There are currently 65 active clinical trials seeking participants for Pregnancy research studies. The states with the highest number of trials for Pregnancy participants are California, New York, Pennsylvania and Texas.
Maternal Smoking Cessation and Pediatric Obesity Prevention
Recruiting
The objective of this study is to test the effect of smoking cessation in pregnancy or in lactation on preventing rapid infant adiposity gain. Investigators propose a randomized, controlled experiment among smoking pregnant women from 1st prenatal care visit through 6 months of postpartum period. Two-phase randomization will be applied to separate the effects of smoking cessation in two different critical periods (i.e., pregnancy and lactation) on infant adiposity gain. Investigators will first... Read More
Gender:
FEMALE
Ages:
Between 18 years and 39 years
Trial Updated:
07/25/2025
Locations: Division of Behavioral Medicine Department of Pediatrics Jacobs School of Medicine and Biomedical Sciences State University of New York at Buffalo, Buffalo, New York
Conditions: Childhood Obesity, Smoking, Cigarette, Pregnancy
Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years
Recruiting
The goal of this clinical trial is to test the effectiveness of evidence-based Screening, Brief Intervention, and Referral to Treatment (SBIRT) among adult patients who screen positive to one or more risky alcohol or substance use behaviors while seeking care at a sexual and reproductive health (SRH) clinic. The main questions it aims to answer are: * Does SBIRT impact patients' alcohol and substance use, SRH, mental health, physical health, quality of life, and wellbeing? * Does SBIRT effecti... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/22/2025
Locations: Greater Boston Health Center, Boston, Massachusetts +3 locations
Conditions: Alcohol-Related Disorders, Substance-Related Disorders, Mental Health, Reproductive Health, Sexual Health, Sexually Transmitted Diseases, Contraception, Maternal Health, Pregnancy, Women's Health
Development of a Lifestyle Physical Activity Intervention to Reduce Risk for Perinatal Cannabis Use - RCT
Recruiting
The overall goal of this pilot study is to develop and preliminarily evaluate an LPA intervention designed to reduce cannabis use during pregnancy.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/16/2025
Locations: Butler Hospital, Providence, Rhode Island
Conditions: Pregnancy
Development of a Lifestyle Physical Activity Intervention to Reduce Risk for Perinatal Cannabis Use
Recruiting
This study will recruit 20 women who are high risk for prenatal cannabis use for a 12-week program of using the tracker and receiving a Lifestyle Physical Activity program. The primary outcomes will be self reported percent days of cannabis use and physical activity. Secondary outcomes include self -reported measures of depression and anxiety symptoms, adaptive coping, and self-efficacy for cannabis abstinence.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/16/2025
Locations: Butler Hospital, Providence, Rhode Island
Conditions: Pregnancy, Cannabis
A Repository to Study Host-Microbiome Interactions in Health and Disease
Recruiting
Background: The microbiome is the bacteria and other microorganisms that live inside and on the body. The microbiome is important for our health. Researchers study how the microbiome help people stay healthy. They study how the microbiome affects the body when people get sick. To do this research, they need samples of the microbiome living on the bodies of many people. The purpose of this natural history study is to collect microbiome samples in a repository. These samples will be used for futu... Read More
Gender:
ALL
Ages:
All
Trial Updated:
07/15/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Healthy Controls, Pregnancy, Pediatric Illnesses, Inflammatory Diseases
Pregnancy Surveillance Program of Patients Exposed to Epidiolex/Epidyolex During Pregnancy
Recruiting
The purpose of this study is to evaluate pregnancy-related health outcomes in participants who are exposed to Epidiolex/Epidyolex during pregnancy and their infant up to 12 months of life.
Gender:
FEMALE
Ages:
All
Trial Updated:
07/10/2025
Locations: United Biosource LLC, Morgantown, West Virginia
Conditions: Maternal Complications, Pregnancy Complication, Birth Outcomes, Adverse, Pregnancy
Maternal Fetal Device Performance Twins
Recruiting
Maternal Fetal Monitoring devices assist the health care professional in acquiring, monitoring, and storing fetal and maternal physiologic data which support clinical decision making for pregnant women and assesses the overall fetal health status during pregnancy and delivery. This study aims to support a new maternal fetal monitoring device with clinical data by collecting simultaneous, continuous, external, distinguishable FHRs from twin pregnancies using ultrasound Doppler transducers from th... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/10/2025
Locations: Element Materials Technology, Louisville, Colorado
Conditions: Pregnancy
Cognitive Processing Therapy (CPT) for Perinatal Posttraumatic Stress Disorder (PTSD)
Recruiting
Pregnant women with a primary diagnosis of posttraumatic stress disorder (PTSD) (PTSD Checklist for DSM-5 (PCL-5) score \> 33) will be randomized to receive conventional cognitive processing therapy (CPT) (60-min session once/week for 12 weeks) or massed CPT (mCPT) (an intensive schedule of 12 60-min sessions over 5 days, approximately 2-3 sessions per day) via telemedicine, for treatment of PTSD. The research aims will be three-fold: (1) Evaluate the relative efficacy and tolerability of CPT vs... Read More
Gender:
FEMALE
Ages:
Between 18 years and 46 years
Trial Updated:
07/08/2025
Locations: University of Texas at Austin, Dell Medical School, Department of Psychiatry, Austin, Texas
Conditions: Posttraumatic Stress Disorder (PTSD), Pregnancy
Induction of Labor in Morbidly Obese Patients
Recruiting
The goal of this randomized control trial is to compare different doses of Misoprostol (25 mcg vs 50 mcg) in induction of labor (IOL) in morbidly obese patients with BMI \>40. It is known that morbid obesity is a risk factor for failed IOL and ultimately cesarean delivery (CD.) If the rates of vaginal delivery in this population can improve, then surgical morbidity can be reduced in these patients.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/02/2025
Locations: University of Maryland Medical Center, Baltimore, Maryland
Conditions: Morbid Obesity, Pregnancy
Progesterone to Enhance the Efficacy and Success of Expectantly Managed Preterm Severe/Superimposed Preeclampsia
Recruiting
The purpose of this study is to learn if giving 17-hydroxyprogesterone caproate (17 OHPC) to mothers with preeclampsia diagnosed before 34 weeks gestation improves mother and baby outcomes.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
07/02/2025
Locations: Winfred L. Wiser Hospital, Jackson, Mississippi
Conditions: Pregnancy, Preeclampsia (PE)
Feasibility of an ADAPTive Intervention to Improve Food Security and Maternal-Child Health
Recruiting
Food insecurity affects up to 30% of pregnancies and leads to worse health in pregnant people and their children, including an increased risk of gestational diabetes, pre-term birth, and future cardiometabolic chronic conditions (e.g., type 2 diabetes and obesity). Interventions are being utilized to address food insecurity in clinical care settings, but patients differ in the support needed to reduce food insecurity and health systems have limited resources to invest in these interventions. Rat... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
06/26/2025
Locations: Wake Forest University Health Sciences, Winston-Salem, North Carolina
Conditions: Food Insecurity, Pregnancy
Comparing Game Facilitated Interactivity to Genetic Counseling for Prenatal Screening Education
Recruiting
Advancements in prenatal genetic screening have significantly improved the identification of chromosomal abnormalities and heritable conditions during pregnancy, yet current standards for patient education in this domain are largely ineffective. The most effective approach to education about prenatal screening is one-on-one genetic counseling, but due to the limited number of counselors this is not feasible, especially in rural and frontier areas. The investigators will address this national pro... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/16/2025
Locations: University of Alabama, Birmingham, Alabama +2 locations
Conditions: Genetic Counseling, Shared Decision Making, Pregnancy, Genetic Testing, Prenatal Disorder