There are currently 10 active clinical trials seeking participants for Uveitis research studies. The states with the highest number of trials for Autism participants are California, Maryland, Texas and Massachusetts.
RChildUV:Study on Non-infectious Chronic Uveitis in Pediatric Age
NCT06273748
Recruiting
Uveitis is an inflammatory disease of the uvea, one of the highly vascularized fundamental structures of the eye. It is a rare condition in children, with an incidence in the pediatric population ranging from 2% to 14% of all uveitis cases. The diagnosis and management of patients with uveitis rely on a multidisciplinary approach involving an ophthalmologist, a rheumatologist, and an infectious disease specialist to establish the correct diagnosis and assess the involvement of other organs. In I... Read More
Gender:
All
Ages:
Between 1 year and 16 years
Trial Updated:
03/07/2024
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio +4 locations
Conditions: Uveitis
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Genetics of Uveitis
NCT02357238
Recruiting
In order to improve the investigators knowledge about uveitis and the underlying mechanism of disease, the investigators propose collecting blood from patients with uveitis, isolating DNA and sequencing the DNA to identify genetic mutations or associations in these patients.
Gender:
All
Ages:
6 years and above
Trial Updated:
02/14/2024
Locations: Cleveland Clinic Foundation, Cleveland, Ohio
Conditions: Uveitis, Infectious Uveitis
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Imaging of Uveitis Patients Receiving Injectable Fluocinolone Acetonide Implant
NCT04340505
Recruiting
We will prospectively observe patients with uveitis who are either active or were recently active in the previous 6 months and are treated with the i-FA implant. All of the patients will have standard clinical exams at baseline and image quantification of their inflammation using OCT, OCTA and UWFFA (if needed). At baseline, ETDRS vision will be measured. Patients will be followed for 12 months months. During follow-up repeat imaging will be performed along with standard examinations, visual acu... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/14/2024
Locations: Cole Eye Institute Cleveland Clinic Foundation, Cleveland, Ohio
Conditions: Uveitis
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Analysis of Anterior Chamber Inflammation by Optical Coherence Tomography
NCT01746537
Recruiting
A prospective, observational, case series investigating the feasibility of utilizing OCT scans of the anterior chamber of eyes with uveitis.
Gender:
All
Ages:
All
Trial Updated:
02/14/2024
Locations: Cole Eye Institute, Cleveland, Ohio
Conditions: Uveitis
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Safety, Tolerability, and Distribution of Laquinimod Eye Drops : The LION Study
NCT06161415
Recruiting
The LION Study is a prospective, single-center phase 1 clinical trial to evaluate the safety, tolerability, and distribution of Laquinimod administered as topical eye drops for two weeks in human participants.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/15/2024
Locations: Spencer Center for Vision Research at the Byers Eye Institute, Palo Alto, California
Conditions: Uveitis, Inflammation
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Phase 2b Pivotal Study of Izokibep in Non-infectious, Intermediate-, Posterior- or Pan-uveitis
NCT05384249
Recruiting
Izokibep is a small protein molecule that acts as a selective, potent inhibitor of interleukin-17A, to which it binds with high affinity. This study investigates izokibep in subjects with active non-infectious, intermediate-, posterior- or pan-uveitis requiring high-dose steroids.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
02/29/2024
Locations: Clinical Research Site, Phoenix, Arizona +69 locations
Conditions: Uveitis
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Optical Coherence Tomography (OCT) in Uveitis
NCT02026128
Recruiting
Optical Coherence Tomography (OCT) machines are non-contact instruments that can provide micrometer (one one-thousandths) scale imaging of biological tissue. This allows excellent assessment of the white blood and inflammatory cells seen in uveitis, an inflammation of any or all parts of the uvea (iris, ciliary body, choroid).
Gender:
All
Ages:
18 years and above
Trial Updated:
02/08/2024
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Uveitis
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AutoInflammatory Disease Alliance Registry (AIDA)
NCT05200715
Recruiting
Autoinflammatory diseases (AID) are clinical entities characterized by recurrent inflammatory attacks in absence of infection, neoplasm or deregulation of the adaptive immune system. Among them, hereditary periodic syndromes, also known as monogenic AID, represent the prototype of this disease group, caused by mutations in genes involved in the regulation of innate immunity, inflammation and cell death. Based on recent experimental acquisitions in the field of monogenic AID, several immunologic... Read More
Gender:
All
Ages:
All
Trial Updated:
02/17/2023
Locations: National Human Genome Research Institute, Bethesda, Maryland +99 locations
Conditions: Hereditary Autoinflammatory Diseases, Schnitzler Syndrome, Behcet Syndrome, PFAPA Syndrome, Still Disease, Autoinflammatory Syndrome, Unspecified, Uveitis, Scleritis, Vexas Syndrome
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The Use of Two YUTIQ Versus Sham for Treatment of Chronic Non Infectious Intraocular Inflammation Affecting the Posterior Segment
NCT05486468
Recruiting
The Use of Two YUTIQ versus Sham for Treatment of Chronic Non Infectious Intraocular Inflammation Affecting the Posterior Segment (TYNI Trial)
Gender:
All
Ages:
18 years and above
Trial Updated:
10/27/2022
Locations: Texas Retina Associates, Plano, Texas
Conditions: Uveitis, Uveitis, Posterior, Uveitis, Anterior, Uveitis, Intermediate
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Ocular Pathogen and Transcriptome Investigation Using Comprehensive Sequencing
NCT05286203
Recruiting
This is a multi-center randomized controlled evaluator-masked trial designed to compare metagenomic deep sequencing (MDS) versus standard of care testing for improvement of outcomes for intraocular infections. Patients with presumed intraocular infections who meet the eligibility criteria will be randomized to receive MDS testing results or not to receive MDS testing results. All patients will receive standard-of-care testing to guide management. Enrolled patients will be followed at week 2, wee... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/05/2022
Locations: University of California San Francisco (UCSF), San Francisco, California
Conditions: Uveitis, Infectious Disease
Register for Updates