Search
Smoking Cessation Clinical Trials
A listing of 55 Smoking Cessation clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 55
There are currently 55 active clinical trials seeking participants for Smoking Cessation research studies. The states with the highest number of trials for Smoking Cessation participants are California, Ontario, Florida and New York.
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Offer
Lose Weight with GLP-1 Medications
Recruiting
Policy Lab has partnered with OnlineSemaglutide.org to offer trusted access to semaglutide and other GLP-1 medications, including generic alternatives to Ozempic® and Wegovy®.
GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.
As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.
GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.
As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.
Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
Reducing Tobacco Smoking: a Transcranial Direct Current Stimulation (TDCS) Telehealth Study
Recruiting
The study aims to evaluate the feasibility of using Dorsolateral Prefrontal Cortex (DLPFC) Transcranial Direct Current Stimulation (tDCS) as a tool to decreasing distress and cigarette smoking. 46 participants currently smoking cigarettes, and seeking to decrease cigarette use will be recruited.
Gender:
ALL
Ages:
Between 21 years and 75 years
Trial Updated:
07/30/2025
Locations: Wake Forest University Health Sciences, Winston-Salem, North Carolina
Conditions: Smoking Cessation
Smoking Cessation Program in the Construction Sector
Recruiting
The main objective of this study is to identify the optimal adaptive smoking cessation program for the construction sector in terms of effectiveness, cost-effectiveness, and potential implementation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/25/2025
Locations: Don Soffer Clinical Research Center, Miami, Florida
Conditions: Smoking Cessation, Tobacco Use Cessation, Tobacco Smoking
A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home
Recruiting
The purpose of this study is to evaluate how using an indoor air quality monitor can promote a smoke-free home for cancer patients who are enrolled in MSK's Tobacco Treatment Program.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/23/2025
Locations: Memorial Sloan Kettering Basking Ridge (Consent only), Basking Ridge, New Jersey +7 locations
Conditions: Smoking, Smoking Cessation, Smoking Reduction, Smoking Habit, Smoking Behaviors, Smoking, Tobacco, Smoking, Cigarette, Smoking (Tobacco) Addiction, Tobacco Use, Tobacco Smoking
CONNECT Cancer Survivors With Tobacco Treatment
Recruiting
The purpose of this study is to evaluate the comparative effectiveness of two different informatics-enabled implementation strategies on increasing tobacco treatment and improving smoking cessation rates for cancer control and prevention. This will be done via a two-arm pragmatic cluster randomized trial (CRT) to test the effectiveness of nudges to change (ELEVATE-S) vs. quit-focused usual care (ELEVATE) in increasing tobacco treatment (use of medication, brief advice, or referral to external co... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/21/2025
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Tobacco Use, Tobacco Use Cessation, Smoking Cessation, Nicotine Addiction, Tobacco Smoking
Contingency Management to Promote Smoking Cessation
Recruiting
Many hospitals and outpatient clinics often refer people who smoke to quitlines and provide prescriptions for smoking cessation medications, but patients rarely fully engage in counseling or use their cessation medications. This is a single-arm, open-label pilot study to provide feasibility metrics for a text-based contingency management (CM) intervention to increase engagement in smoking cessation treatment. All participants (N=20) will be referred to a state quitline and will receive a prescri... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/17/2025
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Smoking Cessation
A Pragmatic Trial of Chronic Disease Approaches to Ameliorate Tobacco Related Cardiovascular Disease Health Disparities
Recruiting
This project will evaluate a proactive outreach intervention for tobacco cessation among primary care BIPOC populations who smoke in two health systems across the region. Compared with Whites, BIPOC populations in the US experience disproportionate health consequences from commercial cigarette use. Few evidence-based cessation treatments (EBCTs) have been specifically developed, evaluated, or implemented for BIPOC populations. Moreover, uptake of EBCT (e.g. medication, counseling) is lower among... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/14/2025
Locations: Hennepin Healthcare, Minneapolis, Minnesota +2 locations
Conditions: Tobacco Use Cessation, Cardiovascular Diseases, Tobacco Use, Smoking, Smoking Cessation
The Options 2 Study
Recruiting
The goal of this clinical trial is to investigate how well nicotine pouches and nicotine mini lozenges serve as substitutes for cigarettes when people try to switch from smoking to using these alternate nicotine products.
Participants will:
* Use nicotine pouches, nicotine mini lozenges, or no study product for a week and then try not to smoke for 3 weeks.
* Have 6 in-person research visits and 1 follow-up call
* Complete questionnaires at each study contact and use a smartphone app to record... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
07/14/2025
Locations: University of Wisconsin, Madison, Wisconsin
Conditions: Smoker, Smoking Cessation
American Indian Smokefree Native RCT
Recruiting
The aim of this clinical trial is to test the efficacy of a culturally aligned digital smoking cessation resource for American Indian persons who smoke, via a remotely conducted randomized controlled trial.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/11/2025
Locations: Masonic Cancer Center, Minneapolis, Minnesota
Conditions: Smoking Cessation
Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and Children
Recruiting
The investigators aim to address the following specific aims:
* Determine the efficacy of Prog in preventing postpartum smoking relapse and reducing smoking relapse risk factors.
* Examine the effects of this maternal smoking intervention on infant health.
* Examine racial and ethnic differences in intervention outcomes.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
07/06/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Smoking, Smoking Cessation, Smoking Reduction
Actívatexto: Advancing Smoking Cessation and Physical Activity Among Latinos
Recruiting
The purpose of this randomized controlled trial is to assess the efficacy of Actívatexto (Aim 1) and the mediators of the presumed treatment effect (Aim 2) among Latino adults who smoke. Actívatexto is a mobile intervention that integrates four components: 1) a text messaging program that promotes both smoking cessation and physical activity, 2) wearable devices to monitor physical activity, 3) smoking cessation pharmacotherapy \[i.e., nicotine replacement therapies (NRT)\], and 4) an online das... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/03/2025
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Smoking, Smoking Cessation, Physical Inactivity
The Avenues Study: Dual Use Cessation
Recruiting
The overarching goal of this research is to determine the most effective approach for helping dual users of cigarettes and electronic nicotine delivery systems (ENDS) quit smoking. 500 participants will be enrolled and can expect to be on study for 12 months.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
06/30/2025
Locations: University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin
Conditions: Smoking Cessation, Electronic Cigarette Use
Healthy Family Project: Tobacco Use and Smoke Exposure in Asian American Communities
Recruiting
This study evaluates whether the Smokefree Family Living (SFL) intervention improves quit rates (smoking cessation) and exposure to tobacco contamination that stays in items such as, carpets, walls, and furniture, even after the smoke has cleared (third-hand smoke (THS)) among Chinese American smokers and their non-smoking household members. Smoking remains high among Chinese American males with limited ability to speak English. This causes the non-smoking household members to be exposed to THS,... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/25/2025
Locations: University of California, San Francisco, San Francisco, California
Conditions: Tobacco-Related Carcinoma, Smoking Cessation
1 - 12 of 55