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Stress Disorders, Post-Traumatic Clinical Trials
A listing of 23 Stress Disorders, Post-Traumatic clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 23
There are currently 23 active clinical trials seeking participants for Stress Disorders, Post-Traumatic research studies. The states with the highest number of trials for Stress Disorders, Post-Traumatic participants are California, New York, Texas and Massachusetts.
Featured Trial
Paid Clinical Studies Nationwide
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Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
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Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
Computer Monitor vs Augmented Reality 3MDR for PTSD PTSD: A Randomized Controlled Trial
Recruiting
This is a prospective randomized controlled trial comparing two ways of delivering Motion-assisted, Multi-modular Memory Desensitization and Reconsolidation (3MDR) therapy for posttraumatic stress disorder (PTSD). The study seeks 60 volunteers who have PTSD and are eligible for care in the Department of Defense healthcare system. There will be 10-14 therapy sessions that are 60-90 minutes long, about once a week, and symptoms will be assessed before and after the therapy as well as 3 and 6 month... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/14/2025
Locations: Uniformed Services University, Bethesda, Maryland
Conditions: Stress Disorders, Post-Traumatic
Computational Assessment of GABA Receptor Modulation in PTSD
Recruiting
A substantial majority of Veterans with posttraumatic stress disorder (PTSD) continue to suffer even with the best current medications. Progress in developing more effective medications is hampered by the substantial variability within Veterans with PTSD, meaning the most effective medication likely varies from individual to individual. New scientific tools to help identify distinct subgroups of Veterans with PTSD who are likely to respond to specific medications could help improve treatment in... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
07/11/2025
Locations: VA San Diego Healthcare System, San Diego, CA, San Diego, California
Conditions: Stress Disorders, Post-Traumatic
A Study of a Novel EEG Neurofeedback System for PTSD Treatment
Recruiting
The goal of this clinical trial is to learn if training with the Prism system can reduce PTSD symptoms in US military Veterans and civilians with PTSD. Prism is a form of neurofeedback training that uses EEG signals to promote self-regulation of brain function. The main question this study aims to answer is:
Does Prism training lead to decreased PTSD symptoms in US Veterans and civilians when used in addition to usual PTSD treatment?
Researchers will compare Prism training to a sham training (... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
07/10/2025
Locations: Birmingham VA Medical Center, Birmingham, Alabama +5 locations
Conditions: Stress Disorders, Post-Traumatic
Safety Aid Reduction Treatment for PTSD Among Veterans
Recruiting
The purpose of this project is to examine the acceptability, feasibility, and utility of a safety aid reduction treatment (START) among Veterans with posttraumatic stress disorder (PTSD). It is hypothesized that START will be acceptable, feasible, and will lead to reductions in PTSD symptom severity immediately and over time.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/02/2025
Locations: Southeast Louisiana Veterans Health Care System, New Orleans, LA, New Orleans, Louisiana
Conditions: Stress Disorders, Post-Traumatic
Using the Multiphase Optimization Strategy to Adapt Cognitive Processing Therapy
Recruiting
Cognitive Processing Therapy (CPT) consists of discrete therapeutic components that are delivered across 12 sessions, but most Veterans never reach session 12, and those who drop out receive only 4 sessions on average. Veterans drop out because of time constraints, logistics, and lack of perceived benefit. Unfortunately, Veterans who drop out prematurely may never receive the most effective components of CPT and continue to experience symptom-related distress and numerous other negative outcomes... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/21/2025
Locations: VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor, Michigan +2 locations
Conditions: Stress Disorders, Post-Traumatic
Enhancing PTSD Treatment Outcomes by Improving Patient-Provider Communication
Recruiting
The purpose of this clinical trial is to learn whether existing treatments for posttraumatic stress disorder (PTSD) can be improved. Two treatments for PTSD, cognitive processing therapy (CPT) and prolonged exposure (PE) will be studied. CPT and PE are effective treatments that are widely available, but interventions are needed to improve patient outcomes in these treatments. The investigators have developed an Adjunctive Writing intervention for Amplifying Response and Engagement (AWARE), which... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/25/2025
Locations: National Center for PTSD at VA Boston Healthcare System, Boston, Massachusetts
Conditions: Stress Disorders, Post-Traumatic
Trauma-Informed Guilt Reduction Therapy Compared to Prolonged Exposure
Recruiting
The goal of this clinical trial is to learn if receiving Trauma-Informed Guilt Reduction (TrIGR) Therapy is as effective as receiving Prolonged Exposure Therapy among veterans with PTSD and trauma related guilt. The main questions it aims to answer are:
Will TrIGR be comparable to PE in terms of PTSD symptom reduction? Will it TrIGR be comparable to PE in improving functioning and reducing depression symptoms? Will it be superior in improving trauma-related guilt and shame?
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/16/2025
Locations: Little Rock Veterans Health Care System (LRVHCS), Little Rock, Arkansas +2 locations
Conditions: Stress Disorders, Post-Traumatic
Massed Prolonged Exposure for PTSD in Substance Use Treatment
Recruiting
The goal of this clinical trial is to learn if receiving Prolonged Exposure Therapy for PTSD in massed format (multiple sessions weekly) is as effective as receiving it with sessions once per week among veterans with PTSD and substance use disorder in intensive outpatient substance use treatment. The main questions it aims to answer are:
* Will the massed format help participants complete and benefit from Prolonged Exposure in terms of PTSD symptoms?
* Will it help participants reduce substance... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/16/2025
Locations: VA San Diego Healthcare System, San Diego, California +3 locations
Conditions: Stress Disorders, Post-Traumatic, Substance Use Disorders
Transcutaneous Vagal Nerve Stimulation in Veterans With Posttraumatic Stress Disorder
Recruiting
This study effects the effects of transcutaneous cervical vagal nerve stimulation (tcVNS) or a sham control on brain, physiology, and PTSD symptoms in Veterans with posttraumatic stress disorder (PTSD). Veterans undergo brain imaging and physiological measures in conjunction with traumatic scripts before and after three months of twice daily treatment with tcVNS or sham stimulation at home.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
03/27/2025
Locations: Atlanta VA Medical and Rehab Center, Decatur, GA, Decatur, Georgia
Conditions: Stress Disorders, Post-Traumatic
MDMA for Co-occurring PTSD and OUD After Childbirth
Recruiting
This is an open-label study of the use of MDMA Assisted Therapy for postpartum people with co-occurring Post Traumatic Stress Disorder (PTSD) and Opioid Use Disorder (OUD). The study protocol has been adapted from the Phase 3 studies sponsored by the Multidisciplinary Association for Psychedelic Studies (MAPS) for PTSD. Due to the high rate of concurrence of PTSD and OUD, people with OUD may experience great benefit from the treatment of their PTSD with MDMA-assisted therapy based on the phase 2... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
03/12/2025
Locations: University of New Mexico Health Sciences, Albuquerque, New Mexico
Conditions: Stress Disorders, Post-Traumatic, Opioid Use Disorder
A Randomized Controlled Trial of Coaching Into Care With VA-CRAFT to Promote Veteran Engagement in PTSD Care
Recruiting
Posttraumatic stress disorder (PTSD) afflicts many war Veterans, but often they are reluctant to seek help despite availability of effective treatments. Family members are key sources of support who can help encourage such Veterans to initiate mental health services. Toward that goal, VA provides telephone coaching to family members through its Coaching Into Care (CIC) program to help get their Veterans into care. While CIC enjoys high caller satisfaction, it has shown only modest success gettin... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/25/2025
Locations: VA Palo Alto Health Care System, Palo Alto, CA, Palo Alto, California
Conditions: Stress Disorders, Post-traumatic
Intervention to Enhance Coping and Help-seeking Among Youth in Foster Care
Recruiting
This study will deploy a scalable secondary prevention program that leverages existing foster youth transition services to improve mental health functioning and service use before and after exiting foster care. Our short-term objective is to remotely test a group intervention called Stronger Youth Networks and Coping (SYNC) that targets cognitive schemas influencing stress responses, including mental health help-seeking and service engagement, among foster youth with behavioral health risk. SYNC... Read More
Gender:
ALL
Ages:
Between 16 years and 20 years
Trial Updated:
02/25/2025
Locations: Portland State University, Portland, Oregon
Conditions: Adolescent Behavior, Psychosocial Functioning, Coping Behavior, Help-Seeking Behavior, Utilization, Health Care, Depression, Anxiety, Stress Disorders, Post-Traumatic, Emotion Regulation, Child Welfare
1 - 12 of 23