The state of Connecticut currently has 30 active clinical trials seeking participants for Pain research studies. These trials are conducted in various cities, including New Haven, Hartford, Farmington and Stamford.
Study of BOTOX Injections to Assess Change in Disease Activity and Adverse Events in Adult Female Participants With Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)
Recruiting
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a chronic and debilitating urological complex of disorders characterized by symptoms of bladder pain or discomfort, mostly upon bladder filling, and often accompanied by lower urinary tract symptoms (LUTS). This study will assess how safe and effective BOTOX (onabotulinumtoxinA) is in treating IC/BPS. Adverse events and change in disease symptoms will be evaluated. BOTOX (onabotulinumtoxinA) is an investigational drug being developed for t... Read More
Gender:
Female
Ages:
Between 18 years and 75 years
Trial Updated:
03/21/2024
Locations: Hartford Healthcare Group - Farmington /ID# 241037, Farmington, Connecticut
Conditions: Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)
Patient Retrospective Outcomes (PRO)
Recruiting
This study will evaluate de-identified (anonymous) data in subject medical charts to review the clinical outcomes of various treatment approaches in the treatment of chronic pain.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/08/2024
Locations: Advanced Diagnostic Pain Treatment Centers, New Haven, Connecticut
Conditions: Chronic Pain
Radiofrequency (RF) Ablation Prospective Outcomes Study
Recruiting
The objective of this study is to compile real-world outcomes of Boston Scientific commercially approved radiofrequency (RF) ablation systems in the treatment of patients diagnosed with pain and in use for central nervous system (CNS) applications for other disorders.
Gender:
All
Ages:
0 years and above
Trial Updated:
03/08/2024
Locations: The Spine Wellness Center in Westport, Westport, Connecticut
Conditions: Pain, Chronic
Cannabidiol in Opioid Use Disorder and Chronic Pain
Recruiting
This is a double-blind, randomized, placebo-controlled cross-over human laboratory study with a duration of approximately 3 weeks, during which participants will come to the testing site for a total of five times: one initial screening session, and four experimental sessions where study medication, Cannabidiol (CBD) will be administered, separated by at least 72 hours to limit carryover effects.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
03/05/2024
Locations: Department of Veterans Affairs Hospital, West Haven, Connecticut
Conditions: Chronic Pain
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
Recruiting
The purpose of the chronic pain master protocol is to compare independent pain interventions and establish an overarching structure for the disease-state addenda (DSA) and intervention-specific appendices (ISAs). The ISAs may start independently of other ISAs as interventions become available for clinical testing.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: CMR of Greater New Haven, LLC, Hamden, Connecticut
Conditions: Osteoarthritis, Knee, Diabetic Neuropathic Pain, Chronic Low-back Pain
A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight
Recruiting
The purpose of this study is to evaluate the efficacy and safety of retatrutide in participants who have obesity or overweight (J1I-MC-GZBJ master protocol) including subsets of participants who have knee osteoarthritis (OA) (J1I-MC-GOA1) or who have obstructive sleep apnea (OSA) (J1I-MC-GSA1). This study will last about 89 weeks and will include up to 24 visits.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/29/2024
Locations: Yale University School of Medicine, New Haven, Connecticut +1 locations
Conditions: Obesity, Overweight, Knee Pain Chronic, Knee Osteoarthritis, Obstructive Sleep Apnea
Validation of the Cervicothoracic Differentiation Test
Recruiting
The goal of this clinical trial is to compare the effects of two spinal manipulations in adults between the ages of 18-65 based on the results of a non-invasive clinical test. The main question it aims to answer is: • Does matched or unmatched region of manipulation based on the CTDT result in greater reduction of pain levels and improvement in range of motion in adults with neck pain compared to unmatched manipulations? Participants will be asked to: rate their pain with neck movement, complet... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/28/2024
Locations: University of Hartford, West Hartford, Connecticut
Conditions: Neck Pain
The DISCOVER INOCA Prospective Multi-center Registry
Recruiting
The overall objective of this multi-center registry is to identify specific phenotypes of INOCA with both an anatomic evaluation (coronary angiography and intravascular imaging) and physiologic assessment with the Abbott Coroventis Coroflow Cardiovascular System, and to determine long-term outcomes.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/14/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Ischemia and no Obstructive Coronary Artery Disease, Coronary Microvascular Dysfunction, Coronary Vasospasm, Endothelial Dysfunction, Microvascular Angina, Chest Pain With Normal Coronary Angiography
An Adaptive Walking Intervention to Manage Chronic Pain in Veterans With Opioid Use Disorder Engaged in Opioid Agonist Treatment
Recruiting
Severe chronic pain and opioid use disorder (OUD) occur at significantly higher rates in Veterans compared to the general population. Chronic pain often persists despite engagement in opioid agonist treatment (OAT), the first line treatment for OUD. Recent VA guidelines strongly recommend non-pharmacologic treatment for chronic pain, but individuals with OUD are frequently excluded from pain treatment studies. There is a need for evidence-based pain treatments that compliment OAT for Veterans wi... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/09/2024
Locations: VA Connecticut Healthcare System West Haven Campus, West Haven, CT, West Haven, Connecticut
Conditions: Opioid Use Disorder, Chronic Pain
Postoperative Dexamethasone on Post-Cesarean Pain
Recruiting
Investigating if giving post-operative dexamethasone to patients with a history of opioid use disorder on medication assisted treatment during pregnancy improves their pain scores and decreases their opioid use after cesarean section.
Gender:
Female
Ages:
18 years and above
Trial Updated:
02/05/2024
Locations: Yale New Haven Hospital, New Haven, Connecticut
Conditions: Post-Cesarean Pain, Cesarean Section Complications
TAP Block Using Liposomal Bupivacaine for Post-cesarean Delivery Analgesia- Walking Towards Recovery
Recruiting
The TAP block offers analgesia by blocking the sensory nerves of the anterior abdominal wall. The procedure is performed under ultrasound guidance, after identification of the external oblique, internal oblique and transverse abdominis muscle. Medication is injected in the neurofascial plane between the internal oblique and the tranversus abdominis muscle. Previous studies have demonstrated limited (<24 hour) effect of the block when compared to the use of intrathecal morphine (considered to be... Read More
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
02/02/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Opioid Use, Pain, Acute
Physical Activity Interventions To Heal Chronic Low Back Pain
Recruiting
This study will advance understanding on the mechanisms that mediate improved outcomes for chronic low back pain and provide specific directions for optimizing physical activity interventions for this population.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/23/2024
Locations: University of Connecticut, Storrs, Connecticut
Conditions: Chronic Low Back Pain