There are currently 54 active clinical trials seeking participants for Smoking Cessation research studies. The states with the highest number of trials for Smoking Cessation participants are California, Ontario, Florida and New York.
Wellness Intervention for Smoking and HIV
Recruiting
The investigators propose to use a parallel group, randomized controlled trial to test the efficacy of a 13-week personalized approach to reducing smoking intervention versus a second approach using a different health intervention on smoking cessation, healthy sleep metrics, and biomarkers of cardiovascular risk in a sample of 200 treatment-seeking smokers who are adults living with HIV (ALHIV). To enroll in the study, treatment-seeking ALHIV smokers will undergo phone and in-person study eligib... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
08/14/2025
Locations: Banner University Medical Center Phoenix, Phoenix, Arizona +1 locations
Conditions: HIV, Sleep, Smoking Cessation, Cardiovascular Diseases
Refer2Quit: Evaluating a Proactive, Tailored, Population Health Approach for Tobacco Treatment for Household Smokers Through a Pediatric Care Network
Recruiting
The goal of this clinical trial is to compare the reach and effectiveness of the Refer2Quit intervention for increasing tobacco use treatment and quit rates among household members who smoke versus a treatment as usual group. This clinical trial also aims to study household member and pediatric patient characteristics that are associated with reach and effectiveness of Refer2Quit.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Conditions: Smoking, Smoking Cessation, Second Hand Tobacco Smoke
Overcoming Nicotine Dependence to Enable Quitting
Recruiting
Tobacco use disorder is a chronic, relapsing health condition that necessitates a chronic care approach. However, traditional smoking cessation treatment programs allocate nearly all their resources only to those smokers who are willing to set a quit date. This is problematic because few smokers are ready to set a quit date at any given time, and a smoker's stated intention to quit can change rapidly. One novel potential treatment strategy is to foster practice quitting (PQ), defined as attempt... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/13/2025
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Tobacco Use, Smoking Cessation, Smoking Behaviors, Nicotine Dependence, Nicotine Withdrawal
Healing Within: Mindfulness Smoking Cessation Intervention
Recruiting
Using a highly participatory approach, this study will assess the feasibility, acceptability, and satisfaction with a culturally tailored, trauma-informed smoking cessation intervention for Northern Plains Tribal women who have experienced intimate partner violence. If successful, other American Indian Tribes and Tribal communities can adapt this innovative smoking cessation curriculum for their communities.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
08/05/2025
Locations: Black Hills Center for American Indian Health, Rapid City, South Dakota
Conditions: Smoking Cessation
Reducing Tobacco Smoking: a Transcranial Direct Current Stimulation (TDCS) Telehealth Study
Recruiting
The study aims to evaluate the feasibility of using Dorsolateral Prefrontal Cortex (DLPFC) Transcranial Direct Current Stimulation (tDCS) as a tool to decreasing distress and cigarette smoking. 46 participants currently smoking cigarettes, and seeking to decrease cigarette use will be recruited.
Gender:
ALL
Ages:
Between 21 years and 75 years
Trial Updated:
07/30/2025
Locations: Wake Forest University Health Sciences, Winston-Salem, North Carolina
Conditions: Smoking Cessation
Smoking Cessation Program in the Construction Sector
Recruiting
The main objective of this study is to identify the optimal adaptive smoking cessation program for the construction sector in terms of effectiveness, cost-effectiveness, and potential implementation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/25/2025
Locations: Don Soffer Clinical Research Center, Miami, Florida
Conditions: Smoking Cessation, Tobacco Use Cessation, Tobacco Smoking
A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home
Recruiting
The purpose of this study is to evaluate how using an indoor air quality monitor can promote a smoke-free home for cancer patients who are enrolled in MSK's Tobacco Treatment Program.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/23/2025
Locations: Memorial Sloan Kettering Basking Ridge (Consent only), Basking Ridge, New Jersey +7 locations
Conditions: Smoking, Smoking Cessation, Smoking Reduction, Smoking Habit, Smoking Behaviors, Smoking, Tobacco, Smoking, Cigarette, Smoking (Tobacco) Addiction, Tobacco Use, Tobacco Smoking
CONNECT Cancer Survivors With Tobacco Treatment
Recruiting
The purpose of this study is to evaluate the comparative effectiveness of two different informatics-enabled implementation strategies on increasing tobacco treatment and improving smoking cessation rates for cancer control and prevention. This will be done via a two-arm pragmatic cluster randomized trial (CRT) to test the effectiveness of nudges to change (ELEVATE-S) vs. quit-focused usual care (ELEVATE) in increasing tobacco treatment (use of medication, brief advice, or referral to external co... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/21/2025
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Tobacco Use, Tobacco Use Cessation, Smoking Cessation, Nicotine Addiction, Tobacco Smoking
Contingency Management to Promote Smoking Cessation
Recruiting
Many hospitals and outpatient clinics often refer people who smoke to quitlines and provide prescriptions for smoking cessation medications, but patients rarely fully engage in counseling or use their cessation medications. This is a single-arm, open-label pilot study to provide feasibility metrics for a text-based contingency management (CM) intervention to increase engagement in smoking cessation treatment. All participants (N=20) will be referred to a state quitline and will receive a prescri... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/17/2025
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Smoking Cessation
A Pragmatic Trial of Chronic Disease Approaches to Ameliorate Tobacco Related Cardiovascular Disease Health Disparities
Recruiting
This project will evaluate a proactive outreach intervention for tobacco cessation among primary care BIPOC populations who smoke in two health systems across the region. Compared with Whites, BIPOC populations in the US experience disproportionate health consequences from commercial cigarette use. Few evidence-based cessation treatments (EBCTs) have been specifically developed, evaluated, or implemented for BIPOC populations. Moreover, uptake of EBCT (e.g. medication, counseling) is lower among... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/14/2025
Locations: Hennepin Healthcare, Minneapolis, Minnesota +2 locations
Conditions: Tobacco Use Cessation, Cardiovascular Diseases, Tobacco Use, Smoking, Smoking Cessation
The Options 2 Study
Recruiting
The goal of this clinical trial is to investigate how well nicotine pouches and nicotine mini lozenges serve as substitutes for cigarettes when people try to switch from smoking to using these alternate nicotine products. Participants will: * Use nicotine pouches, nicotine mini lozenges, or no study product for a week and then try not to smoke for 3 weeks. * Have 6 in-person research visits and 1 follow-up call * Complete questionnaires at each study contact and use a smartphone app to record... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
07/14/2025
Locations: University of Wisconsin, Madison, Wisconsin
Conditions: Smoker, Smoking Cessation
American Indian Smokefree Native RCT
Recruiting
The aim of this clinical trial is to test the efficacy of a culturally aligned digital smoking cessation resource for American Indian persons who smoke, via a remotely conducted randomized controlled trial.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/11/2025
Locations: Masonic Cancer Center, Minneapolis, Minnesota
Conditions: Smoking Cessation