There are currently 6 active clinical trials seeking participants for Psychotic Disorders research studies. The states with the highest number of trials for Psychotic Disorders participants are California, New York, Florida and Ontario.
A Novel Peer-Delivered Recovery-Focused Suicide Prevention Intervention for Veterans With Serious Mental Illness
Recruiting
Suicide is a major public health concern, particularly among Veterans with serious mental illness (SMI, i.e., psychotic disorders or bipolar disorders). Wellness Recovery Action Plan (WRAP) is a well-established evidence-based practice for those with SMI that centers on identifying warning signs of mental illness, developing wellness tools for functional independence, planning for day-to-day effective living within one's community, and building an action plan to create a valued life worth living... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/05/2025
Locations: VA San Diego Healthcare System, San Diego, CA, San Diego, California
Conditions: Psychotic Disorders, Bipolar Disorders, Suicidal Ideation, Suicide, Attempted
Clinical Study Evaluating Pharmacogenomics-informed Pharmacotherapy Versus Dosing as Usual in Psychiatric Disorders
Recruiting
A 24-week, patient- and rater-blinded, two-arm, parallel-group controlled, and multi-centre randomized clinical trial (RCT) to establish the benefits of pharmacogenetics-informed pharmacotherapy versus dosing as usual (DAU) in psychiatric patients suffering from mood, anxiety, or psychotic disorders.
Gender:
ALL
Ages:
Between 16 years and 65 years
Trial Updated:
06/30/2025
Locations: SUNY Upstate Medical University, Department of Psychiatry and Behavioural Sciences, Syracuse, New York +8 locations
Conditions: Mood Disorders, Anxiety Disorders, Psychotic Disorders
A Preventive Behavioral Intervention for Young Adults With Psychotic Experiences
Recruiting
This is a randomized controlled trial testing the efficacy of Resilience Training in college students with elevated transdiagnostic risk for developing a serious mental illness.
Gender:
ALL
Ages:
Between 18 years and 30 years
Trial Updated:
04/14/2025
Locations: Massachusetts General Hospital, Charlestown, Massachusetts
Conditions: Psychotic Disorders, Mood Disorders, Anxiety Disorders
Development of a Transdiagnostic Intervention for Adolescents at Risk for Serious Mental Illness
Recruiting
This research study aims to develop a brief group-based treatment called Resilience Training for Teens, then to test how well it protects high school students with mild symptoms of depression, anxiety, or having unusual feelings from developing mental illnesses.
Gender:
ALL
Ages:
Between 14 years and 19 years
Trial Updated:
05/21/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Anxiety Disorders, Psychotic Disorders, Depressive Disorder, Psychosocial Functioning
Siltuximab in Schizophrenia
Recruiting
This study is a Phase 1 clinical trial to determine the safety, tolerability, and efficacy of Siltuximab (Sylvant) as an adjunct to antipsychotic medications in stable outpatients with schizophrenia. Siltuximab (structural formula C6450H9932N1688O2016S50) is a recombinant chimeric (human-murine) anti-human interleukin-6 (IL-6) monoclonal antibody. Siltuximab is formulated as a concentrate for solution for infusion, and will be administered by intravenous infusion. The investigators propose a 9-... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
07/20/2023
Locations: Augusta University, Augusta, Georgia
Conditions: Schizophrenia, Psychotic Disorders
Tocilizumab in Schizophrenia
Recruiting
This study is a Phase 1 clinical trial to determine the safety, tolerability, and efficacy of Tocilizumab (Actemra) as an adjunct to antipsychotic medications in stable outpatients with schizophrenia. Tocilizumab (structural formula C6428H9976N1720O2018S42) is a recombinant humanized anti-human interleukin-6 (IL-6) receptor monoclonal antibody of the immunoglobulin G1 (IgG1) subclass. Tocilizumab is formulated as a concentrate for solution for infusion, and will be administered by intravenous in... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
07/20/2023
Locations: Augusta University, Augusta, Georgia
Conditions: Schizophrenia, Psychotic Disorders