The state of Connecticut currently has 4 active clinical trials seeking participants for Endometriosis research studies. These trials are conducted in various cities, including New Haven, Hartford, Farmington and Stamford.
Cardiovascular Disease Risk in Women With Endometriosis
Recruiting
To test the hypothesis that estrogen suppression impairs endothelial dysfunction in endometriosis.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
01/23/2025
Locations: Yale School of Medicine, New Haven, Connecticut
Conditions: Endometriosis
Endometriosis and Microvascular Dysfunction; Simvastatin and Duavee
Recruiting
Purpose: To determine the effects of SERM and simvastatin interventions on endothelial dysfunction in women with endometriosis. Hypothesis: Treatment with the SERM (bazedoxifene + conjugated estrogen) or with simvastatin will decrease systemic inflammation and improve specific measures of cardiovascular function including endothelium-dependent vasodilation.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
11/04/2024
Locations: The John B. Pierce Laboratory, New Haven, Connecticut
Conditions: Endometriosis
Cancer Driving Mutations in Endometriosis Lesions and Development of Progesterone Resistance
Recruiting
This study will test the hypothesis that the molecular changes present in ectopic endometriosis lesions correlate with progesterone-resistant disease (using the criteria defined in this study) and are present in matched eutopic endometrium.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
08/06/2024
Locations: Yale School of Medicine, New Haven, Connecticut
Conditions: Endometriosis, Endometrial Diseases
Pre-IVF Treatment With a GnRH Antagonist in Women With endometriosis_temp
Recruiting
A Phase 3 clinical trial of oral GnRH antagonist pre-treatment for women with endometriosis who are undergoing IVF, with a primary outcome of live birth rate. The investigators' central hypothesis is that in infertile woman with endometriosis undergoing in vitro fertilization-embryo transfer (IVF-ET), live birth rates will improve in those pretreated with GnRH antagonist compared to those not pretreated with GnRH antagonist.
Gender:
Female
Ages:
Between 18 years and 40 years
Trial Updated:
04/16/2024
Locations: Yale School of Medicine Dept.of Ob/Gyn & Reproductive Sciences, New Haven, Connecticut
Conditions: Infertility, Endometriosis