The state of Connecticut currently has 18 active clinical trials seeking participants for Healthy research studies. These trials are conducted in various cities, including New Haven, Hartford, Farmington and Stamford.
Evaluation of [18F]APN-1607 as a PET Biomarker
NCT05005819
Recruiting
The overall goal of this protocol is to evaluate [18F]APN-1607 as a PET radiotracer for measuring longitudinal change in tau pathology in participants with PSP.
Gender:
All
Ages:
Between 50 years and 80 years
Trial Updated:
10/06/2023
Locations: Invicro, New Haven, Connecticut
Conditions: Progressive Supranuclear Palsy, Healthy Volunteers
Register for Updates
Aberrant Synaptic Plasticity in Cocaine Use Disorder: A 11C-UCB-J PET Study
NCT04721418
Recruiting
The purpose of this research study is to measure synaptic density in the brain comparing individuals with cocaine use disorder to healthy controls.
Gender:
All
Ages:
Between 21 years and 60 years
Trial Updated:
10/02/2023
Locations: Connecticut Mental Health Center, New Haven, Connecticut
Conditions: Cocaine Use Disorder, Healthy Controls
Register for Updates
Effects of Hepatic Ultrasound on Metabolic Homeostasis
NCT04622683
Recruiting
The purpose of this study is to define the effect of ultrasound exposure of the liver in the region of the porta hepatis on glucose homeostasis and insulin resistance in healthy subjects.
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
08/22/2023
Locations: Yale-New Haven Hospital, New Haven, Connecticut
Conditions: Healthy, Insulin Resistance
Register for Updates
CBD-Microglia PET Study
NCT04398719
Recruiting
This study aims to examine the effect of cannabidiol (CBD) pre-treatment on brain microglial activation in healthy human subjects. Secondarily, this study aims to examine the effect of cannabidiol (CBD) pre-treatment on central pain-sensitization in healthy human subjects.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
07/13/2023
Locations: Connecticut Mental Health Center, New Haven, Connecticut
Conditions: CBD, Healthy
Register for Updates
SV2A & TSPO PET Imaging Measures to Reveal Mechanisms of HIV Neuropathogenesis During Antiretroviral Therapy
NCT05586581
Recruiting
The purpose of this study is to longitudinally characterize and evaluate changes in synaptic density in the brain using novel positron-emission tomography (PET) scans; magnetic resonance imaging (MRI), and clinical laboratory markers associated with HIV-related injury in the central nervous system. This study will test hypotheses relating to the presence and mechanisms of aberrant brain structure at the synaptic level in living humans with virologically controlled HIV on antiretroviral therapy.... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
06/26/2023
Locations: Yale School of Medicne, Neuro ID Research Program, New Haven, Connecticut
Conditions: HIV Associated Neurocognitive Disorder, HIV Dementia, HIV Encephalitis, Healthy
Register for Updates
Proof of Mechanism Study to Evaluate Binding of Alfa-synuclein
NCT05274568
Recruiting
The overall goal of this protocol is to: Evaluate [18F]UCB-2897 as an α-synuclein targeted radiopharmaceutical. The primary objective is: • Confirm a specific α -synuclein signal with [18F]UCB-2897 in participants with PD and/or MSA relative to healthy volunteers Secondary and exploratory objectives are: Determine the safety and tolerability of microdose [18F]UCB-2897 Evaluate preliminary dosimetry of [18F]UCB-2897 Additional exploratory objectives are: Determine the pharmacokinetics / me... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/01/2022
Locations: Invicro, New Haven, Connecticut
Conditions: Parkinson Disease, Multisystem Atrophy, Healthy Volunteer
Register for Updates