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Stress Clinical Trials
A listing of 61 Stress clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 61
There are currently 61 active clinical trials seeking participants for Stress research studies. The states with the highest number of trials for Stress participants are California, Massachusetts, Florida and New York.
Featured Trial
Paid Clinical Studies Nationwide
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Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Offer
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Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
State-dependent Interoception, Value-based Decision-making, and Introspection
Recruiting
Background:
Negative emotional states can affect a person s behavior as they make decisions. For example, hunger may make people more impatient; they may then make riskier choices. Other negative emotional states that can change behavior include stress, pain, and sadness. By learning more about how emotions affect thinking and behavior in healthy people, researchers hope to better understand how to identify and treat people with mental disorders.
Objective:
To learn how negative emotions affe... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
07/31/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Stress, Pain, Emotions, Craving, Frustration
Remote Mindfulness Training Following Early Life Adversity 2
Recruiting
This pilot study aims to evaluate the effects of a 10-week online Mindfulness-Based Stress Reduction (MBSR) intervention on stress and inflammatory outcomes in a sample of emerging adults with a history of early life adversity. 15 participants (ages 18-29) with a history of childhood trauma will receive online, group-based MBSR sessions over 10 weeks. At pre- and post-intervention, participants will complete laboratory assessments, including self-report questionnaires and blood sample collection... Read More
Gender:
ALL
Ages:
Between 18 years and 29 years
Trial Updated:
07/22/2025
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Intranasal Oxytocin Intervention for Caregivers to Persons With Dementia
Recruiting
More than 15 million family caregivers provide support for individuals with Alzheimer's disease (AD) or related dementias. This number is expected to grow with the increasing population of persons with dementia (PWD). Stress in caregivers to older adults with chronic diseases is already a significant public health issue because it is associated with multiple negative physical and mental health outcomes for the caregiver (e.g., depression, cardiovascular disease) and can negatively impact the hea... Read More
Gender:
FEMALE
Ages:
50 years and above
Trial Updated:
07/21/2025
Locations: University of Nebraska Medical Center, Department of Psychiatry, Omaha, Nebraska
Conditions: Stress
Building Resilience at Schools: Emotional and Biological Assessment and Treatment of Traumatic Stress
Recruiting
In the last four years alone, residents of Puerto Rico have experienced a slew of natural disasters including Hurricane Maria in 2017, earthquakes in 2019 and 2020, the continued COVID-19 pandemic from 2020-2022, and most recently Hurricane Fiona. This series of distressing events can lead to an increased need for mental health resources and trauma treatment. Furthermore, the unique single-district structure of the Puerto Rican education system allows for the efficient dissemination of potential... Read More
Gender:
ALL
Ages:
Between 11 years and 17 years
Trial Updated:
07/15/2025
Locations: Stanford University, Palo Alto, California +2 locations
Conditions: Post Traumatic Stress Disorder, Complex Posttraumatic Stress Disorder, Stress, Burn Out, Mental Health Issue
Cannabidiol (CBD) and Stress Response: Psychobiological Mechanisms
Recruiting
The aim of this study is to determine the effects of regular cannabidiol (CBD) use on the psychobiological mechanisms of the stress response. This will be achieved by comparing acute stress responses of adults who either use or do not use CBD regularly. Correlates of CBD use, including tobacco use, will be collected.
Gender:
ALL
Ages:
Between 21 years and 70 years
Trial Updated:
07/07/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Disrupted Connections: The Impact of Acute Stress on Memory Integration
Recruiting
The goal of this study is to better understand how stress impacts people's ability to learn across their experiences and link new information to what they already know. The investigators will compare performance on a memory task between stressed and non-stressed participants. This memory task requires people to integrate knowledge across learning experiences (think: having to "connect the dots", draw inferences, and generalize your knowledge to new situations and scenarios). Cortisol, the brain'... Read More
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
06/27/2025
Locations: Nevada State University, Henderson, Nevada
Conditions: Stress, Control Condition
Internet Based Psychological Support
Recruiting
The investigators have developed interactive, multimedia-intensive, computer-based treatment programs that include depression (Problem-Solving Therapy), stress management, and conflict management. Together the three modules are called PATH.
The problem-solving module is based on an evidence-based psychotherapy called Problem-Solving Therapy in which depressed patients identify problems in their lives and work through a structured format for solving these problems. We have subjected the problem-... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/24/2025
Locations: Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
Cocooned Moms Study
Recruiting
The Cocooned Moms Study is a pre- and post-design study primarily aimed at reducing stress, depressive symptoms, and blood pressure among expectant Black women by providing them with free access to the InovCares mobile app. InovCares is a culturally-sensitive telehealth platform designed for community-based care coordination in maternal care. It also offers a culturally tailored maternal mental health program, which provides access to resources addressing social determinants of health, cognitive... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
06/13/2025
Locations: University Of Miami, Miami, Florida +1 locations
Perceptual Influences From Smoking Cannabis: an Experimental Study
Recruiting
The purpose of the study is to better understand the effects of cannabis in relation to mental and physical states including its relationship with mood, cognition, perception including the experience of temperature and pain, and heart rate.
We expect that participants will be in this research study for approximately one week. The total amount of time that participants will spend completing study tasks will be about 2.5 hours across two separate in-person visits.
Gender:
ALL
Ages:
Between 21 years and 65 years
Trial Updated:
06/12/2025
Locations: University of Colorado at Boulder, Boulder, Colorado
Conditions: Cannabis Use, Stress
The Impact of Music Medicine on Preterm Brain Development and Behavior
Recruiting
The investigators are conducting a two-site randomized control trial with the aim of defining the impact of music (M) without or with parent voice (MPV) on very preterm infants' acute and cumulative stress, intranetwork connectivity on term brain MRI, and language and other neurodevelopmental outcomes at two years corrected age. This is based on the hypothesis that infants in MPV arm are expected to experience the greatest benefit compared with infants receiving standard care.
Gender:
ALL
Ages:
Between 24 weeks and 30 weeks
Trial Updated:
06/12/2025
Locations: Yale New Haven Hospital, New Haven, Connecticut +1 locations
Conditions: Infant Development, Language Development, Prematurity, Stress
Evaluating Stress Management Among Allogeneic HCT Caregivers
Recruiting
The purpose of the study is to understand whether different stress management interventions impact stress among HCT cancer caregivers and patients.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
06/11/2025
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Burden, Stress
A Randomized Controlled Trial to Assess the Impact of Live and Recorded Music-Based Interventions on Pre-operative Stress, Mood, Pain and Biomarkers, in Neurosurgical Patients (Music-STAR Trial)
Recruiting
The study plans to enroll a total of 132 patients. The goal of this study is to measure pre-and post-music intervention changes in patients' vital signs, serum- and plasma-level biomarkers by broad-spectrum proteomics analysis, metabolic analysis, and perceived pain, anxiety, and mood states as measured by validated questionnaires (STAI-S, POMS-SF, and VASP). We will collect demographic information on each participant. Participants will also complete the Brief Musical Experience Questionnaire (B... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/06/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Stress, Pain
1 - 12 of 61