There are currently 15 active clinical trials seeking participants for Pelvic Organ Prolapse research studies. The states with the highest number of trials for Autism participants are Ohio, Pennsylvania, California and New Jersey.
Pessary Experience Study
Recruiting
Pessaries are silicone devices inserted into the vagina for treatment of pelvic organ prolapse or stress urinary incontinence. They are adequate treatment options for patients who are poor surgical candidates, those who decline surgical intervention, or as a temporizing measure in those ultimately planning surgery. Most studies suggest that about 75% of patients are able to be successfully fit with a pessary, but about 50% discontinue pessary use within 12 months of initiation. The purpose of th... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
08/26/2023
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Pelvic Organ Prolapse, Stress Urinary Incontinence
Ethicon Pelvic Mesh Post Market Clinical Follow-up Registry
Recruiting
The objective of this post market, clinical registry is to evaluate the performance of the products of the TVT family of products or vaginal vault or uterine prolapse repair (with laparotomic or laparoscopic approach including robotic assisted) using either Gynemesh PS Mesh or Artisyn Mesh in women undergoing surgery for SUI and POP.
Gender:
Female
Ages:
21 years and above
Trial Updated:
03/25/2024
Locations: Yale University, New Haven, Connecticut +10 locations
Conditions: Stress Urinary Incontinence, Pelvic Organ Prolapse
GYNEMESH PS Mesh Post Marketing Clinical Follow-Up Study
Recruiting
The objective of this retrospective and prospective, single-arm, observational, multicenter, post-market study is to evaluate outcomes in women who underwent surgery for vaginal or uterine prolapse with a GYNEMESH PS Mesh.
Gender:
Female
Ages:
21 years and above
Trial Updated:
03/25/2024
Locations: Institute for Female Pelvic Medicine, North Wales, Pennsylvania +2 locations
Conditions: Pelvic Organ Prolapse
EVeRLAST 2-Year Follow-Up
Recruiting
This is a 2-year follow-up study from EVeRLAST which objective was to determine whether expedited resumption of postoperative activity levels is non-inferior to standard activity restrictions with respect to short-term anatomic prolapse outcomes. The preliminary data from the original study suggest expedited instructions are non-inferior. We hypothesize this effect continues at the 2-year postoperative mark and patients continue to have non-inferior outcomes after prolapse surgery when compared... Read More
Gender:
Female
Ages:
All
Trial Updated:
02/27/2024
Locations: Duke University Medical Center, Durham, North Carolina
Conditions: Pelvic Organ Prolapse
Urinary Catheter Self-Discontinuation After Urogynecology Surgery
Recruiting
The goal of this randomized clinical trial is to determine if removal of transurethral urinary catheters by patients at home is as safe as catheter removal in the office following urogynecologic surgery. Participants will be randomized to either standard catheter removal in the office or catheter self-removal at home.
Gender:
Female
Ages:
18 years and above
Trial Updated:
01/08/2024
Locations: University of Texas of Austin - Dell Seton Medical Center, Austin, Texas +3 locations
Conditions: Urinary Retention, Pelvic Organ Prolapse, Stress Urinary Incontinence, Catheter Related Complication
Intraperitoneal Bupivacaine for Pelvic Organ Prolapse
Recruiting
The purpose of this study is to evaluate the effects of 30 mL intraperitoneal Bupivacaine without epinephrine 0.25% on postoperative pain control in patients undergoing pelvic organ prolapse repair. The investigators hypothesize that use of intraperitoneal Bupivacaine will decrease postoperative pain scores and opiate consumption in the postoperative period, following pelvic organ prolapse repair.
Gender:
Female
Ages:
Between 18 years and 90 years
Trial Updated:
11/06/2023
Locations: IU north, Carmel, Indiana
Conditions: Pelvic Organ Prolapse
EASE: The Materna Prep Pivotal Study
Recruiting
This study is designed to evaluate the safety and effectiveness of the Materna Prep Device in reducing pelvic muscle injuries during vaginal delivery. Subjects are randomized to Materna Prep Device or Standard of Care without use of the Materna Prep Device Intervention with the Materna Prep Device is expected to be a one-time use of approximately 30-90 minutes during the 1st stage of labor. Subject participation in the study is targeted to be 12 months from the time of the use of the device d... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
10/17/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama +14 locations
Conditions: Vaginal Delivery, Pelvic Organ Prolapse
Retroperitoneal Tunneling Versus Dissection Technique During Sacrocolpopexy
Recruiting
The purpose of this study is to compare operative time, patient reported outcomes, surgical complications, and surgical outcomes between the tunneling versus dissection technique during robotic assisted sacrocolpopexy (RA SCP).
Gender:
Female
Ages:
18 years and above
Trial Updated:
08/17/2023
Locations: University of Texas Medical Branch Galveston, Galveston, Texas
Conditions: Pelvic Organ Prolapse
Absorbable Suture vs Permanent Suture in Sacrospinous Ligament Suspension
Recruiting
Sacrospinous ligament suspension (SSLS) was first described in 1958. It is commonly performed for correction of apical prolapse. A combination of delayed absorbable and/or permanent sutures are commonly used for the procedure. When permanent sutures are used, risk of suture-related complications is present and patients may require suture removal. In available literature, there is limited data comparing the efficacy and suture-related complications when using different types of sutures. A previou... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
07/20/2023
Locations: Atlantic Health System, Morristown, New Jersey
Conditions: Pelvic Organ Prolapse, Uterovaginal Prolapse, Vaginal Vault Prolapse, Cystocele
Platelet Rich Plasma as an Adjunct Therapy at the Time of Transvaginal Native Tissue Prolapse Surgery
Recruiting
The purpose of the study is to evaluate the surgical outcomes of injecting platelet-rich plasma (PRP) into the vaginal tissue as an adjunct therapy at the time of prolapse surgery
Gender:
Female
Ages:
18 years and above
Trial Updated:
07/06/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Pelvic Organ Prolapse
SCP vs HUSLS for Pelvic Organ Prolapse Repair
Recruiting
The purpose of this study is to compare the effectiveness of R-SCP versus HUSLS for treatment of pelvic organ prolapse.
Gender:
Female
Ages:
Between 18 years and 100 years
Trial Updated:
05/25/2023
Locations: Loma Linda University URO/GYN, Loma Linda, California
Conditions: Pelvic Organ Prolapse, Cystocele, Rectocele, Enterocele
Vaginal Estrogen and Pelvic Floor Physical Therapy in Women With Symptomatic Mild Prolapse
Recruiting
This is a randomized controlled trial in which women with symptomatic mild pelvic organ prolapse undergoing Pelvic Floor Physical Therapy (PFPT) receive vaginal estrogen versus placebo to see if a combined approach to treatment leads to improvement in clinical outcomes. The investigators predict that PFPT in combination with vaginal estrogen will lead to decreased pelvic floor symptoms and improved anatomical support corroborated by biomarker data.
Gender:
Female
Ages:
Between 40 years and 80 years
Trial Updated:
02/07/2023
Locations: Magee-Womens Hospital, University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Pelvic Organ Prolapse