use?
Are those rTMS-induced changes in functional connectivity related to craving?
Participants will complete tasks assessing thei... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/24/2024
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Schizophrenia, Nicotine Dependence
THC Crossover Study
Recruiting
This is a randomized, crossover study enrolling experienced dual cannabis-tobacco smokers (N=18) to describe the differences in THC and toxicant exposure, examining pharmacokinetic, subjective, and cardiovascular effects from smoking and vaping dry herb cannabis. This study will also examine the differences in toxicant exposure and cardiovascular disease risk between smoking cannabis and smoking tobacco cigarettes.
Gender:
All
Ages:
21 years and above
Trial Updated:
04/22/2024
Locations: Zuckerberg San Francisco General Hospital, San Francisco, California +1 locations
Conditions: THC, Cannabis, Cannabis Smoking, Cannabis Use, Unspecified, Cigarette Smoking, Tobacco Use, Nicotine Dependence, Nicotine Withdrawal, Cardiovascular Risk Factor
1 - 12 of 24